The Moderating Role of Emotional Intelligence on the Relationship Between Perceptions of Organizational Politics and Work Outcomes

This study investigates the moderating role of emotional intelligence (EI) on the relationship between perceptions of organizational politics(POP) and work outcomes. In addition, it also examined the effects of POP and EI on work outcomes. Participants (n=332) from three public universities in Amhara region, Ethiopia has been selected using simple random sampling techniques. Results from structural equation modeling (SEM) shows that perceptions of organization politics (POP) are negatively linked to job satisfaction and affective commitment. Further, EI was positively related to job satisfaction and affective commitment. However, to the proposed moderating effects of EI, support was provided for job satisfaction only

A computationally efficient frequency-domain filtered-X LMS algorithm for virtual microphone

The computational complexity of the virtual FXLMS algorithm is higher than that of the conventional FXLMS algorithm. The additional complexity comes from computation of three secondary path transfer functions (as opposed to one) and a transfer function between the physical and the virtual microphones. The order of these transfer functions may be very high in practical situations where the acoustic damping is low. The high computational complexity of the virtual FXLMS algorithm imposes issues like high power consumption, making it difficult to implement the algorithm in battery operated ANC devices such as active headsets. In addition, the operating sampling frequency of the algorithm is limited and this in turn restricts its operation to relatively low frequency applications. In this paper, a new virtual FXLMS algorithm is derived by implementing all of the secondary path transfer functions in the frequency domain. The algorithm is simulated using measured transfer functions in a duct with low acoustic damping. Implementation schemes are proposed for the new frequency-domain virtual FXLMS algorithm, citing its advantages for use as an efficient real-time active noise control algorithm. © 2013 Elsevier Ltd.Debi Prasad Das, Danielle J. Moreau, Ben S.Cazzolat

Co-existing malakoplakia and xanthogranulomatous pyelonephritis of kidney: Two different spectrum of same disease process

Xanthogranulomatous pyelonephritis (XGP) and malakoplakia (MKP) are chronic inflammatory condition of kidney characterized by infiltration of inflammatory cells. We are presenting a rare case of concomitant XGP and MKP in the same kidney. This signifies that the two are different spectrums of the same disease process

Binding of antigalactosyl antibody to galactosylated liposomes

The binding characteristics of rabbit anti-galactosyl antibodies elicited through galactosylated liposomes were studied. The association constants (13 × 10<SUP>5</SUP> M<SUP>−1</SUP> and 21 × 10<SUP>5</SUP> M<SUP>−1</SUP> of Fabμ and Fab fragments with the galactosylated liposomes were determined by measuring the binding of radioiodinated antibodies. The effect of free ligand (methyl-β-D-galactopyranoside) and the ligand coupled to the liposomal surface (galactosylated liposomes) on the structure of antibodies was investigated using circular dichroism (CD) measurements. Changes were observed in both the secondary and tertiary structure of antibodies upon binding to galactosylated liposomes. In contrast, the free ligand induced alterations only in the near-UV region of the CD spectra, indicating a change in tertiary structure only

Peptidyl transferase activity of tRNA: A quantum chemical study

48-52The mechanism of protein synthesis is still unknown due to inability to detect the so-called enzyme "peptidyl transferase" even after elucidation of high-resolution crystal structure of ribosome. We have recently shown by model building and semi-empirical energy calculations that the tRNA molecule at P-site of ribosome may act as peptidyl transferase (Das et al. (1999) J. Theo. Biol. 200, 193-205). We proposed that the tetrahedral intermediate formed from nucleophylic attack of CO of P-site amino-acylated tRNA by NH2 of A-site amino-acy lated tRNA is converted to a six member ring intermediate by conformational change. This ring intermediate produces a free tRNA and a tRNA covalently linked to a peptide. However, energy of the six-member ring intermediate was calculated to be quite high. We show here that the energy values of all the reactants, intermediates and products are within the expected range when they are calculated using high level ab initio quantum chemical methods

Dual role of liposomes as adjuvant and carrier for the production of sugar-specific antibodies

Aminophenyl derivatives of monosaccharides were coupled to the surface of phosphatidylethanolamine containing liposomes. The glycosylated liposomes elicited in rabbits a hapten-specific immune response. The magnitude of antibody formation was nearly equivalent in the presence and the absence of Freund's adjuvant. The antibody response mediated through liposomes was better than that obtained through the protein carrier

Understanding perception of active noise control system through multichannel EEG analysis

In this Letter, a method is proposed to investigate the effect of noise with and without active noise control (ANC) on multichannel electroencephalogram (EEG) signal. The multichannel EEG signal is recorded during different listening conditions such as silent, music, noise, ANC with background noise and ANC with both background noise and music. The multiscale analysis of EEG signal of each channel is performed using the discrete wavelet transform. The multivariate multiscale matrices are formulated based on the sub-band signals of each EEG channel. The singular value decomposition is applied to the multivariate matrices of multichannel EEG at significant scales. The singular value features at significant scales and the extreme learning machine classifier with three different activation functions are used for classification of multichannel EEG signal. The experimental results demonstrate that, for ANC with noise and ANC with noise and music classes, the proposed method has sensitivity values of 75.831% ([inline-formula]) and 99.31% ([inline-formula]), respectively. The method has an accuracy value of 83.22% for the classification of EEG signal with music and ANC with music as stimuli. The important finding of this study is that by the introduction of ANC, music can be better perceived by the human brain

Targeted delivery of hepatitis C virus-specific short hairpin RNA in mouse liver using Sendai virosomes

Internal ribosome entry site (IRES)-mediated translation of input viral RNA is the initial required step for the replication of the positive-stranded genome of hepatitis C virus (HCV). We have shown previously the importance of the GCAC sequence near the initiator AUG within the stem and loop IV (SLIV) region in mediating ribosome assembly on HCV RNA. Here, we demonstrate selective inhibition of HCV-IRES-mediated translation using short hairpin (sh)RNA targeting the same site within the HCV IRES. sh-SLIV showed significant inhibition of viral RNA replication in a human hepatocellular carcinoma (Huh7) cell line harbouring a HCV monocistronic replicon. More importantly, co-transfection of infectious HCV-H77s RNA and sh-SLIV in Huh7.5 cells successfully demonstrated a significant decrease in viral RNA in HCV cell culture. Additionally, we report, for the first time, the targeted delivery of sh-SLIV RNA into mice liver using Sendai virosomes and demonstrate selective inhibition of HCV-IRES-mediated translation. Results provide the proof of concept that Sendai virosomes could be used for the efficient delivery of shRNAs into liver tissue to block HCV replication