Gamma-ray observations of Cygnus X-1 above 100 MeV in the hard and soft states

We present the results of multi-year gamma-ray observations by the AGILE satellite of the black hole binary system Cygnus X-1. In a previous investigation we focused on gamma-ray observations of Cygnus X-1 in the hard state during the period mid-2007/2009. Here we present the results of the gamma-ray monitoring of Cygnus X-1 during the period 2010/mid-2012 carried out for which includes a remarkably prolonged `soft state' phase (June 2010 -- May 2011). Previous 1--10 MeV observations of Cyg X-1 in this state hinted at a possible existence of a non-thermal particle component with substantial modifications of the Comptonized emission from the inner accretion disk. Our AGILE data, averaged over the mid-2010/mid-2011 soft state of Cygnus X-1, provide a significant upper limit for gamma-ray emission above 100 MeV of F_soft < 20 x 10^{-8} ph/cm^2/s, excluding the existence of prominent non-thermal emission above 100 MeV during the soft state of Cygnus X-1. We discuss theoretical implications of our findings in the context of high-energy emission models of black hole accretion. We also discuss possible gamma-ray flares detected by AGILE. In addition to a previously reported episode observed by AGILE in October 2009 during the hard state, we report a weak but important candidate for enhanced emission which occurred at the end of June 2010 (2010-06-30 10:00 - 2010-07-02 10:00 UT) exactly in coincidence with a hard-to-soft state transition and before an anomalous radio flare. An appendix summarizes all previous high-energy observations and possible detections of Cygnus X-1 above 1 MeV.Comment: 16 pages, 12 figures, 1 table, accepted for publication in Ap

Implementación de un servicio de terminologías médicas en una organización privada de salud

a Codificación diagnóstica de las consultas ambulatorias y de internación, es necesaria para elaborar informes estadísticos, para mejorar el registro médico electrónico y para mejorar la calidad de la atención médica. Describiremos los avances que logramos en la definición, clasificación, organización e implementación de un Servicio de Terminología basado en Ontologías, destinado a la Codificación Asistencial.Sociedad Argentina de Informática e Investigación Operativ

Implementación de receta digital en Swiss Medical, Argentina

La prescripción de un fármaco es un acto médico y administrativo. La prescripción electrónica genera menor riesgo de errores de legibilidad en la dispensación, administración de medicamentos, y permitiendo utilizar sistemas de soporte a toma de decisiones. Asimismo, evitan problemas de facturación y posibles fraudes. En marzo de 2016 Swiss Medical y DXC.technology se implementó la Historia Clínica Electrónica, donde se puede acceder al historial del paciente y contar con sistemas de alertas de duplicidad de principio activo y dosis máxima. En agosto de 2018 se inició el proyecto de telemedicina y receta digital, con atención a pacientes pediátricos y adultos afiliados. En la cual se genera la receta por nombre genérico (Ley 25.649), con firma digital (Ley 25.506), enviando la receta y las indicaciones médicas al paciente, para que accedan a cualquier farmacia de la red de Farmalink para adquirir el fármaco prescrito.Sociedad Argentina de Informática e Investigación Operativ

AGILE detection of delayed gamma-ray emission from GRB 080514B

GRB 080514B is the first gamma ray burst (GRB), since the time of EGRET, for which individual photons of energy above several tens of MeV have been detected with a pair-conversion tracker telescope. This burst was discovered with the Italian AGILE gamma-ray satellite. The GRB was localized with a cooperation by AGILE and the interplanetary network (IPN). The gamma-ray imager (GRID) estimate of the position, obtained before the SuperAGILE-IPN localization, is found to be consistent with the burst position. The hard X-ray emission observed by SuperAGILE lasted about 7 s, while there is evidence that the emission above 30 MeV extends for a longer duration (at least ~13 s). Similar behavior was seen in the past from a few other GRBs observed with EGRET. However, the latter measurements were affected, during the brightest phases, by instrumental dead time effects, resulting in only lower limits to the burst intensity. Thanks to the small dead time of the AGILE/GRID we could assess that in the case of GRB 080514B the gamma-ray to X-ray flux ratio changes significantly between the prompt and extended emission phase.Comment: A&A letters, in pres

Neutral pion emission from accelerated protons in the supernova remnant W44

We present the AGILE gamma-ray observations in the energy range 50 MeV - 10 GeV of the supernova remnant (SNR) W44, one of the most interesting systems for studying cosmic-ray production. W44 is an intermediate-age SNR (20, 000 years) and its ejecta expand in a dense medium as shown by a prominent radio shell, nearby molecular clouds, and bright [SII] emitting regions. We extend our gamma-ray analysis to energies substantially lower than previous measurements which could not conclusively establish the nature of the radiation. We find that gamma-ray emission matches remarkably well both the position and shape of the inner SNR shocked plasma. Furthermore, the gamma-ray spectrum shows a prominent peak near 1 GeV with a clear decrement at energies below a few hundreds of MeV as expected from neutral pion decay. Here we demonstrate that: (1) hadron-dominated models are consistent with all W44 multiwavelength constraints derived from radio, optical, X-ray, and gamma-ray observations; (2) ad hoc lepton-dominated models fail to explain simultaneously the well-constrained gamma-ray and radio spectra, and require a circumstellar density much larger than the value derived from observations; (3) the hadron energy spectrum is well described by a power-law (with index s = 3.0 \pm 0.1) and a low-energy cut-off at Ec = 6 \pm 1 GeV. Direct evidence for pion emission is then established in an SNR for the first time.Comment: accepted for publication on ApJ

Episodic Transient Gamma-Ray Emission from the Microquasar Cygnus X-1

Cygnus X-1 is the archetypal black hole (BH) binary system in our Galaxy. We report the main results of an extensive search for transient gamma-ray emission from Cygnus X-1 carried out in the energy range 100 MeV - 3 GeV by the AGILE satellite, during the period 2007 July - 2009 October. The total exposure time is about 300 days, during which the source was in the "hard" X-ray spectral state. We divided the observing intervals in 2 or 4 week periods, and searched for transient and persistent emission. We report an episode of significant transient gamma-ray emission detected on 2009, October 16 in a position compatible with Cygnus X-1 optical position. This episode, occurred during a hard spectral state of Cygnus X-1, shows that a 1-2 day time variable emission above 100 MeV can be produced during hard spectral states, having important theoretical implications for current Comptonization models for Cygnus X-1 and other microquasars. Except for this one short timescale episode, no significant gamma-ray emission was detected by AGILE. By integrating all available data we obtain a 2$\sigma$ upper limit for the total integrated flux of $F_{\gamma,U.L.} = 3 \times 10^{-8} \rm ph cm^{-2} s^{-1}$ in the energy range 100 MeV - 3 GeV. We then clearly establish the existence of a spectral cutoff in the energy range 1-100 MeV that applies to the typical hard state outside the flaring period and that confirms the historically known spectral cutoff above 1 MeV.Comment: Accepted for publication by ApJ on the 9th of Feb 2010, 5 pages, 3 figure

The flaring blazars of the first 1.5 years of the AGILE mission

We report the AGILE gamma-ray observations and the results of the multiwavelength campaigns on seven flaring blazars detected by the mission: During two multiwavelength campaigns, we observed gamma-ray activity from two Flat Spectrum Radio Quasars of the Virgo region, e.g. 3C 279 and 3C 273 (the latter being the first extragalactic source simultaneously observed with the gamma-ray telescope and the hard X ray imager of the mission). Due to the large FOV of the AGILE/GRID instrument, we achieved an almost continuous coverage of the FSRQ 3C 454.3. The source showed flux above 10E-6 photons/cm2/s (E > 100 MeV) and showed day by day variability during all the AGILE observing periods. In the EGRET era, the source was found in high gamma-ray activity only once. An other blazar, PKS 1510-089 was frequently found in high gamma-ray activity. S5 0716+71, an intermediate BL Lac object, exhibited a very high gamma-ray activity and fast gamma-ray variability during a period of intense optical activity. We observed high gamma-ray activity from W Comae, a BL Lac object, and Mrk 421, an high energy peaked BL Lac object. For this source, a multiwavelength campaign from optical to TeV has been performed

Direct Evidence for Hadronic Cosmic-Ray Acceleration in the Supernova Renmant IC 443

The Supernova Remnant (SNR) IC 443 is an intermediate-age remnant well known for its radio, optical, X-ray and gamma-ray energy emissions. In this Letter we study the gamma-ray emission above 100 MeV from IC 443 as obtained by the AGILE satellite. A distinct pattern of diffuse emission in the energy range 100 MeV-3 GeV is detected across the SNR with its prominent maximum (source "A") localized in the Northeastern shell with a flux F = (47 \pm 10) 10^{-8} photons cm^{-2} s^{-1} above 100 MeV. This location is the site of the strongest shock interaction between the SNR blast wave and the dense circumstellar medium. Source "A" is not coincident with the TeV source located 0.4 degree away and associated with a dense molecular cloud complex in the SNR central region. From our observations, and from the lack of detectable diffuse TeV emission from its Northeastern rim, we demonstrate that electrons cannot be the main emitters of gamma-rays in the range 0.1-10 GeV at the site of the strongest SNR shock. The intensity, spectral characteristics, and location of the most prominent gamma-ray emission together with the absence of co-spatial detectable TeV emission are consistent only with a hadronic model of cosmic-ray acceleration in the SNR. A high-density molecular cloud (cloud "E") provides a remarkable "target" for nucleonic interactions of accelerated hadrons: our results show enhanced gamma-ray production near the molecular cloud/shocked shell interaction site. IC 443 provides the first unambiguous evidence of cosmic-ray acceleration by SNRs.Comment: 5 pages, 2 figures; accepted by ApJLetters on Jan 21, 201

Calibration of AGILE-GRID with In-Flight Data and Monte Carlo Simulations

Context: AGILE is a gamma-ray astrophysics mission which has been in orbit since 23 April 2007 and continues to operate reliably. The gamma-ray detector, AGILE-GRID, has observed Galactic and extragalactic sources, many of which were collected in the first AGILE Catalog. Aims: We present the calibration of the AGILE-GRID using in-flight data and Monte Carlo simulations, producing Instrument Response Functions (IRFs) for the effective area A_eff), Energy Dispersion Probability (EDP), and Point Spread Function (PSF), each as a function of incident direction in instrument coordinates and energy. Methods: We performed Monte Carlo simulations at different gamma-ray energies and incident angles, including background rejection filters and Kalman filter-based gamma-ray reconstruction. Long integrations of in-flight observations of the Vela, Crab and Geminga sources in broad and narrow energy bands were used to validate and improve the accuracy of the instrument response functions. Results: The weighted average PSFs as a function of spectra correspond well to the data for all sources and energy bands. Conclusions: Changes in the interpolation of the PSF from Monte Carlo data and in the procedure for construction of the energy-weighted effective areas have improved the correspondence between predicted and observed fluxes and spectra of celestial calibration sources, reducing false positives and obviating the need for post-hoc energy-dependent scaling factors. The new IRFs have been publicly available from the Agile Science Data Centre since November 25, 2011, while the changes in the analysis software will be distributed in an upcoming release