A rare case of an aldosterone secreting metastatic adrenocortical carcinoma and papillary thyroid carcinoma in a 31-year-old male

We report a rare synchronous presentation of adrenocortical carcinoma (ACC) and papillary thyroid carcinoma (PTC). A 31-year-old male first presented with a large left adrenal mass that was identified during the workup for refractory hypertension due to hyperaldosteronism. The mass was removed surgically with pathology showing ACC. The patient was then treated with adjuvant radiation therapy and mitotane chemotherapy. Four months post ACC resection, metastatic ACC to the right upper lung and PTC in the left lobe of the thyroid were found in surveillance imaging. He subsequently developed pulmonary, contralateral adrenal and brain metastases from his ACC. Li Fraumeni syndrome and Multiple Endocrine Neoplasia Type I (MEN I) were considered, but testing of both P53 and menin genes showed no mutation. We also performed a review of the literature and found three similar cases, however gene mutation analysis was not performed.

Representations of sport in the revolutionary socialist press in Britain, 1988–2012

This paper considers how sport presents a dualism to those on the far left of the political spectrum. A long-standing, passionate debate has existed on the contradictory role played by sport, polarised between those who reject it as a bourgeois capitalist plague and those who argue for its reclamation and reformation. A case study is offered of a political party that has consistently used revolutionary Marxism as the basis for its activity and how this party, the largest in Britain, addresses sport in its publications. The study draws on empirical data to illustrate this debate by reporting findings from three socialist publications. When sport did feature it was often in relation to high profile sporting events with a critical tone adopted and typically focused on issues of commodification, exploitation and alienation of athletes and supporters. However, readers’ letters, printed in the same publications, revealed how this interpretation was not universally accepted, thus illustrating the contradictory nature of sport for those on the far left

Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine

[This corrects the article DOI: 10.1186/s13054-016-1208-6.]

Appendix to RSC--Hanford report. Trip report, Hanford Works, March 30--April 14, 1948; see also GEH-14040, 14712

This trip was to provide an answer to these questions: Are Hanford meteorological instrumentation, methods, and records adequate? Do they conform to generally recognized practice? Are they effectively utilized? What is the percentage frequency of wind classified according to conditions normal, least favorable and most favorable for dilution? What is the habitability of the Wahluke Slope north and northeast of the Columbia River, considering stack gases, various stack heights, any pertinent meteorological features? What is the habitability if the only contaminating sources are the piles? In preparation for and in the event of a major catastrophe with attendant relief and evacuation operations, which additional observation should be taken: What weather data should be assembled from the general vicinity of Hanford: What sampling program should take place immediately after the event. To these may be added a question raised by Dr. Parker in connection with the high level of contamination at the ground in the vicinity of the separations. areas