Modeling the viscoplastic behavior of Inconel 718 at 1200 F

A large number of tests, including tensile, creep, fatigue, and creep-fatigue were performed to characterize the mechanical properties of Inconel 718 (a nickel based superalloy) at 1200 F, the operating temperature for turbine blades. In addition, a few attempts were made to model the behavior of Inconel 718 at 1200 F using viscoplastic theories. The Chaboche theory of viscoplasticity can model a wide variety of mechanical behavior, including monotonic, sustained, and cyclic responses of homogeneous, initially-isotropic, strain hardening (or softening) materials. It is shown how the Chaboche theory can be used to model the viscoplastic behavior of Inconel 718 at 1200 F. First, an algorithm was developed to systematically determine the material parameters of the Chaboche theory from uniaxial tensile, creep, and cyclic data. The algorithm is general and can be used in conjunction with similar high temperature materials. A sensitivity study was then performed and an optimal set of Chaboche's parameters were obtained. This study has also indicated the role of each parameter in modeling the response to different loading conditions

Modelling and characterization of cell collapse in aluminium foams during dynamic loading

Plate-impact experiments have been conducted to investigate the elastic–plastic behaviour of shock wave propagation and pore collapse mechanisms of closed-cell aluminium foams. FE modelling using a meso-scale approach has been carried out with the FE software ABAQUS/Explicit. A micro-computed tomography-based foam geometry has been developed and microstructural changes with time have been investigated to explore the effects of wave propagation. Special attention has been given to the pore collapse mechanism. The effect of velocity variations on deformation has been elucidated with three different impact conditions using the plate-impact method. Free surface velocity (ufs) was measured on the rear of the sample to understand the evolution of the compaction. At low impact velocities, the free-surface velocity increased gradually, whereas an abrupt rise of free-surface velocity was found at an impact velocity of 845 m/s with a copper flyer-plate which correlates with the appearance of shock. A good correlation was found between experimental results and FE predictions

Nonlinear Stress Fluctuation Dynamics of Sheared Disordered Wet Foam

Sheared wet foam, which stores elastic energy in bubble deformations, relaxes stress through bubble rearrangements. The intermittency of bubble rearrangements in foam leads to effectively stochastic drops in stress that are followed by periods of elastic increase. We investigate global characteristics of highly disordered foams over three decades of strain rate and almost two decades of system size. We characterize the behavior using a range of measures: average stress, distribution of stress drops, rate of stress drops, and a normalized fluctuation intensity. There is essentially no dependence on system size. As a function of strain rate, there is a change in behavior around shear rates of $0.07 {\rm s^{-1}}$.Comment: accepted to Physical Review

Seasonal influences on first-episode admission in affective and non-affective psychosis

Background: Since bipolar affective disorder has been recorded, clinicians treating patients with this disorder have noted the cyclic nature of episodes, particularly an increase in mania in the spring and summer months and depression during winter. Objective: The aim of this study was to investigate seasonality in symptom onset and service admissions over a period of 10 years in a group of patients (n= 359) with first-episode (FE) mania (n= 133), FE schizoaffective disorder (n= 49) and FE schizophrenia (n= 177). Method: Patients were recruited if they were between 15 and 28 years of age and if they resided in the geographical mental health service catchment area. The number of patients experiencing symptom onset and service admission over each month and season was recorded. Results: In terms of seasonality of time of service admission, the results indicate a high overall seasonality (particularly in men), which was observed in both the schizoaffective and the bipolar groups. In terms of seasonality of symptom onset, the results indicate that seasonality remains in the male bipolar group, but other groups have no seasonal trend. Conclusions: This provides further evidence that systems mediating the entrainment of biological rhythms to the environment may be more pronounced in BPAD than in schizoaffective disorder and schizophrenia. These results may help facilitate the preparedness of mental heath services for patients at different times of the yea

Strong Universality in Forced and Decaying Turbulence

The weak version of universality in turbulence refers to the independence of the scaling exponents of the $n$th order strcuture functions from the statistics of the forcing. The strong version includes universality of the coefficients of the structure functions in the isotropic sector, once normalized by the mean energy flux. We demonstrate that shell models of turbulence exhibit strong universality for both forced and decaying turbulence. The exponents {\em and} the normalized coefficients are time independent in decaying turbulence, forcing independent in forced turbulence, and equal for decaying and forced turbulence. We conjecture that this is also the case for Navier-Stokes turbulence.Comment: RevTex 4, 10 pages, 5 Figures (included), 1 Table; PRE, submitte

Engineering squeezed states in high-Q cavities

While it has been possible to build fields in high-Q cavities with a high degree of squeezing for some years, the engineering of arbitrary squeezed states in these cavities has only recently been addressed [Phys. Rev. A 68, 061801(R) (2003)]. The present work examines the question of how to squeeze any given cavity-field state and, particularly, how to generate the squeezed displaced number state and the squeezed macroscopic quantum superposition in a high-Q cavity

Propagation of squeezed radiation through amplifying or absorbing random media

We analyse how nonclassical features of squeezed radiation (in particular the sub-Poissonian noise) are degraded when it is transmitted through an amplifying or absorbing medium with randomly located scattering centra. Both the cases of direct photodetection and of homodyne detection are considered. Explicit results are obtained for the dependence of the Fano factor (the ratio of the noise power and the mean current) on the degree of squeezing of the incident state, on the length and the mean free path of the medium, the temperature, and on the absorption or amplification rate.Comment: 8 pages, 4 figure

Mucosal-Associated Invariant T Cells in the Human Gastric Mucosa and Blood: Role in Helicobacter pylori Infection

Mucosal-associated invariant T (MAIT) cells represent a class of antimicrobial innate-like T cells that have been characterized in human blood, liver, lungs, and intestine. Here, we investigated, for the first time, the presence of MAIT cells in the stomach of children, adults, and the elderly undergoing routine endoscopy and assessed their reactivity to Helicobacter pylori (H. pylori – Hp), a major gastric pathogen. We observed that MAIT cells are present in the lamina propria compartment of the stomach and display a similar memory phenotype to blood MAIT cells. We then demonstrated that gastric and blood MAIT cells are able to recognize H. pylori. We found that CD8(+) and CD4(−)CD8(−) (double negative) MAIT cell subsets respond to H. pylori-infected macrophages stimulation in a MR-1 restrictive manner by producing cytokines (IFN-γ, TNF-α, IL-17A) and exhibiting cytotoxic activity. Interestingly, we observed that blood MAIT cell frequency in Hp(+ve) individuals was significantly lower than in Hp(−ve) individuals. However, gastric MAIT cell frequency was not significantly different between Hp(+ve) and Hp(−ve) individuals, demonstrating a dichotomy between blood and gastric tissues. Further, we observed that the majority of gastric MAIT cells (>80%) expressed tissue-resident markers (CD69(+) CD103(+)), which were only marginally present on PBMC MAIT cells (<3%), suggesting that gastric MAIT cells are readily available to respond quickly to pathogens. These results contribute important new information to the understanding of MAIT cells function on peripheral and mucosal tissues and its possible implications in the host response to H. pylori

Autopsie d’une membrane d’osmose inverse usagée prélevée dans le Parc National du Banc d’Arguin (PNBA) en Mauritanie : cas d’étude de Teichitt

L’objectif de ce travail est d’étudier l’état de vieillissement d’une membrane d’osmose inverse (OI) usagée prélevée en Mauritanie sur une unité de dessalement installée par la coopération canarienne à Teichitt dans le parc national du banc d’Arguin et de lui appliquer une démarche d’autopsie. L’usure de la membrane est caractérisée par une augmentation significative de la perméabilité hydraulique (25 % d’augmentation) et une diminution de la rétention en sels (10 % à 30 % de diminution). Un modèle de transfert de matière de type diffusion-convection permet de montrer l’augmentation du caractère convectif du transfert, lorsque la pression transmembranaire augmente et en particulier au-delà de 15 bars. Ainsi, l’usure de la membrane d’OI induit son rapprochement vers un transfert de matière combiné de solubilisation-diffusion/convection, typique d’une opération de nanofiltration (NF). L’analyse topographique par AFM de la surface de la membrane usagée en comparaison de la membrane neuve laisse apparaître des « cavités » à plusieurs endroits de la surface usagée traduisant la dégradation physique de celle-ci. De plus, la rugosité de surface de la membrane usagée avec 74 nm est apparue supérieure à celle de la membrane neuve avec 54 nm, ce qui nous informe de la présence de matières colmatantes, dont la nature reste encore à déterminer. Par contre, l’étude de la dégradation chimique des membranes usagées et neuves par la détermination de leur point isoélectrique (PIE) à partir d’une mesure de potentiel d’écoulement transmembranaire ne montre pas de modifications significatives de ce paramètre (PIE = 2,5), preuve de la non-dégradation chimique interne de la membrane. Enfin, les résultats d’une étude statistique préliminaire sont présentés. Celle-ci consiste à évaluer l’hétérogénéité de l’usure en matière de perméabilité hydraulique et de rétention d’une solution de NaCl 0,1 M à 15 bars et 19 °C, pour six coupons différents pris sur les trois feuilles de membranes constituant le module d’osmose inverse usagé. Une tendance se dégage, elle montre en particulier que l’usure est hétérogène, non seulement au sein d’une même feuille de membrane, mais aussi au sein des différentes membranes constituant le module. En résumé, il est observé pour la première fois qu’une vieille membrane d’OI employée pendant deux années pour le dessalement d’eau de mer, dans les conditions d’utilisation sahariennes en Mauritanie (sans pré-traitements), acquiert une microporosité qui lui confère les propriétés d’une membrane de nanofiltration.Currently used reverse osmosis (RO) membranes from desalination units are burned at the end of their life as membranes for seawater desalination. In the future, a possible alternative would be to reuse the old RO membranes as nanofiltration (NF), ultrafiltration (UF) or microfiltration (MF) membranes, i.e. for wastewater treatments, but before reuse, the level of RO membrane degradation must be evaluated by autopsy studies.Our goal in the present study was to demonstrate for the first time that a used RO membrane could be used for nanofiltration. The used RO membrane was purchased from a desalination bench scale unit based in the town of Teichitt (in north-west Nouakchott, Mauritania). Membrane autopsy studies showed an increase in its hydraulic permeability (25%) and a concurrent decrease in its salt rejection behaviour (10% to 30%). We also studied the modification of mass transfer before and after ageing, and demonstrated the onset of a convective component in the mass transfer of salts and an increase in membrane hydraulic permeability. Furthermore, the determination of the isoelectric point (IEP) of the membrane, using streaming potential measurements across the membranes, showed no change in IEP, with a value of 2.5 ± 0.2 . A preliminary study, based on a statistical evaluation of membrane degradation from hydraulic permeability and salt rejection experiments, showed heterogeneous wear of the membrane (most important in the centre). Finally, we observed for the first time that after two years of use for desalination, a used RO membrane had acquired a microporosity that corresponded to the properties of a new NF membrane

Investment in Advanced Manufacturing Technology: A Study of Practice in Large UK Companies

This paper reports the results of a survey investigation into the investment decision making practices of large UK manufacturing companies, especially in relation to investments in advanced manufacturing technologies. A 24% response rate was received in a survey of the finance directors of 466 large UK manufacturing companies. Responses were classified into three groups ranging from non-users of AMT to sophisticated users and analysis revealed that more sophisticated users do emphasise certain intangible benefits in combination with measures relating to the traditional dimensions of return and risk