16 research outputs found
Concept mapping as a tool to break disciplinary boundaries: isomerism in biological systems
- Publication venue
- Programa de Pós-Graduação em Educação para a Ciência, Bauru: Faculdade de Ciências, UNESP
- Publication date
- 01/01/2008
- Field of study
O mapeamento conceitual foi utilizado como uma ferramenta para verificar as mudanças conceituais de estudantes de Ensino Médio após a realização de atividades didáticas desenvolvidas durante as aulas de Química. O objetivo pedagógico a ser atingido foi romper as fronteiras que segregam o conhecimento científico em disciplinas isoladas. Os estudantes foram intencionalmente provocados a relacionar conceitos de Química e de Biologia, a fim de compreender melhor e explicar as conseqüências biológicas da isomeria. Os mapas conceituais elaborados pelos estudantes, antes e após as atividades propostas, evidenciaram o aparecimento de relações entre conceitos químicos e biológicos, que foram avaliadas qualitativamente. Este trabalho mostra que os mapas conceituais podem ser utilizados como ferramentas para auxiliar o professor na realização de práticas didáticas interdisciplinares na escola, bem como para acompanhar o progresso dos estudantes em direção à interdisciplinaridade.Concept mapping was used as a tool for checking the conceptual changes caused by didactic activities implemented during chemistry classes in high school. Its pedagogical aim was to break down the boundaries, which segregate scientific knowledge into isolated disciplines. The students were intentionally provoked to merge concepts from chemistry and biology, in order to better understand and explain the biological consequences of isomerism. The concept maps produced by the students before and after the activities confirmed the appearance of relationships among chemical and biological concepts, which were qualitatively evaluated. This work shows that concept maps can be used to follow the students' progress towards interdisciplinarity, and to help the teacher to devise future classroom activities to reinforce and to expand interdisciplinary relationships.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) - PIBI
Mapeamneto conceitual como estratégia para romper fronteiras disciplinares: a isomeria nos sistemas biológicos
- Publication venue
- Publication date
- 01/01/2008
- Field of study
Concept mapping was used as a tool for checking the conceptual changes caused by didactic activities implemented during chemistry classes in high school. Its pedagogical aim was to break down the boundaries, which segregate scientific knowledge into isolated disciplines. The students were intentionally provoked to merge concepts from chemistry and biology, in order to better understand and explain the biological consequences of isomerism. The concept maps produced by the students before and after the activities confirmed the appearance of relationships among chemical and biological concepts, which were qualitatively evaluated. This work shows that concept maps can be used to follow the students' progress towards interdisciplinarity, and to help the teacher to devise future classroom activities to reinforce and to expand interdisciplinary relationships.O mapeamento conceitual foi utilizado como uma ferramenta para verificar as mudanças conceituais de estudantes de Ensino Médio após a realização de atividades didáticas desenvolvidas durante as aulas de Química. O objetivo pedagógico a ser atingido foi romper as fronteiras que segregam o conhecimento científico em disciplinas isoladas. Os estudantes foram intencionalmente provocados a relacionar conceitos de Química e de Biologia, a fim de compreender melhor e explicar as conseqüências biológicas da isomeria. Os mapas conceituais elaborados pelos estudantes, antes e após as atividades propostas, evidenciaram o aparecimento de relações entre conceitos químicos e biológicos, que foram avaliadas qualitativamente. Este trabalho mostra que os mapas conceituais podem ser utilizados como ferramentas para auxiliar o professor na realização de práticas didáticas interdisciplinares na escola, bem como para acompanhar o progresso dos estudantes em direção à interdisciplinaridade
Development and validation of a telephone classification interview for common chronic headache disorders
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The interplay between auxin and the cell cycle during plant development
- Author
- A Cruz-Ramírez
- A Goverse
- A Niebel
- A Peres
- A Pettkó-Szandtner
- AK Weimer
- AS Hemerly
- B Berckmans
- B Rybel De
- C Chevalier
- C Galinha
- C Manzano
- C Richard
- CB Orchard
- CL Walcher
- D Dudits
- D Inzé
- DA Sorrell
- E Benková
- E Liscum
- F Roudier
- F Tardieu
- G Gheysen
- GB Monshausen
- GB Monshausen
- GE Noorden van
- H Fukaki
- H Fukaki
- H Fukaki
- H Ren
- HC Vodermaier
- HW Lee
- I Landrieu
- I Smet De
- I Smet De
- I Smet De
- J Almeida Engler de
- J Almeida Engler de
- J Heyman
- J Hof Van’t
- J Leene Van
- JAH Murray
- JC Pozo del
- JC Pozo del
- JC Pozo del
- JC Wilmoth
- JE Malamy
- JG Dubrovsky
- JG Dubrovsky
- JG Torrey
- JJ King
- JL Celenza Jr
- JM Norman Van
- K Himanen
- K Himanen
- K Schutter De
- K Sugimoto
- K Takanashi
- K Vandepoele
- K Xu
- K Zhang
- K Zhang
- L Jansen
- L Jansen
- L Sanz
- L Veylder De
- L Veylder De
- LM Blakely
- M Aida
- M Bel Van
- M Delarue
- M Fan
- M Ito
- M Menges
- M Shishova
- M Umeda
- M-C Chupeau
- MA Moreno-Risueno
- MC Martinez
- MJ Laskowski
- ML Churchman
- MV Bradley
- MW Bayliss
- P Doerner
- P Ferreira
- P Valente
- P Vieira
- PA Sabelli
- PCG Ferreira
- PCL John
- PCL John
- PG Lloret
- R Atta
- R Soni
- R Sozzani
- RJ DiDonato
- S Burssens
- S Dhondt
- S Jurado
- S Vanneste
- SP Gordon
- T Beeckman
- T Cools
- T Goh
- T Hewezi
- T Ishida
- T Murashige
- T Ulmasov
- T Ulmasov
- T Ulmasov
- TJ Donner
- VA Grieneisen
- W Boerjan
- W Grunewald
- W Grunewald
- W Tao
- Y Okushima
- Y Okushima
- Y Sun
- Z Feng
- Z Magyar
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
The essential role of auxin for cell proliferation in plants is well known. Both auxin signaling and cell cycle regulation have been studied elaborately, but less is known about the connection between these processes. Recent studies report on the first molecular pathways that have been found to directly link auxin levels to the regulation of cell cycle activity. Here, we discuss the general effect of auxin on cell cycle progression and then zoom in on the interplay between auxin and the cell cycle during root development in Arabidopsis thaliana. At the root tip, an auxin gradient maintains the correct organization of the ground tissue layers and controls the size of the root apical meristem. During auxin-induced lateral root initiation LATERAL ORGAN BOUNDARIES-DOMAIN transcription factors are upregulated and control reactivation of the cell cycle and cell specification, both of which are needed for proper lateral root initiation. Auxin-induced lateral root initiation-like pathways are also involved in cell cycle reactivation during the formation of nematode feeding sites, nitrogen-fixing nodules and callus tissue, pointing to the existence of one common auxin–cell cycle module to initiate new organs in plants
B
- Author
- A Arneodo
- A Arneodo
- A Baernstein
- A Beĭlins
- A Beĭlinson
- A Beĭlinson
- A Bhattacharyya
- A Brøndsted
- A Brøndsted
- A Delandsheer
- A Dvoretzky
- A Dvoretzky
- A Dvoretzky
- A Einstein
- A Liulevicius
- A Micali
- A Micali
- A Pajor
- A Pelczynski
- A Prothero
- A Rényi
- A Rényi
- A Schinzel
- A Springall
- A Springall
- A Szankowskl
- A Szymanski
- A Thayse
- A Thayse
- A Thayse
- A Thayse
- A Weil
- A Wiles
- AA Bukhstab
- AA Giannopoulos
- AA Giannopoulos
- AD Talantsev
- AD Talantsev
- AH Land
- AH Land
- AIN Veku
- AJ Berrick
- AJ Berrick
- AJ Berrick
- ALT Paterson
- AM Samarov
- AN Griskhov
- AN Iusem
- AN Iusem
- AN Kolmogorov
- AN Kolmogorov
- AP Calderón
- AR Pierro de
- AR Pierro de
- AV Bitsadze
- AV Kuz’Minykh
- B Banaschewski
- B Banaschewski
- B Beauzamy
- B Beauzamy
- B Buchberger
- B Buchberger
- B Davis
- B Farrahi
- B Fine
- B Finetti De
- B Huppert
- B Huppert
- B Jonsson
- B Jonsson
- B Jónsson
- B Jónsson
- B Jónsson
- B Jónsson
- B Jónsson
- B Jónsson
- B Jørgensen
- B Jørgensen
- B Külshammer
- B Külshammer
- B Mazur
- B Simon
- BA Fuks
- BM Lake
- BP Adhikari
- BS Kashin
- BY Chen
- C Boor De
- C Boor De
- C Fefferman
- C Fefferman
- C Ferrari
- C Hipp
- C Hooley
- C Mallol
- C Vidal
- C Vidal
- C Vinti
- CA Micchelli
- CE Bonferroni
- CH Papadimitriou
- CH Papadimitriou
- Ch Pommerenke
- CJ Moreno
- CP May
- CP May
- CR Rao
- CR Rao
- CS Hoo
- CS Hoo
- CS Hoo
- CS Hoo
- CS Hoo
- CS Hoo
- D Arnold
- D Bochmann
- D Bochmann
- D Bochmann
- D Bochmann
- D Cohen
- D Cox
- D Eisenbud
- D Janssens
- D Laugwitz
- D Mangeron
- D Mangeron
- D McHale
- D Mundici
- D Niebur
- D Nualart
- D Nualart
- D Ornstein
- D Quillen
- D Reimer
- D Revuz
- D Stroock
- DB Ray
- DC Ravenel
- DC Ravenel
- DL Burkholder
- DL Burkholder
- DL Burkholder
- DL Colton
- DR Brill
- DR Lewis
- E Asplund
- E Betti
- E Bisho
- E Bishop
- E Bombieri
- E Bombieri
- E Bombieri
- E Calabi
- E Catalan
- E DeGiorgi
- E Fouvry
- E Hairer
- E Hairer
- E Hellinger
- E Lanckau
- E Landvogt
- E Lukács
- E Lutwak
- E Stein
- E Witten
- ED Gluskin
- ED Gluskin
- ED Gluskin
- ED Gluskin
- EH Brown
- EM Schröder
- EM Schröder
- EM Stein
- ET Bell
- F Altomare
- F Argoul
- F Argoul
- F Benford
- F Brafman
- F Brafman
- F Bruhat
- F Buekenhout
- F John
- F John
- F Liese
- F Radó
- F Rlchman
- F Tricerri
- FB Knight
- FFD Bruno
- FG Gustavson
- FJ Almgren Jr
- FP Greenleaf
- FS Beckman
- G Birkhoff
- G Buskes
- G Chaudhuri
- G Chaudhuri
- G Chaudhuri
- G Chaudhuri
- G Dahlquist
- G David
- G Farin
- G Farin
- G Grimmett
- G Pisier
- G Pisier
- G Pisier
- G Schechtman
- G Warner
- G Warner
- G Weiss
- GAF Seber
- GAF Seber
- GD Birkhoff
- GE Bredon
- GE Bredon
- GEP Box
- GEP Box
- GF Steinke
- GG Lipscomb
- GG Lorentz
- GG Lorentz
- GH Hardy
- GL Nemhauser
- GL Nemhauser
- H Berens
- H Blumberg
- H Bohman
- H Chernoff
- H Davenport
- H Dym
- H Dym
- H Endo
- H Endo
- H Endo
- H Endo
- H Endo
- H Halberstam
- H Halberstam
- H Halberstam
- H Halberstam
- H Halberstam
- H Hironaka
- H Iwaniec
- H Lebesgue
- H Maier
- H Mori
- H Nagao
- H Nagao
- H Rund
- H Schaeffer
- H Sugita
- H Sugita
- H Triebel
- H Wallman
- H-J Samaga
- HA Barnes
- HC Yuen
- HC Yuen
- HE White Jr
- HH Gonska
- HL Krall
- HL Montgomery
- HW Gould
- HW Gould
- I Babuška
- I Babuška
- I Ekeland
- I Ekeland
- I Gel’fand
- I Gohberg
- I Gohberg
- I Gohberg
- I Gohberg
- I Kra
- I Pitowsky
- I Roșca
- IF Pinelis
- IJ Good
- IJ Good
- IJ Schoenberg
- IJ Schoenberg
- IM Gessel
- IM Isaacs
- IM Isaacs
- IM Singer
- IMH Etherington
- IV Basawa
- J Apel
- J Berg Van Den
- J Bliedtner
- J Bourgain
- J Bourgain
- J Bourgain
- J Bourgain
- J Bourgain
- J Diestel
- J Diestel
- J Encarnaçao
- J Encarnaçao
- J Friedlander
- J Galambos
- J Galambos
- J Galambos
- J Galambos
- J Galambos
- J Galambos
- J Galambos
- J Galambos
- J Galambos
- J Galambos
- J Galambos
- J García-Cuervas
- J Garnett
- J Hinz
- J Hinz
- J Hoschek
- J Hoschek
- J Hurrelbrink
- J Lehner
- J Lehner
- J Lester
- J Lindenstrauss
- J Lindenstrauss
- J Lindenstrauss
- J Lipman
- J Moser
- J Moser
- J Pawlikowski
- J Riordan
- J Schneid
- J Schreier
- J Simons
- J Stoer
- J Thévenaz
- J Thévenaz
- J Tits
- J-P Kahane
- J-P Serre
- J-P Serre
- JA Sanders
- JA Yan
- JB Brown
- JB Brown
- JB Brown
- JC Becker
- JC Bradford
- JC Breckenridge
- JC Butcher
- JC Butcher
- JC Gutiérrez
- JC Meer van der
- JCC Mckinsey
- JCC Mckinsey
- JD Borwanker
- JE Broadwell
- JE Grizzle
- JE Grizzle
- JF Clauser
- JF Clauser
- JG Oldroyd
- JM Anderson
- JM Fontaine
- JM Fontaine
- JM Fontaine
- JM Rassias
- JM Rassias
- JM Rassias
- JM Rassias
- JM Rassias
- JM Rassias
- JMF Castillo
- JP Serre
- JR Partington
- JS Bell
- JS Bell
- JW Pitman
- JW Pitman
- JW Pitman
- JWP Hirschfeld
- K Burrage
- K Dekker
- K Donner
- K Iséki
- K Iséki
- K Iséki
- K Iséki
- K Iséki
- K Iséki
- K Itô
- K Jordan
- K Matusita
- K Matusita
- K Nomizu
- K Prachar
- K Varadarajan
- K Yano
- K Yano
- K Yano
- K Yano
- K Yano
- K Yano
- KA Baker
- KL Chun
- KM Rangaswamy
- L Blcan
- L Blcan
- L Cam Le
- L Cesari
- L Cesari
- L Comtet
- L Comtet
- L Comtet
- L Fuchs
- L Fuchs
- L Fuchs
- L Henkin
- L Henkin
- L Puig
- L Puig
- L Puig
- L Puig
- L Puig
- L Puig
- L Rubel
- L Russo
- L Takács
- L Takács
- L Takács
- LA Shepp
- LG Lewis
- LG Lewis
- LJ Gleser
- LM Bregman
- LM Bregman
- LR Ford Jr
- LR Ford Jr
- LV Kantorovich
- M Abramowitz
- M Becker
- M Bercovier
- M Brelot
- M Broué
- M Broué
- M Crouzeix
- M Dugas
- M Dugas
- M Golubitsky
- M Golubitsky
- M Gromov
- M Hazewinkel
- M Heilmann
- M Heilmann
- M Heilmann
- M Heilmann
- M Kolster
- M Kolster
- M Matsumoto
- M Rudelson
- M Sitaramayya
- M Valdivia
- M Wilhelm
- MCR Butler
- ME Mortensen
- ME Mortensen
- MJ Ablowitz
- MJ Ablowitz
- MJ Ablowitz
- MK Singh
- MM Day
- MM Derriennic
- MT Alcalde
- MV Berry
- MW Kracht
- N Aronszajn
- N Bohr
- N Bouleau
- N Bouleau
- N Ercolani
- N Ikeda
- N Kazamaki
- N Tanaka
- N Tomczak-Jaegermann
- N Tomczak-Jaegermann
- N Tomczak-Jaegermann
- NA Shanin
- NL Bassily
- NL Johnson
- NT Varopoulos
- O Hatori
- O Moreno
- O Moreno
- O Moreno
- P Billard
- P Brand
- P Brandi
- P Brandi
- P Brandi
- P Brandi
- P Deligne
- P Diaconis
- P Enflo
- P Gaspard
- P Hill
- P Holgate
- P Levy
- P Mankiewicz
- P Mankiewicz
- P Maroni
- P Mccullagh
- P Mccullagh
- P Protter
- P Schatte
- P Tomter
- PD Lax
- PE Conner
- PL Antonelli
- PL Antonelli
- PL Butzer
- PM Cohn
- PN Agrawal
- PP Korovkin
- PR Halmos
- PR Halmos
- PT Bateman
- Q Hu
- R Abraham
- R Bolue
- R Bolue
- R Bolue
- R Bolue
- R Brauer
- R Brauer
- R Brauer
- R Brauer
- R Brauer
- R Brauer
- R Brauer
- R Brauer
- R Brauer
- R Brauer
- R Duduchava
- R Frank
- R Frank
- R Frank
- R Fritsch
- R Gatignol
- R Goldblatt
- R Goldblatt
- R Goldblatt
- R Goldblatt
- R Goldblatt
- R Goldblatt
- R Goldblatt
- R Goldblatt
- R Gordon
- R Léandre
- R Metz
- R Mises von
- R Monaco
- R Nishii
- R Nishii
- R Raimi
- R Riley
- R Scheuring
- R Scheuring
- R Schneider
- R Schneider
- R Timoney
- R Timoney
- RA Bradley
- RA Bradley
- RA Bradley
- RA Bradley
- RA Bradley
- RA Bradley
- RA DeVore
- RA DeVore
- RB Bird
- RB Burckel
- RBLS Prakasa
- RBLS Prakasa
- RBLS Prakasa
- RBLS Prakasa
- RBLS Prakasa
- RBLS Prakasa
- RC Alperin
- RC James
- RF Werner
- RG Swan
- RH Cushman
- RJ Beaver
- RJ Beaver
- RJ Darin
- RJ Darin
- RM Shreshtha
- RM Shreshtha
- RP Gilbert
- RP Sinha
- RP Stanley
- RR Bahadur
- RR Bahadur
- RR Coifman
- RR Coifman
- RR Phelps
- RT Rockafellar
- RT Shield
- RT Shield
- S Banach
- S Banach
- S Banach
- S Bergman
- S Bergman
- S Bloch
- S Bochner
- S Fang
- S González
- S Illman
- S Illman
- S Kakutani
- S Kullback
- S Lichtenbaum
- S Nag
- S Newcomb
- S Ray
- S Roman
- S Tachibana
- S Tachibana
- S Tanno
- S Tanno
- S Todorcevic
- S Wagon
- S Walukiewicz
- S Walukiewicz
- S Watanabe
- S Watanabe
- S Zionts
- S Zionts
- SB Akers
- SB Akers
- SC Port
- SDR Wilson
- SG Krantz
- SG Krantz
- SJ Summers
- SJ Szarek
- SJ Szarek
- SJ Szarek
- SJ Szarek
- SJ Szarek
- SJ Wilson
- SJ Wilson
- SM Ali
- SM Kwerel
- SM Kwerel
- SM Webster
- SN Bernstein
- SN Bernstein
- SN Bernstein
- SN Bernstein
- SN Bernstein
- SP Novikov
- SP Singh
- SS Chern
- SS Chern
- SS Chern
- SS Kim
- T Bröcker
- T Bröcker
- T Fiala
- T Figiel
- T Figiel
- T Figiel
- T Hill
- T Hill
- T Kailath
- T Matumoto
- T Matumoto
- T Nebrunn
- T Nishiura
- T Platkowski
- T Shiga
- TB Benjamin
- TB Benjamin
- TC Papanastasiou
- TE Harris
- U Albrech
- V Bunyakovskli
- V Jha
- V Maier
- V Snaith
- V Snaith
- VA Baskakov
- VA Baskakov
- VD Milman
- VD Milman
- VD Milman
- VD Milman
- VD Milman
- VD Milman
- VE Gurarii
- VFR Jones
- VI Arnol’d
- VM Abraham
- W Auzinger
- W Auzinger
- W Auzinger
- W Benz
- W Benz
- W Benz
- W Boehm
- W Boehm
- W DeBaere
- W Schachermayer
- W Schlenk
- W Sierpiński
- W Stromquist
- W Trinks
- W Vasconcelos
- WH Fleming
- WH Fleming
- WJ Davis
- WM Beynon
- WM Beynon
- WM Boothby
- WS Wilson
- WW Adam
- WY Hsiang
- WY Hsiang
- WY Hsiang
- WY Hsiang
- WY Hsiang
- X Zhou
- X Zhou
- Y Aharonov
- Y Benyamini
- Y Censor
- Y Gordon
- Y Gordon
- Y Imai
- Y Imai
- Y Imai
- Y Katznelson
- Y Meyer
- Y Motohashi
- Y Suzuki
- Y Suzuki
- Y Suzuki
- YA Rozanov
- YI Lyubich
- YV Linnik
- YY Nikitin
- Z Bai
- Z Ditzian
- Z Ditzian
- Z Piotrowski
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1997
- Field of study
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries
- Author
- Aaltonen L.
- Aaltonen V.
- Agee M.
- Akafo Stephen
- Akiyama Masato
- allen N.
- Allingham R.R.
- Amersinghe Nishani
- Arvas M.
- Asai S.
- Ashaye Adeyinka
- Aslam T.
- Aslibekyan S.
- Atan D.
- Auge F.
- Aung Tin
- Auranen A.
- Auro K.
- Auton Adam
- Auvinen P.
- Awaisa G.
- Bailey Jessica N. Cooke
- Barman S.
- Barrett J.
- Bell R.K.
- Betts J.
- Bhangale T.
- Bing N.
- Birney Ewan
- Bishop P.
- Biswas S.
- Black G.
- Blomster T.
- Bonnemaijer Pieter W. M.
- Bowers N.
- Brein G.
- Brilliant M.
- Bronson P.
- Bryc K.
- Budenz D.L.
- Bunce C.
- Burdon K.
- Call K.
- Carare R.
- Carpen O.
- Casson R.J.
- Chakravarthy U.
- Challis B.
- Chan M.
- Chang D.
- Chatelain C.
- Chen C.-Y.
- Chen H.
- Chen H.
- Chen Li Jia
- Chen X.
- Cheng Ching-Yu
- Chhibber A.
- Choquet Helene
- Chu A.
- Cipriani V.
- Clark S.K.
- Close D.
- Cooke Bailey J.N.
- Craig Jamie E.
- Cree Angela J.
- Crohns M.
- Currant Hannah
- Dada A.
- Daida H.
- Davis J.W.
- Day A.
- Della Briotta Parolo P.
- Desai P.
- Dhillon B.
- Dick A.
- Diogo D.
- Doney A.
- Donner K.
- Eaton S.
- Egan C.
- Ehm M.
- Eicher J.
- Eklund K.
- Elenius K.
- Elson S.L.
- Emi M.
- Emoto N.
- Ennis S.
- Esmaeeli S.
- Fingert J.H.
- Fitzgerald J.T.
- Fletez-Brant K.
- Fontanillas P.
- Foster Paul J.
- Foster Paul J.
- Fox C.
- Fruttiger M.
- Fujioka T.
- Furlotte N.A.
- Furukawa Y.
- Färkkilä M.
- Gaasterland D.
- Gaasterland T.
- Gallacher J.
- Gandhi P.M.
- Ganna A.
- Garway-Heath D.
- Georgantas B.
- Gharahkhani Puya
- Ghosh S.
- Gibson J.
- Goldberg I.
- Gordillo J.E.
- Gore D.
- Gormley P.
- Gossel M.
- Graham S.L.
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 24/02/2021
- Field of study
10.1038/s41467-020-20851-4Nature Communications121125
New insights into the genetic etiology of Alzheimer’s disease and related dementias
- Author
- A David Smith
- Aaltonen L.
- Aaltonen V.
- Aarno Palotie
- Aarsland D.
- Aavikko M.
- Abalos M. S.
- Abdelnour C.
- Abner E.
- Abraham R.
- Ad Adarmes-Gómez
- Adam Boxer
- Adam Ziemann
- Adams H.
- Adams P. M.
- Adarmes-Gómez A.
- Adarmes-Gómez A. D.
- Adriana Gamboa
- Adrienne L Cupples
- Adrienne Tin
- Aguilera N.
- Aguilera N.
- Aguirre A.
- Agustina Legaz
- Ahmad S.
- Aimee Pierce
- Aino Salminen
- Airi Jussila
- Aisha Khaleeq
- Aki Havulinna
- Akinyemi R. O.
- Al-Chalabi A.
- Alan B Stevens
- Alan Lerner
- Alarcón-Martín E.
- Albert M. S.
- Alberto Benussi
- Albin R. L.
- Alcolea D.
- Aldo Saenz
- Alegret M.
- Alessandra Chesi
- Alessandro Vacca
- Alexander Teumer
- Alexis Brice
- Ali M.
- Alisa Manning
- Alison E Fohner
- Allan I Levey
- Allen M.
- Allende I. R.
- Alonso M. D.
- Alonso M. D.
- Alvarez I.
- Alvarez L.
- Alvin Thomas
- Alyssa Aguirre
- Amanda Cano
- Amanda Elliott
- Amanda G Smith
- Amanda J Myers
- Amer-Ferrer G.
- Amin N.
- Ammar Al-Chalabi
- Amouyel P.
- Amy Gerrish
- Amy Williams
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- Anders Malarstig
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- Yeunjoo E Song
- Yi Zhao
- Ying Wu
- Yoav Ben-Shlomo
- Yogen Patel
- Younkin S. G.
- Yu C. -E.
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- Yuanchao Zhang
- Yuk Yee Leung
- Yunfeng Huang
- Yunju Yang
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- Zdenka Pausova
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- Zulaica M.
- Zulma Sevillano
- Álvarez V.
- Åsa Hedman
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
Characterization of the genetic landscape of Alzheimer’s disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage genome-wide association study totaling 111,326 clinically diagnosed/‘proxy’ AD cases and 677,663 controls. We found 75 risk loci, of which 42 were new at the time of analysis. Pathway enrichment analyses confirmed the involvement of amyloid/tau pathways and highlighted microglia implication. Gene prioritization in the new loci identified 31 genes that were suggestive of new genetically associated processes, including the tumor necrosis factor alpha pathway through the linear ubiquitin chain assembly complex. We also built a new genetic risk score associated with the risk of future AD/dementia or progression from mild cognitive impairment to AD/dementia. The improvement in prediction led to a 1.6- to 1.9-fold increase in AD risk from the lowest to the highest decile, in addition to effects of age and the APOE ε4 allele
A first update on mapping the human genetic architecture of COVID-19
- Author
- Abd Elghafar MS
- Abdel-Aziz M
- Abdollahi H
- Abdullah T
- Abecasis GR
- Abedalthagafi M
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- Biscarini F
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- Uitterlinden AG
- Underwood SJ
- Vaghi M
- Valente S
- Valentino F
- van Blokland I
- van Heel D
- van Heel DA
- van Heel DA
- Van Singer M
- Vecchia M
- Veerapen K
- Venn LD
- Venturelli S
- Vergori A
- Verma A
- Verma SS
- Verzuri A
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- Villalonga JM
- Vincenti A
- Viollet RM
- Vivo OD
- Voide C
- Voide C
- Vollenweider P
- Vollenweider P
- von Hohenstaufen KA
- von Mering C
- Vonk JM
- Vulesevic B
- Wain LV
- Walker S
- Walters RK
- Wang J
- Wang X
- Wanying Z
- Warmerdam R
- Weiss ST
- Wicks SJ
- Willer C
- Williams AT
- Wilson DJ
- Wilson JF
- Wolford B
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- Wolford B
- Woolley AE
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- Wright J
- Wyllie DH
- Xue X
- Yadav A
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- Zanella I
- Zeberg H
- Zguro K
- Zhang M
- Zhao JH
- Zhou W
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- Zlatopolsky M
- zu Bentrup FM
- Zucchi P
- Zyndorf M
- Zöllner S
- Åsvold BO
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2022
- Field of study
A second update on mapping the human genetic architecture of COVID-19
- Author
- Abd Elghafar MS
- Abdel-Aziz M
- Abdelrazik M
- Abdullah MS
- Abe R
- Abe S
- Abel L
- Abel L
- Abernathy C
- Abraham R
- Abraheem A
- Abu Alragheb BO
- Abulail JA
- Acklery A
- Acosta-Herrera M
- Adachi T
- Adachi Y
- Adam R
- Adams C
- Adams K
- Adams N
- Adanini O
- Afifi N
- Afilalo J
- Afilalo M
- Afolabi D
- Afrasiabi Z
- Afset JE
- Agasou A
- Aghemo A
- Agravante K
- Agrawal A
- Agrawal S
- Aguado JM
- Aguilar C
- Aguilar SEV
- Aguilar-Salinas CA
- Aguilera-Albesa S
- Agüero D
- Ahmad HF
- Ahmad N
- Ahmadhaider N
- Ahmed A
- Ahmed C
- Ahram M
- Ai M
- Ain Q
- Aitkin E
- Akeroyd L
- Akhtar MN
- Akinkugbe O
- Al-Ani A
- Al-Ja’afreh MM
- Al-Kadash A
- Al-Kasasbeh MM
- Al-Moasseb H
- Al-Muftah W
- Al-Sarraj Y
- Alamer LM
- Alasdair F
- Alawneh FM
- Alawneh LM
- Albaiceta GM
- Albano G
- Albillos A
- Albrecht W
- Aldridge J
- Alexander P
- Alfonso J
- Alhousani TN
- Ali A
- Ali HH
- Ali IAM
- Ali S
- Aliberti S
- ALjalamdeh M
- Allan A
- Allan E
- Allan J
- Alldis Z
- Allen L
- Allen M
- Allen S
- Allen U
- Allibone S
- Allison KS
- Allouzy SK
- Ally SM
- Almadana V
- Almaden-Boyle C
- Almoguera B
- Alpuche-Aranda C
- AlRawashdeh TJ
- Alsafadi DB
- Alshaer W
- Alsoub FS
- Altabaibeh A
- Alvarez N
- Alvaro A
- Alzuraiqi MR
- Amamio M
- Aman NF
- Amin V
- Amiya S
- Ampuero J
- Anan R
- Anastasescu E
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- Andrew G
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- Andrews SJ
- Angelini C
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- Anumakonda V
- Anwer M
- Anzai T
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- Aquino-Gálvez A
- Arai D
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- Ortega-Paino E
- Ortiz AB
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- Williams D
- Williams E
- Williams E
- Williams G
- Williams H
- Williams J
- Williams K
- Williams M
- Williams P
- Williams S
- Williams T
- Willis C
- Willis H
- Wills M
- Willson J
- Wilson A
- Wilson DJ
- Wilson J
- Wilson JF
- Wiltfang J
- Winchester J
- Winkler TW
- Winmill H
- Winnard S
- Winter C
- Winter K
- Winter-Goodwin B
- Wittig M
- Witzke O
- Wolf-Roberts R
- Wolford BN
- Wong I
- Wong J
- Wong J
- Wood D
- Wood H
- Wood S
- Wood S
- Wood T
- Woodford C
- Woodruff M
- Woods L
- Woodward E
- Woodward J
- Woolcock M
- Woolley AE
- Worner R
- Worsley L
- Wray G
- Wren L
- Wreybrown C
- Wright C
- Wright DJ
- Wright J
- Wright M
- Wright S
- Wrobel N
- Wu Y
- Wulandari R
- Wylie K
- Wyllie DH
- Wynter I
- Xavier K
- Xue X
- Yagi K
- Yamada M
- Yamada Y
- Yamagata K
- Yamasaki M
- Yang J
- Yaspan B
- Yassen AM
- Yasui Y
- Yates B
- Yatomi M
- Ye C
- Yermakovich D
- Yeung RSM
- Yi X
- Yonekawa A
- Yoo S
- Yoon K
- Yoshida K
- Yoshida S
- Yoshida S
- Yoshida T
- Yoshihara T
- Yoshiya K
- Yoshiyama T
- Young M
- Yue F
- Yun N
- Yáñez CE
- Yáñez Z
- Zainulabid UA
- Zainy T
- Zak A
- Zaki A
- Zamikula J
- Zamudio IPM
- Zanella A
- Zapata-Contreras D
- Zapatamartinez M
- Zarate R
- Zarei N
- Zavaleta DAF
- Zawadzki P
- Zawati MH
- Zborowski AC
- Zeberg H
- Zechner M
- Zhang Q
- Zhao X
- Zheng C
- Zheng T
- Zhlawi HJ
- Zhlawi MWJ
- Zholdybayeva E
- Zhou W
- Zhu W
- Zitter L
- Zoller H
- Zongo O
- Zorloni C
- Zuñiga-Pacheco P
- Zárate RN
- Zúñiga-Ramos J
- Álvarez BG
- Ávila-Arcos MA
- Ávila-Arcos MC
- Özer O
- Überla K
- Þorsteinsdóttir U
- Publication venue
- Nature Research
- Publication date
- 21/06/2023
- Field of study