431 research outputs found
Rural Flies in the Urban Environment?
Because metropolitan areas in the United States have been expanding at a dramatic rate, there has been direct competition between rural and urban interests for land. Also, market pressures often make it most profitable for meat producers to locate as close to urban centers as possible. A resultant growing interface between rural and urban centers, coupled with inadequate understanding of the people between the two centers, provides a potential for problems to develop. This book generally summarizes one area of contention - flies: few people tolerate flies in any setting anymore
Subcutaneous immunoglobulin replacement therapy in the treatment of patients with primary immunodeficiency disease
Antibody deficiency is the most frequently encountered primary immunodeficiency disease (PIDD) and patients who lack the ability to make functional immunoglobulin require life-long replacement therapy to prevent serious bacterial infections. Human serum immunoglobulin manufactured from pools of donated plasma can be administered intramuscularly, intravenously or subcutaneously. With the advent of well-tolerated preparations of intravenous immunoglobulin (IVIg) in the 1980s, the suboptimal painful intramuscular route of administration is no longer used. However, some patients continued to experience unacceptable adverse reactions to the intravenous preparations, and for others, vascular access remained problematic. Subcutaneously administered immunoglobulin (SCIg) provided an alternative delivery method to patients experiencing difficulties with IVIg. By 2006, immunoglobulin preparations designed exclusively for subcutaneous administration became available. They are therapeutically equivalent to intravenous preparations and offer patients the additional flexibility for the self-administration of their product at home. SCIg as replacement therapy for patients with primary antibody deficiencies is a safe and efficacious method to prevent serious bacterial infections, while maximizing patient satisfaction and improving quality of life
Resistance Status of House Flies (Diptera: Muscidae) from Southeastern Nebraska Beef Cattle Feedlots to Selected Insecticides
The status of resistance to three insecticides (permethrin, stirofos, and methoxychlor), relative to a laboratory-susceptible colony, was evaluated in Ăželd populations of house flies, Musca domestica L., collected from two beef cattle feedlots in southeastern Nebraska. Topical application and residual exposure to treated glass surfaces were suitable methods for determining the resistance status of house flies to permethrin, stirofos, or methoxychlor. However, in most cases, residual exposure was more sensitive in resistance detection (i.e., higher resistance ratios). The field populations tested were moderately resistant to permethrin (RR = 4.9-fold and RR = 7.3-fold, for topical application and residual exposure, respectively) and extremely resistant to stirofos and methoxychlor (not accurately quantifiable be cause of low mortality at the highest possible concentrations or doses). Probable explanations for the resistance status of these house fly populations and implications for global feedlot fly management are discussed
Mono- and double carbonylation of aryl iodides with amine nucleophiles in the presence of recyclable palladium catalysts immobilised on a supported dicationic ionic liquid phase
Silica modified with organic dicationic moieties proved to be an excellent support for palladium catalysts used in the aminocarbonylation of aryl iodides. By an appropriate choice of the reaction conditions, the same catalyst could be used for selective mono- or double carbonylations leading to amide and [small alpha]-ketoamide products, respectively. The best catalyst could be recycled for at least 10 consecutive runs with a loss of palladium below the detection limit. By the application of the new support, efficient catalyst recycling could be achieved under mild reaction conditions (under low pressure and in a short reaction time). Palladium-leaching data support a mechanism with dissolution-re-precipitation of the active palladium species
Dairy Farm Business Summary: Southeastern New York Region 1990
A.E. Ext. 91-17Dairy farmers throughout New York State have been participating in Cornell Cooperative Extension's farm business summary and analysis program since the early 1950's. Each participating farmer receives a comprehensive business summary and analysis of his or her farm business. The information in this report represents an average of the data submitted from farms in the Southeastern New York region
Analysis of radiation-induced cell death in head and neck squamous cell carcinoma and rat liver maintained in microfluidic devices
Objective The aim of this study was to investigate how head and neck squamous cell carcinoma (HNSCC) tissue biopsies maintained in a pseudo in vivo environment within a bespoke microfluidic device respond to radiation treatment. Study Design Feasibility study. Setting Tertiary referral center. Subjects and Methods Thirty-five patients with HNSCC were recruited, and liver tissue from 5 Wistar rats was obtained. A microfluidic device was used to maintain the tissue biopsy samples in a viable state. Rat liver was used to optimize the methodology. HNSCC was obtained from patients with T1-T3 laryngeal or oropharyngeal SCC; N1-N2 metastatic cervical lymph nodes were also obtained. Irradiation consisted of single doses of between 2 Gy and 40 Gy and a fractionated course of 5Ă—2 Gy. Cell death was assessed in the tissue effluent using the soluble markers lactate dehydrogenase (LDH) and cytochrome c and in the tissue by immunohistochemical detection of cleaved cytokeratin18 (M30 antibody). Results A significant surge in LDH release was demonstrated in the rat liver after a single dose of 20 Gy; in HNSCC, it was seen after 40 Gy compared with the control. There was no significant difference in cytochrome c release after 5 Gy or 10 Gy. M30 demonstrated a dose-dependent increase in apoptotic index for a given increase in single-dose radiotherapy. There was a significant increase in apoptotic index between 1Ă—2 Gy and 5Ă—2 Gy. Conclusion M30 is a superior method compared with soluble markers in detecting low-dose radiation-induced cell death. This microfluidic technique can be used to assess radiation-induced cell death in HNSCC and therefore has the potential to be used to predict radiation response
Hyperholomorpic connections on coherent sheaves and stability
Let be a hyperkaehler manifold, and a torsion-free and reflexive
coherent sheaf on . Assume that (outside of its singularities) admits a
connection with a curvature which is invariant under the standard SU(2)-action
on 2-forms. If the curvature is square-integrable, then is stable and its
singularities are hyperkaehler subvarieties in . Such sheaves (called
hyperholomorphic sheaves) are well understood. In the present paper, we study
sheaves admitting a connection with SU(2)-invariant curvature which is not
necessarily square-integrable. This situation arises often, for instance, when
one deals with higher direct images of holomorphic bundles. We show that such
sheaves are stable.Comment: 37 pages, version 11, reference updated, corrected many minor errors
and typos found by the refere
Observations of H-alpha, iron, and oxygen lines in B, Be, and shell stars
We have carried out a spectroscopic survey of several B, Be, and shell stars
in optical and near-infrared regions. Line profiles of the H-alpha line and of
selected Fe II and O I lines are presented.Comment: 23 pages, 45 figures; accepted in Astronomy & Astrophysic
On the cohomology of pseudoeffective line bundles
The goal of this survey is to present various results concerning the
cohomology of pseudoeffective line bundles on compact K{\"a}hler manifolds, and
related properties of their multiplier ideal sheaves. In case the curvature is
strictly positive, the prototype is the well known Nadel vanishing theorem,
which is itself a generalized analytic version of the fundamental
Kawamata-Viehweg vanishing theorem of algebraic geometry. We are interested
here in the case where the curvature is merely semipositive in the sense of
currents, and the base manifold is not necessarily projective. In this
situation, one can still obtain interesting information on cohomology, e.g. a
Hard Lefschetz theorem with pseudoeffective coefficients, in the form of a
surjectivity statement for the Lefschetz map. More recently, Junyan Cao, in his
PhD thesis defended in Grenoble, obtained a general K{\"a}hler vanishing
theorem that depends on the concept of numerical dimension of a given
pseudoeffective line bundle. The proof of these results depends in a crucial
way on a general approximation result for closed (1,1)-currents, based on the
use of Bergman kernels, and the related intersection theory of currents.
Another important ingredient is the recent proof by Guan and Zhou of the strong
openness conjecture. As an application, we discuss a structure theorem for
compact K{\"a}hler threefolds without nontrivial subvarieties, following a
joint work with F.Campana and M.Verbitsky. We hope that these notes will serve
as a useful guide to the more detailed and more technical papers in the
literature; in some cases, we provide here substantially simplified proofs and
unifying viewpoints.Comment: 39 pages. This survey is a written account of a lecture given at the
Abel Symposium, Trondheim, July 201
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