Misrecollection prevents older adults from benefitting from semantic relatedness of the memoranda in associative memory.

Memory for episodic associations declines in aging, ostensibly due to decreased recollection abilities. Accordingly, associative unitization - the encoding of associated items as one integrated entity - may potentially attenuate age-related associative deficits by enabling familiarity-based retrieval, which is relatively preserved in aging. To test this hypothesis, we induced bottom-up unitization by manipulating semantic relatedness between memoranda. Twenty-four young and 24 older adults studied pairs of object pictures that were either semantically related or unrelated. Participants subsequently discriminated between intact, recombined and new pairs. We found that semantic relatedness increased the contributions of both familiarity and recollection in young adults, but did not improve older adults' performance. Instead, they showed associative deficits, driven by increased recollection-based false recognition. This may reflect a "misrecollection" phenomenon, in which older adults make more false alarms to recombined pairs with particularly high confidence, due to poorer retrieval monitoring regarding semantically-related associative probes

Prognostic value of the ratio between prothesis area and indexed annulus area measured by multiSlice-CT for transcatheter aortic valve implantation procedures

Background Postprocedural aortic regurgitations following transcatheter aortic valve implantation (TAVI) procedures remain an is- sue. Benefit of oversizing strategies to prevent them isn’t well established. We compared different level of oversizing in our cohort of con- secutive patients to address if severe oversizing compared to normal sizing had an impact on post-procedural outcomes. Methods From January 2010 to August 2013, consecutive patients were referred for TAVI with preoperative Multislice-CT (MSCT) and the procedures were achieved using Edwards Sapien® or Corevalve devices®. Retrospectively, according to pre-procedural MSCT and the valve size, pa- tients were classified into three groups: normal, moderate and severe oversizing; depending on the ratio between the prosthesis area and the annulus area indexed and measured on MSCT. Main endpoint was mid-term mortality and secondary endpoints were the Valve Academic Research Consortium (VARC-2) endpoints. Results Two hundred and sixty eight patients had a MSCT and underwent TAVI procedure, with mainly Corevalve®. While all-cause and cardiovascular mortality rates were similar in all groups, post-procedural new pacemaker (PM) implantation rate was significantly higher in the severe oversizing group (P = 0.03), while we observed more in-hospital congestive heart-failure (P = 0.02) in the normal sizing group. There was a trend toward more moderate to severe aortic regurgitation (AR) in the normal sizing group (P = 0.07). Conclusions Despite a higher rate of PM implantation, oversizing based on this ratio reduces aortic leak with lower rates of post-procedural complications and a similar mid-term survival

Correcting for static shift of magnetotelluric data with airborne electromagnetic measurements: a case study from Rathlin Basin, Northern Ireland

Galvanic distortions of magnetotelluric (MT) data, such as the static-shift effect, are a known problem that can lead to incorrect estimation of resistivities and erroneous modelling of geometries with resulting misinterpretation of subsurface electrical resistivity structure. A wide variety of approaches have been proposed to account for these galvanic distortions, some depending on the target area, with varying degrees of success. The natural laboratory for our study is a hydraulically permeable volume of conductive sediment at depth, the internal resistivity structure of which can be used to estimate reservoir viability for geothermal purposes; however, static-shift correction is required in order to ensure robust and precise modelling accuracy.We present here a possible method to employ frequency–domain electromagnetic data in order to correct static-shift effects, illustrated by a case study from Northern Ireland. In our survey area, airborne frequency domain electromagnetic (FDEM) data are regionally available with high spatial density. The spatial distributions of the derived static-shift corrections are analysed and applied to the uncorrected MT data prior to inversion. Two comparative inversion models are derived, one with and one without static-shift corrections, with instructive results. As expected from the one-dimensional analogy of static-shift correction, at shallow model depths, where the structure is controlled by a single local MT site, the correction of static-shift effects leads to vertical scaling of resistivity–thickness products in the model, with the corrected model showing improved correlation to existing borehole wireline resistivity data. In turn, as these vertical scalings are effectively independent of adjacent sites, lateral resistivity distributions are also affected, with up to half a decade of resistivity variation between the models estimated at depths down to 2000 m. Simple estimation of differences in bulk porosity, derived using Archie's Law, between the two models reinforces our conclusion that the suborder of magnitude resistivity contrasts induced by the correction of static shifts correspond to similar contrasts in estimated porosities, and hence, for purposes of reservoir investigation or similar cases requiring accurate absolute resistivity estimates, galvanic distortion correction, especially static-shift correction, is essential

Spectral Line-by-Line Pulse Shaping of an On-Chip Microresonator Frequency Comb

We report, for the first time to the best of our knowledge, spectral phase characterization and line-by-line pulse shaping of an optical frequency comb generated by nonlinear wave mixing in a microring resonator. Through programmable pulse shaping the comb is compressed into a train of near-transform-limited pulses of \approx 300 fs duration (intensity full width half maximum) at 595 GHz repetition rate. An additional, simple example of optical arbitrary waveform generation is presented. The ability to characterize and then stably compress the frequency comb provides new data on the stability of the spectral phase and suggests that random relative frequency shifts due to uncorrelated variations of frequency dependent phase are at or below the 100 microHertz level.Comment: 18 pages, 4 figure

Towards a fully consistent Milky Way disc model: Part 1 The local model based on kinematic and photometric data

We present a fully consistent evolutionary disc model of the solar cylinder. The model is based on a sequence of stellar sub-populations described by the star formation history (SFR) and the dynamical heating law (given by the age-velocity dispersion relation AVR). The combination of kinematic data from Hipparcos and the finite lifetimes of main sequence (MS) stars enables us to determine the detailed vertical disc structure independent of individual stellar ages and only weakly dependent on the IMF. The disc parameters are determined by applying a sophisticated best fit algorithm to the MS star velocity distribution functions in magnitude bins. We find that the AVR is well constrained by the local kinematics, whereas for the SFR the allowed range is larger. A simple chemical enrichment model is included in order to fit the local metallicity distribution of G dwarfs. In our favoured model A the power law index of the AVR is 0.375 with a minimum and maximum velocity dispersion of 5.1 km/s and 25.0 km/s, respectively. The SFR shows a maximum 10 Gyr ago and declines by a factor of four to the present day value of 1.5 M_sun/pc^2/Gyr. A best fit of the IMF leads to power-law indices of -1.46 below and -4.16 above 1.72 M_sun avoiding a kink at 1 M_sun. An isothermal thick disc component with local density of ~6% of the stellar density is included. A thick disc containing more than 10% of local stellar mass is inconsistent with the local kinematics of K and M dwarfs.Comment: 20 pages, 18 figs., accepted by MNRA

Dust-enshrouded Asymptotic Giant Branch Stars in the Solar Neighbourhood

A study is made of a sample of 58 dust-enshrouded Asymptotic Giant Branch (AGB) stars (including 2 possible post AGB stars), of which 27 are carbon-rich and 31 are oxygen-rich. These objects were originally identified by Jura & Kleinmann as nearby (within about 1 kpc of the sun) AGB stars with high mass-loss rates, greater than 1E-6 solar masses per year. Ground-based near-infrared photometry, data obtained by IRAS and kinematic data from the literature are combined to investigate the properties of these stars. The light amplitude in the near-infrared is found to be correlated with period, and this amplitude decreases with increasing wavelength. Statistical tests show that there is no reason to suspect any difference in the period distributions of the carbon- and oxygen-rich stars for periods less than 1000 days, and no carbon-rich star has a period longer than 1000 days. The colours are consistent with those of cool stars with evolved circumstellar dust-shells. Luminosities and distances are estimated using a period-luminosity relation. Mass-loss rates, estimated from the 60 micron fluxes, show a correlation with pulsation period and is tightly correlated with the K-[12] colour. The kinematics and scale-height of the sample shows that the sources with periods less than 1000 days must have low mass main-sequence progenitors. It is argued that the three oxygen-rich stars with periods over 1000 days probably had intermediate mass main-sequence progenitors with remaining stars having an average progenitor mass of about 1.3 solar masses. The average lifetime of stars in this phase is estimated to be about 4.0E4 years, indicating they will undergo at most one more thermal pulse before leaving the AGB.Comment: 27 pages, 20 figures, accepted for MNRA

Update on Endoscopic Management of Main Pancreatic Duct Stones in Chronic Calcific Pancreatitis

Pancreatic duct stones are a common complication during the natural course of chronic pancreatitis and often contribute to additional pain and pancreatitis. Abdominal pain, one of the major symptoms of chronic pancreatitis, is believed to be caused in part by obstruction of the pancreatic duct system (by stones or strictures) resulting in increasing intraductal pressure and parenchymal ischemia. Pancreatic stones can be managed by surgery, endoscopy, or extracorporeal shock wave lithotripsy. In this review, updated management of pancreatic duct stones is discussed

Acceleration of generalized hypergeometric functions through precise remainder asymptotics

We express the asymptotics of the remainders of the partial sums {s_n} of the generalized hypergeometric function q+1_F_q through an inverse power series z^n n^l \sum_k c_k/n^k, where the exponent l and the asymptotic coefficients {c_k} may be recursively computed to any desired order from the hypergeometric parameters and argument. From this we derive a new series acceleration technique that can be applied to any such function, even with complex parameters and at the branch point z=1. For moderate parameters (up to approximately ten) a C implementation at fixed precision is very effective at computing these functions; for larger parameters an implementation in higher than machine precision would be needed. Even for larger parameters, however, our C implementation is able to correctly determine whether or not it has converged; and when it converges, its estimate of its error is accurate.Comment: 36 pages, 6 figures, LaTeX2e. Fixed sign error in Eq. (2.28), added several references, added comparison to other methods, and added discussion of recursion stabilit