The lived experience of dysphagia following non-surgical treatment for head and neck cancer

The prevalence and severity of dysphagia in people treated non-surgically for primary head and neck cancer (HNC) is well documented. However, few studies have looked beyond the physiological impairment to explore the lived experience of dysphagia in the post-treatment period of HNC. The current study adopted a person-centred, qualitative approach to describe the experiences of people living with dysphagia in the months and years following non-surgical treatment for HNC. Using maximum variation sampling, 24 participants who had undergone radiotherapy treatment for HNC were recruited. Individual interviews were conducted to explore the impact of dysphagia on participants' everyday lives. The themes identified included: (1) physical changes related to swallowing; (2) emotions evoked by living with dysphagia; (3) altered perceptions and changes in appreciation of food; and (4) personal and lifestyle impacts. The data revealed the breadth and significance of the impact of dysphagia on the lives of people treated curatively for HNC. Assessment and management in the post-treatment period must be sufficiently holistic to address both the changing physical states and the psychosocial needs of people with dysphagia following HNC. Rehabilitation services which focus only on impairment-based management will fail to fully meet the support needs of this clinical population

Physiological changes to the swallowing mechanism following (Chemo)radiotherapy for head and neck cancer: a systematic review

Emerging research suggests that preventative swallowing rehabilitation, undertaken before or during (chemo)radiotherapy ([C]RT), can significantly improve early swallowing outcomes for head and neck cancer (HNC) patients. However, these treatment protocols are highly variable. Determining specific physiological swallowing parameters that are most likely to be impacted post-(C)RT would assist in refining clear targets for preventative rehabilitation. Therefore, this systematic review (1) examined the frequency and prevalence of physiological swallowing deficits observed post-(C)RT for HNC, and (2) determined the patterns of prevalence of these key physiological deficits over time post-treatment. Online databases were searched for relevant papers published between January 1998 and March 2013. A total of 153 papers were identified and appraised for methodological quality and suitability based on exclusionary criteria. Ultimately, 19 publications met the study’s inclusion criteria. Collation of reported prevalence of physiological swallowing deficits revealed reduced laryngeal excursion, base-of-tongue (BOT) dysfunction, reduced pharyngeal contraction, and impaired epiglottic movement as most frequently reported. BOT dysfunction and impaired epiglottic movement showed a collective prevalence of over 75 % in the majority of patient cohorts, whilst reduced laryngeal elevation and pharyngeal contraction had a prevalence of over 50 %. Subanalysis suggested a trend that the prevalence of these key deficits is dynamic although persistent over time. These findings can be used by clinicians to inform preventative intervention and support the use of specific, evidence-based therapy tasks explicitly selected to target the highly prevalent deficits post-(C)RT for HNC

Fair game: exploring the dynamics, perception and environmental impact of ‘surplus’ wild foods in England 10kya-present

This paper brings together zooarchaeological data from Neolithic to Post-medieval sites in England to explore the plasticity of cultural attitudes to the consumption of wild animals. It shows how, through time, game has been considered variously as ‘tabooed’ and ‘edible’, each having implications for patterns of biodiversity and wildlife management. The essential points being made are that deeper-time studies can reveal how human perceptions of ‘surplus foods’ have the potential to both create and remedy problems of environmental sustainability and food security. Perhaps more significantly, this paper argues that understanding the bio-cultural past of edible wild animal species has the potential to transform human attitudes to game in the present. This is important at a time when food security and the production of surplus are pressing national and global concerns

Swallowing, nutrition and patient-rated functional outcomes at 6 months following two non-surgical treatments for T1-T3 oropharyngeal cancer

Altered fractionation radiotherapy with concomitant boost (AFRT-CB) may be considered an alternative treatment for patients not appropriate for chemoradiation (CRT). As functional outcomes following AFRT-CB have been minimally reported, this exploratory paper describes the outcomes of patients managed with AFRT-CB or CRT at 6 months post-treatment

The ‘mosaic habitat’ concept in human evolution: past and present

The habitats preferred by hominins and other species are an important theme in palaeoanthropology, and the ‘mosaic habitat’ (also referred to as habitat heterogeneity) has been a central concept in this regard for the last four decades. Here we explore the development of this concept – loosely defined as a range of different habitat types, such as woodlands, riverine forest and savannah within a limited spatial area– in studies of human evolution in the last sixty years or so. We outline the key developments that took place before and around the time when the term ‘mosaic’ came to wider palaeoanthropological attention. To achieve this we used an analysis of the published literature, a study of illustrations of hominin evolution from 1925 onwards and an email survey of senior researchers in palaeoanthropology and related fields. We found that the term mosaic starts to be applied in palaeoanthropological thinking during the 1970’s due to the work of a number of researchers, including Karl Butzer and Glynn Isaac , with the earliest usage we have found of ‘mosaic’ in specific reference to hominin habitats being by Adriaan Kortlandt (1972). While we observe a steady increase in the numbers of publications reporting mosaic palaeohabitats, in keeping with the growing interest and specialisation in various methods of palaeoenvironmental reconstruction, we also note that there is a lack of critical studies that define this habitat, or examine the temporal and spatial scales associated with it. The general consensus within the field is that the concept now requires more detailed definition and study to evaluate its role in human evolution

Daily Light Integral and Nutrient Solution Electrical Conductivity for Tomato and Bell Pepper Seedling Production in an Indoor Vertical Farm with Artificial Lighting

Indoor vertical farms (IVFs) provide the conditions for producing seedlings of good quality. However, their effectiveness depends on the daily light integral (DLI) and nutrient management. This study examined the effects of DLI and nutrient solution electrical conductivity (EC) on tomato and bell pepper seedlings produced in an IVF or a greenhouse. Seedlings in the greenhouse were harvested 45 (tomato) and 55 (bell pepper) days after sowing, while those in the IVF were harvested after 30 and 40 days, respectively. The optimal EC was 2.0 for tomato and 2.4 dS m−1 for bell pepper. Tomato seedlings showed a decreased shoot-to-root ratio in the IVF. Tomatoes in the IVF reached 241% higher total biomass than greenhouse seedlings at 31.7 mol m−2 d−1, while bell peppers had an increase of 333% at 39.6 mol m−2 d−1; however, a DLI of 23.7 mol m−2 d−1 was enough to cause an increase of 153% and 264%, respectively. Nutrient concentration decreased in IVF seedlings, which was attributed to a dilution effect; in contrast, the nutrient content of tomato and bell pepper were highest when grown in the IVF when irrigated with solutions at 2.0 dS m−1 and a DLI of 31.7 mol m−2 d−1.fals

Subirrigation of container-grown tomato II: Physical and chemical properties of the growing medium

Subirrigation of containerized vegetable crops is a promising strategy to increase water and nutrient use efficiency, however, the longer growing seasons for cultivation of vegetable species may cause marked changes in the physical and chemical substrate properties. This study determined the effects of the irrigation system, subirrigation vs. drip-irrigation, and the concentration of the nutrient solution on the substrate physical and chemical properties in containerized tomato plants. Plants were irrigated with solutions at concentrations of -0.072, -0.058 and -0.043 MPa. Root dry weight of subirrigated plants was decreased by 35% in the substrate top layer when the highest concentration was used. Substrate electrical conductivity increased while pH was acidified as solution concentration increased and from the bottom to the top substrate layers in subirrigated plants. Salts buildup was associated with increased concentration of oxalic and tartaric acids and pH acidification. The improved substrate physical and chemical properties in subirrigated plants were associated with higher fruit yield (11.0 kg per plant) provided nutrient solution concentration was reduced to -0.043 MPa; in contrast, the highest yield in drip-irrigated plants (10.1 kg per plant) was obtained when the solution concentration was -0.072 MPa. In conclusion, subirrigation with reuse of the nutrient solution is a promising strategy to reduce water waste through runoff and leaching as water use efficiency increases due to greater water retention properties in the substrate, the maintenance of an EC within a range the plants can tolerate, and a lower acidification of substrate pH.fals

The mismeasure of ape social cognition

In his classic analysis, The Mismeasure of Man, Gould (1981) demolished the idea that intelligence was an inherent, genetic trait of different human groups by emphasizing, among other things, (a) its sensitivity to environmental input, (b) the incommensurate pre-test preparation of different human groups, and (c) the inadequacy of the testing contexts, in many cases. According to Gould, the root cause of these oversights was confirmation bias by psychometricians, an unwarranted commitment to the idea that intelligence was a fixed, immutable quality of people. By virtue of a similar, systemic interpretive bias, in the last two decades, numerous contemporary researchers in comparative psychology have claimed human superiority over apes in social intelligence, based on two-group comparisons between postindustrial, Western Europeans and captive apes, where the apes have been isolated from European styles of social interaction, and tested with radically different procedures. Moreover, direct comparisons of humans with apes suffer from pervasive lapses in argumentation: Research designs in wide contemporary use are inherently mute about the underlying psychological causes of overt behavior. Here we analyze these problems and offer a more fruitful approach to the comparative study of social intelligence, which focuses on specific individual learning histories in specific ecological circumstances

Make African grasslands climate-change resilient

Climate change has negatively impacted grassland productivity in Africa. Climate-smart technologies such as forage grass, legume, and herb mixtures could enhance grassland productivity and resilience, offering a sustainable solution for African pasture-based livestock systems

A frotarsius chatrathi, first tarsiiform primate (? Tarsiidae) from Africa

Tarsiiform primates have long been regarded as a Laurasian group, with an extensive fossil record in the Eocene of North America and EuropeI and two important but less well-known records from Asia