A study on bacterial vaginosis in pregnancy and its effect on pregnancy outcome

Background: Bacterial vaginosis is an extremely prevalent vaginal condition and one of the causes of vaginitis among both pregnant and non pregnant women and associated with severe sequelae. Fifty percent of the women are asymptomatic. Current studies have found that the prevalence of BV ranges from 15% to 30% among non-pregnant women and 10% to 41% among pregnant women.Methods: This is a prospective study conducted among 150 pregnant women who attended the antenatal outpatient and inpatient clinic in the Department of Obstetrics and Gynaecology at Narayana Medical College and Hospital, Nellore over a period of two years from Oct 2016 to Oct 2018. Obstetric cases fulfilling the inclusion and exclusion criteria were enrolled in the study by convenient sampling technique. They were followed till the outcome of pregnancy. The data was subjected to usual statistical analysis by employing the chi-square tests.Results: Prevalence of the bacterial vaginosis was 20% in the present study. BV was significantly (p0.05) between BV positive and negative women.Conclusions: Considering the vast spectrum of maternal and fetal morbidity associated with this infection, and the availability of rapid inexpensive diagnostic tests it may be prudent to screen BV in pregnancy, so that it may be treated early and hence prevent the adverse pregnancy outcomes

സാമ്പിൾ ശേഖരണം ശാസ്ത്രീയ മണ്ണുപരിശോധനയ്ക്ക്

സാമ്പിൾ ശേഖരണം ശാസ്ത്രീയ മണ്ണുപരിശോധനയ്ക്ക് Sample collection for scientific soil analysi

Power Generalized KM-Transformation for Non-Monotone Failure Rate Distribution

Lifetime models with a non-monotone hazard rate $\hspace{0.12cm}$ function have a wide range of applications in engineering and lifetime data analysis. There are different bathtub shaped failure rate models that are available in reliability literature. Kavya and Manoharan (2021) introduced a new transformation called KM-transformation which was found to be more useful in reliability and lifetime data analysis. Power generalization technique would be the best approach to deal with a system whose components are connected in series, in which the distribution of the component is KM-transformation of any lifetime model. In this article, we introduce a new lifetime model, Power Generalized KM-Transformation (PGKM) for Non-Monotone Failure Rate Distribution, which shows monotone and non-monotone behavior for the hazard rate function for different choices of values of parameters. We derive the moments, moment generating function, characteristic function, quantiles, entropy etc of the proposed distribution. Distributions of minimum and maximum are obtained. Estimation of parameters of the distribution is performed via maximum likelihood method. A simulation study is performed to validate the maximum likelihood estimator (MLE). Analysis of three sets of real data are given

SCREENING OF WOUND HEALING ACTIVITY OF MADAYANTIKA (LAWSONIA INERMIS LINN.) IN ALBINO WISTAR RATS

Madayantika (Lawsonia inermis Linn.) is a miracle medicinal plant used in the treatment of various skin diseases especially in wound healing activity in the Indian system of medicine. Aim and Objective: The objective of the study presented in this article was to evaluate the wound healing potential of aqueous extract. The models usually used for evaluation of wound healing activity are Excision wound model, Incision Wound Model and Dead Space model. Among those excisions wound model is selected for the study. Healthy wistar strain Albino rats of either sex weighing 150-200gm were used for the study. Animals are acclimatized in a laboratory and then it were anaesthetized and then dorsal surface of rats were shaved to about an area of 500mm2 and then it was cut carefully with sterilized forceps and left undressed for open environment, then extracts of test drugs, Scaffolds containing aqueous extract and standard drug were applied and then observed and noted. Results: The extract of Madayantika (Lawsonia inermis Linn.) treated wounds were found to epithelize faster and rate of wound contraction was significantly (p<0.0001) increased as compared to control group (p< 0.01). The extract treated animals showed from 502 ±0.364 to 25.1±0.252 reduction in wound area when compared with control groups from 502± 0.538 to 40.71± 0.166. Conclusion: Madayantika (Lawsonia inermis Linn.) possess significant wound healing effect which may beneficial in treating wounds. This drug showed extremely significant results in wound healing activity

Intervention of Talent Management Impact on the HR Practices among the Employees Working in the Software Industries.

Recruitment of applicants with highly valued talents, provision of continual learning and development opportunities, reward of important team members, and encouragement of advancement within the organization are all common and best practices in talent management (more on these practices below). Numerous examples exist of Indian businesses successfully keeping key employees on staff. Such organizations use alternative methods of talent management. In majority of these situations, such Indian organizations have a heritage of at least hundred years. Some startups and family-run enterprises are also successful in the talent acquisition and retention arena. This case study looks at how one Indian company's talent management practices led to the retention of a key employee. The case, which is based on research on the methods used by several Indian companies to manage their employees' talents, stresses the value of teamwork. The concept of collegiality in the context of talent management has received little attention. This case note is an attempt to spark conversations on how organizations might improve their talent management practices via the use of collaborative strategies. The term "talent management" refers to a company's approach to finding and keeping the best possible staff. Motivated workers who are also strategically aligned have a greater chance of advancing in their current positions and eventually taking on leadership responsibilities. YES, Bank staff in the Indian cities of Hyderabad, Bangalore, and Chennai participated in the researc

A Novel Method for Rapid and Selective Extraction of Male DNA from Rape Kits using Alkaline Lysis and Pressure Cycling Technology (PCT)

There is an increasing demand for DNA analysis because of the sensitivity of the method and the ability to uniquely identify and distinguish individuals with a high degree of certainty. But this demand has led to huge backlogs in evidence lockers since the current DNA extraction protocols require long processing time. The DNA analysis procedure becomes more complicated when analyzing sexual assault casework samples where the evidence contains more than one contributor. Additional processing to separate different cell types in order to simplify the final data interpretation further contributes to the existing cumbersome protocols. The goal of the present project is to develop a rapid and efficient extraction method that permits selective digestion of mixtures. Selective recovery of male DNA was achieved with as little as 15 minutes lysis time upon exposure to high pressure under alkaline conditions. Pressure cycling technology (PCT) is carried out in a barocycler that has a small footprint and is semi-automated. Typically less than 10% male DNA is recovered using the standard extraction protocol for rape kits, almost seven times more male DNA was recovered from swabs using this novel method. Various parameters including instrument setting and buffer composition were optimized to achieve selective recovery of sperm DNA. Some developmental validation studies were also done to determine the efficiency of this method in processing samples exposed to various conditions that can affect the quality of the extraction and the final DNA profile. Easy to use interface, minimal manual interference and the ability to achieve high yields with simple reagents in a relatively short time make this an ideal method for potential application in analyzing sexual assault samples

North Pacific Decadal Variability in the GEOS-5 Atmosphere-Ocean Model

This study examines the mechanisms of the Pacific decadal oscillation (PDO) in the GEOS-5 general circulation model. The model simulates a realistic PDO pattern that is resolved as the first empirical orthogonal function (EOF) of winter sea surface temperature (SST). The simulated PDO is primarily forced by Aleutian low through Ekman transport and surface fluxes, and shows a red spectrum without any preferred periodicity. This differs from the observations, which indicate a greater role of El Nino-Southern Oscillation (ENSO) forcing, and likely reflects the too short time scale of the simulated ENSO. The geostrophic transport in response to the Aleutian low is limited to the Kuroshio-Oyashio Extension, and is unlikely the main controlling factor in this model, although it reinforces the Ekman-induced SST anomalies. The delay between the Aleutian low and the PDO is relatively short (1 year) suggesting that the fast Ekman response (rather than Rossby wave propagation) sets the SST pattern immediately following an Aleutian low fluctuation. The atmospheric feedback (response to the SST) is only about 25 of the forcing and never evolves into an Aleutian low completely, instead projecting onto the North Pacific Oscillation (NPO), a meridional dipole in sea level pressure (SLP). The lack of preferred periodicity and weak atmospheric response bothindicate a coupled oscillation is an unlikely mechanism for the PDO in this model. In agreement with recent studies, the NPO is correlated with the North Pacific Gyre Oscillation (NPGO), which is another leading EOF of the North Pacific SST. A possible connection between the PDO and the NPGO is discussed

ANALYSIS AND MODELING OF THE SHUNT ACTIVE POWER FILTER WITH A SYSTEM OF CLOSED LOOP CONTROL OF THE ELECTRICAL POWER PLANES

The main objective of this project is the analysis and modeling of shunt APF with document control loop, it is proposed to compensate forward feed the load current to improve the dynamic behavior of the APF route. three stage inverter cascade H- bridge airway (APF AAPF) is determined. And increased levels of control to improve the performance of the APF. Increase the level of control can increase the reliability of the power and quality of aircraft energy system. And it provided a framework and functioning of the proposal of the International School of AAPF in detail. The application of the control strategy and cascading fountain I topology DC converter in AAPF proposed. power quality characteristics of the traditional system does not meet. EPS performance characteristics with traditional systems are not the best. The proposed method is to solve EPS quality characteristics of jets force the issue. To overcome the stability problems. total harmonic distortion (THD) of the power supply in a wide range of system frequency is reduced. To check the performance of the AAPF compensation proposal and implementation of this system with the control system in mat lab / Simulink

Evaluation of screening efficacy of IL6, IL8, CRP and salivary progesterone in predicting preterm pregnancy

Background: According to WHO preterm birth defined as births occurring before completion of 37 weeks, in a pregnancy beyond 20 weeks of gestation. As reported by W.H. O preterm birth has incidence of about 9.6% of all the live births, preterm births have high neonatal morbidity and mortality. In this review we look at association between CRP, IL6, IL8 and salivary progesterone in predicting the preterm delivery. Methods: A hospital based prospective study to be conducted in a group of 100 women of 20- 24 weeks of gestation, they were analysed for IL6, IL8, CRP and salivary progesterone and followed them till delivery. Results: On assessment of the biomarkers to predict the preterm and term pregnancy, we assessed for the blood level of CRP, IL6, IL8 and salivary progesterone among the pregnant women at 20-24 weeks of gestation and followed till the pregnancy outcomes. Among which 46% were with preterm pregnancy and 54% with term pregnancy during delivery. Among them, 20% had the previous preterm pregnancy and 80% were not. We found 70% with normal vaginal delivery, 24% with emergency LSCS and 6% with elective LSCS. Conclusions: The present study documented the significant higher efficacy of IL6, IL8, CRP and salivary progesterone in predicting the preterm pregnancy. Progesterone levels in the saliva was markedly lower among the pregnancy with preterm delivery compared to term delivery outcome. The fetal outcome among the preterm delivery was significantly with morbidity and mortality compared to term delivery. The ROC curve showed the estimation of IL6, IL8, CRP and salivary progesterone at 20-24 weeks of gestation can predict the outcome of preterm pregnancy