Üst Keser Dişlerde Meydana Gelen Travma Sonrası Multidisipliner Tedavi Yaklaşımı: Bir Olgu Sunumu

Amaç: Travma sonrası dişlerde hasar meydana gelmesi sıklıkla karşılaşılan problemlerdendir. Daimi dentisyon sırasında medya gelen travmalarda ise kesici dişlerin avülsüyonuna rastlanabilir. Bu durumlarda splintlenme önerilmekte ancak çapraşıklığı olan olgularda travma sonrası splint yapımında güçlükler yaşanabilmektedir. Bu vaka raporunda amaç travma sonrasında fiber ile güçlendirilmiş lingual retainerın splint olarak etkinliğini ve iyileşme sonrası yapılan ortodontik ve protetik tedavileri göstermektir. Olgu sunumu: 22 yaşındaki bayan hasta travma sonrası üst kesici dişlerinde hasar şikayetiyle başvurmuştur. Alınan anamnezde avülse olan kesici dişin ilk başvurduğu hekim tarafından soket içerisine yerleştirilmeye çalışılıp fakültemize gönderildiği anlaşılmıştır. Yapılan reimplantasyon işleminden sonra fiber ile güçlendirilmiş lingual retainer ile dişler splintlenmiştir. Takip döneminden sonra sol üst orta kesici dişin çekimi gerekmiş ve sol üst yan kesici diş ortodontik tedavi ile sol orta kesicinin yerine getirilmiş ve uygun protetik tedaviler yapılmıştır. Sonuç: Çapraşıklığı bulunan travma hastalarında ağız içerisinde kompozit tel kombinasyonu splint yapımı zor olduğundan fiber ile güçlendirilmiş lingual retainer bir alternatif olabilir

An analysis of the graduate thesis studies conducted on the primary school mathematics education between the years 2016 and 2020 in Turkey

Bu araştırmanın amacı ilkokul matematik eğitimi alanında yapılmış olan lisansüstü tezlerin incelenmesidir. Çalışmada, Türkiye’de ilkokul matematik eğitimi alanında 2016-2020 yılları arasında hazırlanan lisansüstü tezler türleri, yapıldıkları yıllar, kullanılan yöntemler, örneklem-çalışma grubu, ele alınan konular gibi çeşitli açılardan incelenmiştir. Bu kapsamda üç araştırma sorusuna cevap aranmıştır. Nitel araştırma yöntemlerinden doküman inceleme yönteminden yararlanılan araştırmada, Türkiye’de ilkokul matematik eğitimi alanında hazırlanan, Yüksek Öğretim Kurumu (YÖK) tarafından 2016-2020 yılları arasında onaylanan ve arşivlenen toplam 125 lisansüstü tez incelenmiştir. Araştırma verileri içerik analiz yöntemi kullanılarak çözümlenmiştir. Araştırmanın sonucunda; en fazla yüksek lisans tezinin hazırlandığı, tezlerin hazırlandıkları yıllara göre sayılarında dalgalanma olduğu, çalışma grubu olarak dördüncü sınıf öğrencilerinin çoğunlukta olduğu, konu alanı olarak “sayılar ve işlemler” öğrenme alanında gerçekleştirildikleri, nicel araştırmaların daha fazla tercih edildikleri bulgusuna ulaşılmıştır.The purpose of the current study is to analyze the graduate thesis studies conducted in the field of primary school mathematics education. To this end, the thesis studies conducted in the field of primary school mathematics education between the years 2016 and 2020 in Turkey were analyzed in terms of their type, the year in which they were written, the methods used, the sample-study group, and the subjects being researched. In the study employing the document analysis method, one of the qualitative research methods, a total of 125 graduate theses written in the field of primary school mathematics education in Turkey and approved and archived by the Higher Education Council (HEC) between the years 2016 and 2020 were analyzed. The data of the study were analyzed by using the content analysis method. As a result of the study, it was found that from among the theses, the number of the master’s theses is the highest, that the number of theses written across the years fluctuated, that fourthgrade students were preferred the most for study groups, that the subjects examined in the theses were mostly focused on “numbers and operations” and that qualitative research methods were preferred more

Thermodynamic analysis of a diesel engine fueled with diesel and sesame oil biodiesel

European Biotechnology Conference -- MAY 05-07, 2016 -- LATVIAWOS: 000380240300142

Evaluation of prognostic factors and treatment in advanced small bowel adenocarcinoma: report of a multi-institutional experience of anatolian Society of medical oncology (ASMO)

WOS: 000388782200027PubMed ID: 27837629Purpose: Small bowel adenocarcinoma (SBA) is a rare tumor of the gastrointestinal system with poor prognosis. Since these are rarely encountered tumors, there are limited numbers of studies investigating systemic treatment in advanced SBA. The purpose of this study was to evaluate the prognostic factors and systemic treatments in patients with advance SBA. Methods: Seventy-one patients from 18 Centers with advanced SBA were included in the study. Fifty-six patients received one of the four different chemotherapy regimens as first-line therapy and 15 patients were treated with best supportive care (BSC). Results: Of the 71 patients, 42 (59%) were male and 29 (41%) female with a median age of 56 years. Median follow-up duration was 14.3 months. The median progression free survival (PFS) and overall survival (OS) were 7 and 13 months, respectively (N=71). In patients treated with FOLFOX (N=18), FOLFIRI (N=11), cisplatin-5-fluoroura-cil/5-FU (N=17) and gemcitabine alone (N=10), median PFS was 7, 8, 8 and 5 months, respectively, while median OS was 15, 16, 15 and 11 months, respectively. No significant differences between chemotherapy groups were noticed in terms of PFS and OS. Univariate analysis revealed that chemotherapy administration, de novo metastatic disease, ECOG PS 0 and 1, and overall response to therapy were significantly related to improved outcome. Only overall response to treatment was found to be significantly prognostic in multivariate analysis (p = 0.001). Conclusions: In this study, overall response to chemotherapy emerged as the single significant prognostic factor for advanced SBAs. Platin and irinotecan based regimens achieved similar survival outcomes in advanced SBA patients

Evaluation of prognostic factors and treatment in advanced small bowel adenocarcinoma: report of a multi-institutional experience of Anatolian Society of Medical Oncology (ASMO)

Purpose: Small bowel adenocarcinoma (SBA) is a rare tumor of the gastrointestinal system with poor prognosis. Since these are rarely encountered tumors, there are limited numbers of studies investigating systemic treatment in advanced SBA. The purpose of this study was to evaluate the prognostic factors and systemic treatments in patients with advance SBA

Efficacy and safety of folfiri plus aflibercept in second-line treatment of metastatic colorectal cancer: Real-life data from Turkish oncology group

Aims: The addition of aflibercept to the fluorouracil and irinotecan (FOLFIRI) regimen significantly improved clinical outcomes in patients with metastatic colorectal cancer (CRC) previously treated with oxaliplatin. We aimed to investigate the efficacy and safety of second-line FOLFIRI and aflibercept combination in patients with metastatic CRC in real-life experience. Materials and Methods: Four hundred and thirty-three patients who treated with FOLFIRI and aflibercept in the second-line were included in the study. The clinical and pathological features of the patients were recorded retrospectively. Survival (overall and progression-free survival [PFS]), response rates, and safety data were analyzed. Results: The median age was 61. Majority of patients (87.5%) received first-line bevacizumab and 10.1% of patients received anti-epidermal growth factor receptor agents. About 80% of patients had KRAS, 18.6% of patients had NRAS, and 6.4% of patients had BRAF mutations. The median OS was 11.6 months (95% confidence interval [CI], 10.6-12.6) and the median PFS was 6 months (95% CI, 5.5-6.5). About 4.6% of patients had complete response and 30.6% of patients had partial response as best tumor response. Grade 1-2 toxicities were seen in 33.4% of patients, while grade 3-4 toxicities were recorded in 27% of patients. Eight patients (2%) died due to treatment toxicity. Conclusions: Overall and PFS were similar in routine clinical practice compared to phase III pivotal VELOUR trial. However, response rates were found to be higher. It was observed that there were fewer adverse events compared to the VELOUR trial