Challenges and solutions for Latin American-trained international medical graduates in psychiatry residency

Objective: Latin American-trained international medical graduates (IMGs) in psychiatry residency face multiple challenges that go beyond their medical training. These challenges call for innovative problem-solving. Although the professional development of IMGs has been discussed in the professional literature, little is written about their experiences. In this report, a group of IMGs reflect on their experiences and describe how they solved challenges. Method: Using cogenerative ethnography, four IMGs trained in Colombia, the Dominican Republic, and Mexico provided insights on their challenges and solutions while adapting to psychiatric residency training. Individual interviews, focused discussion, and written reports were analyzed using data reduction, data display, and conclusion-drawing techniques. Results: We illustrate the challenges of IMG training in psychiatry using their reflections and stories. We categorize these challenges into three domains: immigration and acculturation, social adjustment, and medical training. Quotes were selected to illustrate IMGs’ challenges and coping strategies. Conclusion: Some of the combined cultural, social, and academic challenges of Latin American-trained IMGs in psychiatry residency are described. Recognizing and planning for the personal challenges of IMGs in psychiatry can enhance the transition into psychiatric training. Ultimately, improvements in IMG training converts into improved healthcare for all patients

The correlation between leader–member exchange and organisational commitment among spanish registered nurses: The moderating role of sex and hospital size

The role of the supervisor in hospitals is to oversee and encourage the active work participation of registered nurses. In this context, leadership should be focused on the creation of a positive environment for the generation of high-quality care and the development of attitudes that have a beneficial influence on the work of the registered nurse. The aims of this study have been: (i) To verify if the quality of the supervisor–nurse interpersonal relationship was correlated with organisational commitment; (ii) to establish if the correlation could be moderated by empowerment, perceived organisational support, and leader–leader exchange. A cross-sectional survey with self-report questionnaires was performed. A total of 2541 registered nurses from nine public hospitals participated in the study. They completed scales measuring leader–member exchange, commitment, empowerment, perceived organisational support, and leader–leader exchange. There was a positive correlation between the quality of the leader–member exchange and commitment. Leader–leader exchange has a moderating effect on this relationship. The moderating effects of empowerment, perceived organisational support, and leader–member exchange on the supervisor–nurse interpersonal relationship and the nurse’s organisational commitment are influenced by sex and/or hospital size. Organisations should design supervisor training strategies aimed at establishing high-quality supervisor–nurse interpersonal relationships

Challenges and solutions for Latin American-trained international medical graduates in psychiatry residency

Objective: Latin American-trained international medical graduates (IMGs) in psychiatry residency face multiple challenges that go beyond their medical training. These challenges call for innovative problem-solving. Although the professional development of IMGs has been discussed in the professional literature, little is written about their experiences. In this report, a group of IMGs reflect on their experiences and describe how they solved challenges. Method: Using cogenerative ethnography, four IMGs trained in Colombia, the Dominican Republic, and Mexico provided insights on their challenges and solutions while adapting to psychiatric residency training. Individual interviews, focused discussion, and written reports were analyzed using data reduction, data display, and conclusion-drawing techniques. Results: We illustrate the challenges of IMG training in psychiatry using their reflections and stories. We categorize these challenges into three domains: immigration and acculturation, social adjustment, and medical training. Quotes were selected to illustrate IMGs’ challenges and coping strategies. Conclusion: Some of the combined cultural, social, and academic challenges of Latin American-trained IMGs in psychiatry residency are described. Recognizing and planning for the personal challenges of IMGs in psychiatry can enhance the transition into psychiatric training. Ultimately, improvements in IMG training converts into improved healthcare for all patients

K-Factores en nubes bicromáticas

Consideramos una colección de puntos bicromática y nos preguntamos cuántos puntos adicionales son necesarios considerar para asegurar la existencia de un k {factor. Dos tipos de puntos adicionales serán tratados: puntos de Steiner y puntos blancos (con posición prefijada pero no así su color

NDP-MSH reduces oxidative damage induced by palmitic acid in primary astrocytes

Recent findings relate obesity to inflammation in key hypothalamic areas for body weight control. Hypothalamic inflammation has also been related to oxidative stress. Palmitic acid (PA) is the most abundant free fatty acid found in food, and in vitro studies indicate that it triggers a pro-inflammatory response in the brain. Melanocortins are neuropeptides with proven anti-inflammatory and neuroprotective action mediated by melanocortin receptor 4 (MC4R), but little is known about the effect of melanocortins on oxidative stress. The aim of this study was to investigate whether melanocortins could alleviate oxidative stress induced by a high fat diet (HFD) model. We found that NDP-MSH treatment decreased PA-induced reactive oxygen species production in astrocytes, an effect blocked by the MC4R inhibitor JKC363. NDP-MSH abolished nuclear translocation of Nrf2 induced by PA and blocked the inhibitory effect of PA on superoxide dismutase (SOD) activity and glutathione levels while it also per se increased activity of SOD and γ-glutamate cysteine ligase (γ-GCL) antioxidant enzymes. However, HFD reduced hypothalamic MC4R and brain derived neurotrophic factor mRNA levels, thereby preventing the neuroprotective mechanism induced by melanocortins.Fil: Ramírez, Delia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; ArgentinaFil: Saba, Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; ArgentinaFil: Turati, Juan. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; ArgentinaFil: Carniglia, Lila. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; ArgentinaFil: Imsen, Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; ArgentinaFil: Mohn, Claudia Ester. Universidad de Buenos Aires. Facultad de Odontología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; ArgentinaFil: Scimonelli, Teresa Nieves. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Farmacología Experimental de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Farmacología Experimental de Córdoba; ArgentinaFil: Durand, Daniela Elizabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; ArgentinaFil: Caruso, Carla Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; ArgentinaFil: Lasaga, Mercedes Isabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones Biomédicas. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Biomédicas; Argentin

Coordination of microtubule and microfilament dynamics by Drosophila Rho1, Spire, and Cappuccino

The actin nucleation factors Spire and Cappuccino regulate the onset of ooplasmic streaming in Drosophila1-5. Although this streaming event is microtubule-based, actin assembly is required for its timing. It is not understood how the interaction of microtubules and microfilaments is mediated in this context. Here we demonstrate that Cappuccino and Spire have microtubule and microfilament crosslinking activity. The spire locus encodes several distinct protein isoforms (SpireA, SpireC, and SpireD). SpireD was recently shown to nucleate actin, but the activity of the other isoforms has not been addressed. We find that SpireD does not have crosslinking activity, while SpireC is a potent crosslinker. We show that SpireD binds to Cappuccino and inhibits Factin/ microtubule crosslinking, and activated Rho1 abolishes this inhibition, establishing a mechanistic basis for the regulation of Capu and Spire activity. We propose that Rho1, cappuccino and spire are elements of a conserved developmental cassette that is capable of directly mediating crosstalk between microtubules and microfilaments

Cultivating consciousness with science

El proyecto Cultivando Consciencia con Ciencia propone el establecimiento de una granja agroecológica en la comunidad educativa de la Escuela N° 263 Provincia de Catamarca, del Barrio El Molino de la Ciudad de Belén, Departamento Belén, Provincia de Catamarca. Avances en su implementación demostraron oportunidades de aprendizaje combinando contenidos de primer y segundo ciclo de la educación formal con la producción de alimentos en una granja agroecológica, la formación en valores ecológicos y el trabajo en equipo. Para los actores involucrados en el proyecto, el espacio que se construye permite vivenciar valiosas experiencias. Docentes investigadores junto a estudiantes avanzados de Agronomía y becarios intervienen con acciones de capacitación teórico-prácticas para la elaboración de secuencias didácticas que estimule el aprendizaje científico basado en la indagación, permitiendo al capacitando explorar, descubrir y desarrollar nuevos conocimientos aplicados a necesidades concretas de su contexto. En estas instancias, la difusión de información científico técnica crea condiciones que asegura que se enseñe lo que se necesita, que lo enseñado se aprenda y que lo aprendido sea transferido a otros problemas.The project “Cultivating consciousness with science” proposes locating an agroecological farm in the educational community of School N° 263 Province of Catamarca, District El Molino, Belén Department, Province of Catamarca. Developments in its implementation proved learning opportunities by combining contents of first and second cycle of formal education with food production in an agroecological farm, as well as training in ecology values and teamwork. For the actors participating in the project, the space built provides valuable experiences. Teachers-researchers together with advanced agronomy students and scholarships play an important role through theoretical-practical training actions for the elaboration of didactic sequences that stimulate scientific learning based on research. This allows students to explore, discover and develop new knowledge applied to their contextual specific needs. In this context, technical scientific knowledge dissemination creates conditions to ensure the teaching of what is needed by students. Also, to promote learning and knowledge and their transfer to other problems.Fil: Denett, Gabriel Omar. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Catamarca. Facultad de Ciencias Agrarias; ArgentinaFil: Barros, Lucas Ariel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Catamarca. Facultad de Ciencias Agrarias; ArgentinaFil: Denett, Yanina Lorena. Universidad Nacional de Catamarca. Facultad de Ciencias Agrarias; ArgentinaFil: Espeche, Lucas Javier. Universidad Nacional de Catamarca. Facultad de Ciencias Agrarias; ArgentinaFil: Campos Olmos, María Virginia. Universidad Nacional de Catamarca. Facultad de Ciencias Agrarias; ArgentinaFil: Lencina, Sibila Ivonne. Universidad Nacional de Catamarca. Facultad de Ciencias Agrarias; ArgentinaFil: Soria, Rosana R.. Universidad Nacional de Catamarca. Facultad de Ciencias Agrarias; ArgentinaFil: Mohamed, Carolina B.. Universidad Nacional de Catamarca. Facultad de Ciencias Agrarias; ArgentinaFil: Salas, Monica Delia. Universidad Nacional de Catamarca. Facultad de Ciencias Agrarias; ArgentinaFil: Cisterna Fernandez, Maria Ines. Universidad Nacional de Catamarca. Facultad de Tecnología y Cs.aplicadas. Departamento de Formación Basica; ArgentinaFil: Ortiz, Erlinda del Valle. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Catamarca. Facultad de Tecnología y Ciencias Aplicadas; Argentina. Universidad Nacional de Catamarca. Facultad de Tecnología y Ciencias Aplicadas. Instituto de Monitoreo y Control de la Degradación Geoambiental; ArgentinaFil: Comelli, Nieves Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigaciones y Transferencia de Catamarca. Universidad Nacional de Catamarca. Centro de Investigaciones y Transferencia de Catamarca; Argentina. Universidad Nacional de Catamarca. Facultad de Ciencias Agrarias; Argentin

Experiències entrecreuades a Santa Eugènia del Congost

Rastres de memòria no escrita. D’experiències entrecreuades a Santa Eugènia del Congost... és el primer d’una sèrie de quaderns de treball amb mostres de material visual recollit en el marc del projecte artístic i didàctic Experiències entrecreuades a Santa Eugènia del Congost, desenvolupat en el context de l’antiga font i safareigs de Santa Eugènia del Congost –situats prop de l’autovia C-17, el riu Congost i de l’Ajuntament de Tagamanent–. Des del curs acadèmic 2016-2017, el Grup d’Innovació Docent Consolidat de la Universitat de Barcelona ATESI (Art, Territori, Estratègia Docent, Sostenibilitat i Intervenció Social – GINDC-UB/162) promou accions –instal·lacions artístiques efímeres, performance, tallers oberts, exposicions i actes...– per tal de «reviure» de forma física i conceptual aquests espais en desús per a la població, tot fent èmfasi en la recuperació de la seva memòria històrica, i amb una metodologia que busca integrar l’actuació conjunta d’administracions, figures expertes, centres educatius i ciutadanes. Aquestes accions, ideològicament posicionades, parteixen del treball en règim d’Aprenentatge Servei (ApS), una metodologia docent que implica l’assoliment de competències educatives en la realització d’activitats que tenen un retorn directe en la comunitat. En aquesta línia, les actuacions dutes a terme que es mostren en aquest quadern han tingut la participació d’alumnat del Grau en Belles Arts de la Universitat de Barcelona, de l’Escola Sagrats Cors de Centelles, de l’Escola d’Art i Superior de Disseny de Vic i d’ex-alumnes del mateix centre (EXARTVIC), coordinat per professorat dels diferents àmbits i amb la participació del Grup ApS(UB)

Global Retinoblastoma Presentation and Analysis by National Income Level.

Importance: Early diagnosis of retinoblastoma, the most common intraocular cancer, can save both a child's life and vision. However, anecdotal evidence suggests that many children across the world are diagnosed late. To our knowledge, the clinical presentation of retinoblastoma has never been assessed on a global scale. Objectives: To report the retinoblastoma stage at diagnosis in patients across the world during a single year, to investigate associations between clinical variables and national income level, and to investigate risk factors for advanced disease at diagnosis. Design, Setting, and Participants: A total of 278 retinoblastoma treatment centers were recruited from June 2017 through December 2018 to participate in a cross-sectional analysis of treatment-naive patients with retinoblastoma who were diagnosed in 2017. Main Outcomes and Measures: Age at presentation, proportion of familial history of retinoblastoma, and tumor stage and metastasis. Results: The cohort included 4351 new patients from 153 countries; the median age at diagnosis was 30.5 (interquartile range, 18.3-45.9) months, and 1976 patients (45.4%) were female. Most patients (n = 3685 [84.7%]) were from low- and middle-income countries (LMICs). Globally, the most common indication for referral was leukocoria (n = 2638 [62.8%]), followed by strabismus (n = 429 [10.2%]) and proptosis (n = 309 [7.4%]). Patients from high-income countries (HICs) were diagnosed at a median age of 14.1 months, with 656 of 666 (98.5%) patients having intraocular retinoblastoma and 2 (0.3%) having metastasis. Patients from low-income countries were diagnosed at a median age of 30.5 months, with 256 of 521 (49.1%) having extraocular retinoblastoma and 94 of 498 (18.9%) having metastasis. Lower national income level was associated with older presentation age, higher proportion of locally advanced disease and distant metastasis, and smaller proportion of familial history of retinoblastoma. Advanced disease at diagnosis was more common in LMICs even after adjusting for age (odds ratio for low-income countries vs upper-middle-income countries and HICs, 17.92 [95% CI, 12.94-24.80], and for lower-middle-income countries vs upper-middle-income countries and HICs, 5.74 [95% CI, 4.30-7.68]). Conclusions and Relevance: This study is estimated to have included more than half of all new retinoblastoma cases worldwide in 2017. Children from LMICs, where the main global retinoblastoma burden lies, presented at an older age with more advanced disease and demonstrated a smaller proportion of familial history of retinoblastoma, likely because many do not reach a childbearing age. Given that retinoblastoma is curable, these data are concerning and mandate intervention at national and international levels. Further studies are needed to investigate factors, other than age at presentation, that may be associated with advanced disease in LMICs