144 research outputs found
Increasing partnerships between scientists and forest managers: Lessons from an ongoing interdisciplinary project in Quebec
Adaptive management presupposes stronger links between scientists and forest managers in order to adapt research processes and findings to production activities. Partnerships between these two groups are starting to emerge in the forest sector in Quebec. However, local forest managers have not always had the occasion in the past to contribute to research processes. Moreover, scientists have not always had the opportunity to harmonize all their respective research projects ar the local level. This research project was thus aimed ar establishing a link between local forest managers and scientists in order to direct research projects towards local needs and concerns. The purpose of establishing this contact between local forest managers and scientists was to create opportunities for inter-disciplinary research projects. This experiment demonstrated that the roles and attitudes of scientists and forest managers still need to evolve in order to increase the chances for successful partnerships between these two groups. On the one hand, forest managers need to view research (1) as part of their daily activities and (2) as bringing benefit in the long-term. On the other hand scientists must (1) invest time in understanding what the forest managers are doing and (2) consider forest managers as equal partners with useful knowledge and skills in developing the research questions and protocols
Insights into interfacial activation from an open structure of Candida rugosa lipase.
The structure of the Candida rugosa lipase determined at 2.06-A resolution reveals a conformation with a solvent-accessible active site. Comparison with the crystal structure of the homologous lipase from Geotrichum candidum, in which the active site is covered by surface loops and is inaccessible from the solvent, shows that the largest structural differences occur in the vicinity of the active site. Three loops in this region differ significantly in conformation, and the interfacial activation of these lipases is likely to be associated with conformational rearrangements of these loops. The "open" structure provides a new image of the substrate binding region and active site access, which is different from that inferred from the structure of the "closed" form of the G. candidum lipase
Development of integrated ecological standards of sustainable forest management at an operational scale
Within Canada, and internationally, an increasing demand that forests be managed to maintain all resources has led to the development of criteria and indicators of sustainable forest management. There is, however, a lack of understanding, at an operational scale, how to evaluate and compare forest management activities to ensure the sustainability of all resources. For example, nationally, many of the existing indicators are too broad to be used directly at a local scale of forest management; provincially, regulations are often too prescriptive and rigid to allow for adaptive management; and forest certification programs, often based largely on public or stake-holder opinion instead of scientific understanding, may be too local in nature to permit a comparison of operations across a biome. At an operational scale indicators must be relevant to forest activities and ecologically integrated. In order to aid decision-makers in the adaptive management necessary for sustainable forest management, two types of indicators are identified: those that are prescriptive to aid in planning forest management and those that are evaluative to be used in monitoring and suggesting improvements. An integrated approach to developing standards based on an ecosystem management paradigm is outlined for the boreal forest where the variability inherent in natural systems is used to define the limits within which forest management is ecologically sustainable. Sustainability thresholds are thus defined by ecosystem response after natural disturbances. For this exercise, standards are proposed for biodiversity, forest productivity via regeneration, soil conservation and aquatic resources. For each of these standards, planning indicators are developed for managing forest conditions while forest values are evaluated by environmental indicators, thus leading to a continuous cycle of improvement. Approaches to developing critical thresholds and corresponding prescriptions are also outlined. In all cases, the scale of evaluation is clearly related to the landscape (or FMU) level while the stand level is used for measurement purposes. In this view the forest should be managed as a whole even though forest interventions are usually undertaken at the stand level
The use of measured genotype information in the analysis of quantitative phenotypes in man.
We have begun a measured genotype approach to the genetic analysis of lipid and lipoprotein variability. This approach enables one to simultaneously estimate the frequencies and effects of alleles at specific loci along with the residual polygenetic variance component. In this study we consider the contribution of three common alleles at the locus coding for apolipoprotein E to interindividual variation of total cholesterol, betalipoprotein, and triglyceride levels. A sample of 102 nuclear families consisting of 434 individuals was studied. The frequencies of the ε2, ε3, and ε4 alleles in this sample are 0·137,0·740, and 0·123, respectively. In separate analyses of cholesterol and betalipoprotein levels, a complete model that includes the effects of the six apo E genotypes, unmeasured polygenes, and individual specific environmental effects fits these data significantly better than a reduced model that does not include the effects of the apo E polymorphism or a reduced model that does not include the effects of polygenes. On the average the ε2 allele lowers total cholesterol and betalipoprotein levels by 0·425 mmol/l and 0·811 units, respectively. The ε4 allele is associated with an average increase of these phenotypes by 0·255 mmol/l and 0·628 units, respectively. Simultaneous estimates of the interindividual variability of total cholesterol levels attributable to the apo E polymorphism and to residual polygenic effects are 8% and 56%, respectively. For betalipoprotein levels, we simultaneously estimate these values to be 7% and 42%, respectively. A reduced model including the effects of polygenes but not the effects of the apo E polymorphism fitted the triglyceride data as well as the complete model. The estimate of the fraction of interindividual variability associated with polygenetic effects was 26.5%. We review our present understanding of the genetic architecture underlying variability of cholesterol levels in the population at large and infer that the majority of the genetic variability may be accounted for by polymorphic gene loci with moderate effects on cholesterol levels.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65212/1/j.1469-1809.1987.tb00874.x.pd
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Accounting for information: Information and knowledge in the annual reports of FTSE 100 companies
The purpose of this study was to assess the ways in which a sample group of companies discuss information and knowledge.
Quantitative and qualitative content analyses were used to survey the way that companies present and value information and knowledge, based on the annual reports of the FTSE 100, the United Kingdom's largest publicly-listed companies. A novel content analysis approach is used, based on a set of categories proposed by Oppenheim, Stenson and Wilson.
Many of the companies analysed made explicit the importance of information and knowledge, through either discussion in the text of the annual report or through an attempt to assign a monetary value to information assets. Where the importance of information and knowledge was not made explicit, the study revealed links between successful performance and effective use of information assets. Different categories of information assets were identified within the annual reports.
Conclusions drawn from the analysis include that information and knowledge are demonstrably important to FTSE 100 companies, although the specific term “knowledge” does not appear to have a special significance in the companies’ lexicon; and that certain sectors, such as General Financial, General Retail, Travel & Leisure, Mining, Aerospace & Defence and Software & Computer Services, mention information and knowledge more than others
Consequences of various landscape-scale ecosystem management strategies and fire cycles on age-class structure and harvest in boreal forests
At the landscape scale, one of the key indicators of sustainable forest management is the age-class distribution of stands, since it provides a coarse synopsis of habitat potential, structural complexity, and stand volume, and it is directly modified by timber extraction and wildfire. To explore the consequences of several landscape-scale boreal forest management strategies on age-class structure in the Mauricie region of Quebec, we used spatially explicit simulation modelling. Our study investigated three different harvesting strategies (the one currently practiced and two different strategies to maintain late seral stands) and interactions between fire and harvesting on stand age-class distribution. We found that the legacy of initial forested age structure and its spatial configuration can pose short- (<50 years) to medium-term (150-300 years) challenges to balancing wood supply and ecological objectives. Also, ongoing disturbance by fire, even at relatively long cycles in relation to historic levels, can further constrain the achievement of both timber and biodiversity goals. For example, when fire was combined with management, harvest shortfalls occurred in all scenarios with a fire cycle of 100 years and most scenarios with a fire cycle of 150 years. Even a fire cycle of 500 years led to a reduction in older forest when its maintenance was not a primary constraint. Our results highlight the need to consider the broad-scale effects of natural disturbance when developing ecosystem management policies and the importance of prioritizing objectives when planning for multiple resource use
Individual Attachment Style Modulates Human Amygdala and Striatum Activation during Social Appraisal
Adult attachment style refers to individual personality traits that strongly influence emotional bonds and reactions to social partners. Behavioral research has shown that adult attachment style reflects profound differences in sensitivity to social signals of support or conflict, but the neural substrates underlying such differences remain unsettled. Using functional magnetic resonance imaging (fMRI), we examined how the three classic prototypes of attachment style (secure, avoidant, anxious) modulate brain responses to facial expressions conveying either positive or negative feedback about task performance (either supportive or hostile) in a social game context. Activation of striatum and ventral tegmental area was enhanced to positive feedback signaled by a smiling face, but this was reduced in participants with avoidant attachment, indicating relative impassiveness to social reward. Conversely, a left amygdala response was evoked by angry faces associated with negative feedback, and correlated positively with anxious attachment, suggesting an increased sensitivity to social punishment. Secure attachment showed mirror effects in striatum and amygdala, but no other specific correlate. These results reveal a critical role for brain systems implicated in reward and threat processing in the biological underpinnings of adult attachment style, and provide new support to psychological models that have postulated two separate affective dimensions to explain these individual differences, centered on the ventral striatum and amygdala circuits, respectively. These findings also demonstrate that brain responses to face expressions are not driven by facial features alone but determined by the personal significance of expressions in current social context. By linking fundamental psychosocial dimensions of adult attachment with brain function, our results do not only corroborate their biological bases but also help understand their impact on behavior
Use of anticoagulants and antiplatelet agents in stable outpatients with coronary artery disease and atrial fibrillation. International CLARIFY registry
A Web 2.0 como ferramenta de análise de tendências e monitorização do ambiente externo e sua relação com a cultura de convergência dos media
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