The impact of an extracurricular outdoor physical activity program on long-term memory in adolescent during COVID-19 pandemic

The present study examined the effects of an 8-week extracurricular outdoor physical activity program aimed to improve long-term memory performance in adolescent concerning the Covid-19 period. Participants were 40 schoolchildren (aged 16-17) who trained twice a week in aerobic exercise two hours per session, randomly assigned to participate in either an extracurricular outdoor physical activity program (EG; n = 20) or a waitlist control group (CG; n = 20). At baseline and after training we administered the Verbal Paired Associates (VPA-I) a subtest of the Wechsler Memory Scale – IV (WMS-IV, 2009), which represents one of the most widely used instruments for assessing explicit episodic memory performance. The results suggested that after 8-week aerobic exercise program students were able to increase their long-term memory, and that this capacity was more evident following physical activity that required greater cognitive involvement

Plyometric training on sand versus grass: Effects on sprinting, jumping, agility and balance in soccer players

Soccer is an intermittent high-intensity activity requiring explosive strength and power production by the neuromuscular system. Plyometric training is recognized as an effective method for improving both sprinting and jumping ability through the stretch-shortening cycle. The aim of this study was to compare the effects of plyometric training on sand versus a grass surface on sprinting, jumping, agility, balance ability in soccer players. Sixteen adult soccer players volunteered in the study and were randomly assigned to a plyometric training group performed on sand (PS, n = 8) or on grass (PG, n = 8). Both groups performed 7 weeks of plyometric training on two separate weekly sessions lasting about 1.5 hour. Five-, 10- and 20-meters sprint test, Sargent test and standing long jump test, Illynois Agility test and Stork test were administered to assess sprinting, jumping, agility and balance ability, respectively. After 7 weeks of intervention results showed significative improvements in PS group for sprinting (p < .05), for standing long jump test (p < .05) and for balance (p < .05). Small but not significant differences were found for the other variables. A 7-week plyometric training performed on sand showed improvements on sprinting, jumping and balance respect to the same training performed on grass surface in adult soccer players

Proposal for a Fitness Program in the School Setting during the COVID 19 Pandemic: Effects of an 8-Week CrossFit Program on Psychophysical Well-Being in Healthy Adolescents

Background: The Italian government promoted social distancing, in which the suspension of any social event, suspension of all activities practiced in gyms, sports centers and their closure was ordered. The social distancing in the school environment and the use of strategies to limit viral infection are not very compatible with group motor activity and team sports. The aim of this study is to verify the effectiveness of a CrossFit program in order to mitigate the deficits in fitness caused by COVID-19 prevention measures and to evaluate the effects on self-efficacy in a group of young adolescents. Methodsː 30 healthy participants were randomly allocated into an intervention group (IG) that performed the 8 weeks CrossFit training program or control group (CG). Physical fitness tests (i.e., Squat, push-up, lunge, and 20 m run) and psychological measures Regulatory Emotional Self-Efficacy scale (RESE) were performed at baseline and after 8 weeks. Resultsː After 8 weeks, the intervention group showed significant improvements for all fitness tests (p &lt; 0.0001). Additionally, higher scores for the RESE negative and positive (p &lt; 0.0001) scales were found in the intervention group. No statistical differences were found in the control group except for the push up test. Conclusionsː the 8-week CrossFit intervention program could positively affect the general physical well-being and improve the emotional perceived self-efficacy in healthy adolescents. View Full-Tex

The Relationship between Physical Activity, Physical Exercise, and Human Gut Microbiota in Healthy and Unhealthy Subjects: A Systematic Review

Several studies have been conducted to find at least an association between physical activity (PA)/ physical exercise (PE) and the possibility to modulate the gut microbiome (GM). However, the specific effects produced on the human GM by different types of PA/PE, different training modalities, and their age-related effects are not yet fully understood. Therefore, this systematic review aims to evaluate and summarize the current scientific evidence investigating the bi-directional relationship between PA/PE and the human GM, with a specific focus on the different types/variables of PA/PE and age-related effects, in healthy and unhealthy people. A systematic search was conducted across four databases (Web of Science, Medline (PubMed), Google Scholar, and Cochrane Library). Information was extracted using the populations, exposure, intervention, comparison, outcomes (PICOS) format. The Oxford Quality Scoring System Scale, the Risk of Bias in Non-Randomized Studies of Interventions (ROBINS-I) tool, and the JBI Critical Appraisal Checklist for Analytical Cross-Sectional Studies were used as a qualitative measure of the review. The protocol was registered in PROSPERO (code: CRD42022302725). The following data items were extracted: author, year of publication, study design, number and age of participants, type of PA/PE carried out, protocol/workload and diet assessment, duration of intervention, measurement tools used, and main outcomes. Two team authors reviewed 694 abstracts for inclusion and at the end of the screening process, only 76 full texts were analyzed. Lastly, only 25 research articles met the eligibility criteria. The synthesis of these findings suggests that GM diversity is associated with aerobic exercise contrary to resistance training; abundance of Prevotella genus seems to be correlated with training duration; no significant change in GM richness and diversity are detected when exercising according to the minimum dose recommended by the World Health Organizations; intense and prolonged PE can induce a higher abundance of pro-inflammatory bacteria; PA does not lead to significant GM α/β-diversity in elderly people (60+ years). The heterogeneity of the training parameters used in the studies, diet control, and different sequencing methods are the main confounders. Thus, this systematic review can provide an in-depth overview of the relationship between PA/PE and the human intestinal microbiota and, at the same time, provide indications from the athletic and health perspective

Pre- and Post-Activity Anxiety for Sustainable Rafting

This study aimed to (i) analyze the levels of state-anxiety of rafting customers, before and after the activity; and (ii) characterize the levels of trait-anxiety and the amount of physical activity performed weekly by clients of a rafting activity. The sample had 100 subjects of a nature sports company, in the rafting activity, with a mean age of 33.27 ± 10.10 years, with 44% female and 56% male participants. They were evaluated in two moments M1 (pre-activity) and M2 (post-activity). In M1, the STAI—State-Anxiety questionnaire and the IPAQ—International Physical Activity Questionnaire (short version) were applied. In M2, the STAI Form 1 State-Anxiety questionnaire was applied again, followed by the STAI trait-anxiety. The results showed no correlation between the amount of weekly physical activity and levels of trait-anxiety (rho(100) = −0.144; p-value = 0.152), thus not corroborating with the existing literature. Regarding state-anxiety, we found that in 55% of cases, it decreased with the practice of rafting, which suggests that the practice may have an anxiolytic effect and promote the well-being and relaxation of participants promoting, in this way, the sustainability of the rafting activity

SARS-CoV-2 pneumonia and Eisenmenger’s Syndrome: doubling the challenge

Eisenmenger’s syndrome (ES) is the most severe phenotype of pulmonary arterial hypertension (PAH) secondary to congenital heart disease. In these cases, a significant systemic-to-pulmonary (left-to-right) shunting triggers the development of pulmonary vascular disease (PVD) and pulmonary hypertension. In cases of acute hypoxemic respiratory failure in patients with ES, high flow nasal cannula (HFNC) oxygen therapy should be considered as a first-line approach in order to avoid pulmonary complications and right ventricular overload related to positive pressure ventilation. Here, we report a case of HFNC use in a patient with COVID-19 infection and ES

Are sEMG, velocity and power influenced by athletes’ fixation in paralympic powerlifting?

The bench press is performed in parapowerlifting with the back, shoulders, buttocks, legs and heels extended over the bench, and the use of straps to secure the athlete to the bench is optional. Thus, the study evaluated muscle activation, surface electromyography (sEMG), maximum velocity (MaxV) and mean propulsive velocity (MPV), and power in paralympic powerlifting athletes under conditions tied or untied to the bench. Fifteen experienced Paralympic powerlifting male athletes (22.27 10.30years, 78.5 21.6kg)tookpartintheresearch. The sEMGmeasurementwasperformed in the sternal portion of the pectoralis major (PMES), anterior deltoid (AD), long head of the triceps brachii (TRI) and clavicular portion of the pectoralis major (PMCL). The MaxV, MPV and power were evaluated using an encoder. Loads of 40%, 60%, 80% and 100% 1RM were analyzed under untied and tied conditions. No differences were found in muscle activation between the tied and untied conditions; however, sEMG showed differences in the untied condition between AD and TRI (F (3112) = 4.484; p = 0.005) in the 100% 1RM load, between PMCL and AD (F (3112) = 3.743; p = 0.013) in 60%1RMloadandinthetied condition, between the PMES and the AD (F (3112) = 4.067; p = 0.009). There were differences in MaxV (F (3112) = 213.3; p < 0.001), and MPV (F (3112) = 248.2; p < 0.001), between all loads in the tied and untied condition. In power, the load of 100% 1RM differed from all other relative loads (F (3112) = 36.54; p < 0.001) in both conditions. The tied condition seems to favor muscle activation, sEMG, and velocity over the untied condition.9E1A-F9DD-3EB8 | Filipe Manuel ClementeN/

Prognostic Factors for Overall Survival In Chronic Myeloid Leukemia Patients: A Multicentric Cohort Study by the Italian CML GIMEMA Network

An observational prospective study was conducted by the CML Italian network to analyze the role of baseline patient characteristics and first line treatments on overall survival and CML-related mortality in 1206 newly diagnosed CML patients, 608 treated with imatinib (IMA) and 598 with 2nd generation tyrosine kinase inhibitors (2GTKI). IMA-treated patients were much older (median age 69 years, IQR 58-77) than the 2GTKI group (52, IQR 41-63) and had more comorbidities. Estimated 4-year overall survival of the entire cohort was 89% (95%CI 85.9-91.4). Overall, 73 patients (6.1%) died: 17 (2.8%) in the 2GTKI vs 56 (9.2%) in the IMA cohort (adjusted HR=0.50; 95% CI=0.26-0.94), but no differences were detected for CML-related mortality (10 (1.7%) vs 11 (1.8%) in the 2GTKIs vs IMA cohort (sHR=1.61; 0.52-4.96). The ELTS score was associated to CML mortality (high risk vs low, HR=9.67; 95%CI 2.94-31.74; p&lt;0.001), while age (per year, HR=1.03; 95%CI 1.00-1.06; p=0.064), CCI (4-5 vs 2, HR=5.22; 95%CI 2.56-10.65; p&lt;0.001), ELTS score (high risk vs low, HR=3.11; 95%CI 1.52-6.35, p=0.002) and 2GTKI vs IMA (HR=0.26; 95%CI 0.10-0.65, p=0.004) were associated to an increased risk of non-related CML mortality. The ELTS score showed a better discriminant ability than the Sokal score in all comparisons

Clinical Features, Cardiovascular Risk Profile, and Therapeutic Trajectories of Patients with Type 2 Diabetes Candidate for Oral Semaglutide Therapy in the Italian Specialist Care

Introduction: This study aimed to address therapeutic inertia in the management of type 2 diabetes (T2D) by investigating the potential of early treatment with oral semaglutide. Methods: A cross-sectional survey was conducted between October 2021 and April 2022 among specialists treating individuals with T2D. A scientific committee designed a data collection form covering demographics, cardiovascular risk, glucose control metrics, ongoing therapies, and physician judgments on treatment appropriateness. Participants completed anonymous patient questionnaires reflecting routine clinical encounters. The preferred therapeutic regimen for each patient was also identified. Results: The analysis was conducted on 4449 patients initiating oral semaglutide. The population had a relatively short disease duration (42%  60% of patients, and more often than sitagliptin or empagliflozin. Conclusion: The study supports the potential of early implementation of oral semaglutide as a strategy to overcome therapeutic inertia and enhance T2D management