3,049 research outputs found

    L'avaluació de l'ensenyament universitari des d'un enfocament institucional

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    Cambio de paradigma metodológico en la Educación Superior: Exigencias que conlleva

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    Curricular and methodological reform of university education : a critical look at the construction of the European Higher Education

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    Concluida la fase de adaptación de las titulaciones al proceso de convergencia europea, y superados ya los primeros cursos de la nueva andadura, constatamos una opinión mayoritaria de rechazo a los nuevos planes de estudio cuestionando su oportunidad y coherencia. El objetivo del presente estudio ha sido analizar alguno de los factores que han condicionado el proceso de adaptación de las nuevas titulaciones en las dos cuestiones que se consideraban claves para promover el Espacio Europeo de Educación Superior: la renovación curricular y la innovación metodológica. Nuestro trabajo pretende ser una mirada crítica sobre cómo se ha gestionado este proceso identificando algunas de las debilidades del sistema universitario que han contribuido a que las instituciones no hayan aprovechado eficazmente las oportunidades que el marco normativo ofrecía para efectuar la reforma necesariaAfter the adaptation phase of university degrees to the process of European convergence and overcome since the first years of the new era, we find a high rate of rejection of the new curriculum, questioning its timeliness and consistency. The aim of this study was to analyze some of the factors that have constrained the process of adaptation of new Degrees in the two key issues that were considered to promote European Higher Education: curriculum renewal and methodological innovation. Our work pretending to be a critical look at how you have managed this process by identifying some of the weaknesses of the university system that have helped institutions from having effectively taken advantage of the opportunities offered by the regulatory framework necessary to effect refor

    Cytochrome c signalosome in mitochondria

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    Cytochrome c delicately tilts the balance between cell life (respiration) and cell death (apoptosis). Whereas cell life is governed by transient electron transfer interactions of cytochrome c inside the mitochondria, the cytoplasmic adducts of cytochrome c that lead to cell death are amazingly stable. Interestingly, the contacts of cytochrome c with its counterparts shift from the area surrounding the heme crevice for the redox complexes to the opposite molecule side when the electron flow is not necessary. The cytochrome c signalosome shows a higher level of regulation by post-translational modifications—nitration and phosphorylation—of the hemeprotein. Understanding protein interfaces, as well as protein modifications, would puzzle the mitochondrial cytochrome c-controlled pathways out and enable the design of novel drugs to silence the action of pro-survival and pro-apoptotic partners of cytochrome c.Spanish Ministry of Science and Innovation BFU2009-07190Andalusian Government BIO198 P08-CVI-387

    Hypercube algorithms on mesh connected multicomputers

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    A new methodology named CALMANT (CC-cube Algorithms on Meshes and Tori) for mapping a type of algorithm that we call CC-cube algorithm onto multicomputers with hypercube, mesh, or torus interconnection topology is proposed. This methodology is suitable when the initial problem can be expressed as a set of processes that communicate through a hypercube topology (a CC-cube algorithm). There are many important algorithms that fit into the CC-cube type. CALMANT is based on three different techniques: (a) the standard embedding to assign the processes of the algorithm to the nodes of the mesh multicomputer; (b) the communication pipelining technique to increase the level of communication parallelism inherent in the CC-cube algorithms; and (c) optimal message-scheduling algorithms proposed in this work in order to avoid conflicts and minimizing in this way the communication time. Although CALMANT is proposed for multicomputers with different interconnection network topologies, the paper only focuses on the particular case of meshes.Peer ReviewedPostprint (published version

    Cytochrome c: Surfing Off of the Mitochondrial Membrane on the Tops of Complexes III and IV

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    The proper arrangement of protein components within the respiratory electron transport chain is nowadays a matter of intense debate, since altering it leads to cell aging and other related pathologies. Here, we discuss three current views-the so-called solid, fluid and plasticity models-which describe the organization of the main membrane-embedded mitochondrial protein complexes and the key elements that regulate and/or facilitate supercomplex assembly. The soluble electron carrier cytochrome c has recently emerged as an essential factor in the assembly and function of respiratory supercomplexes. In fact, a 'restricted diffusion pathway' mechanism for electron transfer between complexes III and IV has been proposed based on the secondary, distal binding sites for cytochrome c at its two membrane partners recently discovered. This channeling pathway facilitates the surfing of cytochrome c on both respiratory complexes, thereby tuning the efficiency of oxidative phosphorylation and diminishing the production of reactive oxygen species. The well-documented post-translational modifications of cytochrome c could further contribute to the rapid adjustment of electron flow in response to changing cellular conditions.Spanish Ministry of Economy and Competitiveness (BFU2015-71017/BMC MINECO/FEDER and PGC2018-096049-B-I00 BIO/BMC MICINN/FEDER, EU

    A study of the communication cost of the FFT on torus multicomputers

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    The computation of a one-dimensional FFT on a c-dimensional torus multicomputer is analyzed. Different approaches are proposed which differ in the way they use the interconnection network. The first approach is based on the multidimensional index mapping technique for the FFT computation. The second approach starts from a hypercube algorithm and then embeds the hypercube onto the torus. The third approach reduces the communication cost of the hypercube algorithm by pipelining the communication operations. A novel methodology to pipeline the communication operations on a torus is proposed. Analytical models are presented to compare the different approaches. This comparison study shows that the best approach depends on the number of dimensions of the torus and the communication start-up and transfer times. The analytical models allow us to select the most efficient approach for the available machine.Peer ReviewedPostprint (published version

    An analysis on the effectiveness of Machine Translation Tools for the translation of medical texts from English to Spanish

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    Nowadays, translation has an important role in society, since it allows people to progress in knowledge in any field that may arise. For this reason, translation has become very usual and necessary. The objective of this project is to analyze MT systems in order to discover how reliable they are and to detect the main reasons why these systems may cause problems. Moreover, the result of this project solves possible doubts among translators and raises awareness about the use of these MT systems. Finally, readers will be able to observe the importance of following some procedures when dealing with a translation project and the relevance of facilitating a post-edition version to have a better understanding of the suggestions provided to improve the quality of the translation. It can also be useful for those people who do not really control the language used and want to seek information about this disease.Hoy en día la traducción es un aspecto muy importante en la sociedad, ya que permite progresar en conocimientos en cualquier ámbito que se presente. Por este motivo, la traducción es una tarea de gran importancia. El principal objetivo de este trabajo es analizar los sistemas de TA con el fin de descubrir cuan fiables son y detectar los principales motivos por los que estos sistemas pueden provocar problemas. Además, el resultado de este proyecto resuelve posibles dudas entre los traductores y da conciencia sobre el uso de estos sistemas de traducción automática. Finalmente, los lectores podrán observar la vitalidad de seguir unos procedimientos a la hora de afrontar una traducción y la importancia de facilitar una posedición para que se comprendan con mayor facilidad las sugerencias facilitadas para perfeccionar la traducción. Además, puede también servir a aquellas personas que desconozcan el idioma y deseen buscar información sobre esta enfermedad.Departamento de Filología InglesaGrado en Estudios Inglese

    Experiencias en el PARTNeR – ASAAF--UCM

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    Presentación de programa de formacion de ASAAF utilizando el proyecto PARTNeR

    Proyectos de ASAAF-UCM observando con PARTNeR

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    Conjunto de actividades formativas realizadas desde la Asociación ASAAF-UCM con el radiotelescopio del Proyecto PARTNeR, entre las que se incluyen: Elaboración de un proyecto científico propio, creación de un software propio de reducción automática de datos, presentación de resultados en congresos temáticos y revistas de divulgación
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