42 research outputs found
Study of in the vicinity of
Using 2917 of data accumulated at 3.773~,
44.5~ of data accumulated at 3.65~ and data accumulated
during a line-shape scan with the BESIII detector, the reaction
is studied considering a possible interference
between resonant and continuum amplitudes. The cross section of
,
, is found to have two
solutions, determined to be () pb with the phase angle
(0.11 pb at the 90% confidence level),
or ) pb with both of which
agree with a destructive interference. Using the obtained cross section of
, the cross section of , which is useful information for the future PANDA experiment, is
estimated to be either () nb ( nb at 90% C.L.) or
nb
Recent developments in protein–ligand affinity mass spectrometry
This review provides an overview of direct and indirect technologies to screen protein–ligand interactions with mass spectrometry. These technologies have as a key feature the selection or affinity purification of ligands in mixtures prior to detection. Specific fields of interest for these technologies are metabolic profiling of bioactive metabolites, natural extract screening, and the screening of libraries for bioactives, such as parallel synthesis libraries and small combichem libraries. The review addresses the principles of each of the methods discussed, with a focus on developments in recent years, and the applicability of the methods to lead generation and development in drug discovery
Pre-dimensioning of the Dynamic Properties of the Wind Turbine System Using Analytical Approach
Cytoprotection of human endothelial cells from menadione cytotoxicity by caffeic acid phenethyl ester: the role of heme oxygenase-1
Caffeic acid phenethyl ester (CAPE), derived from various plant sources, has been shown to ameliorate ischemia/reperfusion injury in vivo, and this has been attributed to its ability to reduce oxidative stress. Here we investigated the cytoprotection of CAPE against menadione-induced oxidative stress in human umbilical vein endothelial cells (HUVEC) to evaluate potential gene expression involvement. CAPE exhibited dose-dependent cytoprotection of HUVEC. A gene screen with microarrays was performed to identify the potential cytoprotective gene(s) induced by CAPE. Heme oxygenase-1 (HO-1) was highly upregulated by CAPE and this was confirmed with reverse transcriptase polymerase chain reaction (RT-PCR) and western blotting. Inhibition of HO-1 activity using the HO-1 inhibitor tin protoporphyrin IX (SnPPIX), resulted in loss of cytoprotection. Carbon monoxide, one of HO-1 catabolic products appeared to play a small role in CAPE protection. Caffeic acid, a potential metabolite of CAPE with similar free radical scavenging ability, however, didn\u27t show any cytoprotective effect nor induce HO-1. These findings suggest an important role of HO-1 induction in CAPE cytoprotection against oxidant stress, which may not relate to CAPE structural antioxidant activity nor to its traditional enzymatic activity in decomposing heme but to a yet to be determined activity
Spin transfer torque in the semiconductor/ferromagnetic structure in the presence of Rashba effect
Decentralized adaptive suboptimal LQ control in Microsoft Excel VBA
Suboptimal linear quadratic (LQ) control has been popular very much because of its very good results in several tasks of control. It allows us to implement it on many systems even on unstable systems which it stabilizes. Adaptation enlarges the area of the usage especially in the case when standard controllers with fixed parameters gives unsatisfactory results. In this paper, the main attention is dedicated to the usage of the modified instrumental variable technique as the identification part of the self-tuning controllers, and to the implementation in Microsoft Excel. So this approach was verified by simulation in Microsoft Excel Visual Basic for Applications (VBA) on two input two output (TITO) systems. © 2019, Springer International Publishing AG, part of Springer Nature