A Framework for Designing MIMO systems with Decision Feedback Equalization or Tomlinson-Harashima Precoding

We consider joint transceiver design for general Multiple-Input Multiple-Output communication systems that implement interference (pre-)subtraction, such as those based on Decision Feedback Equalization (DFE) or Tomlinson-Harashima precoding (THP). We develop a unified framework for joint transceiver design by considering design criteria that are expressed as functions of the Mean Square Error (MSE) of the individual data streams. By deriving two inequalities that involve the logarithms of the individual MSEs, we obtain optimal designs for two classes of communication objectives, namely those that are Schur-convex and Schur-concave functions of these logarithms. For Schur-convex objectives, the optimal design results in data streams with equal MSEs. This design simultaneously minimizes the total MSE and maximizes the mutual information for the DFE-based model. For Schur-concave objectives, the optimal DFE design results in linear equalization and the optimal THP design results in linear precoding. The proposed framework embraces a wide range of design objectives and can be regarded as a counterpart of the existing framework of linear transceiver design.Comment: To appear in ICASSP 200

Effect of Thermal Loads on Substructures: New Trammel Creek Bridge on KY-100 in Allen County, Kentucky

When infrastructure is subjected to temperature changes, structural members that are either partially or fully restrained against motion can develop internal stresses. The phenomenon of temperature-induced internal stress development in superstructure members has prompted the American Association of State Highway and Transportation Officials (AASHTO) to include provisions for determining superstructure temperature load effects. However, little consideration has been given to explicitly quantifying the effect that thermal stresses have on foundation systems such as intermediate bridge piers. The objective of this study is to instrument a multi-span integral abutment bridge with temperature and bridge response monitoring devices, and ultimately, to make a comparative analysis between measurements of temperature-induced soil pressures with pressures derived using the AASHTO design provisions. Accordingly, the New Trammel Creek Bridge (002B00054N) along KY-100 in Allen County, Kentucky has been fitted with temperature and response instrumentation. Data has being continuously collected from the bridge site since May 2011, and can be viewed at: http://www.ktc.uky.edu/kytc/RemoteBridgeMonitoringInKY/ky100Allen.html. Included in the research is a detailed analytical study of the New Trammel Creek Bridge, performed simultaneously with a field-monitoring program. Finite element (FE) modeling and analysis of temperature loadings on the bridge have pointed to AASHTO superstructure temperature provisions as the preferred method. Also called Method B, the AASHTO provisions led to adequate sizing of bridge foundation members

Nonlinear Dynamic Analysis of Long-Span Cable-Stayed Bridges with Train-Bridge and Cable Coupling

Span lengths of newly constructed cable-stayed railway bridges continue to show increases relative to those of older bridges. Accompanying such increases is the importance of ensuring that vibrations of long-span cable-stayed bridges satisfy both safety and serviceability requirements, particularly for bridges that support train passages. In contrast to modern design of bridges that support roadway vehicles, current methods for analyzing cable-stayed railway bridges do not yet typically account for coupling effects that may occur between cables and the surrounding bridge structure during train passages. This paper presents a computational framework for the nonlinear dynamic analysis of railway bridges based on a coupled train–bridge analytical model and investigates the significance of accounting for cable-related coupling effects. A case study is then carried out, where coupled dynamic responses of cables, towers, and girders of an in-service railway bridge are computed and compared to those obtained using an uncoupled approach. These comparisons demonstrate the merits of accounting for coupling phenomena when computing dynamic characteristics of cable-stayed railway bridges and highlight benefits of the coupled analysis approach in bridge design applications

The XMM Cluster Survey: The Dynamical State of XMMXCS J2215.9-1738 at z=1.457

We present new spectroscopic observations of the most distant X-ray selected galaxy cluster currently known, XMMXCS J2215.9-1738 at z=1.457, obtained with the DEIMOS instrument at the W. M. Keck Observatory, and the FORS2 instrument on the ESO Very Large Telescope. Within the cluster virial radius, as estimated from the cluster X-ray properties, we increase the number of known spectroscopic cluster members to 17 objects, and calculate the line of sight velocity dispersion of the cluster to be 580+/-140 km/s. We find mild evidence that the velocity distribution of galaxies within the virial radius deviates from a single Gaussian. We show that the properties of J2215.9-1738 are inconsistent with self-similar evolution of local X-ray scaling relations, finding that the cluster is underluminous given its X-ray temperature, and that the intracluster medium contains ~2-3 times the kinetic energy per unit mass of the cluster galaxies. These results can perhaps be explained if the cluster is observed in the aftermath of an off-axis merger. Alternatively, heating of the intracluster medium through supernovae and/or Active Galactic Nuclei activity, as is required to explain the observed slope of the local X-ray luminosity-temperature relation, may be responsible.Comment: 13 pages, 6 figures, accepted for publication in Ap

Nevanlinna-Pick interpolation on distinguished varieties in the bidisk

This article treats Nevanlinna-Pick interpolation in the setting of a special class of algebraic curves called distinguished varieties. An interpolation theorem, along with additional operator theoretic results, is given using a family of reproducing kernels naturally associated to the variety. The examples of the Neil parabola and doubly connected domains are discussed.Comment: 31 pages. The question left open at the end of version 1 has been answered in the affirmative; see Theorem 1.12 and Corollary 1.13 in version

Exogenous pulmonary surfactant for the treatment of adult patients with acute respiratory distress syndrome: results of a meta-analysis

INTRODUCTION: The purpose of this study was to perform a systematic review and meta-analysis of exogenous surfactant administration to assess whether this therapy may be useful in adult patients with acute respiratory distress syndrome. METHODS: We performed a computerized literature search from 1966 to December 2005 to identify randomized clinical trials. The primary outcome measure was mortality 28–30 days after randomization. Secondary outcome measures included a change in oxygenation (PaO(2):FiO(2 )ratio), the number of ventilation-free days, and the mean duration of ventilation. Meta-analysis was performed using the inverse variance method. RESULTS: Two hundred and fifty-one articles were identified. Five studies met our inclusion criteria. Treatment with pulmonary surfactant was not associated with reduced mortality compared with the control group (odds ratio 0.97; 95% confidence interval (CI) 0.73, 1.30). Subgroup analysis revealed no difference between surfactant containing surface protein or not – the pooled odds ratio for mortality was 0.87 (95% CI 0.48, 1.58) for trials using surface protein and the odds ratio was 1.08 (95% CI 0.72, 1.64) for trials without surface protein. The mean difference in change in the PaO(2):FiO(2 )ratio was not significant (P = 0.11). There was a trend for improved oxygenation in the surfactant group (pooled mean change 13.18 mmHg, standard error 8.23 mmHg; 95% CI -2.95, 29.32). The number of ventilation-free days and the mean duration of ventilation could not undergo pooled analysis due to a lack of sufficient data. CONCLUSION: Exogenous surfactant may improve oxygenation but has not been shown to improve mortality. Currently, exogenous surfactant cannot be considered an effective adjunctive therapy in acute respiratory distress syndrome

Identification of SUMO Targets Associated with the Pluripotent State in Human Stem Cells

To investigate the role of SUMO modification in the maintenance of pluripotent stem cells, we used ML792, a potent and selective inhibitor of SUMO Activating Enzyme. Treatment of human induced pluripotent stem cells with ML792 resulted in the loss of key pluripotency markers. To identify putative effector proteins and establish sites of SUMO modification, cells were engineered to stably express either SUMO1 or SUMO2 with C-terminal TGG to KGG mutations that facilitate GlyGly-K peptide immunoprecipitation and identification. A total of 976 SUMO sites were identified in 427 proteins. STRING enrichment created three networks of proteins with functions in regulation of gene expression, ribosome biogenesis, and RNA splicing, although the latter two categories represented only 5% of the total GGK peptide intensity. The rest have roles in transcription and the regulation of chromatin structure. Many of the most heavily SUMOylated proteins form a network of zinc-finger transcription factors centered on TRIM28 and associated with silencing of retroviral elements. At the level of whole proteins, there was only limited evidence for SUMO paralogue-specific modification, although at the site level there appears to be a preference for SUMO2 modification over SUMO1 in acidic domains. We show that SUMO influences the pluripotent state in hiPSCs and identify many chromatin-associated proteins as bona fide SUMO substrates in human induced pluripotent stem cells.</p

The XMM Cluster Survey: a massive galaxy cluster at z = 1.45

We report the discovery of XMMXCS J2215.9-1738, a massive galaxy cluster at z=1.45, which was found in the XMM Cluster Survey. The cluster candidate was initially identified as an extended X-ray source in archival XMM data. Optical spectroscopy shows that six galaxies within a ~60" diameter region lie at z=1.45+/-0.01. Model fits to the X-ray spectra of the extended emission yield kT=7.4+2.7-1.8 keV (90% confidence); if there is an undetected central X-ray point source, then kT=6.5+2.6-1.8 keV. The bolometric X-ray luminosity is LX=4.4+0.8-0.6C 1044 ergs s-1 over a 2 Mpc radial region. The measured TX, which is the highest for any known cluster at z&gt;1, suggests that this cluster is relatively massive for such a high redshift. The redshift of XMMXCS J2215.9-1738 is the highest currently known for a spectroscopically confirmed cluster of galaxies

Uniqueness in the Freedericksz transition with weak anchoring

In this paper we consider a boundary value problem for a quasilinear pendulum equation with nonlinear boundary conditions that arises in a classical liquid crystals setup, the Freedericksz transition, which is the simplest opto-electronic switch, the result of competition between reorienting effects of an applied electric field and the anchoring to the bounding surfaces. A change of variables transforms the problem into the equation x = −f(x) for ∈ (−T, T), with boundary conditions x = ± T f(x) at = ∓T, for a convex nonlinearity f. By analyzing an associated inviscid Burgers' equation, we prove uniqueness of monotone solutions in the original nonlinear boundary value problem. This result has been for many years conjectured in the liquid crystals literature, e. g. in E. G. Virga, Variational Theories for Liquid Crystals,Chapman and Hall, London, 1994 and in I. W. Stewart, The Static and Dynamic Continuum Theory of Liquid Crystals: A Mathematical Introduction, Taylor and Francis, London, 2003