2,938 research outputs found
Semantic annotation in ubiquitous healthcare skills-based learning environments
This paper describes initial work on developing a semantic annotation system for the augmentation of skills-based learning for Healthcare. Scenario driven skills-based learning takes place in an augmented hospital ward simulation involving a patient simulator known as SimMan. The semantic annotation software enables real-time annotations of these simulations for debriefing of the students, student self study and better analysis of the learning approaches of mentors. A description of the developed system is provided with initial findings and future directions for the work.<br/
Mitochondrial plasmids of the pCp family are spread worldwide in Cryphonectria parasitica populations
Vegetation outlines of two active rock glaciers with contrasting lithology
Rock glaciers are periglacial landforms consisting of coarse debris with interstitial ice or ice core, characterized by creeping due to ice deformation.
These landforms are drawing the attention of plant ecologist as harsh habitats and potential refugia in the global change context. Our aim was to
describe the vegetation outlines of two active rock glaciers of the Ortles-Cevedale Massif (Central Italian Alps) on different substrates (silicate and
carbonate) and compare them with the neighboring stable slopes and scree slopes. Two hypotheses were tested: 1) rock glaciers differ from the surrounding
landforms for the presence of cold-adapted plant communities; 2) rock glacier plant communities indicate similar microclimatic conditions
in spite of the contrasting lithology. Data were collected by phytosociological method performing 80 relev\ue9s of 25 m\ub2. Plant communities were
compared by a cluster analysis based on the presence/absence species matrix and species relative frequencies for each landform were calculated. The
cluster analysis separated first for all the two sites; afterwards, the landforms were differently discerned each other depending on the site. Despite
the remarkable floristic differences due to the substrate, the vegetation of both rock glaciers suggest a general adjustment to cold-moist microclimate
and long-lasting snow cover, differentiating more or less evidently from the adjacent scree slopes and enhancing the survival of nival entities at the
elevation of alpine grasslands
Synergistic effect of eltrombopag and deferasirox in aplastic anemia: a clinical case and review of the literature
Optimization of Esterase Production in Solid-State Fermentation of Agricultural Digestate
The continuous increase in biogas production poses the need for innovative applications for its by-products. Solid-state fermentation (SSF) has regained attention in the development of several products because of the possibility to use low-cost and easily available substrates, such as organic wastes. SSF represents a valuable process for agricultural digestate valorization in terms of enzyme production. In the present study, cellulase and esterase were produced by Trichoderma asperellum R on a digestate-based substrate in SSF, with esterase as the highest obtained activity. After assessing the effect of light on it, the esterase production in SSF was optimized using response surface methodology. The influence of substrate composition, temperature and humidity on the enzyme production was evaluated on two sets of data generated based on digestate concentration (50% and 70% w/w). The statistical analyses revealed that these parameters affected esterase production only when Trichoderma asperellum grew on substrate containing 50% w/w of digestate. The best esterase activity (264.6 mU/mg total protein) was achieved with the following optimized SSF parameters: 50% digestate, 50% fruits, 10% sawdust, 30 & DEG;C. The current finding of esterase production on digestate-based substrates makes the SSF method presented here a sustainable and completely circular technology
The influence of soil moisture on threshold runoff generation processes in an alpine headwater catchment
This study investigates the role of soil moisture on the threshold runoff response in a small headwater catchment in the Italian Alps that is characterised by steep hillslopes and a distinct riparian zone. This study focuses on: (i) the threshold soil moisture-runoff relationship and the influence of catchment topography on this relation; (ii) the temporal dynamics of soil moisture, streamflow and groundwater that characterize the catchment's response to rainfall during dry and wet periods; and (iii) the combined effect of antecedent wetness conditions and rainfall amount on hillslope and riparian runoff. Our results highlight the strong control exerted by soil moisture on runoff in this catchment: a sharp threshold exists in the relationship between soil water content and runoff coefficient, streamflow, and hillslope-averaged depth to water table. Low runoff ratios were likely related to the response of the riparian zone, which was almost always close to saturation. High runoff ratios occurred during wet antecedent conditions, when the soil moisture threshold was exceeded. In these cases, subsurface flow was activated on hillslopes, which became a major contributor to runoff. Antecedent wetness conditions also controlled the catchment's response time: during dry periods, streamflow reacted and peaked prior to hillslope soil moisture whereas during wet conditions the opposite occurred. This difference resulted in a hysteretic behaviour in the soil moisture-streamflow relationship. Finally, the influence of antecedent moisture conditions on runoff was also evident in the relation between cumulative rainfall and total stormflow. Small storms during dry conditions produced low stormflow amounts, likely mainly from overland flow from the near saturated riparian zone. Conversely, for rainfall events during wet conditions, higher stormflow values were observed and hillslopes must have contributed to streamflow
A multiwavelength numerical model in support of quantitative retrievals of aerosol properties from automated lidar ceilometers and test applications for AOT and PM10 estimation
Abstract. The use of automated lidar ceilometer (ALC) systems for the
aerosol vertically resolved characterization has increased in recent
years thanks to their low construction and operation costs and their
capability of providing continuous unattended measurements. At the same time
there is a need to convert the ALC signals into usable geophysical
quantities. In fact, the quantitative assessment of the aerosol properties
from ALC measurements and the relevant assimilation in meteorological
forecast models is amongst the main objectives of the EU COST Action TOPROF
("Towards operational ground-based profiling with ALCs, Doppler lidars and
microwave radiometers for improving weather forecasts"). Concurrently, the E-PROFILE program of the European
Meteorological Services Network (EUMETNET) focuses on the harmonization of
ALC measurements and data provision across Europe. Within these frameworks,
we implemented a model-assisted methodology to retrieve key aerosol
properties (extinction coefficient, surface area, and volume) from elastic
lidar and/or ALC measurements. The method is based on results from a large
set of aerosol scattering simulations (Mie theory) performed at UV, visible,
and near-IR wavelengths using a Monte Carlo approach to select the input
aerosol microphysical properties. An average "continental aerosol type"
(i.e., clean to moderately polluted continental aerosol conditions) is
addressed in this study. Based on the simulation results, we derive mean
functional relationships linking the aerosol backscatter coefficients to the
abovementioned variables. Applied in the data inversion of single-wavelength
lidars and/or ALCs, these relationships allow quantitative determination of
the vertically resolved aerosol backscatter, extinction, volume, and surface
area and, in turn, of the extinction-to-backscatter ratios (i.e., the
lidar ratios, LRs) and extinction-to-volume conversion factor
(cv) at 355, 532, and 1064 nm. These variables provide valuable
information for visibility, radiative transfer, and air quality applications.
This study also includes (1) validation of the model simulations with real
measurements and (2) test applications of the proposed model-based ALC
inversion methodology. In particular, our model simulations were compared to
backscatter and extinction coefficients independently retrieved by Raman
lidar systems operating at different continental sites within the European
Aerosol Research Lidar Network (EARLINET). This comparison shows good
model–measurement agreement, with LR discrepancies below 20 %. The
model-assisted quantitative retrieval of both aerosol extinction and volume
was then tested using raw data from three different ALCs systems
(CHM 15k Nimbus), operating within the Italian Automated LIdar-CEilometer
network (ALICEnet). For this purpose, a 1-year record of the ALC-derived
aerosol optical thickness (AOT) at each site was compared to direct AOT
measurements performed by colocated sun–sky photometers. This comparison
shows an overall AOT agreement within 30 % at all sites. At one site, the
model-assisted ALC estimation of the aerosol volume and mass (i.e.,
PM10) in the lowermost levels was compared to values measured at
the surface level by colocated in situ instrumentation. Within this
exercise, the ALC-derived daily-mean mass concentration was found to
reproduce the corresponding (EU regulated) PM10 values measured by
the local air quality agency well in terms of both temporal variability and
absolute values. Although limited in space and time, the good performances of
the proposed approach suggest it could possibly
represent a valid option to extend the capabilities of ALCs to provide
quantitative information for operational air quality and meteorological
monitoring
Aging, sex and cognitive Theory of Mind: a transcranial direct current stimulation study
Aging is accompanied by changes in cognitive abilities and a great interest is spreading among researchers about aging impact on social cognition skills, such as the Theory of Mind (ToM). Transcranial direct current stimulation (tDCS) has been used in social cognition studies founding evidence of sex-related different effects on cognitive ToM task in a young people sample. In this randomized, double-blind, sham-controlled study, we applied one active and one sham tDCS session on the medial prefrontal cortex (mPFC) during a cognitive ToM task, including both social (i.e., communicative) and nonsocial (i.e., private) intention attribution conditions, in sixty healthy aging individuals (30 males and 30 females). In half of the participants the anode was positioned over the mPFC, whereas in the other half the cathode was positioned over the mPFC. The results showed that: (i) anodal tDCS over the mPFC led to significant slower reaction times (vs. sham) for social intention attribution task only in female participants; (ii) No effects were found in both females and males during cathodal stimulation. We show for the first time sex-related differences in cognitive ToM abilities in healthy aging, extending previous findings concerning young participants
Observations of AtmosphericGravity Waves using Airglow All-sky CCD Imager At Cachoeira Paulista (23° S, 45° W)
An all-sky CCD imager for OH, O2 and OI (557.7 nm) airglow was operated at Cachoeira Paulista (CP), Brazil, (23° S, 45° W), from October 1998 to September 1999, with Utah State University. Dominant gravity wave components are extracted and seasonal variations are investigated. These waves have typically short horizontal wavelengths (5 - 60 km), short periods (5 - 35 minutes), and horizontal phase speeds of 1 - 80 m/s. Band-type waves of horizontal wavelength between 10 and 60 km showed clear seasonal dependence in the horizontal propagation direction to southeast in summer and to northwest in winter. The direction of propagation changed in mid-March and at the end of September. The gravity waves over CP may be generated by the strong tropospheric convection. In summer, this region extends along a line approximately between (10° S, 45° W) and (40° S, 78° W), from northern Argentina to the Brazilian northeast, with an accentuated distribution over central Brazil. CP is below this region. In winter, the convective region is located below CP mainly over the sea and there is no convection in central Brazil region above CP. Thus the anisotropy of the wave propagation direction is mainly due to source location and wave filtering by stratospheric winds
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