Expression of transforming growth factor ? and its correlation with lipodystrophy in oral submucous fibrosis: an immunohistochemical study

Objective: In our routine review of Oral Submucous Fibrosis (OSMF) biopsies, we observed decreased adipose tissue even though most are from buccal mucosa. Pathogenesis of OSMF has demonstrated the role of Transforming Growth Factor ? (TGF ?), in causing fibrosis. This study aims to correlate the role of TGF ? with loss of adipose tissue in OSMF. Study Design: From our archives, 84 OSMF cases (24 early and 60 advanced OSMF) were screened for adipose tissue. Immunoexpression of TGF ? in these cases were investigated. Results: Adipose tissue was seen in 67% of early OSMF and in 13% of advanced cases. Early cases showed more intense TGF ? staining of epithelium, fibroblast, macrophages and inflammatory cells than the advanced cases. Conclusion: These findings suggest that TGF ? plays a key role in causing lipodystrophy in OSMF and is secreted more during early course of the disease than in advanced stage

Analysis of Chlorophyll Content and Its Correlation with Yield Attributing Traits on Early Varieties of Maize (Zea Mays L.)

Chlorophyll has direct roles on photosynthesis and hence closely relates to capacity for photosynthesis, development and yield of crops. With object to explore the roles of chlorophyll content and its relation with other yield attributing traits a field research was conducted using fourteen early genotypes of maize in RCBD design with three replications. Observations were made for Soil Plant Analysis Development (SPAD) reading, ear weight, number of kernel row/ear, number of kernel/row, five hundred kernel weight and grain yield/hectare and these traits were analyzed using Analysis of Variance (ANOVA) and correlation coefficient analysis. SPAD reading showed a non-significant variation among the genotypes while it revealed significant correlation with no. of kernel/row, grain yield/hectare and highly significant correlation with no. of kernel row/ear and ear weight which are the most yield determinative traits. For the trait grain yield/ha followed by number of kernel row/ear genotype ARUN-1EV has been found comparatively superior to ARUN-2 (standard check). Grain Yield/hectare was highly heritable (>0.6) while no. of kernel / row, SPAD reading, ear weight, number of kernel row/ear were moderately heritable (0.3-0.6). Correlation analysis and ANOVA revealed ARUN-1EV, comparatively superior to ARUN-2 (standard check), had higher SPAD reading than mean SPAD reading with significant correlation with no. of kernel/row, no. of kernel row/ear, ear weight and grain yield/ha which are all yield determinative traits . This showed positive and significant effect of chlorophyll content in grain yield of the maize.Journal of Maize Research and Development (2015) 1(1):134-145DOI: http://dx.doi.org/10.5281/zenodo.3426

Stack Contention-alleviated Precharge Keeper for Pseudo Domino Logic

The dynamic circuits are supposed to offer superior speed and low power dissipation over static CMOS circuits. The domino logic circuits are used for high system performance but suffer from the precharge pulse degradation. This article provides different design topologies on the domino circuits to overcome the charge sharing and charge leakage with reference to the power dissipation and delay. The precharge keeper circuit has been proposed such that the keeper transistors also work as the precharge transistors to realize multiple output function. The performance improvement of the circuit\u27s analysis have been done for adders and logic gates using HSPICE tool. The proposed keeper techniques reveal lower power dissipation and lesser delay over the standard keeper circuit with less transistor count for different process variation

Optimization of Rotational Speed for Casting Al-Si Alloy Using Centrifugal Casting

An alloy is a material that has metallic properties and is formed by combination of two or more chemical elements of which at least one is a metal. Commonly, alloys have different properties from those of the component elements.In recent years aluminium alloys are widely used in automotive industries. This is particularly due to the real need to weight saving for more reduction of fuel consumption. The typical alloying elements are copper, magnesium, manganese, silicon, and zinc.Aluminium-Silicon alloys are of greater importance to engineering industries as they exhibit high strength to weight ratio, high wear resistance, low density, low coefficient of thermal expansion etc. Silicon imparts high fluidity and low shrinkage, which result in good cast ability and weldability.nbs

EcoCyc: fusing model organism databases with systems biology.

EcoCyc (http://EcoCyc.org) is a model organism database built on the genome sequence of Escherichia coli K-12 MG1655. Expert manual curation of the functions of individual E. coli gene products in EcoCyc has been based on information found in the experimental literature for E. coli K-12-derived strains. Updates to EcoCyc content continue to improve the comprehensive picture of E. coli biology. The utility of EcoCyc is enhanced by new tools available on the EcoCyc web site, and the development of EcoCyc as a teaching tool is increasing the impact of the knowledge collected in EcoCyc

Preservice Elementary Teachers’ Science Self-Efficacy Beliefs and Science Content Knowledge

Self-efficacy beliefs that relate to teachers’ motivation and performance have been an important area of concern for preservice teacher education. Research suggests high-quality science coursework has the potential to shape preservice teachers’ science self-efficacy beliefs. However, there are few studies examining the relationship between science self-efficacy beliefs and science content knowledge. The purpose of this mixed methods study is to investigate changes in preservice teachers’ science self-efficacy beliefs and science content knowledge and the relationship between the two variables as they co-evolve in a specialized science content course. Results from pre- and post-course administrations of the Science Teaching Efficacy Belief Instrument-B (Bleicher, 2004) and a physical science concept test along with semistructured interviews, classroom observations, and artifacts served as data sources for the study. The 18 participants belonged to three groups representing low, medium, and high initial levels of self-efficacy beliefs. A repeated measures multivariate analysis of variance design was used to test the significance of differences between the pre- and post-surveys across time. Results indicated statistically significant gains in participants’ science self-efficacy beliefs and science conceptual understandings. Additionally, a positive moderate relationship between gains in science conceptual understandings and gains in personal science teaching efficacy beliefs was found. Qualitative analysis of the participants’ responses indicated positive shifts in their science teacher self-image, and they credited their experiences in the course as sources of new levels of confidence to teach science. The study includes implications for preservice teacher education programs, science teacher education, and research