Successfully translating conservation research into practice and policy: concluding thoughts

In the Anthropocene, when our environment is changing rapidly and the windows of opportunity for action to prevent further biodiversity loss are narrow, conservation researchers are increasingly encouraged to think and operate beyond the traditional approaches of producing peer-reviewed papers and presenting results to other members of the research community. Indeed, the perception that researchers belong in their ivory tower, from which they deliver evidence for others to interpret, disseminate and use in decision-making, is thankfully now widely recognised as outdated. The rise of fake news, a deliberate lack of consideration for scientific evidence, and changes to the ways of assessing the value of researchers’ work probably all play a role in supporting this shift in perception. Moreover, for many researchers, the prospect of their work ‘making a difference’ and having an impact on wider society is at least as great a motivation for doing research as generating new knowledge, however interesting that may be

Making a difference in conservation: linking science and policy

amie Gundry’s dramatic image of a white-tailed eagle (Haliaeetus albicilla) on the cover of this book reflects the twisting changes in fortune experienced by this species, with a revival that can be attributed to a successful interplay of science, policy and practice. White-tailed eagles were historically much more widely distributed than they are today (Yalden, 2007), once breeding across much of Europe, but by the early twentieth century the species was extinct across much of western and southern Europe. The main cause of its decline was persecution by farmers and shepherds, who considered the eagles a threat to their livestock, but, along with other raptors, white-tailed eagles were also seriously affected by DDT in the 1960s and 1970s, which had disastrous effects on the breeding success of remaining populations

Comments on Condensates in Non-Supersymmetric Orbifold Field Theories

Non-supersymmetric orbifolds of N=1 super Yang-Mills theories are conjectured to inherit properties from their supersymmetric parent. We examine this conjecture by compactifying the Z_2 orbifold theories on a spatial circle of radius R. We point out that when the orbifold theory lies in the weakly coupled vacuum of its parent, fractional instantons do give rise to the conjectured condensate of bi-fundamental fermions. Unfortunately, we show that quantum effects render this vacuum unstable through the generation of twisted operators. In the true vacuum state, no fermion condensate forms. Thus, in contrast to super Yang-Mills, the compactified orbifold theory undergoes a chiral phase transition as R is varied.Comment: 10 Pages. Added clarifying comments, computational steps and a nice pretty pictur

PROFIT: a new alternative for emission-line PROfile FITting

I briefly describe a simple routine for emission-line profiles fitting by Gaussian curves or Gauss-Hermite series. The PROFIT (line-PROfile FITting) routine represent a new alternative for use in fits data cubes, as those from Integral Field Spectroscopy or Fabry-Perot Interferometry, and may be useful to better study the emission-line flux distributions and gas kinematics in distinct astrophysical objects, such as the central regions of galaxies and star forming regions. The PROFIT routine is written in IDL language and is available at http://www.ufsm.br/rogemar/software.html. The PROFIT routine was used to fit the [Fe II]1.257um emission-line profiles for about 1800 spectra of the inner 350 pc of the Seyfert galaxy Mrk1066 obtained with Gemini NIFS and shows that the line profiles are better reproduced by Gauss-Hermite series than by the commonly used Gaussian curves. The two-dimensional map of the h_3 Gauss-Hermite moment shows its highest absolute values in regions close to the edge of the radio structure. These high values may be originated in an biconical outflowing gas associated with the radio jet - previously observed in the optical [O III] emission. The analysis of this kinematic component indicates that the radio jet leaves the center of the galaxy with the north-west side slightly oriented towards us and the south-east side away from us, being partially hidden by the disc of the galaxy.Comment: Accepted for publication Astrophysics & Space Science - 7 pges; 4 Fig

A motif-based approach to network epidemics

Networks have become an indispensable tool in modelling infectious diseases, with the structure of epidemiologically relevant contacts known to affect both the dynamics of the infection process and the efficacy of intervention strategies. One of the key reasons for this is the presence of clustering in contact networks, which is typically analysed in terms of prevalence of triangles in the network. We present a more general approach, based on the prevalence of different four-motifs, in the context of ODE approximations to network dynamics. This is shown to outperform existing models for a range of small world networks

Rapid destruction of protoplanetary discs due to external photoevaporation in star-forming regions

We analyse N-body simulations of star-forming regions to investigate the effects of external far- and extreme-ultraviolet photoevaporation from massive stars on protoplanetary discs. By varying the initial conditions of simulated star-forming regions, such as the spatial distribution, net bulk motion (virial ratio), and density, we investigate which parameters most affect the rate at which discs are dispersed due to external photoevaporation. We find that disc dispersal due to external photoevaporation is faster in highly substructured star-forming regions than in smooth and centrally concentrated regions. Subvirial star-forming regions undergoing collapse also show higher rates of disc dispersal than regions that are in virial equilibrium or are expanding. In moderately dense (∼100 M⊙ pc−3) regions, half of all protoplanetary discs with radii ≥100 au are photoevaporated within 1 Myr, three times faster than is currently suggested by observational studies. Discs in lower density star-forming regions (∼10 M⊙ pc−3) survive for longer, but half are still dispersed on short time-scales (∼2 Myr). This demonstrates that the initial conditions of the star-forming regions will greatly impact the evolution and lifetime of protoplanetary discs. These results also imply that either gas giant planet formation is extremely rapid and occurs before the gas component of discs is  evaporated, or gas giants only form in low-density star-forming regions where no massive stars are present to photoevaporate gas from protoplanetary discs

Effect of Education on Myopia: Evidence from the United Kingdom ROSLA 1972 Reform

YesCross-sectional and longitudinal studies have consistently reported an association between education and myopia. However, conventional observational studies are at risk of bias due to confounding by factors such as socioeconomic position and parental educational attainment. The current study aimed to estimate the causal effect of education on refractive error using regression discontinuity analysis. Methods: Regression discontinuity analysis was applied to assess the influence on refractive error of the raising of the school leaving age (ROSLA) from 15 to 16 years introduced in England and Wales in 1972. For comparison, a conventional ordinary least squares (OLS) analysis was performed. The analysis sample comprised 21,548 UK Biobank participants born in a nine-year interval centered on September 1957, the date of birth of those first affected by ROSLA. Results: In OLS analysis, the ROSLA 1972 reform was associated with a −0.29 D (95% confidence interval [CI]: −0.36 to −0.21, P < 0.001) more negative refractive error. In other words, the refractive error of the study sample became more negative by −0.29 D during the transition from a minimum school leaving age of 15 to 16 years of age. Regression discontinuity analysis estimated the causal effect of the ROSLA 1972 reform on refractive error as −0.77 D (95% CI: −1.53 to −0.02, P = 0.04). Conclusions: Additional compulsory schooling due to the ROSLA 1972 reform was associated with a more negative refractive error, providing additional support for a causal relationship between education and myopia.Global Education program of the Russian Federation government (DP) and an NIHR Senior Research Fellowship award SRF-2015-08-005 (CW), The Department for Health through an award made by the NIHR to the Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust, and UCL Institute of Ophthalmology, London, United Kingdom (grant no. BRC2_009). Additional support was provided by The Special Trustees of Moorfields Eye Hospital, London, United Kingdom (grant no. ST 12 09

Functional polymorphism in ABCA1 influences age of symptom onset in coronary artery disease patients

ATP-binding-cassette-transporter-A1 (ABCA1) plays a pivotal role in intracellular cholesterol removal, exerting a protective effect against atherosclerosis. ABCA1 gene severe mutations underlie Tangier disease, a rare Mendelian disorder that can lead to premature coronary artery disease (CAD), with age of CAD onset being two decades earlier in mutant homozygotes and one decade earlier in heterozygotes than in mutation non-carriers. It is unknown whether common polymorphisms in ABCA1 could influence age of symptom onset of CAD in the general population. We examined common promoter and non-synonymous coding polymorphisms in relation to age of symptom onset in a group of CAD patients (n = 1164), and also carried out in vitro assays to test effects of the promoter variations on ABCA1 promoter transcriptional activity and effects of the coding variations on ABCA1 function in mediating cellular cholesterol efflux. Age of symptom onset was found to be associated with the promoter − 407G > C polymorphism, being 2.82 years higher in C allele homozygotes than in G allele homozygotes and intermediate in heterozygotes (61.54, 59.79 and 58.72 years, respectively; P = 0.002). In agreement, patients carrying ABCA1 haplotypes containing the −407C allele had higher age of symptom onset. Patients of the G/G or G/C genotype of the −407G > C polymorphism had significant coronary artery stenosis (>75%) at a younger age than those of the C/C genotype (P = 0.003). Reporter gene assays showed that ABCA1 haplotypes bearing the −407C allele had higher promoter activity than haplotypes with the −407G allele. Functional analyses of the coding polymorphisms showed an effect of the V825I substitution on ABCA1 function, with the 825I variant having higher activity in mediating cholesterol efflux than the wild-type (825V). A trend towards higher symptom onset age in 825I allele carriers was observed. The data indicate an influence of common ABCA1 functional polymorphisms on age of symptom onset in CAD patient

Single-electron transport driven by surface acoustic waves: moving quantum dots versus short barriers

We have investigated the response of the acoustoelectric current driven by a surface-acoustic wave through a quantum point contact in the closed-channel regime. Under proper conditions, the current develops plateaus at integer multiples of ef when the frequency f of the surface-acoustic wave or the gate voltage Vg of the point contact is varied. A pronounced 1.1 MHz beat period of the current indicates that the interference of the surface-acoustic wave with reflected waves matters. This is supported by the results obtained after a second independent beam of surface-acoustic wave was added, traveling in opposite direction. We have found that two sub-intervals can be distinguished within the 1.1 MHz modulation period, where two different sets of plateaus dominate the acoustoelectric-current versus gate-voltage characteristics. In some cases, both types of quantized steps appeared simultaneously, though at different current values, as if they were superposed on each other. Their presence could result from two independent quantization mechanisms for the acoustoelectric current. We point out that short potential barriers determining the properties of our nominally long constrictions could lead to an additional quantization mechanism, independent from those described in the standard model of 'moving quantum dots'.Comment: 25 pages, 12 figures, to be published in a special issue of J. Low Temp. Phys. in honour of Prof. F. Pobel

The Moduli Space of BPS Domain Walls

N=2 SQED with several flavors admits multiple, static BPS domain wall solutions. We determine the explicit two-kink metric and examine the dynamics of colliding domain walls. The multi-kink metric has a toric Kahler structure and we reduce the Kahler potential to quadrature. In the second part of this paper, we consider semi-local vortices compactified on circle. We argue that, in the presence of a suitable Wilson line, the vortices separate into domain wall constituents. These play the role of fractional instantons in two-dimensional gauge theories and sigma-models.Comment: 16 pages, LaTex, 2 figures; factors of zeta corrected, meaning of cross-terms elucidated, further clarifying comments; (more) references adde