A topological approach to neural complexity

Considerable efforts in modern statistical physics is devoted to the study of networked systems. One of the most important example of them is the brain, which creates and continuously develops complex networks of correlated dynamics. An important quantity which captures fundamental aspects of brain network organization is the neural complexity C(X)introduced by Tononi et al. This work addresses the dependence of this measure on the topological features of a network in the case of gaussian stationary process. Both anlytical and numerical results show that the degree of complexity has a clear and simple meaning from a topological point of view. Moreover the analytical result offers a straightforward algorithm to compute the complexity than the standard one.Comment: 6 pages, 4 figure

Pláticas de Doctrina Christiana [Manuscrito]

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Neural detection of complex sound sequences in the absence of consciousness

Neural responses to violations of global regularities are thought to require consciousness. However, Tzovara et al. show that some comatose patients can also detect deviations in sequences composed of repeated groups of sounds, suggesting that the unconscious brain has a greater capacity to track sensory inputs than previously believe

The VIMOS-VLT Deep Survey: Dependence of galaxy clustering on stellar mass

We have investigated the dependence of galaxy clustering on their stellar mass at z~1, using the data from the VIMOS-VLT Deep Survey (VVDS). We have measured the projected two-point correlation function of galaxies, wp(rp) for a set of stellar mass selected samples at an effective redshift =0.85. We have control and quantify all effects on galaxy clustering due to the incompleteness of our low mass samples. We find that more massive galaxies are more clustered. When compared to similar results at z~0.1 in the SDSS, we observed no evolution of the projected correlation function for massive galaxies. These objects present a stronger linear bias at z~1 with respect to low mass galaxies. As expected, massive objects at high redshift are found in the highest pics of the dark matter density field.Comment: 4 pages, 2 figures, 43rd Rencontres de Moriond - March 15-22, 2008 - La Thuile (Val d'Aosta, Italy

IL MUSEO DELL’OSSERVATORIO VESUVIANO E IL SUO PUBBLICO. ANNI 2005 - 2009

The Vesuvius Observatory, first volcanological observatory in the world, was built in 1841 by King Ferdinand II of Bourbon. It is now the Naples section of the National Institute of Geophysics and Volcanology (INGV). Since its foundation it has been not only a reference point for national and international scientific community, but also a place of information and dissemination for the population in the field of research and monitoring of volcanic phenomena. Always museum activities, guided tours through the collections of scientific instruments, rocks and minerals have been carried out in it. Since 2000 scientific and historical collections located into the old building of Vesuvius Observatory have been organized in the exhibition "Vesuvius: 2000 years of observations", which describes the eruptive history of Somma-Vesuvius, with the aim of providing updated information about monitoring of active volcanoes, on eruptive phenomena and related hazards, educating the population of areas exposed to volcanic hazards. The museum path is targeted to public of any geographical origin and cultural background and could be considered a journey through the history of volcanology from the beginning until the present day. In the exhibition, Vesuvius is the backdrop to an exhibition in which purely scientific elements coexist with historical, archaeological, literary, artistic aspects, thanks to the support of images, documents such as the geological map of Henry James Johnston-Lavis and the book "Campi Flegrei" by William Hamilton, specimens of rocks and minerals and old scientific instruments, used in the past for monitoring volcanic activity, including the first electromagnetic seismograph made by Luigi Palmieri. The first part of this work is focussed on the description of the existing exhibition. Since 2000 the statistical survey of the public of the museum has been carried out through an evaluation procedure form. The findings relate to the monthly and annual attendance, geographical origin and kind of visitors. In the second part of this work results for the five years from 2005 to 2009 are described. The characterization of different audiences in the museum means that, from time to time, the path of the visit could be arranged according to the expectations and needs of visitors; in this context, the museum educator plays the delicate role of mediator, with accurate language, between the contents of the museum and those who interact with it

Prevalence of Sarcopenia in Knee Osteoarthritis: A Systematic Review and Meta-Analysis

An association between knee osteoarthritis (OA) and sarcopenia has been proposed, but the evidence is controversial, with the recent literature showing disparate results. Therefore, we aimed to perform a systematic review and meta-analysis to evaluate the prevalence of sarcopenia in knee OA patients compared to people not affected by this condition. We searched several databases until 22 February 2022. The data regarding prevalence were summarized using odds ratios (ORs) with their 95% confidence intervals (CIs). Among the 504 papers initially screened, 4 were included for a total of 7495 participants with a mean age of 68.4 years, who were mainly females (72.4%). The prevalence of sarcopenia in people with knee OA was 45.2%, whilst, in the controls, it was 31.2%. Pooling the data of the studies included that the prevalence of sarcopenia in knee OA was more than two times higher than in the control group (OR = 2.07; 95%CI: 1.43–3.00; I2 = 85%). This outcome did not suffer any publication bias. However, after removing an outlier study, the recalculated OR was 1.88. In conclusion, the presence of sarcopenia in knee OA patients was high, affecting one person in every two persons and was higher than in the control groups included

COVID-19 infection and rheumatoid arthritis: Faraway, so close!

The outbreak of the new coronavirus infections COVID-19 in December 2019 in China has quickly become a global health emergency. Given the lack of specific anti-viral therapies, the current management of severe acute respiratory syndrome coronaviruses (SARS-CoV-2) is mainly supportive, even though several compounds are now under investigation for the treatment of this life-threatening disease. COVID-19 pandemic is certainly conditioning the treatment strategy of a complex disorder as rheumatoid arthritis (RA), whose infectious risk is increased compared to the general population because of an overall impairment of immune system typical of autoimmune diseases combined with the iatrogenic effect generated by corticosteroids and immunosuppressive drugs. However, the increasing knowledge about the pathophysiology of SARS-CoV-2 infection is leading to consider some anti-rheumatic drugs as potential treatment options for the management of COVID-19. In this review we will critically analyse the evidences on either positive or negative effect of drugs commonly used to treat RA in this particular scenario, in order to optimize the current approach to RA patients