Humans in Space: Summarizing the Medico-Biological Results of the Space Shuttle Program

As we celebrate the 50th anniversary of Gagarin's flight that opened the era of Humans in Space we also commemorate the 30th anniversary of the Space Shuttle Program (SSP) which was triumphantly completed by the flight of STS-135 on July 21, 2011. These were great milestones in the history of Human Space Exploration. Many important questions regarding the ability of humans to adapt and function in space were answered for the past 50 years and many lessons have been learned. Significant contribution to answering these questions was made by the SSP. To ensure the availability of the Shuttle Program experiences to the international space community NASA has made a decision to summarize the medico-biological results of the SSP in a fundamental edition that is scheduled to be completed by the end of 2011 beginning 2012. The goal of this edition is to define the normal responses of the major physiological systems to short-duration space flights and provide a comprehensive source of information for planning, ensuring successful operational activities and for management of potential medical problems that might arise during future long-term space missions. The book includes the following sections: 1. History of Shuttle Biomedical Research and Operations; 2. Medical Operations Overview Systems, Monitoring, and Care; 3. Biomedical Research Overview; 4. System-specific Adaptations/Responses, Issues, and Countermeasures; 5. Multisystem Issues and Countermeasures. In addition, selected operational documents will be presented in the appendices. The chapters are written by well-recognized experts in appropriate fields, peer reviewed, and edited by physicians and scientists with extensive expertise in space medical operations and space-related biomedical research. As Space Exploration continues the major question whether humans are capable of adapting to long term presence and adequate functioning in space habitats remains to be answered We expect that the comprehensive review of the medico-biological results of the SSP along with the data collected during the missions on the space stations (Mir and ISS) provides a good starting point in seeking the answer to this question

A method to disentangle single- and multi-meson production in missing mass spectra from quasi-free pn --> pn X reactions

The separation of contributions from multi- and single-meson production in the missing mass spectrum of the quasi-free pn --> pnX reaction constitutes a~challenging task when the reaction is studied close to threshold. This is especially true if the resolution of the mass determination is comparable with the excess energy and if the investigated signal appears close to the kinematical limit. In this article we outline a method which permits the extraction of the signal originating from the creation of a single meson without the necessity of conducting model-dependent simulations. For the pd --> pnXp(spectator) reactions, the method allows one to combine events corresponding to multi-meson production at various excess energies with respect to the pn --> pn meson process, and hence leads to an increase of the statistics needed for the determination of the shape of the multi-meson background. As an example of the application of the method, we demonstrate that the evaluation of the data from the pd --> pnXp(sp) process according to the described technique enables one to extract a signal of the pn --> pn eta reaction whose shape is consistent with expectations, supporting the correctness and usefulness of the method introduced.Comment: 14 pages, 10 figure

Precise 3D track reconstruction algorithm for the ICARUS T600 liquid argon time projection chamber detector

Liquid Argon Time Projection Chamber (LAr TPC) detectors offer charged particle imaging capability with remarkable spatial resolution. Precise event reconstruction procedures are critical in order to fully exploit the potential of this technology. In this paper we present a new, general approach of three-dimensional reconstruction for the LAr TPC with a practical application to track reconstruction. The efficiency of the method is evaluated on a sample of simulated tracks. We present also the application of the method to the analysis of real data tracks collected during the ICARUS T600 detector operation with the CNGS neutrino beam.Comment: Submitted to Advances in High Energy Physic

Underground operation of the ICARUS T600 LAr-TPC: first results

Open questions are still present in fundamental Physics and Cosmology, like the nature of Dark Matter, the matter-antimatter asymmetry and the validity of the particle interaction Standard Model. Addressing these questions requires a new generation of massive particle detectors exploring the subatomic and astrophysical worlds. ICARUS T600 is the first large mass (760 ton) example of a novel detector generation able to combine the imaging capabilities of the old famous "bubble chamber" with an excellent energy measurement in huge electronic detectors. ICARUS T600 now operates at the Gran Sasso underground laboratory, studying cosmic rays, neutrino oscillation and proton decay. Physical potentialities of this novel telescope are presented through few examples of neutrino interactions reconstructed with unprecedented details. Detector design and early operation are also reported.Comment: 14 pages, 8 figures, 2 tables. Submitted to Jins

Double-Pionic Fusion of Nuclear Systems and the ABCEffect -- Aproaching a Puzzle by Exclusive and Kinematically Complete Measurements

The ABC effect - a puzzling low-mass enhancement in the $\pi\pi$ invariant mass spectrum - is well-known from inclusive measurements of two-pion production in nuclear fusion reactions. Here we report on first exclusive and kinematically complete measurements of the most basic double pionic fusion reaction $pn \to d \pi^0\pi^0$ at 1.03 and 1.35 GeV. The measurements, which have been carried out at CELSIUS-WASA, reveal the ABC effect to be a $(\pi\pi)_{I=L=0}$ channel phenomenon associated with both a resonance-like energy dependence in the integral cross section and the formation of a $\Delta\Delta$ system in the intermediate state. A corresponding simple s-channel resonance ansatz provides a surprisingly good description of the data

Precision measurement of the neutrino velocity with the ICARUS detector in the CNGS beam

During May 2012, the CERN-CNGS neutrino beam has been operated for two weeks for a total of 1.8 10^17 pot in bunched mode, with a 3 ns narrow width proton beam bunches, separated by 100 ns. This tightly bunched beam structure allows a very accurate time of flight measurement of neutrinos from CERN to LNGS on an event-by-event basis. Both the ICARUS-T600 PMT-DAQ and the CERN-LNGS timing synchronization have been substantially improved for this campaign, taking ad-vantage of additional independent GPS receivers, both at CERN and LNGS as well as of the deployment of the "White Rabbit" protocol both at CERN and LNGS. The ICARUS-T600 detector has collected 25 beam-associated events; the corresponding time of flight has been accurately evaluated, using all different time synchronization paths. The measured neutrino time of flight is compatible with the arrival of all events with speed equivalent to the one of light: the difference between the expected value based on the speed of light and the measured value is tof_c - tof_nu = (0.10 \pm 0.67stat. \pm 2.39syst.) ns. This result is in agreement with the value previously reported by the ICARUS collaboration, tof_c - tof_nu = (0.3 \pm 4.9stat. \pm 9.0syst.) ns, but with improved statistical and systematic errors.Comment: 21 pages, 13 figures, 1 tabl

Exclusive Measurements of pp -> dpi+pi0: Double-Pionic Fusion without ABC Effect

Exclusive measurements of the reaction pp -> dpi+pi0 have been carried out at T_p = 1.1 GeV at the CELSIUS storage ring using the WASA detector. The isovector pi+pi0 channel exhibits no enhancement at low invariant pipi masses, i. e. no ABC effect. The differential distributions are in agreement with the conventional t-channel Delta-Delta excitation process, which also accounts for the observed energy dependence of the total cross section. This is an update of a previously published version -- see important note at the end of the article

The ICARUS T600 Experiment in the Gran Sasso Underground Laboratory

With a mass of about 600 tons of Liquid Argon (LAr), the ICARUS T600 detector is the biggest, up to now, LAr Time Projection Chamber (TPC). Following its successful test run, on the Earth surface, in Pavia (Italy) in 2001, the detector is now very close to start data taking in the Gran Sasso underground laboratory. The main features of the LAr TPC technique, together with a short discussion of some of the ICARUS T600 test run results, are presented in this paper

New Measurements of Upsilon(1S) Decays to Charmonium Final States

Using substantially larger data samples collected by the CLEO III detector, we report on new measurements of the decays of Upsilon(1S) to charmonium final states, including J/Psi, psi(2S), and chi_cJ. The latter two are first observations of these decays. We measure the branching fractions as follows: B(Y(1S)--> J/Psi+X)=(6.4+-0.4+-0.6)x10^-4, B(Y(1S)--> psi(2S)+X)/B(Y(1S)--> J/Psi+X)=0.41+-0.11+-0.08, B(Y(1S)--> chi_c1+X)/B(Y(1S)--> J/Psi+X)=0.35+-0.08+-0.06, B(Y(1S)--> chi_c2+X)/B(Y(1S)--> J/Psi+X)=0.52+-0.12+-0.09, and B(Y(1S)--> chi_c0+X)/B(Y(1S)--> J/Psi+X)<7.4% at 90% confidence level. We also report on the momentum and angular spectra of J/Psi's in Upsilon(1S) decay. The results are compared to predictions of the color octet and color singlet models.Comment: 27 pages postscript,also available through http://w4.lns.cornell.edu/public/CLNS/, submitted to PR