A scheme for the identification of organic acids insoluble in cold water

Thesis (M.A.)--Boston University PLEASE NOTE: author has misnumbered thesis pages. Two different pages are numbered 4; likewise 53. Pages 54 and 55 appear to be missing from the thesis; our determination is that this is the result of misnumbering by the author, and no substantive content is actually missing. If you are able to determine otherwise, please contact us

Oral History Interview: Margaret Gault Whitehair Day

This interview is one of series conducted concerning the Oral History of Appalachia. Mrs. Margaret Gault Whitehair Day was born in Holden, WV in 1913. She discusses: her childhood in Eastern Kentucky, including school, neighbors, clothing they wore, and games they played; her first encounters with modern amenities such as indoor plumbing; mining towns; candy; food; some discussion of churches; working at General Electric in Louisville, KY; her family; and other topics.https://mds.marshall.edu/oral_history/1478/thumbnail.jp

A Test for Penicillins on Chromatograms and in Spot Tests

Author Institution: Department of Chemistry, University of Cincinnati, Cincinnati, Ohio 4522

Go low or say No to aggressive systolic BP goals?

"Go low" or say "No" to aggressive systolic BP goals? The SPRINT trial demonstrated the benefits -- and risks -- of reaching a systolic target <120 mm Hg in non-diabetic patients at high risk for CV events. Here's who might benefit. Practice changer: Consider treating non-diabetic patients age greater than or equal to 50 years to a systolic blood pressure (SBP) target <120 mm Hg as compared to <140 mm Hg when the benefits -- lower rates of fatal and nonfatal cardiovascular (CV) events and death from any cause -- are likely to outweigh the risks from possible additional medication

Foundations of peace and harmony in families and communities: Insights from a TRUST, LEARN and CARE (TLC) framework

In a world riven by conflict, violent extremism and sectarian animosities, peace is in short supply. Promoting peace is, however, central to the great traditions of faith, including Islam. Contrary to their core precepts, fear, hatred and envy drive an evil mis-construal of the core tenets of these religions; the antithesis of their fundamental commitment to the promotion of tolerance, care and compassion.  Contemporary events defy comprehension and highlight the urgent need to find ways, especially within families and the communities in which they live, to counter radicalisation. Families, after all, ought to be key contexts for promoting dialogue, understanding and peace, consistent with the precepts of the Abrahamic religious traditions, and the Qur’anic focus on families that sees them as the forum for fulfilling the basic Islamic foundations of peace. Strong families build capable, caring and compassionate communities. The present paper briefly outlines a three-element model that might be usefully applied to better understand the processes of development of prosocial attitudes, beliefs and behaviours that are so vital for peaceful, constructive and compassionate co-existence; attributes that are so vitally needed in an increasingly multi-cultural, multi-ethnic and multi-faith world.  The elements are encapsulated in three conceptually linked acronyms: TRUST; LEARN; CARE or TLC. The trust, learn, care (TLC) framework has been developed from key principles in the new discipline of family studies. Global changes present many challenges for families and communities. This article concludes that a peaceful and harmonious future will be built on the foundations for dialogue and understanding that start in families and communities. Trust and tolerance, learning and teaching, caring and compassion are at the heart of acceptance of diversity, growth of understanding and promotion of respect for cultures, religions and beliefs

An Experiment In Modular Transport Protocol Design And Its Importance For Multicast Protocols

Report describes the results of an experiment exploring new architectural directions in the design of communication protocols

A critical edition of The Privity of the Passion and The Lyrical Meditations.

Available from British Library Document Supply Centre- DSC:DX97519 / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

Impact of standalone and embedded telephone triage systems on after hours primary medical care service utilisation and mix in Australia

BACKGROUND: The Australian government sponsored five local trials aimed at addressing problems in after hours (AH) primary medical care (PMC). The study's objective was to determine if the four trials, where telephone triage was the sole innovation, led to a reduction in AH service utilisation and change in service mix towards AH GP clinics. Changes in utilisation and mix of AH GP clinic and home visits, ED and ambulance use were monitored in the trial areas, and in a national sample to adjust for the effects of secular trend. Pre- and post-trial telephone surveys of two separate random samples of approximately 350 AH PMC user households in each area were conducted. RESULTS: Some types of AH PMC use became more frequent in both of the standalone services using nurse-administered proprietary call centre software, which were aimed at better addressing population need (Statewide call centre; Regional call centre). Service use overall (95%CI: 1.03–1.83) and GP clinic use (95%CI: 1.07–2.00) increased in the metro area of the Statewide call centre and in GP clinic (95%CI: 1.04–2.14) and home visits (95%CI: 1.03–3.91) in the non-metro area of the Regional call centre. Service mix only changed in the non-metro area of the Regional call centre with increased contact in GP home visits (95%CI: 1.02–4.38). Levels of use remained unchanged in both embedded services using other than proprietary software, which were established to support the GP workforce (Deputising service; Local triage centre). Service mix only changed in the Deputising service with a change away from AH GP clinics in both contact (95%CI: 0.39–0.97) and frequency (95% CI: -2.12 – -0.7). CONCLUSION: Bearing in mind limitations in estimating AH PMC utilisation levels and mix, it is concluded that the impacts of telephone triage were generally smaller in Australia than reported elsewhere. There were different impacts on levels of service utilisation and service mix in standalone call centres and embedded services. Impacts of telephone triage on service utilisation and mix are influenced by the type of telephone triage offered, the goals of the agency providing the service, as well as local factors. (345 words

Genetic Engineering and Therapy for Inherited and Acquired Cardiomyopathies

The cardiac myofilaments consist of a highly ordered assembly of proteins that collectively generate force in a calcium-dependent manner. Defects in myofilament function and its regulation have been implicated in various forms of acquired and inherited human heart disease. For example, during cardiac ischemia, cardiac myocyte contractile performance is dramatically downregulated due in part to a reduced sensitivity of the myofilaments to calcium under acidic pH conditions. Over the last several years, the thin filament regulatory protein, troponin I, has been identified as an important mediator of this response. Mutations in troponin I and other sarcomere genes are also linked to several distinct inherited cardiomyopathic phenotypes, including hypertrophic, dilated, and restrictive cardiomyopathies. With the cardiac sarcomere emerging as a central player for such a diverse array of human heart diseases, genetic-based strategies that target the myofilament will likely have broad therapeutic potential. The development of safe vector systems for efficient gene delivery will be a critical hurdle to overcome before these types of therapies can be successfully applied. Nonetheless, studies focusing on the principles of acute genetic engineering of the sarcomere hold value as they lay the essential foundation on which to build potential gene-based therapies for heart disease.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/72315/1/annals.1380.033.pd