Polyamide profiles of porcine milk and of intestinal tissue of pigs during suckling.

Previous studies have suggested that luminal polyamines can directly influence intestinal differentiation of neonatal rats. The present investigation has demonstrated the presence of high levels of polyamines in porcine milk and in the intestinal tissues of suckling pigs. The quantities of polyamines in sow's milk sampled between weeks 1 and 8 of lactation were determined using high performance liquid chromatography (HPLC). The concentration of milk spermidine (SPD) remained constant over the first three to four weeks of lactation but increased four-fold between weeks 4 and 7. Neither putrescine nor spermine (SPN) were detected in any of the milk samples. During intestinal development the mucosal SPD/SPN ratio was elevated between weeks 1 and 3, and weeks 5 and 7. The latter period of increase corresponded with the surge in milk SPD concentration. It is suggested that milk SPD is taken up from the intestinal lumen and is involved in potentiating intestinal differentiation during the latter part of the suckling period

Improved Bounds on the Phase Transition for the Hard-Core Model in 2-Dimensions

For the hard-core lattice gas model defined on independent sets weighted by an activity $\lambda$, we study the critical activity $\lambda_c(\mathbb{Z}^2)$ for the uniqueness/non-uniqueness threshold on the 2-dimensional integer lattice $\mathbb{Z}^2$. The conjectured value of the critical activity is approximately $3.796$. Until recently, the best lower bound followed from algorithmic results of Weitz (2006). Weitz presented an FPTAS for approximating the partition function for graphs of constant maximum degree $\Delta$ when $\lambda<\lambda_c(\mathbb{T}_\Delta)$ where $\mathbb{T}_\Delta$ is the infinite, regular tree of degree $\Delta$. His result established a certain decay of correlations property called strong spatial mixing (SSM) on $\mathbb{Z}^2$ by proving that SSM holds on its self-avoiding walk tree $T_{\mathrm{saw}}^\sigma(\mathbb{Z}^2)$ where $\sigma=(\sigma_v)_{v\in \mathbb{Z}^2}$ and $\sigma_v$ is an ordering on the neighbors of vertex $v$. As a consequence he obtained that $\lambda_c(\mathbb{Z}^2)\geq\lambda_c( \mathbb{T}_4) = 1.675$. Restrepo et al. (2011) improved Weitz's approach for the particular case of $\mathbb{Z}^2$ and obtained that $\lambda_c(\mathbb{Z}^2)>2.388$. In this paper, we establish an upper bound for this approach, by showing that, for all $\sigma$, SSM does not hold on $T_{\mathrm{saw}}^\sigma(\mathbb{Z}^2)$ when $\lambda>3.4$. We also present a refinement of the approach of Restrepo et al. which improves the lower bound to $\lambda_c(\mathbb{Z}^2)>2.48$.Comment: 19 pages, 1 figure. Polished proofs and examples compared to earlier versio

Improved lower bounds for the ground-state energy of many-body systems

New lower bounds for the binding energy of a quantum-mechanical system of interacting particles are presented. The new bounds are expressed in terms of two-particle quantities and improve the conventional bounds of the Hall-Post type. They are constructed by considering not only the energy in the two-particle system, but also the structure of the pair wave function. We apply the formal results to various numerical examples, and show that in some cases dramatic improvement over the existing bounds is reached.Comment: 29 pages, 5 figures, to be published in Phys. Rev.

Probing the nucleon structure with CLAS

An overview of recent results with CLAS is presented with emphasis on nucleon resonance studies, nucleon spin structure, and generalized parton distributions.Comment: Plenary talk presented at NSTAR 2007, Bonn, German

Absence seizures as resetting mechanisms of brain dynamics

To understand the increase in age-related incidence and frequency of absence seizures in the rat brain, we investigated the effect of these seizures on brain dynamics. This paper puts forward the hypothesis that age-related differences in the expression of absence seizures are associated with the ability of the seizures to reset brain dynamics

Validation of low anterior resection syndrome score in Brazil with Portuguese

Purpose This study was performed to investigate the convergent validity, discriminative validity, and reliability of the Brazilian version of the low anterior resection syndrome (LARS) score in a population with low educational and socioeconomic levels. Methods The LARS score was translated into the Portuguese language by forward- and back-translation procedures. In total, 127 patients from a public hospital in Brazil completed the questionnaires. The convergent validity was tested by comparing the LARS score with the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core Module 30 (QLQ-C30) and with patients’ self-reported quality of life. For the discriminative validity, we tested the ability of the score to differentiate among subgroups of patients regarding neoadjuvant radiotherapy, type of surgery, and tumor distance from the anal verge. The test-retest reliability was investigated in a subgroup of 36 patients who responded to the survey twice in 2 weeks. Results The LARS score demonstrated a strong correlation with 5 of 6 items from the EORTC QLQ-C30 (P<0.05) and good concordance with patients’ self-reported quality of life (95.3%), confirming the convergent validity. The score was able to discriminate between subgroups of patients with different clinical characteristics related to LARS (P<0.001). The agreement between the test and retest showed that 86.1% of the patients remained in the same LARS category, and there was no significant difference between the LARS score numerical values (P=0.80), indicating good reliability overall. Conclusion The Brazilian version of the LARS score is a valid and reliable instrument to assess postoperative bowel function in a population with low educational and socioeconomic levels

The effect of multiple deformations on the formation of ultrafine grained steels

A C-Mn-Nb-Ti steel was deformed by hot torsion to study ultrafine ferrite formation through dynamic strain-induced transformation (DSIT) in conjunction with air cooling. A systematic study was carried out first to evaluate the effect of deformation temperature and prior austenite grain size on the critical strain for ultrafine ferrite formation (&epsilon; C,UFF) through single-pass deformation. Then, multiple deformations in the nonrecrystallization region were used to study the effect of thermomechanical parameters (i.e., strain, deformation temperature, etc.) on &epsilon; C,UFF. The multiple deformations in the nonrecrystallization region significantly reduced &epsilon; C,UFF, although the total equivalent strain for a given thermomechanical condition was higher than that required in single-pass deformation. The current study on a Ni-30Fe austenitic model alloy revealed that laminar microband structures were the key intragranular defects in the austenite for nucleation of ferrite during the hot torsion test. The microbands were refined and overall misorientation angle distribution increased with a decrease in the deformation temperature for a given thermomechanical processing condition. For nonisothermal multipass deformation, there was some contribution to the formation of high-angle microband boundaries from strains at higher temperature, although the strains were not completely additive.<br /

Virtual Compton Scattering and Neutral Pion Electroproduction in the Resonance Region up to the Deep Inelastic Region at Backward Angles

We have made the first measurements of the virtual Compton scattering (VCS) process via the H$(e,e'p)\gamma$ exclusive reaction in the nucleon resonance region, at backward angles. Results are presented for the $W$-dependence at fixed $Q^2=1$ GeV$^2$, and for the $Q^2$-dependence at fixed $W$ near 1.5 GeV. The VCS data show resonant structures in the first and second resonance regions. The observed $Q^2$-dependence is smooth. The measured ratio of H$(e,e'p)\gamma$ to H$(e,e'p)\pi^0$ cross sections emphasizes the different sensitivity of these two reactions to the various nucleon resonances. Finally, when compared to Real Compton Scattering (RCS) at high energy and large angles, our VCS data at the highest $W$ (1.8-1.9 GeV) show a striking $Q^2$- independence, which may suggest a transition to a perturbative scattering mechanism at the quark level.Comment: 20 pages, 8 figures. To appear in Phys.Rev.