253 research outputs found
Preliminary measurements of lumbar spine kinematics and stiffness
The purpose of the presented study was the experimental measurement of lumbar spine stiffness and its range of motion. The dependence of torsion moment of lumbar spine segment on deflection of flexion, extension and torsion was observed during experiments. Stiffness of spine segment was determined from measured data. Human lumbar spine was used for verification of the experimental technique. The sample consisted of one lumbar vertebrae composed by five vertebral bodies and four intervertebral discs. All muscles were removed, however all ligaments were preserved. Experiments were ca rried out on the test system MTS 858.2 MiniBionix, where loading by axial force and torsion moment is possible at the same time. Special Modular Bionix Spine Test Fixator, attached to the test system was used for the measurements. Loading was controlled kinematically (gradual turning) by keeping the axial force equal zero. Measurement was timedependent. The results of these experiments are going to be used as input data for creating a model of artificial lumbar spine and new type of artificial disc replacement
Quasiperiodic oscillations in a strong gravitational field around neutron stars testing braneworld models
The strong gravitational field of neutron stars in the brany universe could
be described by spherically symmetric solutions with a metric in the exterior
to the brany stars being of the Reissner-Nordstrom type containing a brany
tidal charge representing the tidal effect of the bulk spacetime onto the star
structure. We investigate the role of the tidal charge in orbital models of
high-frequency quasiperiodic oscillations (QPOs) observed in neutron star
binary systems. We focus on the relativistic precession model. We give the
radial profiles of frequencies of the Keplerian (vertical) and radial epicyclic
oscillations. We show how the standard relativistic precession model modified
by the tidal charge fits the observational data, giving estimates of the
allowed values of the tidal charge and the brane tension based on the processes
going in the vicinity of neutron stars. We compare the strong field regime
restrictions with those given in the weak-field limit of solar system
experiments.Comment: 26 pages, 6 figure
Investigation of magneto-structural phase transition in FeRh by reflectivity and transmittance measurements in visible and near-infrared spectral region
Magneto-structural phase transition in FeRh epitaxial layers was studied optically. It is shown that the transition between the low-temperature antiferromagnetic phase and the high-temperature ferromagnetic phase is accompanied by a rather large change of the optical response in the visible and near-infrared spectral ranges. This change is consistent with ab initio calculations of reflectivity and transmittance. Phase transition temperatures in a series of FeRh films with thicknesses ranging from 6 to 100 nm is measured thereby demonstrating the utility of the method to quickly characterise samples. Spatially resolved imaging of their magnetic properties with a micrometer resolution shows that the phase transition occurs at different temperatures in different parts of the sample
Anomalous Magnetoresistance by Breaking Ice Rule in Bi2Ir2O7/Dy2Ti2O7 Heterostructure
While geometrically frustrated quantum magnets are known for a variety of
exotic spin states that are of great interests of understanding emergent
phenomena as well as enabling revolutionary quantum technologies, most of them
are necessarily good insulators which are difficult to be integrated with
modern electrical circuit that relies on moving charge carriers. The grand
challenge of converting fluctuations and excitations of frustrated moments into
electronic responses is finding ways to introduce charge carriers that interact
with the localized spins without destroying the spin states. Here, we show
that, by designing a Bi2Ir2O7/Dy2Ti2O7 heterostructure, the breaking of the
spin ice rule in insulating Dy2Ti2O7 can lead to a charge response in the
Bi2Ir2O7 conducting layer that can be detected as anomalous magnetoresistance.
These results demonstrate a novel and feasible interfacial approach for
electronically probing exotic spin states in insulating magnets, laying out a
blueprint for the metallization of frustrated quantum magnets
Co-encapsulation of human serum albumin and superparamagnetic iron oxide in PLGA nanoparticles: Part I. Effect of process variables on the mean size
PLGA (poly d,l-lactic-co-glycolic acid) nanoparticles (NPs) encapsulating magnetite nanoparticles (MNPs) along with a model drug human serum albumin (HSA) were prepared by double emulsion solvent evaporation method. This Part I will focus on size and size distribution of prepared NPs, whereas encapsulation efficiency will be discussed in Part II. It was found that mean hydrodynamic particle size was influenced by five important process variables. To explore their effects, a five-factorial, three-level experimental design and statistical analysis were carried out using STATISTICA® software. Effect of process variables on the mean size of nanoparticles was investigated and finally conditions to minimize size of NPs were proposed. GAMS™/MINOS software was used for optimization. The mean hydrodynamic size of nanoparticles ranged from 115 to 329 nm depending on the process conditions. Smallest possible mean particle size can be achieved by using low polymer concentration and high dispersion energy (enough sonication time) along with small aqueous/organic volume ratio
Novel Colicin F-Y of Yersinia frederiksenii Inhibits Pathogenic Yersinia Strains via YiuR-Mediated Reception, TonB Import, and Cell Membrane Pore Formation
A novel colicin type, designated colicin F-Y, was found to be encoded and produced by the strain Yersinia frederiksenii Y27601. Colicin F-Y was active against both pathogenic and nonpathogenic strains of the genus Yersinia. Plasmid YF27601 (5,574 bp) of Y. frederiksenii Y27601 was completely sequenced. The colicin F-Y activity gene (cfyA) and the colicin F-Y immunity gene (cfyI) were identified. The deduced amino acid sequence of colicin F-Y was very similar in its C-terminal pore-forming domain to colicin Ib (69% identity in the last 178 amino acid residues), indicating pore forming as its lethal mode of action. Transposon mutagenesis of the colicin F-Y-susceptible strain Yersinia kristensenii Y276 revealed the yiuR gene (ykris001_4440), which encodes the YiuR outer membrane protein with unknown function, as the colicin F-Y receptor molecule. Introduction of the yiuR gene into the colicin F-Y-resistant strain Y. kristensenii Y104 restored its susceptibility to colicin F-Y. In contrast, the colicin F-Y-resistant strain Escherichia coli TOP10F' acquired susceptibility to colicin F-Y only when both the yiuR and tonB genes from Y. kristensenii Y276 were introduced. Similarities between colicins F-Y and Ib, similarities between the Cir and YiuR receptors, and the detected partial cross-immunity of colicin F-Y and colicin Ib producers suggest a common evolutionary origin of the colicin F-Y-YiuR and colicin Ib-Cir systems
TbUTP10, a protein involved in early stages of pre-18S rRNA processing in <i>Trypanosoma brucei</i>
Foundations of Black Hole Accretion Disk Theory
This review covers the main aspects of black hole accretion disk theory. We
begin with the view that one of the main goals of the theory is to better
understand the nature of black holes themselves. In this light we discuss how
accretion disks might reveal some of the unique signatures of strong gravity:
the event horizon, the innermost stable circular orbit, and the ergosphere. We
then review, from a first-principles perspective, the physical processes at
play in accretion disks. This leads us to the four primary accretion disk
models that we review: Polish doughnuts (thick disks), Shakura-Sunyaev (thin)
disks, slim disks, and advection-dominated accretion flows (ADAFs). After
presenting the models we discuss issues of stability, oscillations, and jets.
Following our review of the analytic work, we take a parallel approach in
reviewing numerical studies of black hole accretion disks. We finish with a few
select applications that highlight particular astrophysical applications:
measurements of black hole mass and spin, black hole vs. neutron star accretion
disks, black hole accretion disk spectral states, and quasi-periodic
oscillations (QPOs).Comment: 91 pages, 23 figures, final published version available at
http://www.livingreviews.org/lrr-2013-
Unambiguous Formalism for Higher-Order Lagrangian Field Theories
The aim of this paper is to propose an unambiguous intrinsic formalism for
higher-order field theories which avoids the arbitrariness in the
generalization of the conventional description of field theories, which implies
the existence of different Cartan forms and Legendre transformations. We
propose a differential-geometric setting for the dynamics of a higher-order
field theory, based on the Skinner and Rusk formalism for mechanics. This
approach incorporates aspects of both, the Lagrangian and the Hamiltonian
description, since the field equations are formulated using the Lagrangian on a
higher-order jet bundle and the canonical multisymplectic form on its dual. As
both of these objects are uniquely defined, the Skinner-Rusk approach has the
advantage that it does not suffer from the arbitrariness in conventional
descriptions. The result is that we obtain a unique and global intrinsic
version of the Euler-Lagrange equations for higher-order field theories.
Several examples illustrate our construction.Comment: 21 pages; 4 diagrams; (this version) corrected typos; moved
paragraphs; publishe
Adaptive Honeypot Engagement through Reinforcement Learning of Semi-Markov Decision Processes
A honeynet is a promising active cyber defense mechanism. It reveals the
fundamental Indicators of Compromise (IoCs) by luring attackers to conduct
adversarial behaviors in a controlled and monitored environment. The active
interaction at the honeynet brings a high reward but also introduces high
implementation costs and risks of adversarial honeynet exploitation. In this
work, we apply infinite-horizon Semi-Markov Decision Process (SMDP) to
characterize a stochastic transition and sojourn time of attackers in the
honeynet and quantify the reward-risk trade-off. In particular, we design
adaptive long-term engagement policies shown to be risk-averse, cost-effective,
and time-efficient. Numerical results have demonstrated that our adaptive
engagement policies can quickly attract attackers to the target honeypot and
engage them for a sufficiently long period to obtain worthy threat information.
Meanwhile, the penetration probability is kept at a low level. The results show
that the expected utility is robust against attackers of a large range of
persistence and intelligence. Finally, we apply reinforcement learning to the
SMDP to solve the curse of modeling. Under a prudent choice of the learning
rate and exploration policy, we achieve a quick and robust convergence of the
optimal policy and value.Comment: The presentation can be found at https://youtu.be/GPKT3uJtXqk. arXiv
admin note: text overlap with arXiv:1907.0139
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