Yes, Father

A Catholic Priest, my father, walks the beach in Tampa, 1968. The sun halfway through setting. Facing the water, hands in the pockets of his plaid shorts, he thinks he hears, impossibly blowing in off the empty rippling expanse, a woman singing: “A woman’s voice. It is not the voice of God, at least not the voice that I have been taught to listen for. Her song is the very essence of what we have been schooled in defining as temptation: sensual, sugary, mournful. A woman walking the waves of the sea; I wonder where she is—she who believes in me when I have no right to expect devotion of any sort, when she is the very one I abandoned. If it’s what you need to do, she said. Let’s see how it goes. And then I left. Came to this humid hell by choice and demand, headed south by travel and trope, all for an ideal that from this vantage no longer looks idyllic. She is in New York, where it is just beginning to turn hot, and the park trees are thick and full of shade, unlike the scanty palms that line this beach; their shade barely spans the expanse of my soaked brow. It seems, now that I have left, now that I am here alone—a true priest would not say alone. A true priest would say with God, but I don’t feel like I am with God. I feel alone. Lonely.https://digitalcommons.butler.edu/onearth/1005/thumbnail.jp

Towards validation of a new computerised test of goal neglect: preliminary evidence from clinical and neuroimaging pilot studies

Objective: Goal neglect is a significant problem following brain injury, and is a target for rehabilitation. It is not yet known how neural activation might change to reflect rehabilitation gains. We developed a computerised multiple elements test (CMET), suitable for use in neuroimaging paradigms. Design: Pilot correlational study and event-related fMRI study. Methods: In Study 1, 18 adults with acquired brain injury were assessed using the CMET, other tests of goal neglect (Hotel Test; Modified Six Elements Test) and tests of reasoning. In Study 2, 12 healthy adults underwent fMRI, during which the CMET was administered under two conditions: self-generated switching and experimenter-prompted switching. Results: Among the clinical sample, CMET performance was positively correlated with both the Hotel Test (r = 0.675, p = 0.003) and the Modified Six Elements Test (r = 0.568, p = 0.014), but not with other clinical or demographic measures. In the healthy sample, fMRI demonstrated significant activation in rostro-lateral prefrontal cortex in the self-generated condition compared with the prompted condition (peak 40, 44, 4; ZE = 4.25, p(FWEcorr) = 0.026). Conclusions: These pilot studies provide preliminary evidence towards the validation of the CMET as a measure of goal neglect. Future studies will aim to further establish its psychometric properties, and determine optimum pre- and post-rehabilitation fMRI paradigms

The research buyer\u27s perspective of market research effectiveness

This study examines the views of research buyers about the efficacy of market research used within their firms. A sample of research buyers from Australia's top 1000 companies was asked to evaluate the research outcomes of their most recent market research project in terms of their overall business strategy. Specialist market research buyers (insights managers) believed their commissioned research was very effective. This was in contrast to research buyers in generalist roles who did not believe in the effectiveness of the research outcomes to the same extent. The overarchlng strategic direction adopted by the buyer's firm did not make a difference to the type of research conducted (,action orientated' vs. 'knowledge enhancing'). However, entrepreneurial firms were more likely to rate their research as effective and to have dedicated research buyers generating insights into their markets. The results of this study are inconsistent with earlier studies and indicate that the market research function within Australian firms stili plays an ambiguous role

MARKET STRUCTURE AND INNOVATION INTENSITY IN AGRICULTURAL BIOTECH

Consolidations and spin-offs in the agricultural biotechnology industry and the growing links of multinational corporations with the food and feed industry have been the subject of considerable discussion among academics, policy makers, consumers, and farmers. Most of the research by academic and overnment institutions has focused on the reasons for consolidation. Little theoretical or empirical research has examined the impact of this consolidation. We adapt an endogenous growth model of industry structure and R&D to agricultural biotechnology and empirically estimate the model. These empirical estimates, the main focus of the paper, indicate that industry consolidation influences the amount and direction of research, which then feeds back to influence industry structure.Agribusiness, Marketing, Research and Development/Tech Change/Emerging Technologies,

Mixing the reactive with the personal: Opportunities for end-user programming in personal information management

The transition of personal information management (PIM) tools off the desktop to the Web presents an opportunity to augment these tools with capabilities provided by the wealth of real-time information readily available. In this chapter, we describe a personal information assistance engine that lets end-users delegate to it various simple context- and activity-reactive tasks and reminders. Our system, Atomate, treats RSS/ATOM feeds from social networking and life-tracking sites as sensor streams, integrating information from such feeds into a simple unified RDF world model representing people, places and things and their time-varying states and activities. Combined with other information sources on the web, including the user's online calendar, web-based e-mail client, news feeds and messaging services, Atomate can be made to automatically carry out a variety of simple tasks for the user, ranging from context-aware filtering and messaging, to sharing and social coordination actions. Atomate's open architecture and world model easily accommodate new information sources and actions via the addition of feeds and web services. To make routine use of the system easy for non-programmers, Atomate provides a constrained-input natural language interface (CNLI) for behavior specification, and a direct-manipulation interface for inspecting and updating its world model

The sensory acceptance of fibre-enriched cereal foods:a meta-analysis

Improved understanding of the sensory responses to fibre fortification may assist manufacturers and health promotion efforts. The effects of fibre fortification (or modified ingredients) on sensory acceptability of baked cereal foods (bread, cookies, muffins) were estimated by linear random-effects meta-analysis of twenty eligible studies (869 panellists, 34% male). As little as 2 g per 100 g fortification caused moderate–large reductions in overall acceptability, flavour acceptability, and appearance acceptability in most items, with cookies most negatively affected. Fortification of base nonfortified foods with low initial acceptability improved acceptability; however, at higher basic levels, fortification lowered acceptability. Fortification improved texture acceptability of muffins and bread with low base acceptability, but lowered texture acceptability when base acceptability was high. Flavour improvement of muffins with fortification decreased with increasing base food acceptability. Fibre fortification of baked cereal foods lowers acceptability, but food format and base food acceptability affect the magnitude and direction of responses. Refining fibre fortification approaches could improve consumer uptake

Rescaling the Governance of Renewable Energy : Lessons from the UK Devolution Experience

An earlier version of this paper was presented at the symposium ‘Scale in environmental governance: power reconfiguration, democratic legitimacy and institutional (mis-)fit’, Berlin-Brandenburg Academy of Sciences and Humanities, Berlin 7-8 March 2013. We would like to thank the symposium participants, special issue editors and three anonymous referees for their comments and advice.Peer reviewe

Perfluorocarbon Enhanced Glasgow Oxygen Level Dependent (GOLD) magnetic resonance metabolic imaging identifies the penumbra following acute ischemic stroke

The ability to identify metabolically active and potentially salvageable ischaemic penumbra is crucial for improving treatment decisions in acute stroke patients. Our solution involves two complementary novel MRI techniques (Glasgow Oxygen Level Dependant (GOLD) Metabolic Imaging), which when combined with a perfluorocarbon (PFC) based oxygen carrier and hyperoxia can identify penumbra due to dynamic changes related to continued metabolism within this tissue compartment. Our aims were (i) to investigate whether PFC offers similar enhancement of the second technique (Lactate Change) as previously demonstrated for the T2*OC technique (ii) to demonstrate both GOLD metabolic imaging techniques working concurrently to identify penumbra, following administration of Oxycyte® (O-PFC) with hyperoxia. Methods: An established rat stroke model was utilised. Part-1: Following either saline or PFC, magnetic resonance spectroscopy was applied to investigate the effect of hyperoxia on lactate change in presumed penumbra. Part-2; rats received O-PFC prior to T2*OC (technique 1) and MR spectroscopic imaging, which was used to identify regions of tissue lactate change (technique 2) in response to hyperoxia. In order to validate the techniques, imaging was followed by [14C]2-deoxyglucose autoradiography to correlate tissue metabolic status to areas identified as penumbra. Results: Part-1: PFC+hyperoxia resulted in an enhanced reduction of lactate in the penumbra when compared to saline+hyperoxia. Part-2: Regions of brain tissue identified as potential penumbra by both GOLD metabolic imaging techniques utilising O-PFC, demonstrated maintained glucose metabolism as compared to adjacent core tissue. Conclusion: For the first time in vivo, enhancement of both GOLD metabolic imaging techniques has been demonstrated following intravenous O-PFC+hyperoxia to identify ischaemic penumbra. We have also presented preliminary evidence of the potential therapeutic benefit offered by O-PFC. These unique theranostic applications would enable treatment based on metabolic status of the brain tissue, independent of time from stroke onset, leading to increased uptake and safer use of currently available treatment options

Commencement Address: Winter Quarter, 2002

Commencement address given by David L. Brennan, Chair of the OSU Board of Trustees, to the Winter 2002 graduating class of The Ohio State University, St. John Arena, Columbus, Ohio, March 15, 2002