8,120 research outputs found
Biocatalysis as Useful Tool in Asymmetric Synthesis: An Assessment of Recently Granted Patents (2014–2019)
The broad interdisciplinary nature of biocatalysis fosters innovation, as different technical fields are interconnected and synergized. A way to depict that innovation is by conducting a survey on patent activities. This paper analyses the intellectual property activities of the last five years (2014–2019) with a specific focus on biocatalysis applied to asymmetric synthesis. Furthermore, to reflect the inventive and innovative steps, only patents that were granted during that period are considered. Patent searches using several keywords (e.g., enzyme names) have been conducted by using several patent engine servers (e.g., Espacenet, SciFinder, Google Patents), with focus on granted patents during the period 2014–2019. Around 200 granted patents have been identified, covering all enzyme types. The inventive pattern focuses on the protection of novel protein sequences, as well as on new substrates. In some other cases, combined processes, multi-step enzymatic reactions, as well as process conditions are the innovative basis. Both industries and academic groups are active in patenting. As a conclusion of this survey, we can assert that biocatalysis is increasingly recognized as a useful tool for asymmetric synthesis and being considered as an innovative option to build IP and protect synthetic routes
The establishment of Diachasmimorpha longicaudata (Hymenoptera: Braconidae) in Misiones, Northeastern Argentina
The establishment of Diachasmimorpha longicaudata (Ashmead) on Anastrepha fraterculus (Wiedemann) in the northeastern province of Misiones, Argentina, is described.Fil: Schliserman, Pablo. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina. Universidad Nacional de Tucumán. Facultad de Ciencias Naturales e Instituto Miguel Lillo; Argentina. Fundación Miguel Lillo. Centro de Investigaciones para la Regulación de Poblaciones de Organismos Nocivos; ArgentinaFil: Ovruski Alderete, Sergio Marcelo. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina. Universidad Nacional de Tucumán. Facultad de Ciencias Naturales e Instituto Miguel Lillo; Argentina. Fundación Miguel Lillo. Centro de Investigaciones para la Regulación de Poblaciones de Organismos Nocivos; ArgentinaFil: De Coll, Olga R.. Instituto Nacional de TecnologÃa Agropecuaria; Argentin
Low-temperature anomalies of a vapor deposited glass
We investigate the low temperature properties of two-dimensional
Lennard-Jones glass films, prepared in silico both by liquid cooling and by
physical vapor deposition. We identify deep in the solid phase a crossover
temperature , at which slow dynamics and enhanced heterogeneity emerge.
Around , localized defects become visible, leading to vibrational
anomalies as compared to standard solids. We find that on average,
decreases in samples with lower inherent structure energy, suggesting that such
anomalies will be suppressed in ultra-stable glass films, prepared both by very
slow liquid cooling and vapor deposition.Comment: 10 pages including appendices, 8 figures. Version accepted for
Physical Review Material
Ideal isotropic auxetic networks from random networks
Auxetic materials are characterized by a negative Poisson's ratio,
. As the Poisson's ratio becomes negative and approaches the
lower isotropic mechanical limit of , materials show
enhanced resistance to impact and shear, making them suitable for applications
ranging from robotics to impact mitigation. Past experimental efforts aimed at
reaching the limit have resulted in highly anisotropic
materials, which show a negative Poisson's ratio only when subjected to
deformations along specific directions. Isotropic designs have only attained
moderately auxetic behavior, or have led to structures that cannot be
manufactured in 3D. Here, we present a design strategy to create isotropic
structures from disordered networks that leads to Poisson's ratios as low as
. The materials conceived through this approach are
successfully fabricated in the laboratory and behave as predicted. The
Poisson's ratio is found to depend on network structure and bond
strengths; this sheds light on the structural motifs that lead to auxetic
behavior. The ideas introduced here can be generalized to 3D, a wide range of
materials, and a spectrum of length scales, thereby providing a general
platform that could impact technology.Comment: 16 pages, 6 figure
Dissolution experiments of commercial PWR (52 MWd/kgU) and BWR (53 MWd/kgU) spent nuclear fuel cladded segments in bicarbonate water under oxidizing conditions. Experimental determination of matrix and instant release fraction
The denominated instant release fraction (IRF) is considered in performance assessment (PA) exercises to govern the dose that could arise from the repository. A conservative definition of IRF comprises the total inventory of radionuclides located in the gap, fractures, and the grain boundaries and, if present, in the high burn-up structure (HBS). The values calculated from this theoretical approach correspond to an upper limit that likely does not correspond to what it will be expected to be instantaneously released in the real system. Trying to ascertain this IRF from an experimental point of view, static leaching experiments have been carried out with two commercial UO2 spent nuclear fuels (SNF): one from a pressurized water reactor (PWR), labelled PWR, with an average burn-up (BU) of 52 MWd/kgU and fission gas release (FGR) of 23.1%, and one from a boiling water reactor (BWR), labelled BWR, with an average BU of and 53 MWd/kgU and FGR of 3.9%.; One sample of each SNF, consisting of fuel and cladding, has been leached in bicarbonate water during one year under oxidizing conditions at room temperature (25 +/- 5) degrees C. The behaviour of the concentration measured in solution can be divided in two according to the release rate. All radionuclides presented an initial release rate that after some days levels down to a slower second one, which remains constant until the end of the experiment. Cumulative fraction of inventory in aqueous phase (FIAPc) values has been calculated. Results show faster release in the case of the PWR SNF. In both cases Np, Pu, Am, Cm, Y, Tc, La and Nd dissolve congruently with U, while dissolution of Zr, Ru and Rh is slower. Rb, Sr, Cs and Mo, dissolve faster than U. The IRF of Cs at 10 and 200 days has been calculated, being (3.10 +/- 0.62) and (3.66 +/- 0.73) for PWR fuel, and (035 +/- 0.07) and (0.51 +/- 0.10) for BWR fuel. (C) 2015 Elsevier B.V. All rights reserved.Peer ReviewedPostprint (author's final draft
Solution of a model of SAW's with multiple monomers per site on the Husimi lattice
We solve a model of self-avoiding walks which allows for a site to be visited
up to two times by the walk on the Husimi lattice. This model is inspired in
the Domb-Joyce model and was proposed to describe the collapse transition of
polymers with one-site interactions only. We consider the version in which
immediate self-reversals of the walk are forbidden (RF model). The phase
diagram we obtain for the grand-canonical version of the model is similar to
the one found in the solution of the Bethe lattice, with two distinct
polymerized phases, a tricritical point and a critical endpoint.Comment: 16 pages, including 6 figure
The establishment of Aceratoneuromyia indica (Hymenoptera: Eulophidae) in three biogeographical regions of Argentina
Specimens of the eulophid Aceratoneuromyia indica (Silvestri) were recovered from fruit fly pupae collected in three Argentinian biogeographical regions. A total of 11 A. indica specimens was obtained from pupae of the tephritid Anastrepha fraterculus (Wiedemann) in Las Yungas and Paranaense subtropical rain forest regions, and 10 A. indica specimens were recovered from pupae of the tephritid Ceratitis capitata (Wiedemann) in Chacoan subtropical dry forest region.Thus, A. indica was recovered approximately 38 years after its first release in Argentina.Fil: Ovruski Alderete, Sergio Marcelo. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; ArgentinaFil: Schliserman, Pablo. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; ArgentinaFil: De Coll, Olga R.. Instituto Nacional de TecnologÃa Agropecuaria; ArgentinaFil: Peñaloza, Claudia. Instituto Nacional de TecnologÃa Agropecuaria; ArgentinaFil: Oroño, Luis Eduardo. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; ArgentinaFil: Colina, Carolina del Valle. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Centro CientÃfico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentin
Orthogonal Bases of Invariants in Tensor Models
Representation theory provides a suitable framework to count and classify
invariants in tensor models. We show that there are two natural ways of
counting invariants, one for arbitrary rank of the gauge group and a second,
which is only valid for large N. We construct bases of invariant operators
based on the counting, and compute correlators of their elements. The basis
associated with finite N diagonalizes the two-point function of the theory and
it is analogous to the restricted Schur basis used in matrix models. We comment
on future lines of investigation.Comment: Two overlapping but independent results are merged to a joint work.
16 pages, 1 tabl
A set of primers for length and nucleotide-substitution polymorphism in chloroplastic DNA of Olea europaea L. (Oleaceae)
Chloroplastic DNA (cpDNA) variation at five microsatellite motifs, two insertion-deletion sites, and eight nucleotide substitution sites was investigated in the Olea europaea complex. Primers were designed for flanking regions of these sites to amplify short cpDNA regions. They provided polymorphism when polymerase chain reaction (PCR) products from a representative sample of 128 O. europaea individuals were either resolved by size into polyacrylamide gels (length polymorphism) or digested with restriction enzymes (nucleotide-substitution polymorphism). These polymorphisms serve to distinguish most of the cytoplasmic haplotypes previously recognized. Potential application of these markers in O. europaea includes phylogeography, conservation and germplasm identification, even when using poorly preserved material from herbarium specimens or forensic and archaeological materials.This work was supported by the project BIOD-IBERIA (A82).Peer Reviewe
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