546 research outputs found
Effect of adult thymectomy on tumour immunity in mice.
The effect of adult thymectomy in DBA/2J mice on the in vitro response to syngeneic tumour cells was investigated. Spleen cells from adult mice which had been thymectomized 8 weeks previously demonstrated a severely impaired primary cytotoxic response to P815 tumour cells, whereas their cytotoxic responses to allogeneic cells (C57BL/6) and to non-H-2 antigens (BALB/c), and their ability to form a primary antibody response to sheep red blood cells was unimpaired. Suppressor T cells, specific for P815 cells, appeared early in the thymuses of animals inoculated with P815 cells (between 4 and 8 days after tumour-cell injection). No differences in tumour growth between animals thymectomized as adults and sham-operated controls were observed, and thymectomized tumour-bearing animals had levels of specific suppressor cells in their lymph nodes equivalent to the levels found in untreated controls. Severely thymocyte-deprived animals which had been thymectomized, irradiated and reconstituted with either marrow or spleen cells 8 weeks before tumour implantation succumbed more rapidly to metastatic tumour than did control animals
Biodiversity of living, non marine, thrombolites of Lake Clifton, Western Australia
<p>Lake Clifton in Western Australia is recognized as a critically endangered ecosystem and the only thrombolite reef in the southern hemisphere. There have been concerns that increases in salinity and nutrient run-off have significantly impacted upon the thrombolite microbial community. Here we used cultivation-independent molecular approaches to characterize the microbial diversity of the thrombolites at Lake Clifton. The most dominant phyla currently represented are the Proteobacteria with significant populations of Bacteroidetes and Firmicutes. Cyanobacteria, previously invoked as the main drivers of thrombolite growth, represent only a small fraction (âŒ1â3% relative abundance) of the microbial community. We report an increase in salinity and nitrogen levels at Lake Clifton that may be contributing to a change in dominant microbial populations. This heightens concerns about the long-term health of the Lake Clifton thrombolites; future work is needed to determine if phyla now dominating this system are capable of the required mineral precipitation for continued thrombolite growth.</p
Angular Dependence in Proton-Proton Correlation Functions in Central and Reactions
The angular dependence of proton-proton correlation functions is studied in
central and nuclear reactions at E=80
MeV/A. Measurements were performed with the HiRA detector complemented by the
4 Array at NSCL. A striking angular dependence in the laboratory frame is
found within p-p correlation functions for both systems that greatly exceeds
the measured and expected isospin dependent difference between the neutron-rich
and neutron-deficient systems. Sources measured at backward angles reflect the
participant zone of the reaction, while much larger sources observed at forward
angles reflect the expanding, fragmenting and evaporating projectile remnants.
The decrease of the size of the source with increasing momentum is observed at
backward angles while a weaker trend in the opposite direction is observed at
forward angles. The results are compared to the theoretical calculations using
the BUU transport model.Comment: 8 pages, 3 figures, submitted to PR
Correlations in intermediate-energy two-proton removal reactions
We report final-state-exclusive measurements of the light charged fragments
in coincidence with 26Ne residual nuclei following the direct two-proton
removal from a neutron-rich 28Mg secondary beam. A Dalitz-plot analysis and
comparisons with simulations show that a majority of the triple- coincidence
events with two protons display phase-space correlations consistent with the
(two-body) kinematics of a spatially-correlated pair-removal mechanism. The
fraction of such correlated events, 56(12) %, is consistent with the fraction
of the calculated cross section, 64 %, arising from spin S = 0 two-proton
configurations in the entrance-channel (shell-model) 28Mg ground state wave
function. This result promises access to an additional and more specific probe
of the spin and spatial correlations of valence nucleon pairs in exotic nuclei
produced as fast secondary beams.Comment: accepted for publication in Physical Review Letter
Investigations of three, four, and five-particle exit channels of levels in light nuclei created using a 9C beam
The interactions of a E/A=70-MeV 9C beam with a Be target was used to
populate levels in Be, B, and C isotopes which undergo decay into many-particle
exit channels. The decay products were detected in the HiRA array and the level
energies were identified from their invariant mass. Correlations between the
decay products were examined to deduce the nature of the decays, specifically
to what extent all the fragments were created in one prompt step or whether the
disintegration proceeded in a sequential fashion through long-lived
intermediate states. In the latter case, information on the spin of the level
was also obtained. Of particular interest is the 5-body decay of the 8C ground
state which was found to disintegrate in two steps of two-proton decay passing
through the 6Beg.s. intermediate state. The isobaric analog of 8Cg.s. in 8B was
also found to undergo two-proton decay to the isobaric analog of 6Beg.s. in
6Li. A 9.69-MeV state in 10C was found to undergo prompt 4-body decay to the
2p+2alpha exit channel. The two protons were found to have a strong
enhancementin the diproton region and the relative energies of all four p-alpha
pairs were consistent with the 5Lig.s. resonance
Spin alignment of excited projectiles due to target spin-flip interactions
The sequential breakup of E/A=65.5-MeVBe7 and E/A=36.6-MeVLi6 projectiles excited through inelastic interactions with Be9 target nuclei has been studied. For events where the target nucleus remained in its ground state, significant alignment of the excited projectile\u27s spin axis parallel or antiparallel to the beam direction was observed. This unusual spin alignment was found to be largely independent of the projectile\u27s scattering angle and it was deduced that the target nucleus has a significant probability of changing its spin orientation during the interaction. It is proposed that the unusual spin alignment is a consequence of the molecular structure of the Be9 nucleus
An Exploratory Study into the Factors Impeding Ethical Consumption
Although consumers are increasingly engaged with ethical factors when forming opinions about products and making purchase decisions, recent studies have highlighted significant differences between consumersâ intentions to consume ethically, and their actual purchase behaviour. This article contributes to an understanding of this âethical purchasing gapâ through a review of existing literature, and the inductive analysis of focus group discussions. A model is suggested which includes exogenous variables such as moral maturity and age which have been well covered in the literature, together with further impeding factors identified from the focus group discussions. For some consumers, inertia in purchasing behaviour was such that the decision-making process was devoid of ethical considerations. Several manifested their ethical views through post-purchase dissonance and retrospective feelings of guilt. Others displayed a reluctance to consume ethically due to personal constraints, a perceived negative impact on image or quality, or an outright negation of responsibility. Those who expressed a desire to consume ethically often seemed deterred by cynicism, which caused them to question the impact they, as an individual, could achieve. These findings enhance the understanding of ethical consumption decisions and provide a platform for future research in this area
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