2, 4-Dimethyl-6-hydroxyacetophenone oxime and 3, 5-dibromo-2, 4-dimethyl-6- hydroxyacetophenone oxime as reagents and diethylamine as a synergist in the extraction and separation of metals

1022-10242,4-Dimethyl-6-hydroxyacetophenone oxime and 3,5- dibromo-2,4-dimethyl-6-hydroxyacetophenone oxime act as very good reagents for the extraction and separation of Cu(II), Ni(II), Co(II), Fe(III) and Mn(II). Addition of diethylamine as a synergist in the extraction system, not only increases the per cent extraction of the metals but also the molar absorbances of the complexes. The separation of the metals from one another, viz., Cu(II) from Ni(II), Cu(II) from Co(II) and Cu(II) and Ni(II) from Cr(III) becomes far more easier in the presence of diethylamine

HLA-DR and -DQ antibodies in the sera of South India Parous women

HLA-A, -B positive sera of south Indian parous women were screened for the presence of HLA-DR and -DQ antibodies. The sera were absorbed with pooled platelets in a micro-method and screened against HLA-DR and -DQ typed B-lymphocytes panel. Out of fifty two sera, twenty were found to contain HLA-DR and -DQ antibodies. Seven sera were demonstrated to be specific for well defined DR and DQ antigen

Spectrophotometric determination of trace amounts of cadmium with iodide and methyl violet

445-446A selective spectrophotometric method based on the interaction of an anionic iodo complex of cadmium with methyl violet has been described for the determination of trace amounts of cadmium. The developed method is precise, accurate and has been applied to determination of cadmium at trace levels (25 ppb) in sea water and high purity samples of indium and zinc materials

Review of harm-benefit analysis in the use of animals in research

This is the final version of the report. Available from the Home Office via the link in this recordReport of our review of the processes of harm-benefit analysis (HBA) carried out under the UK Animals (Scientific Procedures) Act 1986 (A(SP)A).Report of the Animals in Science Committee Harm-Benefit Analysis Sub-Group chaired by Professor Gail Davies. The Animals in Science Committee Harm-Benefit Analysis subgroup, chaired by Professor Gail Davies, has produced a review of the harm-benefit analysis (HBA). This review is an analysis of the underpinnings and implementation of the HBA which remains a crucial step in the justification of the use of animals in science. It is published in response to a ministerial commission.Animals in Science Committe

Agro-materials : a bibliographic review

Facing the problems of plastic recycling and fossil resources exhaustion, the use of biomass to conceive new materials appears like a reasonable solution. Two axes of research are nowadays developed : on the one hand the synthesis of biodegradable plastics, whichever the methods may be, on the other hand the utilization of raw biopolymers, which is the object of this paper. From this perspective, the “plastic” properties of natural polymers, the caracteristics of the different classes of polymers, the use of charge in vegetable matrix and the possible means of improving the durability of these agro-materials are reviewed

Calculation of the Phase Behavior of Lipids

The self-assembly of monoacyl lipids in solution is studied employing a model in which the lipid's hydrocarbon tail is described within the Rotational Isomeric State framework and is attached to a simple hydrophilic head. Mean-field theory is employed, and the necessary partition function of a single lipid is obtained via a partial enumeration over a large sample of molecular conformations. The influence of the lipid architecture on the transition between the lamellar and inverted-hexagonal phases is calculated, and qualitative agreement with experiment is found.Comment: to appear in Phys.Rev.

VIPERdb2: an enhanced and web API enabled relational database for structural virology

VIPERdb (http://viperdb.scripps.edu) is a relational database and a web portal for icosahedral virus capsid structures. Our aim is to provide a comprehensive resource specific to the needs of the virology community, with an emphasis on the description and comparison of derived data from structural and computational analyses of the virus capsids. In the current release, VIPERdb2, we implemented a useful and novel method to represent capsid protein residues in the icosahedral asymmetric unit (IAU) using azimuthal polar orthographic projections, otherwise known as Φ–Ψ (Phi–Psi) diagrams. In conjunction with a new Application Programming Interface (API), these diagrams can be used as a dynamic interface to the database to map residues (categorized as surface, interface and core residues) and identify family wide conserved residues including hotspots at the interfaces. Additionally, we enhanced the interactivity with the database by interfacing with web-based tools. In particular, the applications Jmol and STRAP were implemented to visualize and interact with the virus molecular structures and provide sequence–structure alignment capabilities. Together with extended curation practices that maintain data uniformity, a relational database implementation based on a schema for macromolecular structures and the APIs provided will greatly enhance the ability to do structural bioinformatics analysis of virus capsids