The Strategy to Improve the Competitiveness of Indonesian Seaweeds in Global Market

This research is aimed to know the position of Indonesian seaweeds exports\u27 competitiveness in global market, as well as the strategy to improve it. The research uses a quantitative approach, which specifically employs time series type that has been done within 10 years period (2003-2012). The data used are the data of seaweed product by the code product of HS 121220 Seaweeds and other algae (fresh or dried), HS 121221 Seaweeds fit for human consumption, HS 121229 Seaweeds and other algae unfit for human consumption. The data includes the value of Indonesian seaweeds exports commodity, the total of Indonesian exports, the value of seaweeds in global exports, the total of global exports, Indonesian seaweeds imports, Indonesian seaweeds production, and Indonesian seaweeds exports. The data is analyzed using Revealed Comparative Advantage (RCA), Import Dependency Ratio (IDR), Specialized Trading Index (ISP), Commodity Concentration Index (CCI), alongside with Strengths, Weaknesses, Opportunities, and Threats. The result shows that: (1) The RCA of seaweeds commodity though fluctuating but relatively increasing; (2) The Import Dependency Ratio of Indonesian seaweeds though fluctuating but relatively increasing, the fluctuation is due to their inability to produce plus value of ferments; (3) Index of Specialized trading appears to be positive; (4) Commodity Concentration Index of exports and imports though fluctuating but relatively increasing; (5) Indonesia can employ Rapid Growth Strategy. The result recommends Indonesian government to improve the quality of seaweeds products specifically using distribution improvements from farmers to consumer both in industrial scope and domestic consumer

Redução de nitrato e assimilação de amônio em plantas jovens de Hevea brasiliensis cultivadas sob níveis crescentes de nitrato.

As atividades de redutase do nitrato (RN), sintetase da glutamina (GS), sintase do glutamato (GOGAT) e desidrogenase do glutamato (GDH) foram avaliadas em laminas foliares e raizes de seringueira (Hevea brasiliensis Muell. Arg.) com 7 meses de idade, cultivadas em solucao nutritiva contendo 0, 1 ou 12 mM de nitrato. O aumento no suprimento de nitrato aumentou a atividade da redutase do nitrato nas raizes e da glutamina sintetase, glutamato sintase e glutamato desidrogenase nas folhas de plantas jovens de seringueira. A reducao do nitrato parece ocorrer basicamente no sistema radicular, ja que nao se conseguiu detectar atividade da redutase do nitrato na parte aerea. Por outro lado, a atividade das enzimas de assimilacao de amonio foi significativamente mais alta nos tecidos foliares, indicando que as folhas sao os principais sitios de incorporacao de amonio em aminoacidos. Essas observacoes sugerem que a seringueira possui mecanismos para transportar o nitrogenio reduzido das raizes ate as folhas antes de sua incorporacao em aminoacidos

Aplicação de cálcio alivia parcialmente o efeito deletério da hipoxia em uma cultivar de milho selecionada para tolerância ao encharcamento.

xSuplemento. Edição dos resumos do IX Congresso Brasileiro de Fisiologia Vegetal, 2003, Atibaia, SP

Calcium partially relieves the deleterius effects of hypoxia on a maize cultivar selected for waterlogging tolerance.

Low soil oxygen concentrations due to waterlogging or transient flooding severely reduce maize production. However, genotypes with tolerance or even resistance to hypoxia develop morphological and biochemical adaptation mechanisms which may prove to be useful criteria for the selection and breeding of new improved genotypes. The objective of this work was to evaluate the effect of levels and modes of application of calcium sources on biomass yield, the contents of total soluble sugars and reduced sugars and on the activities of invertase isoforms and phosphoenolpyruvate carboxylase, in a maize variety (BRS 4154) derived from the 14th selection cycle for tolerance to transient soil flooding conditions, when cultivated under waterlogging conditions. The study was carried out in a greenhouse, utilizing 20 kg pots, filled with a lowland soil. The effects of two sources of calcium (CaCl2, 300 kg ha-1 and CaSO4, 500 and 1.500 kg ha-1) and three modes of application (applied 8 cm below surface, mixed with the whole soil volume and surface application) were tested in soils kept at field capacity and waterlogged after plants reached growth stage V6. Above ground biomass yield, the contents of total soluble sugars and reducing sugars and the activities of the neutral citosol (INC), acid vacuolar (IAV), acid cell wall invertases and phosphoenolpyruvate carboxylase were determined at the onset of flowering. Calcium application partially relieved the deleterious effect of waterlogging on biomass yield and the activities of INC, IAPC and PEPcase

Genomic characterization of pediatric B‐lymphoblastic lymphoma and B‐lymphoblastic leukemia using formalin‐fixed tissues

BackgroundRecurrent genomic changes in B‐lymphoblastic leukemia (B‐ALL) identified by genome‐wide single‐nucleotide polymorphism (SNP) microarray analysis provide important prognostic information, but gene copy number analysis of its rare lymphoma counterpart, B‐lymphoblastic lymphoma (B‐LBL), is limited by the low incidence and lack of fresh tissue for genomic testing.ProcedureWe used molecular inversion probe (MIP) technology to analyze and compare copy number alterations (CNAs) in archival formalin‐fixed paraffin‐embedded pediatric B‐LBL (n = 23) and B‐ALL (n = 55).ResultsSimilar to B‐ALL, CDKN2A/B deletions were the most common alteration identified in 6/23 (26%) B‐LBL cases. Eleven of 23 (48%) B‐LBL patients were hyperdiploid, but none showed triple trisomies (chromosomes 4, 10, and 17) characteristic of B‐ALL. IKZF1 and PAX5 deletions were observed in 13 and 17% of B‐LBL, respectively, which was similar to the reported frequency in B‐ALL. Immunoglobulin light chain lambda (IGL) locus deletions consistent with normal light chain rearrangement were observed in 5/23 (22%) B‐LBL cases, compared with only 1% in B‐ALL samples. None of the B‐LBL cases showed abnormal, isolated VPREB1 deletion adjacent to IGL locus, which we identified in 25% of B‐ALL.ConclusionsOur study demonstrates that the copy number profile of B‐LBL is distinct from B‐ALL, suggesting possible differences in pathogenesis between these closely related diseases.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/137353/1/pbc26363.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/137353/2/pbc26363_am.pd

A Murine Rp1 Missense Mutation Causes Protein Mislocalization and Slowly Progressive Photoreceptor Degeneration

Mutations in the RP1 gene can cause retinitis pigmentosa. We identified a spontaneous L66P mutation caused by two adjacent point mutations in the Rp1 gene in a colony of C57BL/6J mice. Mice homozygous for the L66P mutation exhibited slow, progressive photoreceptor degeneration throughout their lifespan. Optical coherence tomography imaging found abnormal photoreceptor reflectivity at 1 month of age. Histology found shortening and disorganization of the photoreceptor inner and outer segments and progressive thinning of the outer nuclear layer. Electroretinogram a- and b-wave amplitudes were decreased with age. Western blot analysis found that the quantity and size of the mutated retinitis pigmentosa 1 (RP1) protein were normal. However, immunohistochemistry found that the mutant Rp1 protein partially mislocalized to the transition zone of the shortened axonemes. This mutation disrupted colocalization with cytoplasmic microtubules in vitro. In conclusion, the L66P mutation in the first doublecortin domain of the Rp1 gene impairs Rp1 protein localization and function, leading to abnormalities in photoreceptor outer segment structure and progressive photoreceptor degeneration. This is the first missense mutation in Rp1 shown to cause retinal degeneration. It provides a unique, slowly progressive photoreceptor degeneration model that mirrors the slow degeneration kinetics in most patients with retinitis pigmentosa

Endoscopic repair of cerebrospinal fluid rhinorrhea: Learning from our failures

Endoscopic repair of cerebrospinal fluid (CSF) rhinorrhea is becoming a common procedure. The purpose of this study was to perform a literature analysis centering cases of treatment failure and to review our 31 cases with a 1-year minimum follow-up. An extensive search of the literature was conducted, which focused on success rate, follow-up, diagnostic techniques, graft material used, failure rate, and comments on failures. A retrospective analysis of our 31 patients was carried out, and all cases were treated with the endoscopic approach with a 1-year minimum follow-up. From the literature analysis, the median success rate at the first endoscopic attempt is 90%. Our success rate was 87.1%. Failures were analyzed. A unique protocol for CSF leak diagnosis does not exist; we suggest our diagnostic algorithm. Graft material used depends on the authors' experience, and based on this review of cases to date, did not significantly, influence the success rate. The analysis of cases of failure shows that the majority of authors omit details. More research is needed to improve prevention of failures