A comprehensive analysis of the epidemiology and clinical characteristics of anti-LRP4 in myasthenia gravis

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Inherited congenital goiter in mice.

Congenital goiter (cog), a new autosomal recessive mutation in mice, has been mapped to the central region of chromosome 15. Young adult mutant mice are characterized by a reduced rate of growth, mild anemia, hypothyroidism, as indicated by significantly lower total serum T4 and T3, and elevated serum TSH. Thyroids from mutant mice are hypertrophied, deficient in colloid, show a reduced accumulation of iodine that is partially susceptible to perchlorate ion discharge, have modestly elevated serum immunoreactive thyroglobulin (Tg) levels, but are markedly deficient in glandular immunoreactive Tg content. Thyroid hormone therapy corrects the growth deficiency and prevents the thyroid hypertrophy resulting from excessive stimulation by TSH. These findings suggest that the cog mutant gene results in primary hypothyroidism in response to either defective synthesis or processing of Tg

A Tonality-oriented Symbolic Representation of Musical Audio Generated by Classification Trees

info:eu-repo/semantics/publishe

Thermal Hydraulic Study of a Single Row Heat Exchanger With Helically Finned Tubes

In this study, the heat transfer and friction correlation of a single row heat exchanger with helically finned tubes are experimentally determined. The transversal tube pitch was parametrically varied. A detailed description of the test rig and the data reduction procedure is given. A thorough uncertainty analysis was performed to validate the results. The proposed heat transfer correlation can describe 95% of the data within +/- 11% and shows a 4.49% mean deviation. The friction correlation predicts 95% of the data within +/- 19% with a mean deviation of 6.84%. The new correlations show the same trend as most correlations from open literature, but none of the literature correlations are able to accurately predict the results of this study