Intentions to Return of Irregular Migrants: Illegality as a Cause of Skill Waste

In this paper we show that highly skilled illegal migrants may be more likely to return home than migrants with low or no skills when illegality causes skill waste, i.e. reduced ability of making use of individual capabilities both in the labor and the financial markets. This result is in contrast with common wisdom on return migration, according to which low-skill individuals are more likely to go back home rather than high-skill migrants. The simple theoretical life-cycle framework that shows the former result is tested on a sample of illegal migrants crossing Italian borders in 2003. The estimation results confirm that highly skilled illegal migrants are more willing to return home.Illegal migration, labor skills, skill waste.

The Planck-ATCA Co-eval Observations (PACO) project: the bright sample

The Planck-ATCA Co-eval Observations (PACO) have provided flux density measurements of well defined samples of AT20G radio sources at frequencies below and overlapping with Planck frequency bands, almost simultaneously with Planck observations. We have observed with the Australia Telescope Compact Array (ATCA) a total of 482 sources in the frequency range between 4.5 and 40 GHz in the period between July 2009 and August 2010. Several sources were observed more than once. In this paper we present the aims of the project, the selection criteria, and the observation and data reduction procedures. We also discuss the data in total intensity for a complete sample of 189 sources with S(20 GHz)>500 mJy, Galactic latitude |b|>5deg, and declination <-30deg, and some statistical analysis of the spectral behaviour and variability of this sample, referred to as the "bright PACO sample". Finally we discuss how these data could be used to transfer absolute calibrations to ground based telescopes using the CMB dipole calibrated flux densities measured by the Planck satellite, and we provide some test fluxes on bright calibrators.Comment: 15 pages, 11 figure. Accepted for publication on MNRAS. Catalogue availabl

Observing Grasping Actions Directed to Emotion-Laden Objects: Effects upon Corticospinal Excitability

The motor system is recruited whenever one executes an action as well as when one observes the same action being executed by others. Although it is well established that emotion modulates the motor system, the effect of observing other individuals acting in an emotional context is particularly elusive. The main aim of this study was to investigate the effect induced by the observation of grasping directed to emotion-laden objects upon corticospinal excitability (CSE). Participants classified video-clips depicting the right-hand of an actor grasping emotion-laden objects. Twenty video-clips differing in terms of valence but balanced in arousal level were selected. Motor evoked potentials (MEPs) were then recorded from the first dorsal interosseous using transcranial magnetic stimulation (TMS) while the participants observed the selected emotional video-clips. During the video-clip presentation, TMS pulses were randomly applied at one of two different time points of grasping: (1) maximum grip aperture, and (2) object contact time. CSE was higher during the observation of grasping directed to unpleasant objects compared to pleasant ones. These results indicate that when someone observes an action of grasping directed to emotion-laden objects, the effect of the object valence promotes a specific modulation over the motor system.Fil: Nogueira Campos, Anaelli A.. Universidade Federal de Juiz de Fora; BrasilFil: Saunier, Ghislain. Universidade Federal do Pará; BrasilFil: Della Maggiore, Valeria Monica. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Fisiología y Biofísica Bernardo Houssay. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Fisiología y Biofísica Bernardo Houssay; ArgentinaFil: De Oliveira, Laura A. S.. Centro Universitário Augusto Motta; BrasilFil: Rodrigues, Erika C.. Centro Universitário Augusto Motta; BrasilFil: Vargas, Claudia D.. Universidade Federal do Rio de Janeiro; Brasi

Like grandparents, like parents: Empirical evidence and psychoanalytic thinking on the transmission of parenting styles

The authors discuss the issue of intergenerational transmission of parenting from an empirical and psychoanalytic perspective. After presenting a framework to explain their conception of parenting, they describe intergenerational transmission of parenting as a key to interpreting and eventually changing parenting behaviors. Then they present (1) the empirical approach aimed at determining if there is actually a stability across generations that contributes to harsh parenting and eventually maltreatment and (2) the psyphoanalytic thinking that seeks to explain the continuity in terms of representations and clinical phenomena. The authors also discuss the relationship between the attachment and the caregiving systems and hypothesize a common base for the two systems in childhood experience. Finally, they propose the psychoanalytic perspective as a fruitful theoretical framework to integrate the evidence for the neurophysiological mediators and moderators of intergenerational transmission. Psychoanalytically informed research can provide clinically relevant insights and hypotheses to be tested

Preferential expression of the transcription coactivator HTIF1alpha gene in acute myeloid leukemia and MDS-related AML

HTIF1α, a transcription coactivator which is able to mediate RARα activity and functionally interact with PML, is encoded by a gene on chromosome 7q32–34, which is a critical region in acute myeloid leukemias (AML). With the assumption that this gene may be related to AML, we investigated the HTIF1α DNA structure and RNA expression in leukemic cells from 36 M1–M5 AML patients (28 ‘de novo’ and eight ‘secondary’ to myelodysplastic syndrome (MDS)). Abnormal HTIF1α DNA fragments were never found, whereas loss of HTIF1α DNA was observed in the patients with chromosome 7q32 deletion and translocation, and in one case without detectable chromosome 7 abnormality. HTIF1α RNA was found in acute myelocytic leukemic blasts, and was almost undetectable in normal mononuclear cells. The expression varied among the patients: higher in M1 to M3 subtypes, with the highest values in M1; low levels were constantly observed in M4 and M5 AML. In addition, HTIF1α was significantly overexpressed in MDS-related AML (MDR-AML), but not in MDS. We also found that HTIF1α expression was high in myeloid cell lines. In myeloblastic HL60 and promyelocytic NB4 cells, induced to differentiate along the monocytic–macrophage pathway by TPA or vitamin D3, HTIF1α expression decreased, whereas it was maintained at high levels on induction to granulocytic differentiation by RA or DMSO. In K562 cells, HTIF1α RNA levels did not change after hemin-induced erythroid differentiation. These results suggest that HTIF1α could play a role in myeloid differentiation, being distinctly regulated in hematopoietic lineages

Complete Genome Sequence of Pelosinus fermentans JBW45, a Member of a Remarkably Competitive Group of Negativicutes in the Firmicutes Phylum.

The genome of Pelosinus fermentans JBW45, isolated from a chromium-contaminated site in Hanford, Washington, USA, has been completed with PacBio sequencing. Nine copies of the rRNA gene operon and multiple transposase genes with identical sequences resulted in breaks in the original draft genome and may suggest genomic instability of JBW45

Evaluation of the masonry and timber structures of San Francisco Church in Santiago de Cuba through nondestructive diagnostic methods

Recently, due to a renewed interest in the religious architectural heritage of the Caribbean island of Cuba, some important interventions for the restoration and reinforcement of the colonial churches of the island were carried out. The authors, collaborating with the Archdiocese of Santiago de Cuba in a project concerning the protection of Cuban churches, applied some nondestructive and noninvasive destructive tests for an in-depth study of the main characteristics of those structures. The diagnostic method, developed mainly for the historical buildings or monuments of Europe and North America, was used to study some peculiarities of the building construction traditions of this area. The proposed techniques revealed the existence of several original solutions, for example, defenses for seismic mitigation, developed to resist the earthquakes that frequently affect the area

Three classes of ligands each bind to distinct sites on the orphan G protein-coupled receptor GPR84

Medium chain fatty acids can activate the pro-inflammatory receptor GPR84 but so also can molecules related to 3,3′-diindolylmethane. 3,3′-Diindolylmethane and decanoic acid acted as strong positive allosteric modulators of the function of each other and analysis showed the affinity of 3,3′-diindolylmethane to be at least 100 fold higher. Methyl decanoate was not an agonist at GPR84. This implies a key role in binding for the carboxylic acid of the fatty acid. Via homology modelling we predicted and confirmed an integral role of arginine172, located in the 2nd extracellular loop, in the action of decanoic acid but not of 3,3′-diindolylmethane. Exemplars from a patented series of GPR84 antagonists were able to block agonist actions of both decanoic acid and 3,3′-diindolylmethane at GPR84. However, although a radiolabelled form of a related antagonist, [3H]G9543, was able to bind with high affinity to GPR84, this was not competed for by increasing concentrations of either decanoic acid or 3,3′-diindolylmethane and was not affected adversely by mutation of arginine172. These studies identify three separable ligand binding sites within GPR84 and suggest that if medium chain fatty acids are true endogenous regulators then co-binding with a positive allosteric modulator would greatly enhance their function in physiological settings

Causality estimates among brain cortical areas by Partial Directed Coherence: simulations and application to real data

The problem of the definition and evaluation of brain connectivity has become a central one in neuroscience during the latest years, as a way to understand the organization and interaction of cortical areas during the execution of cognitive or motor tasks. Among various methods established during the years, the Partial Directed Coherence (PDC) is a frequency-domain approach to this problem, based on a multivariate autoregressive modeling of time series and on the concept of Granger causality. In this paper we propose the use of the PDC method on cortical signals estimated from high resolution EEG recordings, a non invasive method which exhibits a higher spatial resolution than conventional cerebral electromagnetic measures. The principle contributions of this work are the results of a simulation study, testing the performances of PDC, and a statistical analysis (via the ANOVA, analysis of variance) of the influence of different levels of Signal to Noise Ratio and temporal length, as they have been systematically imposed on simulated signals. An application to high resolution EEG recordings during a foot movement is also presented