24 research outputs found

    Hawking-Moss Tunneling with a Dirac-Born-Infeld Action

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    The Hawking-Moss tunneling rate for a field described by the Dirac-Born-Infeld action is calculated using a stochastic approach. We find that the effect of the non-trivial kinetic term is to enhance the tunneling rate, which can be exponentially significant. This result should be compared to the DBI enhancement found in the Coleman-de Luccia case.Comment: 4 pages, version accepted in Phys. Rev. D., additional references and example applicatio

    A Brachistochrone Approach to Reconstruct the Inflaton Potential

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    We propose a new way to implement an inflationary prior to a cosmological dataset that incorporates the inflationary observables at arbitrary order. This approach employs an exponential form for the Hubble parameter H(Ï•)H(\phi) without taking the slow-roll approximation. At lowest non-trivial order, this H(Ï•)H(\phi) has the unique property that it is the solution to the brachistochrone problem for inflation.Comment: 13 pages, 2 figures, version matches published versio

    Efficient ancestry and mutation simulation with msprime 1.0

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    Stochastic simulation is a key tool in population genetics, since the models involved are often analytically intractable and simulation is usually the only way of obtaining ground-truth data to evaluate inferences. Because of this, a large number of specialized simulation programs have been developed, each filling a particular niche, but with largely overlapping functionality and a substantial duplication of effort. Here, we introduce msprime version 1.0, which efficiently implements ancestry and mutation simulations based on the succinct tree sequence data structure and the tskit library. We summarize msprime’s many features, and show that its performance is excellent, often many times faster and more memory efficient than specialized alternatives. These high-performance features have been thoroughly tested and validated, and built using a collaborative, open source development model, which reduces duplication of effort and promotes software quality via community engagement

    Expanding the stdpopsim species catalog, and lessons learned for realistic genome simulations

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    Simulation is a key tool in population genetics for both methods development and empirical research, but producing simulations that recapitulate the main features of genomic datasets remains a major obstacle. Today, more realistic simulations are possible thanks to large increases in the quantity and quality of available genetic data, and the sophistication of inference and simulation software. However, implementing these simulations still requires substantial time and specialized knowledge. These challenges are especially pronounced for simulating genomes for species that are not well-studied, since it is not always clear what information is required to produce simulations with a level of realism sufficient to confidently answer a given question. The community-developed framework stdpopsim seeks to lower this barrier by facilitating the simulation of complex population genetic models using up-to-date information. The initial version of stdpopsim focused on establishing this framework using six well-characterized model species (Adrion et al., 2020). Here, we report on major improvements made in the new release of stdpopsim (version 0.2), which includes a significant expansion of the species catalog and substantial additions to simulation capabilities. Features added to improve the realism of the simulated genomes include non-crossover recombination and provision of species-specific genomic annotations. Through community-driven efforts, we expanded the number of species in the catalog more than threefold and broadened coverage across the tree of life. During the process of expanding the catalog, we have identified common sticking points and developed the best practices for setting up genome-scale simulations. We describe the input data required for generating a realistic simulation, suggest good practices for obtaining the relevant information from the literature, and discuss common pitfalls and major considerations. These improvements to stdpopsim aim to further promote the use of realistic whole-genome population genetic simulations, especially in non-model organisms, making them available, transparent, and accessible to everyone

    U can: physics I for dummies

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    COLEMAN-DE LUCCIA TUNNELING AND THE GIBBONS-HAWKING TEMPERATURE

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    We study Coleman-de Luccia tunneling in some detail. We show that, for a single scalar field potential with a true and a false vacuum, there are four types of tunneling, depending on the properties of the potential. A general tunneling process involves a combination of thermal (Gibbons-Hawking temperature) fluctuation part way up the barrier followed by quantum tunneling. The thin-wall approximation is a special limit of the case (of only quantum tunneling) where inside the nucleation bubble is the true vacuum while the outside reaches the false vacuum. Hawking-Moss tunneling is the (only thermal fluctuation) limit of the case where the inside of the bubble does not reach the true vacuum at the moment of its creation, and the outside is cut off by the de Sitter horizon before it reaches the false vacuum. A typical tunneling process is a combination of thermal and quantum tunnelings. We estimate the tunneling rate for this case and find that the corrections to the Hawking-Moss formula can be large. In all cases, we see that the Euclidean action of the bounce decreases rapidly as the vacuum energy density increases, signaling that the tunneling is not exponentially suppressed. This phenomenon may be interpreted as a finite temperature effect due to the Gibbons Hawking temperature of the de Sitter space. As an application, we discuss the implication of this tunneling property to the cosmic landscape

    Efficient ancestry and mutation simulation with msprime 1.0

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    Stochastic simulation is a key tool in population genetics, since the models involved are often analytically intractable and simulation is usually the only way of obtaining ground-truth data to evaluate inferences. Because of this, a large number of specialized simulation programs have been developed, each filling a particular niche, but with largely overlapping functionality and a substantial duplication of effort. Here, we introduce msprime version 1.0, which efficiently implements ancestry and mutation simulations based on the succinct tree sequence data structure and the tskit library. We summarize msprime’s many features, and show that its performance is excellent, often many times faster and more memory efficient than specialized alternatives. These high-performance features have been thoroughly tested and validated, and built using a collaborative, open source development model, which reduces duplication of effort and promotes software quality via community engagement
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