Theoretical model for cascading effects analyses

Abstract In case of exceptional events of natural or anthropogenic type, the elements at risk (people, buildings, infrastructures, economy, etc.) are often hit by sequences of 'cascading events', function of time and space, caused by the triggering event (earthquake, landslide, volcanic eruption, fire, electric failure, etc.). Generally, sequences of events can involve the same element at risk, and the combined effects of cascading phenomena can strongly amplify the impact caused by single events in terms of extension of the affected area and damage level. The final impact on the territory can be significant and require to be carefully assessed in terms of emergency planning and management. This paper discusses from a theoretical point of view the modelling needs and the main issues to be taken into account in the development of simulation tools aiming to include cascading effects analyses to effectively support decision-makers in their preparedness and disaster mitigation strategies in the framework of emergency planning at local, national and international level. The model aims at developing cascading effects scenarios at different level of detail, depending on the availability of inventory/exposure data for the different categories of elements at risk and hazard/impact models for the various hazard sources. It has been developed within EU-FP7 SNOWBALL project (Lower the impact of aggravating factors in crisis situations thanks to adaptive foresight and decision-support tools, 2015–2017)

Uptake and effects of a mixture of widely used therapeutic drugs in Eruca sativa L. and Zea mays L. plants

Pharmaceutically active compounds (PACs) are continuously dispersed into the environment due to human and veterinary use, giving rise to their potential accumulation in edible plants. In this study, Eruca sativa L. and Zea mays L. were selected to determine the potential uptake and accumulation of eight different PACs (Salbutamol, Atenolol, Lincomycin, Cyclophosphamide, Carbamazepine, Bezafibrate, Ofloxacin and Ranitidine) designed for human use. To mimic environmental conditions, the plants were grown in pots and irrigated with water spiked with a mixture of PACs at concentrations found in Italian wastewaters and rivers. Moreover, 10 7 and 100 7 concentrations of these pharmaceuticals were also tested. The presence of the pharmaceuticals was tested in the edible parts of the plants, namely leaves for E. sativa and grains for Z. mays. Quantification was performed by liquid chromatography mass spectroscopy (LC/MS/MS). In the grains of 100 7 treated Z. mays, only atenolol, lincomycin and carbamazepine were above the limit of detection (LOD). At the same concentration in E. sativa plants the uptake of all PACs was >LOD. Lincomycin and oflaxacin were above the limit of quantitation in all conditions tested in E. sativa. The results suggest that uptake of some pharmaceuticals from the soil may indeed be a potential transport route to plants and that these environmental pollutants can reach different edible parts of the selected crops. Measurements of the concentrations of these pharmaceuticals in plant materials were used to model potential adult human exposure to these compounds. The results indicate that under the current experimental conditions, crops exposed to the selected pharmaceutical mixture would not have any negative effects on human health. Moreover, no significant differences in the growth of E. sativa or Z. mays plants irrigated with PAC-spiked vs. non-spiked water were observed

Patient organ and effective dose estimation in CT: comparison of four software applications

Background: Radiation dose in computed tomography (CT) has become a topic of high interest due to the increasing numbers of CT examinations performed worldwide. Hence, dose tracking and organ dose calculation software are increasingly used. We evaluated the organ dose variability associated with the use of different software applications or calculation methods. Methods: We tested four commercial software applications on CT protocols actually in use in our hospital: CT-Expo, NCICT, NCICTX, and Virtual Dose. We compared dose coefficients, estimated organ doses and effective doses obtained by the four software applications by varying exposure parameters. Our results were also compared with estimates reported by the software authors. Results: All four software applications showed dependence on tube voltage and volume CT dose index, while only CT-Expo was also dependent on other exposure parameters, in particular scanner model and pitch caused a variability till 50%. We found a disagreement between our results and those reported by the software authors (up to 600%), mainly due to a different extent of examined body regions. The relative range of the comparison of the four software applications was within 35% for most organs inside the scan region, but increased over the 100% for organs partially irradiated and outside the scan region. For effective doses, this variability was less evident (ranging from 9 to 36%). Conclusions: The two main sources of organ dose variability were the software application used and the scan region set. Dose estimate must be related to the process used for its calculation

Use of the Intermittent Abdominal Pressure Ventilation to guarantee speech in a tracheostomized Amyotrophic Lateral Sclerosis patient

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Workflow of Digital Field Mapping and Drone-Aided Survey for the identification and Characterization of Capable Faults: The Case of a Normal Fault System in the Monte Nerone Area (Northern Apennines, Italy)

Field work on the search and characterization of ground effects of a historical earthquake (i.e., the Cagli earthquake in 1781) was carried out using terrestrial and aerial digital tools. The method of capturing, organizing, storing, and elaborating digital data is described herein, proposing a possible workflow starting from pre-field project organization, through reiteration of field and intermediate laboratory work, to final interpretation and synthesis. The case of one of the most important seismic events in the area of the northern Umbria–Marche Apennines provided the opportunity to test the method with both postgraduate students and researchers. The main result of this work was the mapping of a capable normal fault system with a great number of observations, as well as a large amount of data, from difficult outcrop areas. A GIS map and a three-dimensional (3D) model, with the integration of subsurface data (i.e., seismic profiles and recent earthquake distribution information), allowed for a new interpretation of an extensional tectonic regime of this Apennines sector, similar to one of the southernmost areas of central Italy where recent earthquakes occurred on 2016

The Estimation of Cortical Activity for Brain-Computer Interface: Applications in a Domotic Context

In order to analyze whether the use of the cortical activity, estimated from noninvasive EEG recordings, could be useful to detect mental states related to the imagination of limb movements, we estimate cortical activity from high-resolution EEG recordings in a group of healthy subjects by using realistic head models. Such cortical activity was estimated in region of interest associated with the subject's Brodmann areas by using a depth-weighted minimum norm technique. Results showed that the use of the cortical-estimated activity instead of the unprocessed EEG improves the recognition of the mental states associated to the limb movement imagination in the group of normal subjects. The BCI methodology presented here has been used in a group of disabled patients in order to give them a suitable control of several electronic devices disposed in a three-room environment devoted to the neurorehabilitation. Four of six patients were able to control several electronic devices in this domotic context with the BCI system

SIR-C/X-SAR data calibration and ground truth campaign over the NASA-CB1 test-site

During the Space Shuttle Endeavour mission in October 1994, a remote-sensing campaign was carried out with the objectives of both radiometric and polarimetric calibration and ground truth data acquisition of bare soils. This paper presents the results obtained in the experiment. Polarimetric cross-talk and channel imbalance values, as well as radiometric calibration parameters, have been found to be within the science requirements for SAR images. Regarding ground truth measurements, a wide spread in the height rms values and correlation lengths has been observed, which has motivated a critical revisiting of surface parameters descriptors

Distinctive physiological muscle synergy patterns define the Box and Block Task execution as revealed by electromyographic features

Stroke survivors experience muscular pattern alterations of the upper limb that decrease their ability to perform daily-living activities. The Box and Block test (BBT) is widely used to assess the unilateral manual dexterity. Although BBT provides insights into functional performance, it returns limited information about the mechanisms contributing to the impaired movement. This study aims at exploring the BBT by means of muscle synergies analysis during the execution of BBT in a sample of 12 healthy participants with their dominant and non-dominant upper limb. Results revealed that: (i) the BBT can be described by 1 or 2 synergies; the number of synergies (ii) does not differ between dominant and non-dominant sides and (iii) varies considering each phase of the task; (iv) the transfer phase requires more synergies. Clinical Relevance— This preliminary study characterizes muscular synergies during the BBT task in order to establish normative patterns that could assist in understanding the neuromuscular demands and support future evaluations of stroke deficit