4,313 research outputs found

    Optimal correction of concatenated fault-tolerant quantum codes

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    We present a method of concatenated quantum error correction in which improved classical processing is used with existing quantum codes and fault-tolerant circuits to more reliably correct errors. Rather than correcting each level of a concatenated code independently, our method uses information about the likelihood of errors having occurred at lower levels to maximize the probability of correctly interpreting error syndromes. Results of simulations of our method applied to the [[4,1,2]] subsystem code indicate that it can correct a number of discrete errors up to half of the distance of the concatenated code, which is optimal.Comment: 7 pages, 2 figures, published versio

    HI: haplotype improver using paired-end short reads

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    Summary: We present a program to improve haplotype reconstruction by incorporating information from paired-end reads, and demonstrate its utility on simulated data. We find that given a fixed coverage, longer reads (implying fewer of them) are preferable

    In-Situ Infrared Transmission Study of Rb- and K-Doped Fullerenes

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    We have measured the four IR active C60C_{60} molecular vibrations in MxC60M_{x}C_{60} (M=K,Rb)(M = K, Rb) as a function of doping xx. We observe discontinuous changes in the vibrational spectra showing four distinct phases (presumably x=0,3,4x = 0, 3, 4, and 6). The 1427cm11427cm^{-1} and 576cm1576cm^{-1} modes show the largest changes shifting downward in frequency in four steps as the doping increases. Several new very weak modes are visible in the x=6x=6 phase and are possibly Raman modes becoming weakly optically active. We present quantitative fits of the data and calculate the electron-phonon coupling of the 1427cm11427cm^{-1} IR mode.Comment: 3 pages, Figure 1 included, 3 more figures available by request. REVTEX v3.0 IRC60DO

    Structure and properties of a novel fulleride Sm6C60

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    A novel fulleride Sm6C60 has been synthesized using high temperature solid state reaction. The Rietveld refinement on high resolution synchrotron X-ray powder diffraction data shows that Sm6C60 is isostructural with body-centered cubic A6C60 (A=K, Ba). Raman spectrum of Sm6C60 is similar to that of Ba6C60, and the frequencies of two Ag modes in Sm6C60 are nearly the same as that of Ba6C60, suggesting that Sm is divalent and hybridization between C60 molecules and the Sm atom could exist in Sm6C60. Resistivity measurement shows a weak T-linear behavior above 180 K, the transport at low temperature is mainly dominated by granular-metal theory.Comment: 9 pages, 3 figures, submitted to Phys. Rev. B (March 12, 1999

    Analysis of the rotation period of asteroids (1865) Cerberus, (2100) Ra-Shalom, and (3103) Eger - search for the YORP effect

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    The spin state of small asteroids can change on a long timescale by the Yarkovsky-O'Keefe-Radzievskii-Paddack (YORP) effect, the net torque that arises from anisotropically scattered sunlight and proper thermal radiation from an irregularly-shaped asteroid. The secular change in the rotation period caused by the YORP effect can be detected by analysis of asteroid photometric lightcurves. We analyzed photometric lightcurves of near-Earth asteroids (1865) Cerberus, (2100) Ra-Shalom, and (3103) Eger with the aim to detect possible deviations from the constant rotation caused by the YORP effect. We carried out new photometric observations of the three asteroids, combined the new lightcurves with archived data, and used the lightcurve inversion method to model the asteroid shape, pole direction, and rotation rate. The YORP effect was modeled as a linear change in the rotation rate in time d\omega /dt. Values of d\omega/ dt derived from observations were compared with the values predicted by theory. We derived physical models for all three asteroids. We had to model Eger as a nonconvex body because the convex model failed to fit the lightcurves observed at high phase angles. We probably detected the acceleration of the rotation rate of Eger d\omega / dt = (1.4 +/- 0.6) x 10^{-8} rad/d (3\sigma error), which corresponds to a decrease in the rotation period by 4.2 ms/yr. The photometry of Cerberus and Ra-Shalom was consistent with a constant-period model, and no secular change in the spin rate was detected. We could only constrain maximum values of |d\omega / dt| < 8 x 10^{-9} rad/d for Cerberus, and |d\omega / dt| < 3 x 10^{-8} rad/d for Ra-Shalom

    Analysis of ChIP-seq data via Bayesian finite mixture models with a non-parametric component

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    In large discrete data sets which requires classification into signal and noise components, the distribution of the signal is often very bumpy and does not follow a standard distribution. Therefore the signal distribution is further modelled as a mixture of component distributions. However, when the signal component is modelled as a mixture of distributions, we are faced with the challenges of justifying the number of components and the label switching problem (caused by multimodality of the likelihood function). To circumvent these challenges, we propose a non-parametric structure for the signal component. This new method is more efficient in terms of precise estimates and better classifications. We demonstrated the efficacy of the methodology using a ChIP-sequencing data set

    Big Data: Astronomical or Genomical?

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    Genomics is a Big Data science and is going to get much bigger, very soon, but it is not known whether the needs of genomics will exceed other Big Data domains. Projecting to the year 2025, we compared genomics with three other major generators of Big Data: astronomy, YouTube, and Twitter. Our estimates show that genomics is a "four-headed beast"-it is either on par with or the most demanding of the domains analyzed here in terms of data acquisition, storage, distribution, and analysis. We discuss aspects of new technologies that will need to be developed to rise up and meet the computational challenges that genomics poses for the near future. Now is the time for concerted, community-wide planning for the "genomical" challenges of the next decade

    A look at the anatomy educator job market: anatomists remain in short supply

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    In 2002, a widely publicized report projected an anatomy educator shortage based on department chairpersons' perceptions. Now, 17 years later, the question lingers: “Does an anatomy educator shortage persist and, if so, how severe is the shortage?” Trends in the number, type, and fill rate of anatomy educator job openings were explored by analyzing job posting in the United States over the past two years. A survey was distributed to leaders of anatomy‐related departments in the United States, Canada, and European Union. Most departmental leaders who responded (65% or more) from the United States/Canada (n = 81) and the European Union (n = 52) anticipate they will have “moderate” to “great” difficulty hiring anatomy educators in gross anatomy, histology, and embryology over the next five years. Within the United States, the number of anatomy educator job postings at medical schools more than doubled from at least 21 postings in 2017 to 52 postings in 2018. Twenty‐one percent of postings between 2017 and 2018 were never filled. While the number of anatomy educator openings within the United States/Canada is perceived to remain in a steady state for the next five years, the European Union estimates a five‐fold increase in the number of openings. Departmental leaders prioritize anatomy educator applicants who have teaching experience (mean ± SD = 4.64 ± 0.84 on five‐point Likert scale), versatility in teaching multiple anatomy disciplines (3.93 ± 1.07), and flexibility in implementing various teaching pedagogies (3.69 ± 1.17). Collectively, these data suggest the shortage of anatomy educators continues in the United States/Canada and the European Union

    Cloud type comparisons of AIRS, CloudSat, and CALIPSO cloud height and amount

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    The precision of the two-layer cloud height fields derived from the Atmospheric Infrared Sounder (AIRS) is explored and quantified for a five-day set of observations. Coincident profiles of vertical cloud structure by CloudSat, a 94 GHz profiling radar, and the Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observation (CALIPSO), are compared to AIRS for a wide range of cloud types. Bias and variability in cloud height differences are shown to have dependence on cloud type, height, and amount, as well as whether CloudSat or CALIPSO is used as the comparison standard. The CloudSat-AIRS biases and variability range from &amp;minus;4.3 to 0.5&amp;plusmn;1.2&amp;ndash;3.6 km for all cloud types. Likewise, the CALIPSO-AIRS biases range from 0.6&amp;ndash;3.0&amp;plusmn;1.2&amp;ndash;3.6 km (&amp;minus;5.8 to &amp;minus;0.2&amp;plusmn;0.5&amp;ndash;2.7 km) for clouds &amp;ge;7 km (&amp;lt;7 km). The upper layer of AIRS has the greatest sensitivity to Altocumulus, Altostratus, Cirrus, Cumulonimbus, and Nimbostratus, whereas the lower layer has the greatest sensitivity to Cumulus and Stratocumulus. Although the bias and variability generally decrease with increasing cloud amount, the ability of AIRS to constrain cloud occurrence, height, and amount is demonstrated across all cloud types for many geophysical conditions. In particular, skill is demonstrated for thin Cirrus, as well as some Cumulus and Stratocumulus, cloud types infrared sounders typically struggle to quantify. Furthermore, some improvements in the AIRS Version 5 operational retrieval algorithm are demonstrated. However, limitations in AIRS cloud retrievals are also revealed, including the existence of spurious Cirrus near the tropopause and low cloud layers within Cumulonimbus and Nimbostratus clouds. Likely causes of spurious clouds are identified and the potential for further improvement is discussed

    Evidence for MBM_B and MCM_C phases in the morphotropic phase boundary region of (1x)[Pb(Mg1/3Nb2/3)O3]xPbTiO3(1-x)[Pb(Mg_{1/3}Nb_{2/3})O_3]-xPbTiO_3 : A Rietveld study

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    We present here the results of the room temperature dielectric constant measurements and Rietveld analysis of the powder x-ray diffraction data on (1x)[Pb(Mg1/3Nb2/3)O3]xPbTiO3(1-x)[Pb(Mg_{1/3}Nb_{2/3})O_3]-xPbTiO_3(PMN-xxPT) in the composition range 0.20x0.450.20 \leq x \leq 0.45 to show that the morphotropic phase boundary (MPB) region contains two monoclinic phases with space groups Cm (or MBM_B type) and Pm (or MCM_C type) stable in the composition ranges 0.27x0.300.27 \leq x \leq 0.30 and 0.31x0.340.31 \leq x \leq 0.34, respectively. The structure of PMN-xxPT in the composition ranges 0x0 \leq x \leq 0.26, and 0.35x10.35 \leq x \leq1 is found to be rhombohedral (R3m) and tetragonal (P4mm), respectively. These results are compared with the predictions of Vanderbilt & Cohen's theory.Comment: 20 pages, 11 pdf figure
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