67 research outputs found
Improving Fixed-Point Implementation of QR Decomposition by Rounding-to-Nearest
QR decomposition is a key operation in many
current communication systems. This paper shows how to reduce
the area of a fixed-point QR decomposition implementation
based on Givens rotations by using a new number representation
system. This new representation allows performing round-tonearest
at the same cost of truncation. Consequently, the
rounding errors of the results are halved, which allows it to
reduce the word-length by one bit. This reduction positively
impacts on the area, delay and power consumption of the design.Ministry of Education and Science of Spain and Junta of AndalucĂa under contracts TIN2013-42253-P
and TIC-1692, respectively, and Universidad de Málaga. Campus de Excelencia Internacional AndalucĂa Tech
High-Throughput FPGA Implementation of QR Decomposition
Munoz, S.D.; Hormigo, J. "High-Throughput FPGA Implementation of QR Decomposition" IEEE Transactions on in Circuits and Systems II: Express Briefs,vol.62, no.9, pp.861-865, Sept. 2015 doi: 10.1109/TCSII.2015.2435753This brief presents a hardware design to achieve
high-throughput QR decomposition, using Givens Rotation Method. It utilizes a new two-dimensional systolic array architecture
with pipelined processing elements, which are based on the COordinate Rotation DIgital Computer (CORDIC) algorithm. CORDIC computes vector rotations through shifts and additions.
This approach allows a continuous computation of QR factorizations with simple hardware. A fixed-point FPGA architecture for 4 x 4 matrices has been optimized by balancing the number of CORDIC iterations with the final error. As a result, compared to other previous proposals for FPGA, our design achieves at least 50% more throughput, and much less resource utilization.Ministry of Education and Science of Spain and Junta of Andalucia under contracts TIN2013-42253-P and
P07-TIC-02630, respectively
Avanzando hacia un curriculum por competencias profesionales en IngenierĂa AgronĂłmica
Un rasgo esencial de las competencias es la relaciĂłn entre práctica-teorĂa, en la cual la práctica delimita la teorĂa acorde a condiciones y demandas de situaciones concretas en un contexto dado. En las Ciencias Agrarias hay consenso que el sustento de la formaciĂłn profesional está en la interdisciplinariedad, por tanto se plantea la necesidad de abordar el estudio de los agrosistemas desde equipos multidisciplinarios. El objetivo de este trabajo es evaluar la experiencia “Proyecto cursos correlativos por crĂ©dito12: IntegraciĂłn de conocimientos a partir de la articulaciĂłn teorĂa-práctica desde la FĂsica al manejo conservacionista del cultivo” – EdiciĂłn 2010 y 2011–. En la misma participaron alumnos que habĂan regularizado la asignatura MecanizaciĂłn AgrĂcola de la carrera IngenierĂa AgronĂłmica y docentes de las cátedras de FĂsica, TopografĂa, EdafologĂa, MecanizaciĂłn AgrĂcola, Manejo de Suelo y Riego y Cultivos Industriales; desarrollándose actividades de integraciĂłn entre las áreas curriculares de la carrera. Los resultados fueron analizados desde la percepciĂłn del alumno mediante encuestas y desde los docentes mediante el análisis de las mismas, la observaciĂłn participante, registros y la reflexiĂłn grupal; de lo cual surge que esta metodologĂa didáctica innovadora, permite avanzar hacia una formaciĂłn en competencias profesionales.Eje temático 1: Problemáticas y alternativas de mejora de la enseñanza
e - Los enfoques y modalidades de integraciĂłn curricularFacultad de Ciencias Agrarias y Forestale
Monitoring Radiographic Brain Tumor Progression
Determining radiographic progression in primary malignant brain tumors has posed a significant challenge to the neuroncology community. Glioblastoma multiforme (GBM, WHO Grade IV) through its inherent heterogeneous enhancement, growth patterns, and irregular nature has been difficult to assess for progression. Our ability to detect tumor progression radiographically remains inadequate. Despite the advanced imaging techniques, detecting tumor progression continues to be a clinical challenge. Here we review the different criteria used to detect tumor progression, and highlight the inherent challenges with detection of progression
YKL-40 tissue expression and plasma levels in patients with ovarian cancer
<p>Abstract</p> <p>Background</p> <p>YKL-40 (chitinase-3-like-1) is a member of "mammalian chitinase-like proteins". The protein is expressed in many types of cancer cells and the highest plasma YKL-40 levels have been found in patients with metastatic disease, short recurrence/progression-free intervals, and short overall survival. The aim of the study was to determine the expression of YKL-40 in tumor tissue and plasma in patients with borderline ovarian tumor or epithelial ovarian cancer (OC), and investigate prognostic value of this marker.</p> <p>Methods</p> <p>YKL-40 protein expression was determined by immunohistochemistry in tissue arrays from 181 borderline tumors and 473 OC. Plasma YKL-40 was determined by ELISA in preoperative samples from 19 patients with borderline tumor and 76 OC patients.</p> <p>Results</p> <p>YKL-40 protein expression was found in cancer cells, tumor associated macrophages, neutrophils and mast cells. The tumor cell expression was higher in OC than in borderline tumors (p = 0.001), and associated with FIGO stage (p < 0.0001) and histological subtype (p = 0.0009). Positive YKL-40 expression (≥ 5% staining) was not associated with reduced survival. Plasma YKL-40 was also higher in patients with OC than in patients with borderline tumors (p < 0.0001), and it was positively correlated to serum CA-125 (p < 0.0001) and FIGO stage (p = 0.0001). Univariate Cox analysis of plasma YKL-40 showed association with overall survival (p < 0.0001). Multivariate Cox analysis, including plasma YKL-40, serum CA125, FIGO stage, age and radicality after primary surgery as variables, showed that elevated plasma YKL-40 was associated with a shorter survival (HR = 2.13, 95% CI: 1.40–3.25, p = 0.0004).</p> <p>Conclusion</p> <p>YKL-40 in OC tissue and plasma are related to stage and histology, but only plasma YKL-40 is a prognostic biomarker in patients with OC.</p
Enabling and Enhancing Science Exploration Across the Solar System: Aerocapture Technology for SmallSat to Flagship Missions
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Designed Enzymatic Cascades
One of the major advantage of enzymes as catalyst is that many of them work in similar conditions of pH, temperature, etc. and thus can be combined in one-pot multi-step reactions pathways. The jointed action of a sequence of enzymes allows to build complex structures from simple elements; to make irreversible a reversible process or to shift the equilibrium reaction in a way that enantiomerically pure products can be obtained from racemic or prochiral substrates. In this chapter we want to highlight the developments of recent studies involving multi-enzyme cascade reactions for the synthesis of different classes of organic compounds.Peer reviewe
PHASE II TRIAL OF CONTINUOUS LOW-DOSE TEMOZOLOMIDE FOR PATIENTS WITH RECURRENT MALIGNANT GLIOMA
Expression of CD133+ in the brain of a mouse model with a lacZ reporter knock-in at the CD133 locus
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