Paleomagnetism, magnetic anisotropy and U-Pb baddeleyite geochronology of the early Neoproterozoic Blekinge-Dalarna dolerite dykes, Sweden

Correction DOI: 10.1016/j.precamres.2018.10.013Peer reviewe

A three-group study, internet-based, face-to-face based and standard- management after acute whiplash associated disorders (WAD) – choosing the most efficient and cost-effective treatment: study protocol of a randomized controlled trial

<p>Abstract</p> <p>Background</p> <p>The management of Whiplash Associated Disorders is one of the most complicated challenges with high expenses for the health care system and society. There are still no general guidelines or scientific documentation to unequivocally support any single treatment for acute care following whiplash injury.</p> <p>The main purpose of this study is to try a new behavioural medicine intervention strategy at acute phase aimed to reduce the number of patients who have persistent problems after the whiplash injury. The goal is also to identify which of three different interventions that is most cost-effective for patients with Whiplash Associated Disorders. In this study we are controlling for two factors. First, the effect of behavioural medicine approach is compared with standard care. Second, the manner in which the behavioural medicine treatment is administered, Internet or face-to-face, is evaluated in it's effectiveness and cost-effectiveness.</p> <p>Methods/Design</p> <p>The study is a randomized, prospective, experimental three-group study with analyses of cost-effectiveness up to two-years follow-up. <it>Internet – based programme </it>and <it>face-to-face group treatment programme </it>are compared to <it>standard-treatment </it>only. Patient follow-ups take place three, six, twelve and 24 months, that is, short-term as well as long-term effects are evaluated. Patients will be enrolled via the emergency ward during the first week after the accident.</p> <p>Discussion</p> <p>This new self-help management will concentrate to those psychosocial factors that are shown to be predictive in long-term problems in Whiplash Associated Disorders, i.e. the importance of self-efficacy, fear of movement, and the significance of catastrophizing as a coping strategy for restoring and sustaining activities of daily life. Within the framework of this project, we will develop, broaden and evaluate current physical therapy treatment methods for acute Whiplash Associated Disorders. The project will contribute to the creation of a cost-effective behavioural medicine approach to management of acute Whiplash Associated Disorders. The results of this study will answer an important question; on what extent and how should these patients be treated at acute stage and how much does the best management cost.</p> <p>Trial registration number</p> <p>Current Controlled Trials ISRCTN61531337</p

КЕНГЕДИНСКИЙ МАФИЧЕСКИЙ ДАЙКОВЫЙ РОЙ И РАСШИРЕНИЕ КУОНАМСКОЙ КРУПНОЙ ИЗВЕРЖЕННОЙ ПРОВИНЦИИ (1500 МЛН ЛЕТ) СЕВЕРНОЙ СИБИРИ

Within the Anabar shield in the northern part of the Siberia, Late Precambrian mafic igneous units are widespread, which form dyke swarms of different ages of different trends. This paper presents new data on the composition, structure and U-Pb dating of the E-W trending Kengede dyke swarm. Three new U-Pb ID-TIMS baddeleyite ages (1496±7, 1494±3 and 1494±5 Ma) were obtained from three dykes, indicating that the Kengede swarm is part of the 1500 Ma Kuonamka large igneous province (LIP). The previously recognized Kuonamka Large Igneous Province (LIP) extends for 700 km from the Anabar shield to the Olenek uplift in the northern part of the Siberia and is potentially linked to coeval dykes and sills of the São Francisco craton and the Congo craton. The newly dated Kengede swarm is parallel to but offset by 50 km from the previously dated 1501±3 Ma Kuonamka swarm, and the identification of these two subparallel dyke subswarms of the Kuonamka LIP supports the earlier interpretation that mantle plume centre was located along the extrapolated trend of the dykes near the eastern or western margin of the Siberia. The paper examines features of sulfide Cu-Ni mineralization in dolerites of the Kengede and East Anabar dyke swarms and discusses potential Cu-Ni-sulfide mineralization linked to the Precambrian mafic dyke swarms of different ages in the north-east of the Siberia.В пределах Анабарского щита в северной части Сибирского кратона широко распространены позднедокембрийские базиты, которые формируют разновозрастные дайковые рои различного направления. В статье приводятся новые данные по составу, строению и U-Pb датировкам даек Кенгединского роя. Три новых возраста по бадделеиту (1496±7, 1494±3 и 1494±5 млн лет) из трех даек указывают на то, что Кенгединский рой даек является частью Куонамской крупной магматической провинции (КМП). Ранее выделенная Куонамская КМП простирается на 700 км от Анабарского щита до Оленекского поднятия в северной части Сибирской платформы и потенциально связана с синхронными дайками и силлами кратонов Сан-Франциско и Конго. Вновь датированный Кенгединский рой расположен параллельно в 50 км южнее от Куонамского роя даек (1501±3 млн лет), и идентификация этих двух самостоятельных субпараллельных дайковых роев Куонамской КМП подтверждает более раннюю интерпретацию того, что центр мантийного плюма располагался вдоль экстраполированного тренда даек вблизи восточной или западной окраины Сибирского кратона. В связи с этим в статье также рассматриваются особенности сульфидной Cu-Ni-минерализации в долеритах Кенгединского и Восточно- Анабарского дайковых роев и обсуждается потенциальное Cu-Ni-сульфидное оруденение, связанное с разновозрастными докембрийскими роями мафических даек на северо-востоке Сибирской платформы

Grey and white matter correlates of recent and remote autobiographical memory retrieval:Insights from the dementias

The capacity to remember self-referential past events relies on the integrity of a distributed neural network. Controversy exists, however, regarding the involvement of specific brain structures for the retrieval of recently experienced versus more distant events. Here, we explored how characteristic patterns of atrophy in neurodegenerative disorders differentially disrupt remote versus recent autobiographical memory. Eleven behavioural-variant frontotemporal dementia, 10 semantic dementia, 15 Alzheimer's disease patients and 14 healthy older Controls completed the Autobiographical Interview. All patient groups displayed significant remote memory impairments relative to Controls. Similarly, recent period retrieval was significantly compromised in behavioural-variant frontotemporal dementia and Alzheimer's disease, yet semantic dementia patients scored in line with Controls. Voxel-based morphometry and diffusion tensor imaging analyses, for all participants combined, were conducted to investigate grey and white matter correlates of remote and recent autobiographical memory retrieval. Neural correlates common to both recent and remote time periods were identified, including the hippocampus, medial prefrontal, and frontopolar cortices, and the forceps minor and left hippocampal portion of the cingulum bundle. Regions exclusively implicated in each time period were also identified. The integrity of the anterior temporal cortices was related to the retrieval of remote memories, whereas the posterior cingulate cortex emerged as a structure significantly associated with recent autobiographical memory retrieval. This study represents the first investigation of the grey and white matter correlates of remote and recent autobiographical memory retrieval in neurodegenerative disorders. Our findings demonstrate the importance of core brain structures, including the medial prefrontal cortex and hippocampus, irrespective of time period, and point towards the contribution of discrete regions in mediating successful retrieval of distant versus recently experienced events

World Society for Virology first international conference: Tackling global virus epidemics

This communication summarizes the presentations given at the 1st international conference of the World Society for Virology (WSV) held virtually during 16–18 June 2021, under the theme of tackling global viral epidemics. The purpose of this biennial meeting is to foster international collaborations and address important viral epidemics in different hosts. The first day included two sessions exclusively on SARS-CoV-2 and COVID-19. The other two days included one plenary and three parallel sessions each. Last not least, 16 sessions covered 140 on-demand submitted talks. In total, 270 scientists from 49 countries attended the meeting, including 40 invited keynote speakers.Peer reviewe

World Society for Virology first international conference: Tackling global virus epidemics.

Funder: Department of Health, Australian GovernmentThis communication summarizes the presentations given at the 1st international conference of the World Society for Virology (WSV) held virtually during 16-18 June 2021, under the theme of tackling global viral epidemics. The purpose of this biennial meeting is to foster international collaborations and address important viral epidemics in different hosts. The first day included two sessions exclusively on SARS-CoV-2 and COVID-19. The other two days included one plenary and three parallel sessions each. Last not least, 16 sessions covered 140 on-demand submitted talks. In total, 270 scientists from 49 countries attended the meeting, including 40 invited keynote speakers