1,477 research outputs found

    Spectrally efficient transmit diversity scheme for differentially modulated multicarrier transmissions

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    Cyclic delay diversity is a simple, yet effective, transmit diversity scheme for multicarrier based transmissions employing coherent digital linear modulation schemes. It is shown that, for satisfactory operation, the scheme requires additional channel estimation overhead compared to single antenna and traditional space–time coded transmissions owing to the inherent increase in frequency selective fading. The authors analyse the additional channel estimation overhead requirement for a Hiperlan #2 style system with two transmit antennas operating in a NLOS indoor environment. The analysis shows that an additional overhead of 500% is required for the candidate system compared to a single antenna system. It is also shown that by employing differential modulation the channel estimation overhead can be eliminated with significant performance improvement compared to a system employing a practical channel estimation scheme. This novel combination, termed ‘differentially modulated cyclic delay diversity, is shown to yield a highly spectral efficient, yet simple transmit diversity solution for multi-carrier transmissions

    Accurate Judgment by Dementia Patients of Neutral Faces with Respect to Trustworthiness and Valence

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    The present study investigates whether dementia patients can make accurate social and affective judgments of face stimuli. We used verbal material as a control condition to see whether dementia patients are capable of using the rating scales the same way as controls. We compared the trustworthiness, valence, and arousal ratings of dementia patients with those from a healthy control group. Participants rated pictures of young and old, female and male neutral faces and two fictitious biographies. The results indicate that dementia patients make accurate judgments of unfamiliar faces with respect to trustworthiness and valence. Results concerning arousal ratings suggest that the corresponding scale might be difficult to use for dementia patients and possibly for older participants as well

    Opera and the Limits of Philosophy: on Bernard Williams's Music Criticism

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    Development of Ground-testable Phase Fresnel Lenses in Silicon

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    Diffractive/refractive optics, such as Phase Fresnel Lenses (PFL's), offer the potential to achieve excellent imaging performance in the x-ray and gamma-ray photon regimes. In principle, the angular resolution obtained with these devices can be diffraction limited. Furthermore, improvements in signal sensitivity can be achieved as virtually the entire flux incident on a lens can be concentrated onto a small detector area. In order to verify experimentally the imaging performance, we have fabricated PFL's in silicon using gray-scale lithography to produce the required Fresnel profile. These devices are to be evaluated in the recently constructed 600-meter x-ray interferometry testbed at NASA/GSFC. Profile measurements of the Fresnel structures in fabricated PFL's have been performed and have been used to obtain initial characterization of the expected PFL imaging efficiencies.Comment: Presented at GammaWave05: "Focusing Telescopes in Nuclear Astrophysics", Bonifacio, Corsica, September 2005, to be published in Experimental Astronomy, 8 pages, 3 figure

    Model based optimization of transflection near infrared spectroscopy as a process analytical tool in a continuous flash pasteurizer

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    Near infrared spectroscopy in combination with a transflection probe was investigated as inline measurement in a continuous flash pasteurizer system with a sugar–water model solution. Robustness and reproducibility of fluctuations of recorded spectra as well as trueness of the chemometric analysis were compared under different process parameter settings. Variable parameters were the flow rate (from laminar flow at 30 L/h to turbulent flow at 90 L/h), temperature (20 to 100 °C) and the path length of the transflection probe (2 and 4 mm) while the pressure was kept constant at 2.5 bar. Temperature and path length were identified as the most affecting parameters, in case of homogenous test medium. In case of particle containing systems, the flow rate could have an impact as well. However, the application of a PLS model, which includes a broad temperature range, and the correction of prediction results by applying a polynomial regression function for prediction errors, was able to compensate these effects. Also, a path length of 2 mm leads to a higher accuracy. The applied strategy shows that by the identification of relevant process parameters and settings as well as the establishment of a compensation strategy, near infrared spectroscopy is a powerful process analytical tool for continuous flash pasteurization systems.BMBF, 13FH024IX6, IngenieurNachwuchs 2016: Cyber-Physisches System (CPS) zur thermischen Entkeimung von Getränken unter Nutzung der NIR-Sensorik als Schlüsseltechnologi

    FPGA basierte, konfigurierbare OFDM Sender-Plattform für die Positionsbestimmung mittels TDoA

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    Für die Evaluierung von Algorithmen zur Positionsbestimmung nach dem Time Difference of Arrival – Verfahren wird eine frei konfigurierbare OFDM Sender-Plattform benötigt. Da die Berechnung in Echtzeit erfolgen soll, ist eine Implementierung in rekonfigurierbarer Hardware (FPGA) erforderlich. Das Manuskript gibt sowohl einen Überblick über die Hintergründe und die Architektur des Sendesystems, als auch einen tieferen Einblick in verschiedene Lösungsdetails

    Angle resolved photoelectron spectroscopy of two-color XUV-NIR ionization with polarization control

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    Electron emission caused by extreme ultraviolet (XUV) radiation in the presence of a strong near infrared (NIR) field leads to multiphoton interactions that depend on several parameters. Here, a comprehensive study of the influence of the angle between the polarization directions of the NIR and XUV fields on the two-color angle-resolved photoelectron spectra of He and Ne is presented. The resulting photoelectron angular distribution strongly depends on the orientation of the NIR polarization plane with respect to that of the XUV field. The prevailing influence of the intense NIR field over the angular emission characteristics for He(1s) and Ne(2p) ionization lines is shown. The underlying processes are modeled in the frame of the strong field approximation (SFA) which shows very consistent agreement with the experiment reaffirming the power of the SFA for multicolor-multiphoton ionization in this regime

    Dental and Maxillofacial Cone Beam CT-High Number of Incidental Findings and Their Impact on Follow-Up and Therapy Management.

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    Cone beam computed tomography (CBCT) is increasingly used for dental and maxillofacial imaging. The occurrence of incidental findings has been reported, but clinical implications of these findings remain unclear. The study's aim was to identify the frequency and clinical impact of incidental findings in CBCT. A total of 374 consecutive CBCT examinations of a 3 year period were retrospectively evaluated for the presence, kind, and clinical relevance of incidental findings. In a subgroup of 54 patients, therapeutic consequences of CBCT incidental findings were queried from the referring physicians. A total of 974 incidental findings were detected, involving 78.6% of all CBCT, hence 2.6 incidental findings per CBCT. Of these, 38.6% were classified to require treatment, with an additional 25.2% requiring follow-up. Incidental findings included dental pathologies in 55.3%, pathologies of the paranasal sinuses and airways in 29.2%, osseous pathologies in 14.9% of all CBCT, and findings in the soft tissue or TMJ in few cases. Clinically relevant dental incidental findings were detected significantly more frequently in CBCT for implant planning compared to other indications (60.7% vs. 43.2%, p < 0.01), and in CBCT with an FOV ≥ 100 mm compared to an FOV < 100 mm (54.7% vs. 40.0%, p < 0.01). Similar results were obtained for paranasal incidental findings. In a subgroup analysis, 29 of 54 patients showed incidental findings which were previously unknown, and the findings changed therapeutical management in 19 patients (35%). The results of our study highlighted the importance of a meticulous analysis of the entire FOV of CBCT for incidental findings, which showed clinical relevance in more than one in three patients. Due to a high number of clinically relevant incidental findings especially in CBCT for implant planning, an FOV of 100 × 100 mm covering both the mandible and the maxilla was concluded to be recommendable for this indication

    Neuroinflammation and structural injury of the fetal ovine brain following intra-amniotic Candida albicans exposure.

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    BackgroundIntra-amniotic Candida albicans (C. Albicans) infection is associated with preterm birth and high morbidity and mortality rates. Survivors are prone to adverse neurodevelopmental outcomes. The mechanisms leading to these adverse neonatal brain outcomes remain largely unknown. To better understand the mechanisms underlying C. albicans-induced fetal brain injury, we studied immunological responses and structural changes of the fetal brain in a well-established translational ovine model of intra-amniotic C. albicans infection. In addition, we tested whether these potential adverse outcomes of the fetal brain were improved in utero by antifungal treatment with fluconazole.MethodsPregnant ewes received an intra-amniotic injection of 10(7) colony-forming units C. albicans or saline (controls) at 3 or 5 days before preterm delivery at 0.8 of gestation (term ~ 150 days). Fetal intra-amniotic/intra-peritoneal injections of fluconazole or saline (controls) were administered 2 days after C. albicans exposure. Post mortem analyses for fungal burden, peripheral immune activation, neuroinflammation, and white matter/neuronal injury were performed to determine the effects of intra-amniotic C. albicans and fluconazole treatment.ResultsIntra-amniotic exposure to C. albicans caused a severe systemic inflammatory response, illustrated by a robust increase of plasma interleukin-6 concentrations. Cerebrospinal fluid cultures were positive for C. albicans in the majority of the 3-day C. albicans-exposed animals whereas no positive cultures were present in the 5-day C. albicans-exposed and fluconazole-treated animals. Although C. albicans was not detected in the brain parenchyma, a neuroinflammatory response in the hippocampus and white matter was seen which was characterized by increased microglial and astrocyte activation. These neuroinflammatory changes were accompanied by structural white matter injury. Intra-amniotic fluconazole reduced fetal mortality but did not attenuate neuroinflammation and white matter injury.ConclusionsIntra-amniotic C. albicans exposure provoked acute systemic and neuroinflammatory responses with concomitant white matter injury. Fluconazole treatment prevented systemic inflammation without attenuating cerebral inflammation and injury

    The Dynamic Exponent of the Two-Dimensional Ising Model and Monte Carlo Computation of the Sub-Dominant Eigenvalue of the Stochastic Matrix

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    We introduce a novel variance-reducing Monte Carlo algorithm for accurate determination of autocorrelation times. We apply this method to two-dimensional Ising systems with sizes up to 15×1515 \times 15, using single-spin flip dynamics, random site selection and transition probabilities according to the heat-bath method. From a finite-size scaling analysis of these autocorrelation times, the dynamical critical exponent zz is determined as z=2.1665z=2.1665 (12)
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