5,392 research outputs found
Induced growth of phytoplankton using two fertilizers (NPK and agrolyser) under laboratory conditions
An investigation was carried out on the ability of two types of fertilizer; agrolyser micronutrient and NPK (nitrogen, phosphorus, potassium)-macronutrient in inducing phytoplankton growth for sixteen days under laboratory conditions. The parameters studied were abundance, species diversity and occurrence of the phytoplankton. Twelve 14 L plastics tanks labeled A, B, C and D was used. Each letter represented a fertilizer treatment (three replicates): A, 0.27 g agrolyser; B, 200 g NPK; C, 200 g agrolyser + 0.27 g NPK; and D which is the control. Before the application of these fertilizers, water samples were taken for phytoplankton analyses using 250 ml wide mouth plastic containers. All the tanks were allowed to be naturally inoculated for 3 days. Samples were collected for phytoplankton and physicochemical parameters at an interval of 3 days except temperature which was measured twice daily (morning and evening). A total of 1244 phytoplankton made up of 20 species, belonging to three families: Bacillariophyceae (diatoms), Cyanophyceae (blue-green algae) and Euglenophyceae (euglenophytes) were observed. Out of these algae, tanks C had 51.7%, B 33.2%, A 10.6% and D 4.5% phytoplankters. In the various groups of tanks, the orders of abundance, species diversity and percentage distribution of species of algae were C>B>A>D, C>B>A=D and C>B>D>A, respectively. This paper intends to provide preliminary information to fish farmers that agrolyser should be combined with a macronutrient fertilizer for better fertilization of pond.Keywords: Induced growth, phytoplankton, fertilizer, NPK, agrolyse
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Inhomogeneous reionization models in cosmological hydrodynamical simulations
In this work we present a new hybrid method to simulate the thermal effects of reionization in cosmological hydrodynamical simulations. The method improves upon the standard approach used in simulations of the intergalactic medium (IGM) and galaxy formation without a significant increase in the computational cost, thereby allowing for efficient exploration of the parameter space. The method uses a small set of phenomenological input parameters, and combines a seminumerical reionization model to solve for the topology of reionization with an approximate model of how reionization heats the IGM, using the massively parallel Nyx hydrodynamics code which is specifically designed to solve for the structure of diffuse IGM gas. We have produced several medium-scale, high-resolution simulations (20483, Lbox = 40 Mpc h-1) with various instantaneous and inhomogeneous reionization models that use this new methodology. We study the IGM thermal properties of these models and find that large-scale temperature fluctuations extend well beyond the end of reionization. By analysing the 1D flux power spectrum of these models, we find up to {\sim } 50{{\\rm per\cent}} differences in the large-scale properties (low modes, k ≲0.01 s km-1) of the post-reionization power spectrum as a result of the thermal fluctuations. We show that these differences could allow one to distinguish between different reionization scenarios with existing Lyα forest measurements. Finally, we explore the differences in the small-scale cut-off of the power spectrum, finding that, for the same heat input, models show very good agreement provided that the reionization redshift of the instantaneous reionization model occurs at the midpoint of the inhomogeneous model
Clinical pharmacokinetics and dose recommendations for posaconazole gastroresistant tablets in children with cystic fibrosis.
Objectives: To investigate the population pharmacokinetics of posaconazole gastroresistant tablets in children with cystic fibrosis (CF) and perform simulations to recommend optimal doses.
Patients and methods: Children from a paediatric CF centre who had received posaconazole tablets and underwent therapeutic drug monitoring were identified from pharmacy records. Relevant clinical data were collated from case notes and electronic patient records and used to develop an allometrically scaled population pharmacokinetic model. A stepwise covariate model-building exercise evaluated the influence of interacting medicines and liver function.
Results: One hundred posaconazole serum concentrations were collected from 37 children with a median age of 14 years (range 7–17). Posaconazole pharmacokinetics were adequately described by a one-compartment model with inter-individual variability on clearance. Dose simulations demonstrated a 77%–83% probability of attaining a trough target of 1 mg/L with a dose of 300 mg every 12 h for two doses then 300 mg once daily (OD) in children aged 6–11 years; and 86%–88% with a dose of 400 mg every 12 h for two doses then 400 mg OD in adolescents aged 12–17 years. This dose scheme also yielded a 90% probability of achieving an AUC of 30 mg·h/L. AUC and trough concentration were highly correlated (r2 = 0.98). Simulations showed that trough concentrations of >0.75 mg/L would exceed an AUC of 30 mg·h/L in 90% of patients.
Conclusions: A starting dose of 300 mg OD in those aged 6–11 years and 400 mg OD in those aged 12–17 years (following loading doses) yields a 90% probability of attaining an AUC of 30 mg·h/L
Neutralino dark matter vs galaxy formation
Neutralino dark matter may be incompatible with current cold dark matter
models with cuspy dark halos, because excessive synchrotron radiation may
originate from neutralino annihilations close to the black hole at the galactic
center.Comment: 6 pages, 3 figures, talk given at "Sources and detection of dark
matter in the Universe", Marina del Rey, CA, February 23-25, 200
Expression of Interest: The Atmospheric Neutrino Neutron Interaction Experiment (ANNIE)
Submitted for the January 2014 Fermilab Physics Advisory Committee meetingSubmitted for the January 2014 Fermilab Physics Advisory Committee meetingSubmitted for the January 2014 Fermilab Physics Advisory Committee meetingSubmitted for the January 2014 Fermilab Physics Advisory Committee meetingNeutron tagging in Gadolinium-doped water may play a significant role in reducing backgrounds from atmospheric neutrinos in next generation proton-decay searches using megaton-scale Water Cherenkov detectors. Similar techniques might also be useful in the detection of supernova neutrinos. Accurate determination of neutron tagging efficiencies will require a detailed understanding of the number of neutrons produced by neutrino interactions in water as a function of momentum transferred. We propose the Atmospheric Neutrino Neutron Interaction Experiment (ANNIE), designed to measure the neutron yield of atmospheric neutrino interactions in gadolinium-doped water. An innovative aspect of the ANNIE design is the use of precision timing to localize interaction vertices in the small fiducial volume of the detector. We propose to achieve this by using early production of LAPPDs (Large Area Picosecond Photodetectors). This experiment will be a first application of these devices demonstrating their feasibility for Water Cherenkov neutrino detectors
Decreased mass specific respiration under experimental warming is robust to the microbial biomass method employed
Hartley et al. question whether reduction in Rmass, under experimental warming, arises because of the biomass method. We show the method they treat as independent yields the same result. We describe why the substrate-depletion hypothesis may not solely explain observed responses, and urge caution in interpretation of the seasonal data. © 2009 Blackwell Publishing Ltd/CNRS
Letters and records of the dissenting congregations: David Crosley, Cripplegate and Baptist Church life
The original publication is available at www.springerlink.comInternational audienceThis chapter examines the status and function of letters in manuscript records of dissenting Churches of the post-Toleration years, concentrating on the correspondence of the Baptist Church of Cripplegate. The letters are placed in the context of controversies about Church government and discipline and the rhetoric used during the scandal caused by the excommunication of its Northern minister David Crosley for drinking, lying and adultery is assessed. In doing so, the chapter pays particular attention to the epistolary exchanges between metropolitan and provincial congregations and to what they reveal about conceptions of the Baptist ministry
HIGH-VELOCITY BIPOLAR MOLECULAR EMISSION from AN AGN TORUS
We have detected in ALMA observations CO J = 6 - 5 emission from the nucleus
of the Seyfert galaxy NGC 1068. The low-velocity (up to +/- 70 km/s relative to
systemic) CO emission resolves into a 12x7 pc structure, roughly aligned with
the nuclear radio source. Higher-velocity emission (up to +/- 400 km/s) is
consistent with a bipolar outflow in a direction nearly perpendicular (roughly
80 degrees) to the nuclear disk. The position-velocity diagram shows that in
addition to the outflow, the velocity field may also contain rotation about the
disk axis. These observations provide compelling evidence in support of the
disk-wind scenario for the AGN obscuring torus.FONDECYT (Grant ID: 3140436), Science and Technology Facilities CouncilThis is the author accepted manuscript. The final version is available from Institute of Physics Publishing via http://dx.doi.org/10.3847/2041-8205/829/1/L
Counter-rotation and High-velocity Outflow in the Parsec-scale Molecular Torus of NGC 1068
We present 1.4 pc resolution observations of 256 GHz nuclear radio continuum
and HCN () in the molecular torus of NGC 1068. The integrated radio
continuum emission has a flat spectrum consistent with free-free emission and
resolves into an X-shaped structure resembling an edge-brightened bicone. HCN
is detected in absorption against the continuum, and the absorption spectrum
shows a pronounced blue wing that suggests a high-velocity molecular outflow
with speeds reaching 450 km/s. Analysis of the off-nucleus emission line
kinematics and morphology reveals two nested, rotating disk components. The
inner disk, inside pc, has kinematics consistent with the nearly
edge-on, geometrically thin water megamaser disk in Keplerian rotation around a
central mass of 1.66\times 10^7\,\mbox{M}_\odot. The outer disk, which
extends to ~pc radius, counter-rotates relative to the inner disk. The
rotation curve of the outer disk is consistent with rotation around the same
central mass as the megamaser disk but in the opposite sense. The morphology of
the molecular gas is asymmetric around the nuclear continuum source. We
speculate that the outer disk formed from more recently introduced molecular
gas falling out of the host galaxy or from a captured dwarf satellite galaxy.
In NGC 1068, we find direct evidence that the molecular torus consists of
counter-rotating and misaligned disks on parsec scales.ERC grant 695671 'QUENCH
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