National Prison Entrants’ Bloodborne Virus & Risk Behaviour Survey 2004, 2007, And 2010

Prisoner populations are characterised by engagement in a range of risk behaviours, most notably injecting drug use. Consequently they are at an increased risk of exposure to blood-borne viruses such as hepatitis B, hepatitis C and HIV. Previous Australian research has shown that hepatitis C is between thirty to forty times higher among prisoners compared with the general community. Therefore, surveillance of this population to detect the presence of blood-borne pathogens and identify trends in risk behaviours is important in planning effective prevention strategies. This is the third prison entrants’ survey to have been conducted; the first was undertaken in 2004 and the second in 2007. The 2010 survey was enhanced to test for three sexually transmissible infections (STI) - chlamydia, gonorrhoea, and syphilis

Comparison of modern icing cloud instruments

Intercomparison tests with Particle Measuring Systems (PMS) were conducted. Cloud liquid water content (LWC) measurements were also taken with a Johnson and Williams (JW) hot-wire device and an icing rate device (Leigh IDS). Tests include varying cloud LWC (0.5 to 5 au gm), cloud median volume diameter (MVD) (15 to 26 microns), temperature (-29 to 20 C), and air speeds (50 to 285 mph). Comparisons were based upon evaluating probe estimates of cloud LWC and median volume diameter for given tunnel settings. Variations of plus or minus 10% and plus or minus 5% in LWC and MVD, respectively, were determined of spray clouds between test made at given tunnel settings (fixed LWC, MVD, and air speed) indicating cloud conditions were highly reproducible. Although LWC measurements from JW and Leigh devices were consistent with tunnel values, individual probe measurements either consistently over or underestimated tunnel values by factors ranging from about 0.2 to 2. Range amounted to a factor of 6 differences between LWC estimates of probes for given cloud conditions. For given cloud conditions, estimates of cloud MVD between probes were within plus or minus 3 microns and 93% of the test cases. Measurements overestimated tunnel values in the range between 10 to 20 microns. The need for improving currently used calibration procedures was indicated. Establishment of test facility (or facilities) such as an icing tunnel where instruments can be calibrated against known cloud standards would be a logical choice

Proposed plant host test list for assessing the risk of biological control agents for Clidemia hirta (L.) D.Don.

Background The following proposed plant host list is for the testing of potential biological control agents of Clidemia hirta (L.) D. Don (Melastomataceae). Post-release evidence from other countries suggests a promising outlook for biological control of C. hirta in Australia. Seven agents have already been released in Hawaii for this purpose, with six of these becoming established (Nakahara et al. 1992). Liothrips urichi Karny (Thysanoptera: Phlaeothripidae) is the first candidate biological control species proposed to undergo testing in Australia. The thrips have been released as a biological control agent for C. hirta in Fiji (1930), the Solomon Islands (1938, 1973 and 1975), Hawaii (1953), Palau (1960 and 1972), and American Samoa (1974) (Conant 2009). Liothrips urichi has established in all but the Solomon Islands and appears to be effective in open, sunny areas (Conant 2009). Host specificity of this insect has been demonstrated both within its native range and within countries where it has been introduced as a biological control of C. hirta (Table 1)

Sexual experience, relationships, and factors associated with sexual and romantic satisfaction in the first Australian Trans & Gender Diverse Sexual Health Survey

Background: Sexual and romantic satisfaction are important aspects of sexual health and wellbeing, but they have not been thoroughly investigated among transgender and gender diverse (‘trans’) people in Australia. Aims: To address this gap and improve sexual health and wellbeing, we assessed the sexual behavior and relationships of a national sample of trans people in Australia, and factors associated with sexual and romantic satisfaction. Methods: We conducted a national survey of trans people from Australia in October-November 2018. Results: The sample included 1,613 trans participants, of whom 353 (21.9%) were men, 397 (24.6%) were women and 863 (53.5%) were non-binary. Over 70% of the sample had been sexually active in the previous year, and 56.9% were in a relationship, but only 32.4% were satisfied with the sexual aspects and 47.1% with the romantic aspects of their lives. Sexual satisfaction was associated with younger age, being asexual, having more trans friends, more frequent sex, and using illicit drugs in the context of sexual activity. Anxiety or fear about sex was associated with less sexual satisfaction, as was being in an open relationship. Romantic satisfaction was associated with younger age, having non-binary partners, and being in a current relationship (particularly a monogamous one). Recent distress, anxiety, or fear about sex were associated with less romantic satisfaction. Conclusion: Participants reported a broad range of sexual relationships, but low levels of satisfaction with the sexual and romantic aspects of their lives. The findings underscore the importance of supportive partners, access to social support and peer networks of trans people, as well as access to mental health support and sex-positive, trans affirming counseling in sexual health services

Considerations for the development of mobile phone apps to support diabetes self-management: systematic review

Background: There is increased research interest in the use of mobile phone apps to support diabetes management. However,there are divergent views on what constitute the minimum standards for inclusion in the development of mobile phone apps. Mobile phone apps require an evidence-based approach to development which will consequently impact on their effectiveness. Therefore, comprehensive information on developmental considerations could help designers and researchers to develop innovative and effective patient-centered self-management mobile phone apps for diabetes patients. Objective: This systematic review examined the developmental considerations adopted in trials that engaged mobile phone applications for diabetes self-management. Methods: A comprehensive search strategy was implemented across 5 electronic databases; Medline, Scopus, Social Science Citation Index, the Cochrane Central Register of Controlled Trials and Cumulative Index of Nursing and Allied Health Literature (CINALHL) and supplemented by reference list from identified studies. Study quality was evaluated using the Joanna Briggs Critical appraisal checklist for trials. Information on developmental factors (health behavioral theory, functionality, pilot testing,user and clinical expert involvements, data privacy and app security) were assessed across experimental studies using a template developed for the review. Results: A total of 11 studies (10 randomized controlled trials and 1 quasi-experimental trial) that fitted the inclusion criteria were identified. All the included studies had the functionality of self-monitoring of blood glucose. However, only some of them included functions for data analytics (7/11, 63.6%), education (6/11, 54.5%) and reminder (6/11, 54.5%). There were 5/11(45.5%) studies with significantly improved glycosylated hemoglobin in the intervention groups where educational functionality was present in the apps used in the 5 trials. Only 1 (1/11, 9.1%) study considered health behavioral theory and user involvement, while 2 (2/11, 18.1%) other studies reported the involvement of clinical experts in the development of their apps. There were 4 (4/11, 36.4%) studies which referred to data security and privacy considerations during their app development while 7 (7/12, 63.6%) studies provided information on pilot testing of apps before use in the full trial. Overall, none of the studies provided information on all developmental factors assessed in the review. Conclusions: There is a lack of elaborate and detailed information in the literature regarding the factors considered in the development of apps used as interventions for diabetes self-management. Documentation and inclusion of such vital information will foster a transparent and shared decision-making process that will ultimately lead to the development of practical and user-friendly self-management apps that can enhance the quality of life for diabetes patients

Female choice over short and long distances: Neighbour effects.

Abstract Fiddler crabs live at high densities and matesearching females encounter many males at varying distances. Who is the ideal neighbour for a male? There could be a trade-off if having neighbours that invest more in sexual signals increases the rate at which females initially move towards a focal male, but thereafter decrease the likelihood that he is chosen rather than his neighbour. We used robotic crabs to test whether female choice for focal males (identical claw size/courtship wave rate) varied depending on the relative investment in sexual signals of their two neighbours and the distance at which she first saw the males. The neighbours' phenotype did not affect which of two focal males she initially approached from long-range (50 cm). When a female initially saw a trio of males at a close-range (20 cm), she preferentially chose the focal male over neighbours that invested less in sexual signals (smaller claw/slower wave rate), but did not show a preference for the focal male over neighbours that invested more in sexua

The Dynamics of a Meandering River

We present a statistical model of a meandering river on an alluvial plane which is motivated by the physical non-linear dynamics of the river channel migration and by describing heterogeneity of the terrain by noise. We study the dynamics analytically and numerically. The motion of the river channel is unstable and we show that by inclusion of the formation of ox-bow lakes, the system may be stabilised. We then calculate the steady state and show that it is in agreement with simulations and measurements of field data.Comment: Revtex, 12 pages, 2 postscript figure

Longitudinal cohort of HIV-negative transgender women of colour in New York City: protocol for the TURNNT ('Trying to Understand Relationships, Networks and Neighbourhoods among Transgender women of colour') study.

IntroductionIn the USA, transgender women are among the most vulnerable to HIV. In particular, transgender women of colour face high rates of infection and low uptake of important HIV prevention tools, including pre-exposure prophylaxis (PrEP). This paper describes the design, sampling methods, data collection and analyses of the TURNNT ('Trying to Understand Relationships, Networks and Neighbourhoods among Transgender women of colour') study. In collaboration with communities of transgender women of colour, TURNNT aims to explore the complex social and environmental (ie, neighbourhood) structures that affect HIV prevention and other aspects of health in order to identify avenues for intervention.Methods and analysesTURNNT is a prospective cohort study, which will recruit 300 transgender women of colour (150 Black/African American, 100 Latina and 50 Asian/Pacific Islander participants) in New York City. There will be three waves of data collection separated by 6 months. At each wave, participants will provide information on their relationships, social and sexual networks, and neighbourhoods. Global position system technology will be used to generate individual daily path areas in order to estimate neighbourhood-level exposures. Multivariate analyses will be conducted to assess cross-sectional and longitudinal, independent and synergistic associations of personal relationships (notably individual social capital), social and sexual networks, and neighbourhood factors (notably neighbourhood-level social cohesion) with PrEP uptake and discontinuation.Ethics and disseminationThe TURNNT protocol was approved by the Columbia University Institutional Review Board (reference no. AAAS8164). This study will provide novel insights into the relationship, network and neighbourhood factors that influence HIV prevention behaviours among transgender women of colour and facilitate exploration of this population's health and well-being more broadly. Through community-based dissemination events and consultation with policy makers, this foundational work will be used to guide the development and implementation of future interventions with and for transgender women of colour

Sedimentation in an artificial lake -Lake Matahina, Bay of Plenty

Lake Matahina, an 8 km long hydroelectric storage reservoir, is a small (2.5 km2), 50 m deep, warm monomictic, gorge-type lake whose internal circulation is controlled by the inflowing Rangitaiki River which drains a greywacke and acid volcanic catchment. Three major proximal to distal subenvironments are defined for the lake on the basis of surficial sediment character and dominant depositional process: (a) fluvial-glassy, quartzofeld-spathic, and lithic gravel-sand mixtures deposited from contact and saltation loads in less than 3 m depth; (b) (pro-)deltaic-quartzofeldspathic and glassy sand-silt mixtures deposited from graded and uniform suspension loads in 3-20 m depth; and (c) basinal-diatomaceous, argillaceous, and glassy silt-clay mixtures deposited from uniform and pelagic suspension loads in 20-50 m depth. The delta face has been prograding into the lake at a rate of 35-40 m/year and vertical accretion rates in pro-delta areas are 15-20 cm/year. Basinal deposits are fed mainly from river plume dispersion involving overflows, interflows, and underflows, and by pelagic settling, and sedimentation rates behind the dam have averaged about 2 cm/year. Occasional fine sand layers in muds of basinal cores attest to density currents or underflows generated during river flooding flowing the length of the lake along a sublacustrine channel marking the position of the now submerged channel of the Rangitaiki River

Outcome with lenalidomide plus dexamethasone followed by early autologous stem cell transplantation in patients with newly diagnosed multiple myeloma on the ECOG-ACRIN E4A03 randomized clinical trial: long-term follow-up

In Eastern Cooperative Oncology Group-ACRIN E4A03, on completion of four cycles of therapy, newly diagnosed multiple myeloma patients had the option of proceeding to autologous peripheral blood stem cell transplant (ASCT) or continuing on their assigned therapy lenalidomide plus low-dose dexamethasone (Ld) or lenalidomide plus high-dose dexamethasone (LD). This landmark analysis compared the outcome of 431 patients surviving their first four cycles of therapy pursuing early ASCT to those continuing on their assigned therapy. Survival distributions were estimated using the Kaplan–Meier method and compared with log-rank test. Ninety patients (21%) opted for early ASCT. The 1-, 2-, 3-, 4- an