942 research outputs found
Antitrust Enfocement and High-Technology Markets
Although the antitrust laws apply to all industries, the application must be tempered in each case by the myriad ways in which competition can be modified by structural, behavioral, technological, regulatory, and other characteristics. The Commission applies the antitrust laws with sensitivity to the special characteristics of high-tech industries and of intellectual property, but also with the recognition that--as in other industries--competition plays an important role in spurring innovation and in spreading the benefits of that innovation to consumers. This focus is not new. This balanced approach has roots that go back at least to the 1977 Antitrust Guide to International Operations in the Ford Administration and the 1988 Antitrust Guidelines for International Operations in the last year of the Reagan Administration, and is set forth in the 1995 Antitrust Guidelines for the Licensing of Intellectual Property four years ago. It is also informed by the extensive hearings and detailed reporting by the Commission three years ago on antitrust in the 21st century. Of course, enforcement in this area is not entirely free from controversy. A few critics question whether the antitrust laws that were originally designed to apply to traditional manufacturing and distribution industries should be applied at all to competition in fast-moving industries where products often are quickly outmoded and market share may be ephemeral. Others express concern about the potential conflict between the antitrust laws and the laws that protect intellectual property. Are monopolies granted under U. S. patent laws fundamentally in conflict with the antimonopoly focus of the Sherman Act and later antitrust statutes? Can intellectual property rights coexist with effective antitrust enforcement
A Comparison of the Use of Binary Decision Trees and Neural Networks in Top Quark Detection
The use of neural networks for signal vs.~background discrimination in
high-energy physics experiment has been investigated and has compared favorably
with the efficiency of traditional kinematic cuts. Recent work in top quark
identification produced a neural network that, for a given top quark mass,
yielded a higher signal to background ratio in Monte Carlo simulation than a
corresponding set of conventional cuts. In this article we discuss another
pattern-recognition algorithm, the binary decision tree. We have applied a
binary decision tree to top quark identification at the Tevatron and found it
to be comparable in performance to the neural network. Furthermore,
reservations about the "black box" nature of neural network discriminators do
not apply to binary decision trees; a binary decision tree may be reduced to a
set of kinematic cuts subject to conventional error analysis.Comment: 14pp. Plain TeX + mtexsis.tex (latter available through 'get
mtexsis.tex'.) Two postscript files avail. by emai
Heart of Darkness: The Significance of the Zeptobarn Scale for Neutralino Direct Detection
The direct detection of dark matter through its elastic scattering off
nucleons is among the most promising methods for establishing the particle
identity of dark matter. The current bound on the spin-independent scattering
cross section is sigma^SI < 10 zb for dark matter masses m_chi ~ 100 GeV, with
improved sensitivities expected soon. We examine the implications of this
progress for neutralino dark matter. We work in a supersymmetric framework
well-suited to dark matter studies that is simple and transparent, with models
defined in terms of four weak-scale parameters. We first show that robust
constraints on electric dipole moments motivate large sfermion masses mtilde >
1 TeV, effectively decoupling squarks and sleptons from neutralino dark matter
phenomenology. In this case, we find characteristic cross sections in the
narrow range 1 zb 70 GeV. As sfermion masses are
lowered to near their experimental limit mtilde ~ 400 GeV, the upper and lower
limits of this range are extended, but only by factors of around two, and the
lower limit is not significantly altered by relaxing many particle physics
assumptions, varying the strange quark content of the nucleon, including the
effects of galactic small-scale structure, or assuming other components of dark
matter. Experiments are therefore rapidly entering the heart of dark
matter-favored supersymmetry parameter space. If no signal is seen,
supersymmetric models must contain some level of fine-tuning, and we identify
and analyze several possibilities. Barring large cancellations, however, in a
large and generic class of models, if thermal relic neutralinos are a
significant component of dark matter, experiments will discover them as they
probe down to the zeptobarn scale.Comment: 35 pages, 11 figures; v2: references added, figures extended to 2 TeV
neutralino masses, XENON100 results included, published versio
ESTIMATING THE SUBJECT BY TREATMENT INTERACTION IN NON-REPLICATED CROSSOVER DIET STUDIES
Researchers in human nutrition commonly refer to the ‘consistent’ diet effect (i.e. the main effect of diet) and an ‘inconsistent’ diet effect (i.e. a subject by diet interaction). However, due to the non-replicated designs of most studies, one can only estimate the first part using ANOVA; the latter (interaction) is confounded with the residual noise. In many diet studies, it appears that subjects do respond differently to the same diet, so the subject by diet interaction may be large. In a search of over 40,000 published human nutrition studies, most using a crossover design, we found that in none was a subject by diet interaction effect estimated. For this paper, we examined LDL-cholesterol data from a non-replicated crossover study with four diets, the typical American diet, with and without added plant sterols, and a cholesterol-lowering Step-1 diet, with and without sterols. We also examined LDL-cholesterol data from a second crossover study with some replications with three diets, representing the daily supplement of 0, 1 or 2 servings of pistachio nuts. These two data sets were chosen because experience suggested that LDLcholesterol responses to diet tend to be subject-specific. The second data set, with some replication, allowed us to estimate the subject by diet interaction term in a traditional ANOVA framework. One approach to estimating an interaction effect in non-replicated studies is through the use of a multiplicative decomposition of the interaction (sometimes called AMMI―additive main effects, multiplicative interaction). In this type of analysis, residuals, formed after estimated main effects are subtracted from the data, are arrayed in a matrix with diets as columns and subjects as rows. A singular value decomposition of the matrix is performed and the first, or first and second, principal component(s) are used as estimates of the interaction, and can be tested for significance using approximate F-tests. Using the R gnm package, we found large and significant subject by diet interaction effects in both data sets; estimates of the interaction in the second data set were similar to interaction estimates from traditional ANOVA. Of an additional 26 dependent variables from the first and a third data set (the latter investigating the effect of mild alcohol consumption on blood variables), 19 had significant subject by diet interactions, based on the AMMI methodology. These results suggest that the subject by diet interaction is often important and should not be ignored when analyzing data obtained from non-replicated crossover designs―the AMMI methodology works well and is readily available in statistical software packages
Plant Community Response to Regional Sources of Dominant Grasses in Grasslands Restored Across a Longitudinal Gradient
Restorations in the light of climate change will need to take into account whether or not sources of the dominant plants are adapted to the future conditions at a site. In addition, the effect of these dominants, especially if sourced from outside the local area, on the assembling plant community needs assessment. We investigated how different ecotypes of the tallgrass prairie dominants Andropogon gerardii and Sorghastrum nutans affect assembling prairie communities. Four reciprocal common garden experiments were established across a longitudinal climate gradient characterized by a decrease in aridity in western Kansas (COLBY), central Kansas (HAYS), eastern Kansas (MANHATTAN), and southern Illinois (CARBONDALE). At each site, plots were seeded with ecotypes of A. gerardii and S. nutans sourced from central Kansas (CKS), eastern Kansas (EKS), southern Illinois (SIL), or a mix of all three regional ecotypes (MIX). All plots were also seeded with the same suite of seven subordinate species. Species composition was measured during the fourth year of restoration. The greatest variation between communities occurred at HAYS and CARBONDALE between plots seeded with CKS and SIL ecotypes. At these sites, plots seeded with the local source had the lowest diversity and cover of nondominant species. Compositional variation between plots seeded with different dominant grass ecotypes was found exclusively at CARBONDALE between CKS and SIL plots. Differences between locally seeded plots and plots seeded with a MIX of dominant grass ecotypes were contingent upon site. At CARBONDALE, MIX seeded plots had higher diversity than SIL ecotype plots. Our results indicate that across a wide geographic precipitation gradient, limited but important differences in community assembly occur in restorations established with different ecotypes of the dominant grasses. However, our results also support the use of mixtures of nonlocal ecotypes of dominant grasses in restorations without risk to the assembling plant community. Future studies need to determine the potential for out- breeding effects among seed sources in mixed stands
Invariant mass distributions in cascade decays
We derive analytical expressions for the shape of the invariant mass
distributions of massless Standard Model endproducts in cascade decays
involving massive New Physics (NP) particles, D -> Cc -> Bbc -> Aabc, where the
final NP particle A in the cascade is unobserved and where two of the particles
a, b, c may be indistinguishable. Knowledge of these expressions can improve
the determination of NP parameters at the LHC. The shape formulas are
composite, but contain nothing more complicated than logarithms of simple
expressions. We study the effects of cuts, final state radiation and detector
effects on the distributions through Monte Carlo simulations, using a
supersymmetric model as an example. We also consider how one can deal with the
width of NP particles and with combinatorics from the misidentification of
final state particles. The possible mismeasurements of NP masses through `feet'
in the distributions are discussed. Finally, we demonstrate how the effects of
different spin configurations can be included in the distributions.Comment: 39 pages, 14 figures (colour), JHEP clas
Acceptance of Simulated Oral Rabies Vaccine Baits by Urban Raccoons
In summer 1986, a study was conducted to evaluate raccoon (Procyon lotor) acceptance of oral baits that could be used for rabies vaccination, One thousand wax-coated sponge bait cubes were filled with 5 mg of a seromarker (iophenoxic acid), placed in polyethylene bags, and hand-distributed in an 80 ha area within an urban National Park in Washington, D.C. (USA), After 3 wk, target and nontarget animals were trapped and blood samples collected to evaluate bait uptake. Thirty-three of 52 (63%) raccoons had elevated blood iodine levels indicating they had eaten at least one bait, 13 (25%) were negative, and six (12%) had marginal values, These results indicate that sponge baits hand-placed at a density of 12,4/ha can reach a significant proportion of an urban raccoon population. Implications for oral rabies vaccination of raccoons are discussed
General Neutralino NLSPs at the Early LHC
Gauge mediated supersymmetry breaking (GMSB) is a theoretically
well-motivated framework with rich and varied collider phenomenology. In this
paper, we study the Tevatron limits and LHC discovery potential for a wide
class of GMSB scenarios in which the next-to-lightest superpartner (NLSP) is a
promptly-decaying neutralino. These scenarios give rise to signatures involving
hard photons, 's, 's, jets and/or higgses, plus missing energy. In order
to characterize these signatures, we define a small number of minimal spectra,
in the context of General Gauge Mediation, which are parameterized by the mass
of the NLSP and the gluino. Using these minimal spectra, we determine the most
promising discovery channels for general neutralino NLSPs. We find that the
2010 dataset can already cover new ground with strong production for all NLSP
types. With the upcoming 2011-2012 dataset, we find that the LHC will also have
sensitivity to direct electroweak production of neutralino NLSPs.Comment: 26 page
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