335 research outputs found
Inheritance patterns in citation networks reveal scientific memes
Memes are the cultural equivalent of genes that spread across human culture
by means of imitation. What makes a meme and what distinguishes it from other
forms of information, however, is still poorly understood. Our analysis of
memes in the scientific literature reveals that they are governed by a
surprisingly simple relationship between frequency of occurrence and the degree
to which they propagate along the citation graph. We propose a simple
formalization of this pattern and we validate it with data from close to 50
million publication records from the Web of Science, PubMed Central, and the
American Physical Society. Evaluations relying on human annotators, citation
network randomizations, and comparisons with several alternative approaches
confirm that our formula is accurate and effective, without a dependence on
linguistic or ontological knowledge and without the application of arbitrary
thresholds or filters.Comment: 8 two-column pages, 5 figures; accepted for publication in Physical
Review
Association Between Maternal Diabetes in Utero and Age at Offspring's Diagnosis of Type 2 Diabetes
OBJECTIVE—The purpose of this study was to examine age of diabetes diagnosis in youth who have a parent with diabetes by diabetes type and whether the parent's diabetes was diagnosed before or after the youth's birth
The repulsive lattice gas, the independent-set polynomial, and the Lov\'asz local lemma
We elucidate the close connection between the repulsive lattice gas in
equilibrium statistical mechanics and the Lovasz local lemma in probabilistic
combinatorics. We show that the conclusion of the Lovasz local lemma holds for
dependency graph G and probabilities {p_x} if and only if the independent-set
polynomial for G is nonvanishing in the polydisc of radii {p_x}. Furthermore,
we show that the usual proof of the Lovasz local lemma -- which provides a
sufficient condition for this to occur -- corresponds to a simple inductive
argument for the nonvanishing of the independent-set polynomial in a polydisc,
which was discovered implicitly by Shearer and explicitly by Dobrushin. We also
present some refinements and extensions of both arguments, including a
generalization of the Lovasz local lemma that allows for "soft" dependencies.
In addition, we prove some general properties of the partition function of a
repulsive lattice gas, most of which are consequences of the alternating-sign
property for the Mayer coefficients. We conclude with a brief discussion of the
repulsive lattice gas on countably infinite graphs.Comment: LaTex2e, 97 pages. Version 2 makes slight changes to improve clarity.
To be published in J. Stat. Phy
Complete O(alpha_s^2) Corrections to (2+1) Jet Cross Sections in Deep Inelastic Scattering
Complete next-to leading order QCD predictions for (2+1) jet cross sections
and jet rates in deep inelastic scattering (DIS) based on a new parton level
Monte Carlo program are presented. All relevant helicity contributions to the
total cross section are included. Results on total jet cross sections as well
as differential distributions in the basic kinematical variables and
are shown for HERA energies and for the fixed target experiment E665 at
FERMILAB. We study the dependence on the choices of the renormalization scale
and the factorization scale and show that the NLO results are
much less sensitive to the variation of than the LO results.
The effect of an additional cut to our jet definition scheme is
investigated.Comment: 14 pages, LateX, MAD/PH/821, 15 figures (not included), figures are
available upon request. (some essential changes to the figures, minor changes
to the text). To appear in Z.Phys.
Intron RNA editing is essential for splicing in plant mitochondria
Most plant mitochondria messenger RNAs (mRNAs) undergo editing through C-to-U conversions located mainly in exon sequences. However, some RNA editing events are found in non-coding regions at critical positions in the predicted secondary and tertiary structures of introns, suggesting that RNA editing could be important for splicing. Here, we studied the relationships between editing and splicing of the mRNA encoding the ribosomal protein S10 (rps10), which has a group II intron and five editing sites. Two of them, C2 and C3, predicted to stabilize the folded structure of the intron necessary for splicing, were studied by using rps10 mutants introduced into isolated potato mitochondria by electroporation. While mutations of C2 involved in EBS2/IBS2 interactions did not affect splicing, probably by the presence of an alternative EBS2′ region in domain I of the intron, the edition of site C3 turned out to be critical for rps10 mRNA splicing; only the edited (U) form of the transcript was processed. Interestingly, RNA editing was strongly reduced in transcripts from two different intronless genes, rps10 from potato and cox2 from wheat, suggesting that efficient RNA processing may require a close interaction of factors engaged in different maturation processes. This is the first report linking editing and splicing in conditions close to the in vivo situation
Different paths to the modern state in Europe: the interaction between domestic political economy and interstate competition
Theoretical work on state formation and capacity has focused mostly on early modern Europe and on the experience of western European states during this period. While a number of European states monopolized domestic tax collection and achieved gains in state capacity during the early modern era, for others revenues stagnated or even declined, and these variations motivated alternative hypotheses for determinants of fiscal and state capacity. In this study we test the basic hypotheses in the existing literature making use of the large date set we have compiled for all of the leading states across the continent. We find strong empirical support for two prevailing threads in the literature, arguing respectively that interstate wars and changes in economic structure towards an urbanized economy had positive fiscal impact. Regarding the main point of contention in the theoretical literature, whether it was representative or authoritarian political regimes that facilitated the gains in fiscal capacity, we do not find conclusive evidence that one performed better than the other. Instead, the empirical evidence we have gathered lends supports to the hypothesis that when under pressure of war, the fiscal performance of representative regimes was better in the more urbanized-commercial economies and the fiscal performance of authoritarian regimes was better in rural-agrarian economie
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