The free energy of biomembrane and nerve excitation and the role of anesthetics

In the electromechanical theory of nerve stimulation, the nerve impulse consists of a traveling region of solid membrane in a liquid environment. Therefore, the free energy necessary to stimulate a pulse is directly related to the free energy difference necessary to induce a phase transition in the nerve membrane. It is a function of temperature and pressure, and it is sensitively dependent on the presence of anesthetics which lower melting transitions. We investigate the free energy difference of solid and liquid membrane phases under the influence of anesthetics. We calculate stimulus-response curves of electromechanical pulses and compare them to measured stimulus-response profiles in lobster and earthworm axons. We also compare them to stimulus-response experiments on human median nerve and frog sciatic nerve published in the literature.Comment: 10 pages, 6 figure

Is periodontitis and its treatment capable of changing the quality of life of a patient?

While clinical indicators, or so-called surrogate outcomes in periodontology, allow us to assess periodontal health and evaluate outcomes of periodontal therapy from a clinician's perspective, they cannot be used to evaluate patients' subjective perceptions of their health status or satisfaction with the received treatment. These can be assessed through patient-based outcomes, such as quality of life. The aim of this paper is to give an overview of the multidimensional concept of oral health-related quality of life (OHRQoL), its measures and association with plaque-induced, inflammatory periodontal diseases. Periodontitis and its clinical consequences, such as tooth loss, have a considerable negative effect on OHRQoL, while periodontal treatment and alleviation of the symptoms can lead to improvement in OHRQoL. Implant rehabilitation of missing teeth also seems to positively influence OHRQo

What Yer Can\u27t Get Yer Got to do Without / music by John F. Rourke; words by N.D. Mc Donnell

Cover: drawing of a smiling face of an African American male; Publisher: Henry Crey Music Co. (Boston)https://egrove.olemiss.edu/sharris_b/1072/thumbnail.jp

When Uncle Joe Plays a Rag on His Old Banjo / music by Theodor Morse; words by D. A. Esrom

https://egrove.olemiss.edu/sharris_c/1042/thumbnail.jp

Creating space for facilitated music performance: gesture controlled sound for users with complex disabilities

Musical interactions have the potential to increase emotional well-being, self-confidence and self-motivation. However, the ability to actively participate in creative activities involving music performance has so far been difficult for users with complex disabilities. This paper discusses placing a technology probe, using gesture based musical controls, in an existing music technology project for users with complex disabilities (conditions which affect both cognitive and motor abilities of an individual). The focus is on understanding the needs of this user group in a participatory design approach for creative music technologies that allow for tailored accessibility. Outcomes from this research show that many multi-level social interactions surrounding the technology, users, audience, and any third party facilitators exist in the context of ‘facilitated performance’. Results suggest that including facilitators in the design of Digital Musical Instruments (DMIs) could allow for improved accessibility for users with complex disabilities

Filosax: A Dataset of Annotated Jazz Saxophone Recordings

The Filosax dataset is a large collection of specially commissioned recordings of jazz saxophonists playing with commercially available backing tracks. Five participants each recorded themselves playing the melody, interpreting a transcribed solo and improvising on 48 tracks, giving a total of around 24 hours of audio data. The solos are annotated both as individual note events with physical timing, and as sheet music with a metrical interpretation of the timing. In this paper, we outline the criteria used for choosing and sourcing the repertoire, the recording process and the semi-automatic transcription pipeline. We demonstrate the use of the dataset to analyse musical phenomena such as swing timing and dynamics of typical musical figures, as well as for training a source activity detection system and predicting expressive characteristics. Other potential applications include the modelling of jazz improvisation, performer identification, automatic music transcription, source separation and music generation

REAL-TIME PHYSICAL MODEL FOR SYNTHESIS OF SWORD SWING SOUNDS

Sword sounds are synthesised by physical models in real- time. A number of compact sound sources are used along the length of the sword which replicate the swoosh sound when swung through the air. Listening tests are carried out which reveal a model with reduced physics is perceived as more authentic. The model is further developed to be controlled by a Wii Controller and successfully extended to include sounds of a baseball bat and golf club