1,104 research outputs found

    ELVES IV: The Satellite Stellar-to-Halo Mass Relation Beyond the Milky-Way

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    Quantifying the connection between galaxies and their host dark matter halos has been key for testing cosmological models on various scales. Below M109MM_\star \sim 10^9\,M_\odot, such studies have primarily relied on the satellite galaxy population orbiting the Milky Way. Here we present new constraints on the connection between satellite galaxies and their host dark matter subhalos using the largest sample of satellite galaxies in the Local Volume (D12MpcD \lesssim 12\,\mathrm{Mpc}) to date. We use 250250 confirmed and 7171 candidate dwarf satellites around 27 Milky Way (MW)-like hosts from the Exploration of Local VolumE Satellites (ELVES) Survey and use the semi-analytical SatGen model for predicting the population of dark matter subhalos expected in the same volume. Through a Bayesian model comparison of the observed and the forward-modeled satellite stellar mass functions (SSMF), we infer the satellite stellar-to-halo mass relation. We find that the observed SSMF is best reproduced when subhalos at the low mass end are populated by a relation of the form MMpeakαM_\star \propto M^\alpha_\mathrm{peak}, with a moderate slope of αconst=2.10±0.01\alpha_\mathrm{const}=2.10 \pm 0.01 and a low scatter, constant as a function of the peak halo mass, of σconst=0.060.05+0.07\sigma_\mathrm{const}=0.06^{+0.07}_{-0.05}. A model with a steeper slope (αgrow=2.39±0.06\alpha_\mathrm{grow}=2.39 \pm 0.06) and a scatter that grows with decreasing MpeakM_\mathrm{peak} is also consistent with the observed SSMF but is not required. Our new model for the satellite-subhalo connection, based on hundreds of Local Volume satellite galaxies, is in line with what was previously derived using only the Milky Way satellites.Comment: Accepted for publication in ApJ. Figure 8 shows the key result -- the Satellite Stellar to Halo Mass relation obtained in this work, in comparison to previous studie

    Diagnosis and outcome of oesophageal Crohn's disease

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    BACKGROUND AND AIMS: Crohn's disease (CD) can involve any part of the gastrointestinal tract. We aimed to characterize clinical, endoscopic, histologic features and treatment outcomes of CD patients with oesophageal involvement. METHODS: We collected cases through a retrospective multicentre European Crohn's and Colitis Organisation CONFER [COllaborative Network For Exceptionally Rare case reports] project. Clinical data were recorded in a standardized case report form. RESULTS: A total of 40 patients were reported [22 males, mean (±SD, range) age at oesophageal CD diagnosis: 25 (±13.3, 10-71) years and mean time of follow-up: 67 (±68.1, 3-240) months]. Oesophageal involvement was established at CD diagnosis in 26 patients (65%) and during follow-up in 14. CD was exclusively located in the oesophagus in 2 patients. Thirteen patients (32.2%) were asymptomatic at oesophageal disease diagnosis. Oesophageal strictures were present in 5 patients and fistulizing oesophageal disease in one. Eight patients exhibited granulomas on biopsies. Proton-pump inhibitors (PPIs) were administered in 37 patients (92.5%). Three patients underwent endoscopic dilation for symptomatic strictures and none oesophageal-related surgery. Diagnosis in pre-established CD resulted in treatment modifications in 9/14 patients. Clinical remission of oesophageal disease was seen in 33/40 patients (82.5%) after a mean time of 7 (±5.6, 1-18) months. Follow-up endoscopy was performed in 29/40 patients and 26/29 (89.7%) achieved mucosal healing. CONCLUSION: In this case series the endoscopic and histologic characteristics of isolated oesophageal CD were similar to those reported in other sites of involvement. Treatment was primarily conservative, with PPIs administered in the majority of patients and modifications in pre-existing IBD-related therapy occurring in two thirds of them. Clinical and endoscopic remission was achieved in more than 80% of the patients.info:eu-repo/semantics/publishedVersio

    Extinction Maps Toward The Milky Way Bulge: Two-Dimensional And Three-Dimensional Tests With APOGEE

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    Galactic interstellar extinction maps are powerful and necessary tools for Milky Way structure and stellar population analyses, particularly toward the heavily reddened bulge and in the midplane. However, due to the difficulty of obtaining reliable extinction measures and distances for a large number of stars that are independent of these maps, tests of their accuracy and systematics have been limited. Our goal is to assess a variety of photometric stellar extinction estimates, including both two-dimensional and three-dimensional extinction maps, using independent extinction measures based on a large spectroscopic sample of stars toward the Milky Way bulge. We employ stellar atmospheric parameters derived from high-resolution H-band Apache Point Observatory Galactic Evolution Experiment (APOGEE) spectra, combined with theoretical stellar isochrones, to calculate line-of-sight extinction and distances for a sample of more than 2400 giants toward the Milky Way bulge. We compare these extinction values to those predicted by individual near-IR and near+mid-IR stellar colors, two-dimensional bulge extinction maps, and three-dimensional extinction maps. The long baseline, near+mid-IR stellar colors are, on average, the most accurate predictors of the APOGEE extinction estimates, and the two-dimensional and three-dimensional extinction maps derived from different stellar populations along different sightlines show varying degrees of reliability. We present the results of all of the comparisons and discuss reasons for the observed discrepancies. We also demonstrate how the particular stellar atmospheric models adopted can have a strong impact on this type of analysis, and discuss related caveats.NSF Astronomy & Astrophysics Postdoctoral Fellowship AST-1203017Physics Frontier Center/Joint Institute for Nuclear Astrophysics (JINA) PHY 08-22648U.S. National Science FoundationAlfred P. Sloan FoundationParticipating InstitutionsU.S. Department of Energy Office of Science ANR-12-BS05-0015-01Astronom

    The First Ultra-cool Brown Dwarf Discovered by the Wide-field Infrared Survey Explorer

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    We report the discovery of the first new ultra-cool brown dwarf (BDs) found with the Wide-field Infrared Survey Explorer (WISE). The object’s preliminary designation is WISEPC J045853.90+643451.9. Follow-up spectroscopy with the LUCIFER instrument on the Large Binocular Telescope indicates that it is a very late-type T dwarf with a spectral type approximately equal to T9. Fits to an IRTF/SpeX 0.8–2.5 μm spectrum to the model atmospheres of Marley and Saumon indicate an effective temperature of approximately 600 K as well as the presence of vertical mixing in its atmosphere. The new BD is easily detected by WISE, with a signal-to-noise ratio of ~36 at 4.6 μm. Current estimates place it at a distance of 6–10 pc. This object represents the first in what will likely be hundreds of nearby BDs found by WISE that will be suitable for follow-up observations, including those with the James Webb Space Telescope. One of the two primary scientific goals of the WISE mission is to find the coolest, closest stars to our Sun; the discovery of this new BD proves that WISE is capable of fulfilling this objective

    Resting and reactive frontal brain electrical activity (EEG) among a non-clinical sample of socially anxious adults: does concurrent depressive mood matter?

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    A number of studies have noted that the pattern of resting frontal brain electrical activity (EEG) is related to individual differences in affective style in healthy infants, children, and adults and some clinical populations when symptoms are reduced or in remission. We measured self-reported trait shyness and sociability, concurrent depressive mood, and frontal brain electrical activity (EEG) at rest and in anticipation of a speech task in a non-clinical sample of healthy young adults selected for high and low social anxiety. Although the patterns of resting and reactive frontal EEG asymmetry did not distinguish among individual differences in social anxiety, the pattern of resting frontal EEG asymmetry was related to trait shyness after controlling for concurrent depressive mood. Individuals who reported a higher degree of shyness were likely to exhibit greater relative right frontal EEG activity at rest. However, trait shyness was not related to frontal EEG asymmetry measured during the speech-preparation task, even after controlling for concurrent depressive mood. These findings replicate and extend prior work on resting frontal EEG asymmetry and individual differences in affective style in adults. Findings also highlight the importance of considering concurrent emotional states of participants when examining psychophysiological correlates of personality

    The UT 7/8 February 2013 Sila-Nunam Mutual Event and Future Predictions

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    A superior mutual event of the Kuiper Belt binary system (79360) Sila-Nunam was observed over 15.47 h on UT 7/8 February 2013 by a coordinated effort at four different telescope facilities; it started approximately 1.5 h earlier than anticipated, the duration was approximately 9.5 h (about 10% longer than predicted), and was slightly less deep than predicted. It is the first full event observed for a comparably sized binary Kuiper Belt object. We provide predictions for future events refined by this and other partial mutual event observations obtained since the mutual event season began

    Relationships between Endogenous Plasma Biomarkers of Constitutive Cytochrome P450 3A Activity and Single-Time-Point Oral Midazolam Microdose Phenotype in Healthy Subjects

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    Due to high basal interindividual variation in cytochrome P450 3A (CYP3A) activity and susceptibility to drug interactions, there has been interest in the application of efficient probe drug phenotyping strategies, as well as endogenous biomarkers for assessment of in vivo CYP3A activity. The biomarkers 4β-hydroxycholesterol (4βHC) and 6β-hydroxycortisol (6βHCL) are sensitive to CYP3A induction and inhibition. However, their utility for the assessment of constitutive CYP3A activity remains uncertain. We investigated whether endogenous plasma biomarkers (4βHC and 6βHCL) are associated with basal CYP3A metabolic activity in healthy subjects assessed by a convenient single-time-point oral midazolam (MDZ) phenotyping strategy. Plasma 4βHC and 6βHCL metabolic ratios (MRs) were analysed in 51 healthy adult participants. CYP3A activity was determined after administration of an oral MDZ microdose (100 μg). Simple linear and multiple linear regression analyses were performed to assess relationships between MDZ oral clearance, biomarkers and subject covariates. Among study subjects, basal MDZ oral clearance, 4βHC and 6βHCL MRs ranged 6.5-, 10- and 13-fold, respectively. Participant age and alcohol consumption were negatively associated with MDZ oral clearance (p = 0.03 and p = 0.045, respectively), while weight and female sex were associated with lower plasma 4βHC MR (p = 0.0003 and p = 0.032, respectively). Neither 4βHC nor 6βHCL MRs were associated with MDZ oral clearance. Plasma 4βHC and 6βHCL MRs do not relate to MDZ single-time-point metabolic phenotype in the assessment of constitutive CYP3A activity among healthy individuals

    Boxy/peanut/X bulges, barlenses and the thick part of galactic bars: What are they and how did they form?

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    Bars have a complex three-dimensional shape. In particular their inner part is vertically much thicker than the parts further out. Viewed edge-on, the thick part of the bar is what is commonly known as a boxy-, peanut- or X- bulge and viewed face-on it is referred to as a barlens. These components are due to disc and bar instabilities and are composed of disc material. I review here their formation, evolution and dynamics, using simulations, orbital structure theory and comparisons to observations.Comment: 21 pages, 7 figures, invited review to appear in "Galactic Bulges", E. Laurikainen, R. Peletier, D. Gadotti, (eds.), Springe
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