Seronegative spondyloarthropathies : a review : part I: classification and differential diagnosis

The seronegative spondyloarthropathies comprise a group of non-rheumatoid disorders with similar clinical, laboratory and genetic features. Recognition of new clinical features has supported the notion that they all form part of a clinical spectrum. These features and the classification of the seronegative spondyloarthropathies are discussed in the review.peer-reviewe

Seronegative spondyloarthropathies : a review : part II: genetics and pathogenesis

In none of the spondyloarthropathies is the pathogenesis well understood. Much of the investigation into the aetio-pathogenesis of these diseases has focused on the association with HLA-B27 and the known triggering potential of certain infectious agents. In this article the author describes that the HLA linked genes which is subdivided into three groups, class I, class II and class III, which are structurally and functionally distinct from each other.peer-reviewe

The realizations of final 's' in Caracas Spanish : An experimental study.

SIGLEAvailable from British Library Document Supply Centre- DSC:D86431 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

Celebrating ACRL\u27s 75th Anniversary: Librarians\u27 Roles in Changing Times

In this guest editorial, Dawes shares his view on the changing role of librarians

The Path to Library Leadership: The Importance of a Leadership Plan

Preparing leaders in the library profession is by no means a new phenomenon. However, as one looks at the number of leadership training and development programs, institutes, workshops, and conferences, you might begin to ask the question, “where are all the people who participated in these programs?” Top Takeaways in this Chapter •Develop a personal mission statement and refer to it often •Build relationships with mentors—formal and informal •Know your limitations •Continue to learn and gro

Minnesota Institute for Early Career Librarians from Traditionally Underrepresented Groups

The Minnesota Institute for Early Career Librarians from Traditionally Underrepresented Groups (MNTIEL, or the Minnesota Institute) is offered every two years for librarians with less than five years’ professional library experience and is intended to provide an “opportunity to learn about leadership and organizational behavior in institutions of higher education. This chapter provides an overview of the program highlighting some benefits and potential shortfalls

New Times, New Roles, New Structures

Slides from the Closing Keynote presentation at the Wisconsin Association of Academic Librarians (WAAL) Annual Conference, April 2015. The talk was about the changing roles of librarians that have come about as a result of changing needs of faculty, scholars and researchers. Some libraries have also modified their structures to better carry out these new roles.https://openscholarship.wustl.edu/lib_present/1010/thumbnail.jp

Pressure Shifts in High-Precision Hydrogen Spectroscopy: I. Long-Range Atom-Atom and Atom-Molecule Interactions

We study the theoretical foundations for the pressure shifts in high-precision atomic beam spectrosopy of hydrogen, with a particular emphasis on transitions involving higher excited P states. In particular, the long-range interaction of an excited hydrogen atom in a 4P state with a ground-state and metastable hydrogen atom is studied, with a full resolution of the hyperfine structure. It is found that the full inclusion of the 4P_1/2 and 4P_3/2 manifolds becomes necessary in order to obtain reliable theoretical predictions, because the 1S ground state hyperfine frequency is commensurate with the 4P fine-structure splitting. An even more complex problem is encountered in the case of the 4P-2S interaction, where the inclusion of quasi-degenerate 4S-2P_1/2 state becomes necessary in view of the dipole couplings induced by the van der Waals Hamiltonian. Matrices of dimension up to 40 have to be treated despite all efforts to reduce the problem to irreducible submanifolds within the quasi-degenerate basis. We focus on the phenomenologically important second-order van der Waals shifts, proportional to 1/R^6 where R is the interatomic distance, and obtain results with full resolution of the hyperfine structure. The magnitude of van der Waals coefficients for hydrogen atom-atom collisions involving excited P states is drastically enhanced due to energetic quasi-degeneracy; we find no such enhancement for atom-molecule collisions involving atomic nP states, even if the complex molecular spectrum involving ro-vibrational levels requires a deeper analysis.Comment: 32 pages; 2 figures; this is part 1 of a series of two papers; part 1 carries article number 075005, while part 2 carries article number 075006 in the journal (online journal version has been rectified). arXiv admin note: text overlap with arXiv:1711.1003

Insight into High-quality Aerodynamic Design Spaces through Multi-objective Optimization

An approach to support the computational aerodynamic design process is presented and demonstrated through the application of a novel multi-objective variant of the Tabu Search optimization algorithm for continuous problems to the aerodynamic design optimization of turbomachinery blades. The aim is to improve the performance of a specific stage and ultimately of the whole engine. The integrated system developed for this purpose is described. This combines the optimizer with an existing geometry parameterization scheme and a well- established CFD package. The system’s performance is illustrated through case studies – one two-dimensional, one three-dimensional – in which flow characteristics important to the overall performance of turbomachinery blades are optimized. By showing the designer the trade-off surfaces between the competing objectives, this approach provides considerable insight into the design space under consideration and presents the designer with a range of different Pareto-optimal designs for further consideration. Special emphasis is given to the dimensionality in objective function space of the optimization problem, which seeks designs that perform well for a range of flow performance metrics. The resulting compressor blades achieve their high performance by exploiting complicated physical mechanisms successfully identified through the design process. The system can readily be run on parallel computers, substantially reducing wall-clock run times – a significant benefit when tackling computationally demanding design problems. Overall optimal performance is offered by compromise designs on the Pareto trade-off surface revealed through a true multi-objective design optimization test case. Bearing in mind the continuing rapid advances in computing power and the benefits discussed, this approach brings the adoption of such techniques in real-world engineering design practice a ste

The Asian red seaweed Grateloupia turuturu (Rhodophyta) invades the Gulf of Maine

We report the invasion of the Gulf of Maine, in the northwest Atlantic Ocean, by the largest red seaweed in the world, the Asian Grateloupia turuturu. First detected in 1994 in Narragansett Bay, Rhode Island, south of Cape Cod, this alga had expanded its range in the following years only over to Long Island and into Long Island Sound. In July 2007 we found Grateloupia in the Cape Cod Canal and as far north (east) as Boston, Massachusetts, establishing its presence in the Gulf of Maine. Grateloupia can be invasive and may be capable of disrupting low intertidal and shallow subtidal seaweeds. The plant\u27s broad physiological tolerances suggest that it will be able to expand possibly as far north as the Bay of Fundy. We predict its continued spread in North America and around the world, noting that its arrival in the major international port of Boston may now launch G. turuturu on to new global shipping corridors