Localised analytic torsion and relative analytic torsion for non compact Lie groups of type I

Let $G$ be a (non compact) connected simply connected locally compact second countable Lie group, either abelian or unimodular of type I, and $\rho$ an irreducible unitary representation of $G$. Then, we define the analytic torsion of $G$ localised at the representation $\rho$. Next, let $\Gamma$ a discrete cocompact subgroup of $G$. We use the localised analytic torsion to define the relative analytic torsion of the pair $(G,\Gamma)$, and we prove that it coincides with the Lott $L^2$ analytic torsion of a covering space. We illustrate these constructions analysing in some details two examples: the abelian case, and the case $G=H$, the Heisenberg group

Perinatal Depression and Anxiety Symptoms, Parental Bonding and Dyadic Sensitivity in Mother–Baby Interactions at Three Months Post-Partum

The quality of the early parent-infant relationship is crucial for the child's optimal development, and parental sensitivity plays a key role in early interactions. The purpose of the study was to evaluate the influence of maternal perinatal depression and anxiety symptoms on dyadic sensitivity at three months post-partum, also considering a large set of maternal and infant variables. At the third trimester of pregnancy (T1) and at three months postpartum (T2), 43 primiparous women filled in a set of questionnaires evaluating symptoms of depression (CES-D) or anxiety (STAI), the woman's parental bonding experiences (PBI), alexithymia (TAS-20), maternal attachment to the baby (PAI, MPAS) and the perceived social support (MSPSS). At T2 mothers also completed a questionnaire on infant temperament and took part in the CARE-Index videotaped procedure. Dyadic sensitivity was predicted by higher maternal trait anxiety scores in pregnancy. In addition, the mother's experience of being cared for by her father in childhood was predictive of her infant's lower compulsivity, while paternal overprotection predicted higher unresponsiveness. The results highlight the influence of perinatal maternal psychological well-being and maternal childhood experiences on the quality of the dyadic relationship. The results may be useful to foster mother-child adjustment during the perinatal period

A newborn with partial pure trisomy of chromosome 7q inherited from paternal balanced translocation with congenital anomalies. a mini review

We report on a familial translocation t(3;7)(3q29::7q22) leading to pure trisomy 7q22 --> 7qter in a 21-days-old boy: 46,XY,der(3;7)(3pter--> 3q29::7q22--> 7pter). By conventional citogenetic techniques including fluorescence in situ hybridization (FISH) analysis, the patient was found to have inherited a derivative chromosome 3 from his father: 46,XY,t(3;7)(3pter--> 3q29::7q22--> 7qter;7pter--> 7q22). As a consequence, pure duplications of chromosome 7q have been classified in 4 groups on the basis of the involved region. The present case is included in group 2 which involves large duplications spanning from proximal bands to telomere duplication. In the literature, only one case with a pure duplication of the same region has been described. Despite this, the phenotype is different. Moreover, our patient shares some phenotypic features, such as wide fontanelle, retrognathia, epicathal fold, hypertelorism, pulmonary hypoventilation and early postnatal death. However, the absence of physical characterization in most of the reported cases could justify the lacking phenotype-genotype correlation in patients with partial 7q duplication. Further studies using recent molecular approaches such as array-CGH might permit a more clinically useful grouping of 7q duplications.Fil: Siewert, Susana Elfrida. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Bioquímica y Ciencias Biológicas; ArgentinaFil: Della Vedova, Maria Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaFil: Guillamondegui, M. J.. Provincia de Mendoza. Hospital Pediátrico Dr. Humberto J. Notti; ArgentinaFil: Drut, M.. Laboratorio Privado; ArgentinaFil: Brezigar A.. Provincia de San Luis. Clinic Cerhu; ArgentinaFil: Cardetti, M.. Provincia de San Luis. Clinic Cerhu; ArgentinaFil: Marsá, S.M.. Laboratorio Genes; Argentin

Approximating Clustering of Fingerprint Vectors with Missing Values

The problem of clustering fingerprint vectors is an interesting problem in Computational Biology that has been proposed in (Figureroa et al. 2004). In this paper we show some improvements in closing the gaps between the known lower bounds and upper bounds on the approximability of some variants of the biological problem. Namely we are able to prove that the problem is APX-hard even when each fingerprint contains only two unknown position. Moreover we have studied some variants of the orginal problem, and we give two 2-approximation algorithm for the IECMV and OECMV problems when the number of unknown entries for each vector is at most a constant.Comment: 13 pages, 4 figure

Review of dohan eherenfest et al. (2009) on “classification of platelet concentrates: from pure platelet-rich plasma (p-prp) to leucocyte- and platelet-rich fibrin (l-prf)”

This classic discusses the original publication of Dohan Eherenfest et al. on "Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF)", in which the authors propose four categories of platelet concentrates depending on their leukocyte and fibrin content (P-PRP, leucocyte- and platelet-rich plasma (L-PRP), pure platelet-rich fibrin (P-PRF), and L-PRF) to group a "jungle" of products in which the term platelet-rich plasma (PRP) was used indistinctly. They were able to identify common factors such as: (1) the use of anticoagulant and immediate centrifugation of the blood after its collection, (2) most preparation techniques allowed platelet concentrate preparation within an hour, (3) the centrifugation aimed to separate the blood in layers that would allow the extraction of specific fractions, and (4) the product was activated with thrombin or calcium chloride. The reviewed manuscript has been listed among the most cited PRP articles in regenerative medicine, with more than 800 citations, driving the current scientific research and clinical practice by categorizing L-PRP and P-PRP (now, leukocyte-poor PRP). The classification has also opened the door to understanding intrinsic biological mechanisms between the platelets, leukocytes, fibrin, and growth factors, later considered for studying the proliferation and differentiation of cells in different tissues affected by PRP. Since the initial classification of platelet concentrates, several other classification systems have been proposed and published in the current literature, such as the PAW, Mishra, PLRA, DEPA, MARSPILL, etc. These classifications have identified important aspects of PRP that affect the biological composition and, ultimately, the indications and outcomes. To date, there is still a lack of standardization in sample preparation, cohort heterogeneity, and incomplete reporting of sample preparation utilized, leading to a lack of clarity and challenging researchers and clinicians

High-spin states and band terminations in v 49

High-spin states in 49 V have been studied through the 28 Si(28 Si, α3p) reaction using the EUROBALL γ-ray detector array. The 49 V level scheme has been extended up to 13.1 MeV including 21 new states. Both negative and positive parity states have been interpreted in the framework of theShell Model. The 27/2− and the 31/2+ band termination states have been observed in agreement with theoretical predictions.Fil: Rodrigues Ferreira Maltez, Dario Pablo. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Área de Investigación y Aplicaciones No Nucleares. Gerencia Física (Centro Atómico Constituyentes). Proyecto Tandar; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Física; ArgentinaFil: Hojman, Daniel Leonardo. Comisión Nacional de Energía Atómica. Gerencia del Área de Investigación y Aplicaciones No Nucleares. Gerencia Física (Centro Atómico Constituyentes). Proyecto Tandar; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Lenzi, Silvia M.. Istituto Nazionale Di Fisica Nucleare.; Italia. Università di Padova; ItaliaFil: Cardona, Maria Angelica. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Área de Investigación y Aplicaciones No Nucleares. Gerencia Física (Centro Atómico Constituyentes). Proyecto Tandar; Argentina. Universidad Nacional de San Martín. Escuela de Ciencia y Tecnología; ArgentinaFil: Fernea, Enrico. Università di Padova; Italia. Istituto Nazionale Di Fisica Nucleare.; ItaliaFil: Axiotis, M.. Istituto Nazionale Di Fisica Nucleare.; ItaliaFil: Beck, C.. Université de Strasbourg; Francia. Centre National de la Recherche Scientifique; FranciaFil: Bednarczyk, P.. Polish Academy of Sciences; ArgentinaFil: Bizzetti, P. G.. Università di Padova; Italia. Istituto Nazionale Di Fisica Nucleare.; ItaliaFil: Bizzetti Sona, A. M.. Università di Padova; Italia. Istituto Nazionale Di Fisica Nucleare.; ItaliaFil: Della Vedova, F.. Università di Padova; Italia. Istituto Nazionale Di Fisica Nucleare.; ItaliaFil: Grebosz, J.. Polish Academy of Sciences; ArgentinaFil: Haas, F.. Université de Strasbourg; Francia. Centre National de la Recherche Scientifique; FranciaFil: Kmiecik, M.. Polish Academy of Sciences; ArgentinaFil: Maj, A.. Polish Academy of Sciences; ArgentinaFil: Męczyński, W.. Polish Academy of Sciences; ArgentinaFil: Napoli, D. R.. Istituto Nazionale Di Fisica Nucleare.; ItaliaFil: Nespolo, M.. Università di Padova; Italia. Istituto Nazionale Di Fisica Nucleare.; ItaliaFil: Papka, P.. Université de Strasbourg; Francia. Centre National de la Recherche Scientifique; FranciaFil: Sánchez i Zafra, A.. Université de Strasbourg; Francia. Centre National de la Recherche Scientifique; FranciaFil: Styczen, J.. Polish Academy of Sciences; ArgentinaFil: Thummerer, S.. Alfred-Wegener-Institut, Helmholtz-Zentrum für Polar- und Meeresforschung; AlemaniaFil: Ziębliński, M.. Polish Academy of Sciences; Argentin

Extraction, purification and in vitro assessment of the antioxidant and anti-inflammatory activity of policosanols from non-psychoactive Cannabis sativa L

: Policosanols (PCs) are bioactive compounds extracted from different natural waxes. In this work, the purification, characterization and assessment of the antioxidant and anti-inflammatory activity was carried out on PCs from an innovative source, i.e. a waxy material from supercritical-fluid extraction (SFE) of non-psychoactive Cannabis sativa L. (hemp) inflorescences. Starting from this material, PCs were obtained by microwave-assisted trans-esterification and hydrolysis, followed by preparative liquid chromatography under normal phase conditions. The purified product was characterized using high-performance liquid chromatography (HPLC) with an evaporative light scattering detector (ELSD). In vitro cell-free and cell-based antioxidant and anti-inflammatory assays were then performed to assess their bioactivity. HPLC-ELSED analysis of the purified mixture from hemp wax revealed C26OH and C28OH as the main compounds. In vitro assays indicated an inhibition of intracellular reactive oxygen species (ROS) production, a reduction of nuclear factor kappa B (NF-κB) activation and of the activity of the neutrophil elastase. Immunoblotting assays allowed us to hypothesize the mechanism of action of the compounds of interest, given the higher levels of MAPK-activated protein kinase 2 (MK2) and heme oxygenase-1 (HO-1) protein expression in the PC pretreated HaCaT cells. In conclusion, even if more research is needed to unveil other molecular mechanisms involved in hemp PC activity, the results of this work suggest that these compounds may have potential for use in oxinflammation processes

The Italian language postpartum specific anxiety scale [PSAS-IT]: translation, psychometric evaluation, and validation.

Introduction: While often positive, the lifecourse transition to motherhood is susceptible to the risk for developing mood disorders. Postpartum anxiety has often been overshadowed by other perinatal-specific mental health disorders, such as postpartum depression, and therefore has not been at the forefront or center of as much empirical study. This has meant there is a lack of effective and reliable tools with which to measure it, despite growing evidence suggesting its detrimental impact on mothers, their babies, wider family and social contacts, and on healthcare systems. This current study aimed to translate and validate the Postpartum Specific Anxiety Scale [PSAS] into the Italian language, and to validate the tool for its use in detecting anxiety specific to motherhood. Methods: The study (N = 457) comprised 4 stages: English-Italian translation and back-translation to obtain the Italian version [PSAS-IT]; a preliminary pilot study to adapt the PSAS to the characteristics of the Italian population; measurement invariance; and internal reliability of subscales. Results: The PSAS-IT demonstrates similar psychometric properties as the original English-language PSAS, with acceptable acceptability, construct and convergent validity, and internal consistency. Confirmatory factor analysis for multiple groups (Italy and United Kingdom) showed that the factor structure of the PSAS was valid for both groups [χ2 (2436) = 4679.481, p < 0.001, TLI = 0.969, CFI =0.972, RMSEA = 0.045, SRMR =0.064]. Discussion: The resulting findings offer a reliable measure of postpartum anxiety in Italian language up to six months after birth

Transition probabilities in the X(5) candidate 122^{122}Ba

To investigate the possible X(5) character of 122Ba, suggested by the ground state band energy pattern, the lifetimes of the lowest yrast states of 122Ba have been measured, via the Recoil Distance Doppler-Shift method. The relevant levels have been populated by using the 108Cd(16O,2n)122Ba and the 112Sn(13C,3n)122Ba reactions. The B(E2) values deduced in the present work are compared to the predictions of the X(5) model and to calculations performed in the framework of the IBA-1 and IBA-2 models