Theoretical Zero Age Main Sequences revisited

Zero Age Main Sequence (ZAMS) models with updated physical inputs are presented for selected assumptions about the chemical composition, covering the ranges 0.6 < M/Mo < 1.2, 0.0001 < Z < 0.04, 0.23 < Y < 0.34.The HR diagram location of the ZAMS as a function of Y and Z is discussed both in the theoretical and in the observational HR diagrams, showing that the V magnitude presents an increased dependence on Z to be taken into account when discussing observational evidences. Analytical relations quantifying both these dependences are derived. Implications for the galactic helium to heavier elements enrichment are finally discussed.Comment: 4 pages, 4 postscript figures, accepted for publication on Astronomy & Astrophysic

Morphological characteristics of "Monterufoli horse"

Monterufoli horse is a local endangered breed of the Tuscany and derives from the omonym area in province of Pisa. This horse derives from local wild and extinct equines and has Maremmano, Tolfetano and Oriental ancestors. The mean and the standard deviation of biometric characters, and the absolut and percentage frequency of morphological characteristics were calculated. The measures of the adult females were estimated by ANOVA considering three different class of age. The average sizes were: height at withers of 135.4±6.3 and 129.2±5.9, thorax circumference of 166.4±8.3 and 163.4±8.9, frontshank circumference of 17.7±1.5 and 17.5±0.9, for males and females, respectively. All the observed horses presented dark coat. Monterufoli horses showed the physical characteristics of local extinct ancestors (Selvena pony), but also the characteristics of other breeds that contributed to improve the local population. This horse, which was once used in agriculture and for light draught, is now involved for saddle use

Under pressure – The working situation of Swedish healthcare managers during the first wave of COVID-19

Introduction: The aim of this study is to provide insight into the psychosocial work situation of hospital managers during the first wave of the COVID-19 pandemic. Methods: Mixed-effect modelling was used on survey data on job demands, job resources, job motivation, and work-life balance among over 500 managers working in 55 departments of a large Swedish university hospital in 2019 and 2020. Responses from 6011 employees were then used to stratify the analysis for COVID-19 exposure. Inductive content analysis was applied to open-ended questions on the managers’ views on organisational prerequisites during the onset of the pandemic. Results: The proportion of managers reporting difficulties with role clarity, quantitative demands, decision-making authority, and emotional support, time for recovery at work, motivation deficits, or problems with work-life balance clearly increased during the first wave of the pandemic. The proportion of managers reporting negative responses was higher in departments with high COVID-19 exposure. The qualitative analysis shows that overall governance in terms of clear, fair, and well-communicated routines, resource allocation, and division of responsibilities constituted an important framework for managerial during the crisis. First-line managers also require a mandate to re-organize their roles and their teams to successfully adapt to the situation. Organisational and social support was also important resources. Discussion: This is the first study investigating healthcare managers’ work situation during the first wave of the COVID-19 pandemic in a Swedish context. As expected, it indicates an increasingly strained work situation during the crisis, but it also provides findings on organisational prerequisites that allow healthcare managers to cope with stressful situations. In line with previous research on organisational resilience, the study provides suggestions for how higher-level managers can act in order to provide front-line managers with the organisational prerequisites they need to adapt, learn and develop successfully during times of unpredictability, insecurity, and rapid change in order to offer the best possible support to health care workers

Felodipine-Metoprolol Combination Tablet: Maintained Health-Related Quality of Life in the Presence of Substantial Blood Pressure Reduction

Background: Most treated hypertensive patients do not achieve adequate blood pressure (BP) control. Initiating therapy with two drugs has been suggested when BP is >20/10 mm Hg above goal. To ensure patients' compliance, such treatment needs to be well tolerated and must not compromise health-related quality of life (HRQL). The primary objective of this study was to compare the effects on HRQL of initiating treatment with felodipine &plus; metoprolol (F&plus;M) fixed combination tablets, or enalapril (E), or placebo (P). Methods: A total of 947 patients of both sexes with primary hypertension (diastolic BP 95 to 110 mm Hg), aged 20 to 70 years, participated in this randomized, double-blind, parallel group, 12-week, multicenter trial. Treatment was initiated with F&plus;M 5 &plus; 50 mg, or E 10 mg, or P. Doses were doubled after 4 or 8 weeks if diastolic BP was >90 mm Hg. The HRQL was measured at baseline and at the last visit using two validated questionnaires: the Psychological General Well-being Index (PGWB) and the Subjective Symptom Assessment Profile (SSA-P). Office BP was measured at trough, that is, 24 h after the previous dose. Results: The HRQL was high at baseline and generally well maintained during the study. For example, the mean (SD) PGWB total score was 104 (16) at baseline and 105 (16) at 12 weeks in all three treatment groups. The BP reductions after F&plus;M (18/14 mm Hg) and E (12/9 mm Hg) were significantly greater than after P (7/7 mm Hg), and the reduction after F&plus;M was significantly greater than after E. Conclusions: The HRQL is maintained in the presence of substantial BP reduction during antihypertensive treatment with F&plus;M fixed combination tablets. Am J Hypertens 2005;18:1313-1319 © 2005 American Journal of Hypertension, Lt

Felodipine-metoprolol combination tablet: maintained health-related quality of life in the presence of substantial blood pressure reduction.

BACKGROUND: Most treated hypertensive patients do not achieve adequate blood pressure (BP) control. Initiating therapy with two drugs has been suggested when BP is &amp;gt;20/10 mm Hg above goal. To ensure patients' compliance, such treatment needs to be well tolerated and must not compromise health-related quality of life (HRQL). The primary objective of this study was to compare the effects on HRQL of initiating treatment with felodipine + metoprolol (F+M) fixed combination tablets, or enalapril (E), or placebo (P). METHODS: A total of 947 patients of both sexes with primary hypertension (diastolic BP 95 to 110 mm Hg), aged 20 to 70 years, participated in this randomized, double-blind, parallel group, 12-week, multicenter trial. Treatment was initiated with F+M 5 + 50 mg, or E 10 mg, or P. Doses were doubled after 4 or 8 weeks if diastolic BP was &amp;gt;90 mm Hg. The HRQL was measured at baseline and at the last visit using two validated questionnaires: the Psychological General Well-being Index (PGWB) and the Subjective Symptom Assessment Profile (SSA-P). Office BP was measured at trough, that is, 24 h after the previous dose. RESULTS: The HRQL was high at baseline and generally well maintained during the study. For example, the mean (SD) PGWB total score was 104 (16) at baseline and 105 (16) at 12 weeks in all three treatment groups. The BP reductions after F+M (18/14 mm Hg) and E (12/9 mm Hg) were significantly greater than after P (7/7 mm Hg), and the reduction after F+M was significantly greater than after E. CONCLUSIONS: The HRQL is maintained in the presence of substantial BP reduction during antihypertensive treatment with F+M fixed combination tablets

Helioseismic constraints to the central solar temperature and neutrino fluxes

The central solar temperature T and its uncertainties are calculated in helioseismologically-constrained solar models. From the best fit to the convective radius, density at the convective radius and seismically determined helium abundance the central temperature is found to be T=1.58x10^7 K, in excellent agreement with Standard Solar Models. Conservatively, we estimate that the accuracy of this determination is Delta T/T=1.4 %, better than that in SSM. Neutrino fluxes are calculated. The lower limit to the boron neutrino flux, obtained with maximum reduction factors from all sources of uncertainties, is 2 sigma higher than the flux measured recently by SuperKamiokande.Comment: Latex, 10 pages, uses revtex styles (included), 3 postscript figure

Madri e miti. Hot Milk di Deborah Levy. Traduzione e commento

Una madre, in cerca di un miracolo medico, e una figlia, bloccata in uno stato di paralisi mentale, si recano ad Almeria, nel sud della Spagna, per una consulenza medica del tanto discusso dottor Gomez. Un'analisi sul rapporto madre-figlia ormai alla deriva e una crisi di identità di Sofia, mostrati attraverso il mito di Medusa