Auditory neuropathy in a patient exposed to xylene: case report

Objective: To report the case of an adult patient who developed auditory complaints following xylene exposure, and to review the literature on the effects of solvent exposure on hearing.Case report: The patient presented with a gradual deterioration in his ability to hear in difficult acoustic environments and also to hear complex sounds such as music, over a 40-year period. His symptoms began following exposure to the solvent xylene, and in the absence of any other risk factor. Our audiological investigations revealed normal otoacoustic emissions with absent auditory brainstem responses and absent acoustic reflexes in both ears, consistent with a diagnosis of bilateral auditory neuropathy. Central test results were also abnormal, indicating possible involvement of the central auditory pathway.Conclusions: To our knowledge, this is the first report of retrocochlear hearing loss following xylene exposure. The test results may provide some insight into the effect of xylene as an isolated agent on the human auditory pathway

Indirect Signs of the Peccei-Quinn Mechanism

In the Standard Model, the renormalization of the QCD vacuum angle $\theta$ is extremely tiny, and small $\theta$ is technically natural. In the general Standard Model effective field theory (SMEFT), however, $\Delta\theta$ is quadratically divergent, reflecting the fact that new sources of hadronic CP-violation typically produce $\mathcal O(1)$ threshold corrections to $\theta$. The observation of such CP-violating interactions would therefore be in tension with solutions to the strong CP problem in which $\theta=0$ is an ultraviolet boundary condition, pointing to the Peccei-Quinn mechanism as the explanation for why $\theta$ is small in the infrared. We study the quadratic divergences in $\theta$ arising from dimension-6 SMEFT operators and discuss the discovery prospects for these operators at electric dipole moment experiments, the LHC, and future proton-proton colliders.Comment: 27 pages, 3 figures. Comments welcome

Disk-Loss and Disk Renewal Phases in Classical Be Stars II. Detailed Analysis of Spectropolarimetric Data

In Wisniewski et al. 2010, paper I, we analyzed 15 years of spectroscopic and spectropolarimetric data from the Ritter and Pine Bluff Observatories of 2 Be stars, 60 Cygni and {\pi} Aquarii, when a transition from Be to B star occurred. Here we anaylize the intrinsic polarization, where we observe loop-like structures caused by the rise and fall of the polarization Balmer Jump and continuum V-band polarization being mismatched temporally with polarimetric outbursts. We also see polarization angle deviations from the mean, reported in paper I, which may be indicative of warps in the disk, blobs injected at an inclined orbit, or spiral density waves. We show our ongoing efforts to model time dependent behavior of the disk to constrain the phenomena, using 3D Monte Carlo radiative transfer codes.Comment: 2 pages, 6 figures, IAU Symposium 27

A Dynamic Approach to Addressing Observation-Minus-Forecast Mean Differences in a Land Surface Skin Temperature Data Assimilation System

In land data assimilation, bias in the observation-minus-forecast (O-F) residuals is typically removed from the observations prior to assimilation by rescaling the observations to have the same long-term mean (and higher-order moments) as the corresponding model forecasts. Such observation rescaling approaches require a long record of observed and forecast estimates, and an assumption that the O-F mean differences are stationary. A two-stage observation bias and state estimation filter is presented, as an alternative to observation rescaling that does not require a long data record or assume stationary O-F mean differences. The two-stage filter removes dynamic (nonstationary) estimates of the seasonal scale O-F mean difference from the assimilated observations, allowing the assimilation to correct the model for synoptic-scale errors without adverse effects from observation biases. The two-stage filter is demonstrated by assimilating geostationary skin temperature (Tsk) observations into the Catchment land surface model. Global maps of the O-F mean differences are presented, and the two-stage filter is evaluated for one year over the Americas. The two-stage filter effectively removed the Tsk O-F mean differences, for example the GOES-West O-F mean difference at 21:00 UTC was reduced from 5.1 K for a bias-blind assimilation to 0.3 K. Compared to independent in situ and remotely sensed Tsk observations, the two-stage assimilation reduced the unbiased Root Mean Square Difference (ubRMSD) of the modeled Tsk by 10 of the open-loop values

Using chirality to influence supramolecular gelation

Most low molecular weight gelators are chiral, with racemic mixtures often unable to form gels. Here, we show an example where all enantiomers, diastereomers and racemates of a single functionalized dipeptide can form gels. At high pH, different self-assembled aggregates are formed and these directly template the structures formed in the gel. Hence, solutions and gels with different properties can be accessed simply by varying the chirality. This opens up new design rules for the field

Critical Slowing-Down in SU(2)SU(2) Landau Gauge-Fixing Algorithms

We study the problem of critical slowing-down for gauge-fixing algorithms (Landau gauge) in $SU(2)$ lattice gauge theory on a $2$-dimensional lattice. We consider five such algorithms, and lattice sizes ranging from $8^{2}$ to $36^{2}$ (up to $64^2$ in the case of Fourier acceleration). We measure four different observables and we find that for each given algorithm they all have the same relaxation time within error bars. We obtain that: the so-called {\em Los Alamos} method has dynamic critical exponent $z \approx 2$, the {\em overrelaxation} method and the {\em stochastic overrelaxation} method have $z \approx 1$, the so-called {\em Cornell} method has $z$ slightly smaller than $1$ and the {\em Fourier acceleration} method completely eliminates critical slowing-down. A detailed discussion and analysis of the tuning of these algorithms is also presented.Comment: 40 pages (including 10 figures). A few modifications, incorporating referee's suggestions, without the length reduction required for publicatio

XMM Follow-Up Observations of Three Swift BAT-Selected Active Galactic Nuclei

We present XMM-Newton observations of three AGN taken as part of a hunt to find very heavily obscured Compton-thick AGN. For obscuring columns greater than 10^25 cm^-2, AGN are only visible at energies below 10 keV via reflected/scattered radiation, characterized by a flat power-law. We therefore selected three objects (ESO 417-G006, IRAS 05218-1212, and MCG -01-05-047) from the Swift BAT hard X-ray survey catalog with Swift X-ray Telescope XRT 0.5-10 keV spectra with flat power-law indices as candidate Compton-thick sources for follow-up observations with the more sensitive instruments on XMM-Newton. The XMM spectra, however, rule out reflection-dominated models based on the weakness of the observed Fe K-alpha lines. Instead, the spectra are well-fit by a model of a power-law continuum obscured by a Compton-thin absorber, plus a soft excess. This result is consistent with previous follow-up observations of two other flat-spectrum BAT-detected AGN. Thus, out of the six AGN in the 22-month BAT catalog with apparently flat Swift XRT spectra, all five that have had follow-up observations are not likely Compton-thick. We also present new optical spectra of two of these objects, IRAS 05218-1212 and MCG -01-05-047. Interestingly, though both these AGN have similar X-ray spectra, their optical spectra are completely different, adding evidence against the simplest form of the geometric unified model of AGN. IRAS 05218-1212 appears in the optical as a Seyfert 1, despite the ~8.5x10^22 cm^-2 line-of-sight absorbing column indicated by its X-ray spectrum. MCG -01-05-047's optical spectrum shows no sign of AGN activity; it appears as a normal galaxy.Comment: 18 pages including 4 figures, accepted by Ap

Estudo da suscetibilidade ao escurecimento por radiação gama de quartzo róseo-leitoso da província pegmatítica da Borborema

Este estudo considera as transformações induzidas pela radiação γ sobre os defeitos estruturais em quartzo róseo e leitoso da Província Pegmatítica da Borborema (Paraíba e Rio Grande do Norte, Brasil). Amostras de coloração rósea e leitosa foram irradiadas com doses de raios γ (60Co) entre 0,5 e 96 kGy. Defeitos pontuais relacionados às impurezas de Al, Ge, Li e grupos OH foram caracterizados por espectroscopias ultravioleta visível e infravermelha e ressonância paramagnética eletrônica, antes e após a irradiação. A espectrometria de massa com plasma indutivamente acoplado foi empregada para quantificar as concentrações de Al, Li, Ge, Fe, Ti e outras impurezas em fragmentos de diferentes tonalidades. Constatou-se que os defeitos [AlO4]0, [AlO4/H]0 e [GeO4/Li]0 são formados pela dissociação dos defeitos [AlO4/Li]0 e [Li-OH], a partir de doses de 0,5 kGy. A diminuição do sinal da ressonância paramagnética eletrônica do centro [GeO4/Li]0 e a formação de centros E'1 perturbados por Ge para doses acima de 8 kGy confirmou a grande mobilidade dos íons Li+ pela estrutura do quartzo. O aumento da população de defeitos [AlO4]0 e o consequente escurecimento das amostras foi semelhante para ambos os tipos de quartzo. Análises preliminares por microscopia eletrônica mostraram a presença de fibras nanométricas apenas no resíduo da digestão ácida de amostras róseas, indicando que a coloração rósea do quartzo da Província Pegmatítica da Borborema está provavelmente relacionada às inclusões de dumortierita

Advances in Assimilation of Satellite-Based Passive Microwave Observations for Soil-Moisture Estimation

Satellite-based microwave measurements have long shown potential to provide global information about soil moisture. The European Space Agency (ESA) Soil Moisture and Ocean Salinity (SMOS, [1]) mission as well as the future National Aeronautics and Space Administration (NASA) Soil Moisture Active and Passive (SMAP, [2]) mission measure passive microwave emission at L-band frequencies, at a relatively coarse (40 km) spatial resolution. In addition, SMAP will measure active microwave signals at a higher spatial resolution (3 km). These new L-band missions have a greater sensing depth (of -5cm) compared with past and present C- and X-band microwave sensors. ESA currently also disseminates retrievals of SMOS surface soil moisture that are derived from SMOS brightness temperature observations and ancillary data. In this research, we address two major challenges with the assimilation of recent/future satellite-based microwave measurements: (i) assimilation of soil moisture retrievals versus brightness temperatures for surface and root-zone soil moisture estimation and (ii) scale-mismatches between satellite observations, models and in situ validation data