SOCIAL RESPONSIBILITY: BETWEEN THE PROPOSED AND THE THINKABLE

ABSTRACT This article deserves to discuss in both the legal and the corporate world the practices adopted by Brazilian companies that seek to disseminate a more democratic working environment, especially respect for differences and prevention policies directed at HIV-positive workers, with a view to Independence of legal predictions consonant with the jurisprudential understandings materialized in the social dynamics. Methodologically, we sought to interpret extensively the constitutional principles, especially the neoconstitutional current and other devices inherent in the Federal Constitution. It was concluded that there are still shortcomings, mainly, regarding the supervision of work environments, demonstrating, therefore, that the constitutional text is emptied when it should be considered as an instrument of preservation and social construction KEYWORDS: Labor Law; Constitutional Guarantees; Neo-constitutionalism. RESUMO O presente artigo se digna a debater tanto no universo jurídico quanto empresarial, as práticas adotadas pelas empresas brasileiras que procuram disseminar um ambiente de trabalho mais democrático, em especial o respeito às diferenças e as políticas de prevenção direcionada aos trabalhadores portadores de HIV, objetivando a independência de previsões legais consonantes aos entendimentos jurisprudenciais materializados na dinâmica social. Metodologicamente, buscou-se interpretar de forma extensiva dos princípios constitucionais, em especial pela corrente neoconstitucional e dos demais dispositivos inerentes na Constituição Federal. Concluiu-se que ainda há insuficiências, principalmente, no tocante à fiscalização dos ambientes de trabalho, demonstrando, portanto, que o texto constitucional se vê esvaziado quando deveria ser tido como instrumento de preservação e construção social   PALAVRAS-CHAVE: Direito do Trabalho; Garantias Constitucionais; Neoconstitucionalismo.

Functional Characterization of Bacteria Isolated from Ancient Arctic Soil Exposes Diverse Resistance Mechanisms to Modern Antibiotics

Using functional metagenomics to study the resistomes of bacterial communities isolated from different layers of the Canadian high Arctic permafrost, we show that microbial communities harbored diverse resistance mechanisms at least 5,000 years ago. Among bacteria sampled from the ancient layers of a permafrost core, we isolated eight genes conferring clinical levels of resistance against aminoglycoside, $\beta$-lactam and tetracycline antibiotics that are naturally produced by microorganisms. Among these resistance genes, four also conferred resistance against amikacin, a modern semi-synthetic antibiotic that does not naturally occur in microorganisms. In bacteria sampled from the overlaying active layer, we isolated ten different genes conferring resistance to all six antibiotics tested in this study, including aminoglycoside, $\beta$-lactam and tetracycline variants that are naturally produced by microorganisms as well as semi-synthetic variants produced in the laboratory. On average, we found that resistance genes found in permafrost bacteria conferred lower levels of resistance against clinically relevant antibiotics than resistance genes sampled from the active layer. Our results demonstrate that antibiotic resistance genes were functionally diverse prior to the anthropogenic use of antibiotics, contributing to the evolution of natural reservoirs of resistance genes.Organismic and Evolutionary Biolog

A LITERATURA INFANTIL NEGRA EM SALA DE AULA

Objetivamos descrever uma experiência de formação docente sobre a prática com a Literatura Infantil Negra (LIN), destacando a relevância de momentos formativos com a temática. Além disso, buscamos investigar as possibilidades de práticas com a LIN para a sala de aula a partir da referida experiência. A pesquisa, de cunho qualitativo, contou com as contribuições de Gomes (2002, 2005), Candido (2004, 2006), Amarilha (2001) e Campos (2016) para a construção do nosso arcabouço teórico. Foi realizado o minicurso Literatura Infantil Negra na Escola (LINE) em um município do Rio Grande do Norte. As professoras que participaram do minicurso desenvolveram planejamentos que evidenciaram as contribuições do LINE para as possíveis práticas, bem como as lacunas que precisam ser preenchidas com novos momentos formativos. Compreendemos que são necessárias reflexões que nos levem a promover uma formação qualidade para os professores da educação básica sobre LIN

Evaluation of adherence to pharmacological treatment

The adherence to therapy associated with the socio-demographic variables and the habits of patients with hypertension and/or diabetes mellitus were investigated in this study. The registration forms of 105 patients in the Hiperdia program in the municipality of Campina Grande-PB were used as a data collection instrument, applying the Morisky-Green test (MGT) and Batalla test (BT) to assess compliance treatment. For the MGT, there was a prevalence of non-adherent individuals (76.2%) and the type of predominant behavior was unintentional. The internal consistency of the responses obtained through the MGT presented good reliability, according to the value of 0.69 obtained by Cronbach’s alpha. For the BT, there was a predominance of adherence (68.6%) and the alpha value was 0.80, showing a high reliability level. It was found that a diet lacking in salt is a strong impact variable for determining the adherence to the BT. Given the representativity of the tests, there is a need to amend the interferences that facilitate the low adherence to drug treatment. The results of this study can be used to construct strategies that will address these difficulties and optimize the adherence level and quality of life of patients

E. coli catheter-associated urinary tract infections are associated with distinctive virulence and biofilm gene determinants

Urinary catheterization facilitates urinary tract colonization by E. coli and increases infection risk. Here, we aimed to identify strain-specific characteristics associated with the transition from colonization to infection in catheterized patients. In a single-site study population, we compared E. coli isolates from patients with catheter-associated asymptomatic bacteriuria (CAASB) to those with catheter-associated urinary tract infection (CAUTI). CAUTI isolates were dominated by a phylotype B2 subclade containing the multidrug-resistant ST131 lineage relative to CAASB isolates, which were phylogenetically more diverse. A distinctive combination of virulence-associated genes was present in the CAUTI-associated B2 subclade. Catheter-associated biofilm formation was widespread among isolates and did not distinguish CAUTI from CAASB strains. Preincubation with CAASB strains could inhibit catheter colonization by multiple ST131 CAUTI isolates. Comparative genomic analysis identified a group of variable genes associated with high catheter biofilm formation present in both CAUTI and CAASB strains. Among these, ferric citrate transport (Fec) system genes were experimentally associated with enhanced catheter biofilm formation using reporter and fecA deletion strains. These results are consistent with a variable role for catheter biofilm formation in promoting CAUTI by ST131-like strains or resisting CAUTI by lower-risk strains that engage in niche exclusion

O uso da tecnologia de digitalização tridimensional na preservação de bens materiais instalados em espaços públicos

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Me tomo cinco minutos... me tomo una HSI!

HSI es la sigla inglesa de imagen hiperespectral. En este resumen se presentan los resultados parciales obtenidos como parte del plan de trabajos de una beca externa de Conicet realizada en el Instituto de Química (UNICAMP). El objeto de este trabajo ha sido desarrollar y estudiar los alcances de una metodología alternativa, basada en la espectrometría molecular en la región del infrarrojo cercano (NIR) combinada con métodos quimiométricos, para la clasificación de muestras de té (Camellia sinensis) de acuerdo a su origen geográfico. Para ello, se tomaron imágenes hiperespectrales en la zona del NIR de muestras comerciales de té negro y té verde provenientes de distintos países del Mercosur (Argentina, Paraguay y Brasil). Una HSI es una imagen digital que contiene un espectro molecular por cada pixel, permitiendo revelar y visualizar la distribución espacial de numerosos compuestos químicos. Como consecuencia de esta arquitectura, cada HSI acarrea una gran cantidad de datos dispuestos en forma de tres dimensiones, 2 (dos) referidas a la distribución de pixeles y la tercera con los valores correspondientes a cada espectro, lo que hace necesario emplear técnicas de análisis multivariante de imágenes para obtener información relevante de las mismas. Resultados y ConclusionesEn este trabajo se presentan los resultados obtenidos para 15 muestras de té verde. Las muestras fueron comprimidas a pastillas previo a su análisis. Se tomaron HSI de 3 puntos diferentes en cada muestra utilizando un sistema de obtención de imágenes hiperespectrales (Perkin-Elmer Spotlight 400N) en la región espectral de 4000 a 7800 cm-1 generando una HSI (16×16×254) en cada punto. Una vez importados los archivos, los hipercubos de cada imagen se descompusieron en matrices aumentadas por columna (unfolding) que fueron analizadas mediante el método MCR-ALS (1-2). El método MCR-ALS permite obtener los perfiles de concentración y espectros de los componentes puros presentes en cada muestra. Cinco (5) componentes resultaron óptimos para hacer converger el algoritmo, con una falta de ajuste inferior al 1,0%. Los resultados de los perfiles de abundancia de cada componente se utilizaron luego para la aplicación de diferentes métodos de clasificación multivariante, LDA, PLS-DA y SVM-DA. Los resultados obtenidos demostraron que el método SVM-DA fue el que tuvo mejor desempeño y fue capaz de modelar la matriz de datos con una taza de acierto superior al 90% cuando se utilizó el método de validación cruzada por lotes (10-fold cross validation).Fil: Hidalgo, Melisa Jazmin. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Química Básica y Aplicada del Nordeste Argentino. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas Naturales y Agrimensura. Instituto de Química Básica y Aplicada del Nordeste Argentino; ArgentinaFil: Dantas, William. Universidade Estadual Do Campinas. Instituto de Química.; BrasilFil: Pellerano, Roberto Gerardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Nordeste. Instituto de Química Básica y Aplicada del Nordeste Argentino. Universidad Nacional del Nordeste. Facultad de Ciencias Exactas Naturales y Agrimensura. Instituto de Química Básica y Aplicada del Nordeste Argentino; ArgentinaFil: Poppi, Ronei Jesus. Universidade Estadual Do Campinas. Instituto de Química.; Brasil9º Congreso Argentino de Química analíticaRío CuartoArgentinaAsociación Argentina de Química Analític

An annotated avian inventory of the Brazilian state of Alagoas, one of the world’s most threatened avifauna

The northeast Brazilian state of Alagoas harbors a rather diverse, and one of the world’s most threatened, avifauna. However, the knowledge about its avifauna is currently scattered on several publications and the state’s birds have never been comprehensively assembled into a checklist. To fill this shortfall, we present here the first critical review of all available bird records for the state of Alagoas. We present a list of 520 bird species recorded in the state, of which 503 are supported by documentary evidence. We also comment on the distribution, migratory movements, taxonomy and conservation of the region’s avifauna and correct previous misidentified or invalid records for the state