A REGULAÇÃO ASSISTENCIAL NO SUS SOB A LENTE DA TEORIA DA ESTRUTURAÇÃO

This is a review article, which sought to characterize Health Care Regulation within the SUS as a social practice, considering its prerogative of integrating care points in the Health Care Network. In the context of structural complexities of SUS, implemented daily in a scenario of socioeconomic inequalities such as Brazil, regulatory action, based predominantly on normative control, has contributed to generate barriers to access to health services, contrary to its purpose of integrating points of care. It is argued that studying health care regulation and its network integration capacity, based on Antony Giddens' theory of structuring, allows a broader analysis of this phenomenon.Este es un artículo de revisión, que buscaba caracterizar la Regulación de la Atención Médica dentro del SUS como una práctica social, considerando su prerrogativa de integrar los puntos de atención en la Red de Atención Médica. En el contexto de las complejidades estructurales del SUS, implementado diariamente en un escenario de desigualdades socioeconómicas como Brasil, la acción reguladora, basada predominantemente en el control normativo, ha contribuido a generar barreras para el acceso a los servicios de salud, en contra de su propósito de integrar puntos de atención. Se argumenta que estudiar la regulación de la atención médica y su capacidad de integración de redes, basada en la teoría de estructuración de Antony Giddens, permite un análisis más amplio de este fenómeno.Trata-se de um artigo de revisão, por meio do qual buscou-se caracterizar a Regulação Assistencial no âmbito do SUS como uma prática social, considerando sua prerrogativa de integração dos pontos assistenciais na Rede de Atenção à Saúde. No contexto de complexidades estruturais do SUS, implementado cotidianamente num cenário de desigualdades socioeconômicas como o brasileiro, a ação regulatória, fundamentada predominantemente no controle normativo, tem contribuído para gerar barreiras de acesso aos serviços de saúde, contraditoriamente ao seu propósito de integrar os pontos de atenção. Argumenta-se que estudar a regulação assistencial e sua capacidade de integração da rede, fundamentados na teoria da estruturação de Antony Giddens, permite uma análise ampliada deste fenômeno.DOI: 10.53706/gep.v.21.685

The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability

Chromobacterium violaceum is one of millions of species of free-living microorganisms that populate the soil and water in the extant areas of tropical biodiversity around the world. Its complete genome sequence reveals (i) extensive alternative pathways for energy generation, (ii) ≈500 ORFs for transport-related proteins, (iii) complex and extensive systems for stress adaptation and motility, and (iv) wide-spread utilization of quorum sensing for control of inducible systems, all of which underpin the versatility and adaptability of the organism. The genome also contains extensive but incomplete arrays of ORFs coding for proteins associated with mammalian pathogenicity, possibly involved in the occasional but often fatal cases of human C. violaceum infection. There is, in addition, a series of previously unknown but important enzymes and secondary metabolites including paraquat-inducible proteins, drug and heavy-metal-resistance proteins, multiple chitinases, and proteins for the detoxification of xenobiotics that may have biotechnological applications

Brazilian Flora 2020: Leveraging the power of a collaborative scientific network

International audienceThe shortage of reliable primary taxonomic data limits the description of biological taxa and the understanding of biodiversity patterns and processes, complicating biogeographical, ecological, and evolutionary studies. This deficit creates a significant taxonomic impediment to biodiversity research and conservation planning. The taxonomic impediment and the biodiversity crisis are widely recognized, highlighting the urgent need for reliable taxonomic data. Over the past decade, numerous countries worldwide have devoted considerable effort to Target 1 of the Global Strategy for Plant Conservation (GSPC), which called for the preparation of a working list of all known plant species by 2010 and an online world Flora by 2020. Brazil is a megadiverse country, home to more of the world's known plant species than any other country. Despite that, Flora Brasiliensis, concluded in 1906, was the last comprehensive treatment of the Brazilian flora. The lack of accurate estimates of the number of species of algae, fungi, and plants occurring in Brazil contributes to the prevailing taxonomic impediment and delays progress towards the GSPC targets. Over the past 12 years, a legion of taxonomists motivated to meet Target 1 of the GSPC, worked together to gather and integrate knowledge on the algal, plant, and fungal diversity of Brazil. Overall, a team of about 980 taxonomists joined efforts in a highly collaborative project that used cybertaxonomy to prepare an updated Flora of Brazil, showing the power of scientific collaboration to reach ambitious goals. This paper presents an overview of the Brazilian Flora 2020 and provides taxonomic and spatial updates on the algae, fungi, and plants found in one of the world's most biodiverse countries. We further identify collection gaps and summarize future goals that extend beyond 2020. Our results show that Brazil is home to 46,975 native species of algae, fungi, and plants, of which 19,669 are endemic to the country. The data compiled to date suggests that the Atlantic Rainforest might be the most diverse Brazilian domain for all plant groups except gymnosperms, which are most diverse in the Amazon. However, scientific knowledge of Brazilian diversity is still unequally distributed, with the Atlantic Rainforest and the Cerrado being the most intensively sampled and studied biomes in the country. In times of “scientific reductionism”, with botanical and mycological sciences suffering pervasive depreciation in recent decades, the first online Flora of Brazil 2020 significantly enhanced the quality and quantity of taxonomic data available for algae, fungi, and plants from Brazil. This project also made all the information freely available online, providing a firm foundation for future research and for the management, conservation, and sustainable use of the Brazilian funga and flora