A review of knowledge: inter-row hoeing & its associated agronomy in organic cereal & pulse crops

The aim of this project was to establish the “state of the art” for inter-row hoeing and its associated agronomic practices in organic cereal and pulse crops. To achieve this a detailed review of literature was undertaken. • To facilitate inter-row cultivation in cereal and pulse crops, some adjustment of row spacing may be required. For cereals, drilling crops in 25 cm rows can reduce yield compared with normal drilling practice, primarily due to greater intra-specific competition amongst the crop (i.e. competition between crop plants). • The yield penalty resulting from widely spaced crop rows can be minimised using a number of approaches, depending on the drill: 1. Reducing the seed rate in widely spaced crop rows can help to minimise excessive intra-specific competition. 2. Band sowing the crop in wide rows can also help to minimise intra-specific competition as the seed is distributed over a greater area. 3. Using a twin-row arrangement can completely overcome the yield penalty. • The recommended row spacing for peas (up to 20 cm) and beans (up to 35 cm) does not require any further adjustment for inter-row hoeing. • Recent developments in automated guidance of inter-row hoeing equipment mean that weeding operations can now be conducted a much higher speeds (10 km h-1). This has highlighted the limitations of some of the cultivators currently used (e.g. ‘A’ blades), as excessive soil throw can occur at this high speed. Rolling cultivators may prove to be the most suitable at high forward speeds. For manually guided hoes working at slower speeds (5 km h-1), ‘A’ and ‘L’ blades offer an effective low cost solution. • In terms of the timing of inter-row hoeing, it is suggested that weeding operations should be conducted at an early stage in the growing season, as the weeds that emerge with or shortly after the crop are the ones that pose the most significant threat for crop yield. Weeding on two occasions can provide better levels of weed control than weeding once, but weeding more frequently offered little additional benefit. Reductions of weed biomass of up to 99 % have been reported as a result of inter-row hoeing, although this has not always resulted in a positive crop yield response. This is probably due to crop damage resulting from inaccurate hoeing, a problem that can be overcome with automated guidance. • There is some evidence to suggest that mechanical weeding operations can mineralise soil bound nitrogen. • The impact of inter-row hoeing on ground nesting birds is uncertain. Early indications suggest that skylarks prefer to nest directly adjacent to or in the crop row rather than between rows. The information contained within this review should enable farmers to make best use of inter-row hoeing in their arable crops. There are a number of areas that require further research and development: • The interaction of seed rate and row spacing needs to be confirmed in organic systems. • Relatively little is known about the mechanisms of weed kill and the detailed interaction between the cultivator blade, the weed and the soil. This is particularly important with the new automated guidance equipment that allows weeding at high forward speeds. • The timing and frequency of inter-row hoeing has received very little attention. The optimum weed control timings are based on small-plot crop:weed competition studies and need to be verified under field scale management with inter-row hoeing equipment. • Finally, the impact of inter-row hoeing and widely spaced crop rows on ground-nesting birds has not been looked at directly, but is of importance. Please see the main report for a more detailed summary before the full text

Preserving Bibliographic Relationships in Mappings from FRBR to BIBFRAME 2.0

In the environment of the World Wide Web large volumes of library data have been pub-lished following different conceptual models. The navigation through these volumes and the data interlinking require the development of mappings between the conceptual models. Library conceptual models provide constructs for the representation of bibliographic families and the relationships between Works. A key requirement for successful map-pings between different conceptual models is to preserve such content relationships. This paper studies a set of cases (Work with single Expression, Work with multiple Expres-sions, translation, adaptation) to examine if and how bibliographic content relationships and families could be preserved in mappings from FRBR to BIBFRAME 2.0. Even though, relationships between Works of the same bibliographic family may be preserved, the progenitor Work is not always represented in BIBFRAME after mappings

The N-terminal intrinsically disordered domain of mgm101p is localized to the mitochondrial nucleoid.

The mitochondrial genome maintenance gene, MGM101, is essential for yeasts that depend on mitochondrial DNA replication. Previously, in Saccharomyces cerevisiae, it has been found that the carboxy-terminal two-thirds of Mgm101p has a functional core. Furthermore, there is a high level of amino acid sequence conservation in this region from widely diverse species. By contrast, the amino-terminal region, that is also essential for function, does not have recognizable conservation. Using a bioinformatic approach we find that the functional core from yeast and a corresponding region of Mgm101p from the coral Acropora millepora have an ordered structure, while the N-terminal domains of sequences from yeast and coral are predicted to be disordered. To examine whether ordered and disordered domains of Mgm101p have specific or general functions we made chimeric proteins from yeast and coral by swapping the two regions. We find, by an in vivo assay in S.cerevisiae, that the ordered domain of A.millepora can functionally replace the yeast core region but the disordered domain of the coral protein cannot substitute for its yeast counterpart. Mgm101p is found in the mitochondrial nucleoid along with enzymes and proteins involved in mtDNA replication. By attaching green fluorescent protein to the N-terminal disordered domain of yeast Mgm101p we find that GFP is still directed to the mitochondrial nucleoid where full-length Mgm101p-GFP is targeted

A novel isolator-based system promotes viability of human embryos during laboratory processing

In vitro fertilisation (IVF) and related technologies are arguably the most challenging of all cell culture applications. The starting material is a single cell from which one aims to produce an embryo capable of establishing a pregnancy eventually leading to a live birth. Laboratory processing during IVF treatment requires open manipulations of gametes and embryos, which typically involves exposure to ambient conditions. To reduce the risk of cellular stress, we have developed a totally enclosed system of interlinked isolator-based workstations designed to maintain oocytes and embryos in a physiological environment throughout the IVF process. Comparison of clinical and laboratory data before and after the introduction of the new system revealed that significantly more embryos developed to the blastocyst stage in the enclosed isolator-based system compared with conventional open-fronted laminar flow hoods. Moreover, blastocysts produced in the isolator-based system contained significantly more cells and their development was accelerated. Consistent with this, the introduction of the enclosed system was accompanied by a significant increase in the clinical pregnancy rate and in the proportion of embryos implanting following transfer to the uterus. The data indicate that protection from ambient conditions promotes improved development of human embryos. Importantly, we found that it was entirely feasible to conduct all IVF-related procedures in the isolator-based workstations

Does ultrasound screening for abdominal aortic aneurysm reduce mortality?

Screening reduces mortality in men, although it's unclear whether it has the same effect in women. Screening for aortic abdominal aneurysm (AAA) with ultrasound in men 65 to 79 years of age reduces AAA-specific mortality (number needed to screen [NNS] to prevent one death from AAA=769 men over 3 years). However, a trend toward reduced all-cause mortality doesn't reach significance, possibly because of the low incidence of AAA (strength of recommendation [SOR]: A, systematic review of 4 population-based randomized controlled trials [RCTs]). Evidence is inadequate to demonstrate benefits of screening in women

Neonatal Myocardial Infarction or Myocarditis?

We report a 29 week-gestation preterm infant who presented during his second week of life with cardiogenic shock. Clinical presentation and first diagnostics suggested myocardial infarction, but echocardiographic features during follow-up pointed to a diagnosis of enteroviral myocarditis. The child died of chronic heart failure at 9 months of age. Autopsy showed passed myocardial infarction. No signs for active myocarditis were found. We discuss the difficulties in differentiating between neonatal myocardial infarction and myocarditis. Recognizing enteroviral myocarditis as cause for cardiogenic shock is of importance because of the therapeutic options

Composite Outcome Measures for Psoriatic Arthritis:OMERACT and 3 and 4 Visual Analog Scale Progress in 2023

The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)-Outcome Measures in Rheumatology (OMERACT) psoriatic arthritis (PsA) working group provided updates at the GRAPPA 2023 annual meeting on its work to evaluate composite outcome measures for PsA. An ongoing systematic literature review is in progress to evaluate psychometric measurement properties using the OMERACT filter 2.2 for a list of candidate composite outcome measures, which include minimal disease activity (MDA), Disease Activity for Psoriatic Arthritis (DAPSA), American College of Rheumatology (ACR) response criteria, Psoriatic Arthritis Disease Activity Score (PASDAS), Composite Psoriatic Disease Activity Index (CPDAI), 3 visual analog scale (3VAS), and 4VAS. The performance of the 3VAS and 4VAS in clinical practice and a synthesis of new data were presented, including estimates for minimal clinically important differences and thresholds of meaning, discrimination and construct validity, and longitudinal construct validity. Numeric rating scale (NRS) versions of the VAS have also been tested. Performance characteristics and psychometric properties are similar to the ASSESS study, a UK multicenter study, indicating that the VAS scales may be feasible tools for routine clinical care with a preference for the 4VAS because of superior face validity and clinical utility.</p

Quick, accurate, smart: 3D computer vision technology helps assessing confined animals' behaviour

Mankind directly controls the environment and lifestyles of several domestic species for purposes ranging from production and research to conservation and companionship. These environments and lifestyles may not offer these animals the best quality of life. Behaviour is a direct reflection of how the animal is coping with its environment. Behavioural indicators are thus among the preferred parameters to assess welfare. However, behavioural recording (usually from video) can be very time consuming and the accuracy and reliability of the output rely on the experience and background of the observers. The outburst of new video technology and computer image processing gives the basis for promising solutions. In this pilot study, we present a new prototype software able to automatically infer the behaviour of dogs housed in kennels from 3D visual data and through structured machine learning frameworks. Depth information acquired through 3D features, body part detection and training are the key elements that allow the machine to recognise postures, trajectories inside the kennel and patterns of movement that can be later labelled at convenience. The main innovation of the software is its ability to automatically cluster frequently observed temporal patterns of movement without any pre-set ethogram. Conversely, when common patterns are defined through training, a deviation from normal behaviour in time or between individuals could be assessed. The software accuracy in correctly detecting the dogs' behaviour was checked through a validation process. An automatic behaviour recognition system, independent from human subjectivity, could add scientific knowledge on animals' quality of life in confinement as well as saving time and resources. This 3D framework was designed to be invariant to the dog's shape and size and could be extended to farm, laboratory and zoo quadrupeds in artificial housing. The computer vision technique applied to this software is innovative in non-human animal behaviour science. Further improvements and validation are needed, and future applications and limitations are discussed.</p